Anemia, Sickle CellSickle Cell TraitHemoglobin, SickleErythrocytes, AbnormalAntisickling AgentsHemoglobin SC DiseaseFetal HemoglobinQuantitative Trait, HeritableHydroxyureaThalassemiabeta-ThalassemiaHemoglobinopathiesJamaicaErythrocytesAcute Chest SyndromeHemoglobin C Diseasealpha-ThalassemiaHemoglobinsHemoglobin AGene Expression ProfilingHemolysisHemoglobin CPhenotypeBlood TransfusionExchange Transfusion, Whole BloodLeg UlcerHemoglobins, AbnormalErythrocyte DeformabilityGlobinsGene Expression RegulationGenetic TherapySplenic InfarctionPainOligonucleotide Array Sequence AnalysisErythrocyte CountGenotypeGenetic VectorsErythrocyte IndicesChromosome MappingVascular DiseasesGenetic MarkersErythrocyte AgingErythrocyte MembraneHomozygoteBreedingLentivirusCrosses, GeneticBlood ViscosityReticulocytesHematopoietic Stem CellsModels, GeneticErythrocyte TransfusionOxyhemoglobinsErythrocyte AggregationCells, Culturedbeta-GlobinsOxygenGene Expressiongamma-GlobinsX-Linked Combined Immunodeficiency DiseasesCumulus CellsHematocritHemorheologyKidney Papillary NecrosisDimethyl AdipimidateLutheran Blood-Group SystemNigeriaGrowth Differentiation Factor 3Genetic VariationMice, TransgenicRetroviridaeSplenic DiseasesCell DifferentiationRNA, MessengerHyphemaHemoglobin A2Gene Transfer TechniquesNeonatal ScreeningRetinal DiseasesGenetic LinkagePriapismTime FactorsMolecular Sequence DataPolymorphism, Single NucleotideErythrocyte InclusionsTransduction, Genetic2,3-DiphosphoglycerateMediterranean IslandsIron OverloadBase SequencePregnancy Complications, HematologicMice, Inbred C57BLHypertension, PulmonaryPremarital ExaminationsReverse Transcriptase Polymerase Chain ReactionStem CellsEnuresisAnemia, HemolyticEpistasis, GeneticTricuspid Valve Insufficiency