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  • Clinical
  • In a randomized, two-period, two-sequence crossover clinical trial, we analyzed 31 stable asthmatic children (6-18 yrs of age) on two consecutive days, who were randomly assigned to receive 100 μg of albuterol MDI through either a locally produced valved spacer or a non-valved spacer. (nih.gov)
  • bronchodilator
  • The aim of this study was to compare the bronchodilator response to albuterol administered by MDI with and without a valved spacer. (nih.gov)
  • No significant differences in the absolute change in FEV(1) (0.20 ± 0.17 vs. 0.18 ± 0.16, p = 0.63), FVC (0.07 ± 0.13 vs. 0.07 ± 0.16, p = 0.88), or MMEF (0.49 ± 0.31 vs. 0.43 ± 0.39, p = 0.53) after bronchodilator administration were found between the use of valved and non-valved spacers. (nih.gov)
  • In stable asthmatic children, albuterol administered through MDI using a non-valved spacer produces a bronchodilator response similar to that of a spacer with a valve that requires an inhalatory opening pressure (with flows between 2 and 32 l/min) that even toddlers with bronchial obstruction can easily generate. (nih.gov)
  • breaths
  • 001). The mean difference in improvement in PEF between the single maximal inhalation with a breath-hold and 5 tidal breaths group was 30.0 ± 18.16 and 28.29 ± 13.94 L/min, respectively, and was not statistically significant ( P = .88). (rcjournal.com)
  • Devices
  • FP and BUD are both systemically active in children 1 to 3 years old when administered for 4 weeks from their dedicated spacer devices in daily doses of 400 μg with no difference between the 2 steroid regimens. (aappublications.org)
  • usually
  • In the step 1, the patient is given short acting beta 2 agonist as and when required, with that the patient usually remain all right, the need for inhalation for beta 2 agonist should not be regular. (lybrate.com)
  • method
  • Tidal breathing with a pMDI with spacer is as effective as the single breath method as per Scottish Intercollegiate Guidelines Network (SIGN) recommendations. (rcjournal.com)
  • and ensures that the inhalation method is appropriate for each patient. (ersjournals.com)
  • study
  • The primary goal of the study was to investigate the systemic activity of inhaled steroid in the clinically relevant daily dose of 400 μg delivered via dedicated spacers. (aappublications.org)