Inhalation exposures. Medical search. Frequent questions

2 Transmitted through inhalation or ingestion of rodent feces or urine. (cdc.gov)
Poisoning can result from mercury vapor inhalation, mercury ingestion, mercury injection, and absorption of mercury through the skin. (medscape.com)
Nerve agents are readily absorbed by inhalation, ingestion, and dermal contact. (cdc.gov)
The exposure can occur through different routes, such as inhalation, skin contact, or ingestion. (legalmatch.com)
Inhalation, ingestion, or skin contact with these substances can lead to a variety of health issues, from skin irritation and burns to respiratory issues, neurological damage, or cancer. (legalmatch.com)
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. (ilo.org)
In children, lead exposure often occurs through ingestion. (medlineplus.gov)
Thallium can be absorbed into the body by inhalation, ingestion, and skin contact. (cdc.gov)
Ingestion is an important route of exposure. (cdc.gov)
National Toxicology Program (NTP) studies indicate that ingestion of high doses of selenium sulfide causes liver tumors in rats and mice, but no adequate inhalation studies exist. (dguv.de)
Ingestion is a less common exposure pathway, but exposure can occur after swallowing of material cleared from the lungs. (cdc.gov)
The majority of intoxication reports of hydrocarbons are due to inhalation or ingestion, but a few case reports have described intravenous ingestion of gasoline for suicide. (medscape.com)

Notable human health toxicity effects identified from human and/or animal studies include respiratory cancer, non-cancer toxicity effects following inhalation, dermatitis, and reproductive effects. (mdpi.com)
Thallium was used historically as a rodenticide, but has since been banned in the United States due to its toxicity from accidental exposure. (cdc.gov)
The LRI C10 project aims to develop better tools for the identification of the inhalation toxicity of microplastics of different origin/with different properties. (cefic-lri.org)
Two primary organ systems are affected by inhalation hydrocarbon toxicity: the CNS and the cardiopulmonary system. (medscape.com)

Because it is a gas the most likely routes of exposure are inhalation and eye exposure. (who.int)

Title : Guidance for inhalation exposures to particulate matter : V2 - April 2022 Corporate Authors(s) : United States. (cdc.gov)
Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome. (uchicago.edu)

To date, CIPP air monitoring studies have been unable to comprehensively characterize occupational exposures because of a narrow focus on VOC vapors and the use of nonspecific detectors. (cdc.gov)

5.1 A tiered strategy for characterization of nanoparticle properties is necessary to draw meaningful conclusions concerning dose-response relationships observed during inhalation toxicology experiments. (astm.org)
This test method describes the determination of the as administered surface area of airborne metal oxide nanoparticles in inhalation exposure chambers for inhalation toxicology studies. (astm.org)
Mohammed A. Al Mutairi, Hatim A. Al Herbish, Rakan S. Al-Ajmi, Hatim Z. Alhazmi, Reham A. Al-Dhelaan & Abdullah M. Alowaifeer (2022) Analyzing pesticides and metal(loid)s in imported tobacco to Saudi Arabia and risk assessment of inhalation exposure to certain metals, Inhalation Toxicology. (unitedchem.com)

Use site-specific data if available, or the default activity pattern data from the EPA's EFH Chapter 16 to help make appropriate determinations on indoor and outdoor activities where exposures could occur and the time spent at different places during the day (e.g., home, work, school). (cdc.gov)
Saliva from these animals can be contaminated so heavily with pathogens that a bite might not be required to cause human infection, and exposures can occur through cuts, scratches, or mucous membranes. (cdc.gov)
Loss of consciousness can occur within a minute of exposure at 300,000 ppm and within 5-10 minutes (min) of exposure at 100,000 ppm (HSDB 2004). (nationalacademies.org)
Injury to the skin may occur following exposure to concentrated gas or from being close to a release of pressurized liquid. (who.int)
Exposure to asbestos can occur when asbestos-containing material (man-made or natural) is disturbed releasing asbestos fibers into the air. (cdc.gov)
Inhalation injury due to hydrocarbons can occur as a result of either accidental or intentional exposure. (medscape.com)

Inhalation of ricin typically leads to cough and respiratory distress followed by pulmonary edema, respiratory failure, and multi-system organ dysfunction. (cdc.gov)
Recent endotoxin exposure was significantly associated with byssinosis, chronic bronchitis, and chronic cough. (nih.gov)

Inhalation is a major route of exposure that occurs when an individual breathes in polluted air which enters the respiratory tract. (wikipedia.org)

Production and use of nickel and its compounds can, however, result in additional exposures to humans and the environment. (mdpi.com)
Evidence for transdermal passage and presence in the food chain (fish) suggests potential exposure of humans during development. (researchgate.net)
chain (fish) suggests potential exposure of humans during development. (researchgate.net)
It is difficult to assess mice, which cannot repair certain In rodents, multiple studies showed the relevance to humans of rodent types of oxidative DNA damage, but that in utero exposure to arsenic via studies that use multiple agents, one not in Ogg+/+ mic e (IARC, 2012 ). (who.int)

Neurological symptoms associated with oil spill response exposures: Results from the Deepwater Horizon Oil Spill Coast Guard Cohort Study. (uchicago.edu)
Entrance through damaged skin causes similar symptoms as those seen in overexposure through inhalation. (medscape.com)
Other symptoms are similar to those of overexposure through inhalation. (medscape.com)
Long-term occupational exposure to cotton dust that contains endotoxin is associated with chronic respiratory symptoms and excessive decline in forced expiratory volume in 1 sec (FEV 1 ), but the mechanisms of endotoxin-related chronic airflow obstruction remain unclear. (nih.gov)
In the current study, we examined temporal aspects of the exposure-response relationship between airborne endotoxin exposure, longitudinal change in FEV 1 , and respiratory symptoms in a cohort of Chinese cotton textile workers. (nih.gov)
We used a generalized estimating equations approach to model FEV 1 level and respiratory symptoms as a function of past exposure (cumulative exposure up to the start of the most recent 5-year survey interval) and cumulative exposure (within the most recent interval) to endotoxins, after adjusting for other covariates. (nih.gov)
However, the long-term exposure-response relationship between endotoxin and change in lung function and respiratory symptoms is not well understood. (nih.gov)
Previous analyses of the present study population, a cohort of Chinese cotton textile workers, evaluated longitudinal change in FEV 1 and the occurrence of chronic respiratory symptoms in relation to cumulative endotoxin exposure. (nih.gov)
Whether the excessive decline in lung function and the occurrence of respiratory symptoms are influenced differently by more recent or more remote exposure to endotoxin is unknown. (nih.gov)
In the present study, we evaluated the exposure-response relationship between cumulative endotoxin exposure and longitudinal change in FEV 1 and the occurrence of respiratory symptoms in an updated follow-up of a 25-year prospective cohort study of Chinese cotton textile workers. (nih.gov)

Since the most relevant route of exposure is inhalation hazard characterization shall preferably be performed via inhalation. (europa.eu)
Identify the most important route of exposure to asbestos which leads to health effects. (cdc.gov)
The air pathway is the most important route of exposure to asbestos. (cdc.gov)
The air pathway (inhalation of contaminated air) is the most important route of exposure to asbestos and the route that most commonly leads to illness. (cdc.gov)

Exposure is commonly understood to be the concentration of the airborne pollutant in the air at the mouth and nose boundary. (wikipedia.org)
Respiratory absorption is influenced by the contaminant concentration in the air, breathing rate, and duration of exposure. (cdc.gov)
ATSDR's standard approach for evaluating inhalation exposures is to adjust the air concentration (EPC) by an appropriate EF (rather than calculate an exposure dose) depending on chronic, intermediate, or acute exposure. (cdc.gov)
The purpose of this calculation is to adjust the air concentration to account for the duration, frequency, and time of exposure. (cdc.gov)
If the target population has acute inhalation exposure to ammonia, hydrogen sulfide, chloroform, sulfur dioxide, or formaldehyde, do not adjust the EPC to a continuous 24-hr concentration because the acute inhalation Minimal Risk Level (MRL) for non-cancer effects was derived using the unadjusted study concentration. (cdc.gov)
The same is true for intermediate and chronic exposure for chloroform and formaldehyde, which have MRLs based on the unadjusted study concentration, so the non-cancer EF should be 1. (cdc.gov)
After a single experimental exposure in which four men inhaled 100 parts per million (ppm) of trichloroethylene for four hours an elimination curve showed three exponential components, that is, X=1-0005e(-16.71t)+0-449e(-1.710t)+0-255e(-0.2027t), where X is that blood concentration in mg/l and t the time in hours from 0 to 10. (bmj.com)
The estimated LCt50 (the product of concentration 50 times time that is lethal to 50% of the exposed population by inhalation) ranges from 10 mg-min/m 3 for VX to 400 mg-min/m 3 for GA. (cdc.gov)
The extent of skin injury depends on the concentration and duration of exposure. (medscape.com)
The developed model takes into account the locally varying aerosol concentration levels which the susceptible accumulate via inhalation. (aalto.fi)
The severity of effects depends on the concentration and on the duration of exposure. (who.int)

Death from intentional inhalation of hydrocarbon fumes is not uncommon and is usually due to sudden cardiac events or CNS depression. (medscape.com)

ㆍ Exposure factor is important for inhalation exposure assessment of chemicals used in household products. (e-jehs.org)
Our research goal was to reveal a correlation between reaction of leucocytes migration inhibition to formaldehyde and level of inhalation exposure to the examined chemicals. (fcrisk.ru)
Depending on study design, timing of selenium exposure during carcinogenesis, and combination with other chemicals, selenium treatment had either a protective role or increased tumor development. (dguv.de)

T he mission of the Inhalation Exposure Core is to provide a specialized scientific resource for the assessment of health impacts resulting from inhaled environmental constituents and evaluation of therapeutics for the mitigation of cardiorespiratory disease while serving as an educational resource for the technology comprising this service. (ucdavis.edu)
The Inhalation Exposure Core also supports the assessment of cardiorespiratory function and bronchoscopic collection of lung specimens for in vivo disease characterization, as well as response to clinical and preclinical therapeutics. (ucdavis.edu)
This book reviews the information necessary to address the steps in exposure assessment relevant to air pollution . (environmental-expert.com)
The main objective of the book is to contribute to the existing knowledge and practical application of modern technologies for exposure and risk assessment of chemical environmental pollution with emphasis on methodologies and the models used for environmental security. (environmental-expert.com)
The aim of this epidemiological and toxicological risk assessment of selenium and its compounds is to derive exposure riskrelationships (ERBs) if assessed to be carcinogenic or alternatively, an occupational exposure limit (AGW) based on the most sensitive endpoint, if assessed to be non-carcinogenic and ERBs cannot be derived. (dguv.de)

Inhalation is an important pathway for human exposure to contaminants that exist as atmospheric gases or are adsorbed to airborne particles or fibers. (cdc.gov)

In order to obtain information on human exposure, we conducted a monitoring study on human milk with three series of mother-child pairs (2004, 2005, 2006), with focus on cosmetic UV filters in relation to other endocrine disrupters. (researchgate.net)
They also indicate that it may be possible to reduce human exposure during critical periods such as pregnancy and lactation by transiently abstaining from use. (researchgate.net)
The most prevalent (two studies) and CD1 mice (IARC, cifically including beryllium and source of human exposure to ar- 2012 ). (who.int)

These data, in combination with time-activity profiles of residents, can be used to estimate indoor air exposures to vapor-forming contaminants (discussed below). (cdc.gov)
Despite the plethora of data on the toxic contaminants contained in tobacco smoke and their impact on health, only recently has there been recognition that exposure to long-lived tobacco smoke components in indoor environments where smoking has taken place may result in possible adverse health consequences. (springer.com)
This paper addresses the challenge of limiting exposure to long-lived tobacco components, or THS, in indoor environments. (springer.com)
We then consider other case studies of controlling indoor environmental exposures-asbestos, lead, and radon-that provide "lessons learned" for THS. (springer.com)
The Monte-Carlo simulations, along with the theory, provide clear quantitative insight to the exposure time in different public indoor environments. (aalto.fi)

It was during the 1800s that the phrase "mad as a hatter" was coined, owing to the effects of chronic mercury exposure in the hat-making industry, where the metal was used in the manufacturing process. (medscape.com)
Changes in sputum cytology, airway inflammation and oxidative stress due to chronic inhalation of biomass smoke during cooking in premenopausal rural Indian women. (uchicago.edu)

Mechanisms and Treatment of Halogen Inhalation-Induced Pulmonary and Systemic Injuries in Pregnant Mice. (uchicago.edu)
Relationship between household air pollution from biomass smoke exposure, and pulmonary dysfunction, oxidant-antioxidant imbalance and systemic inflammation in rural women and children in Nigeria. (uchicago.edu)
The asthma studies necessitated the establishment of a pulmonary function laboratory with extensive capabilities for testing nonhuman primates under the direction of a pulmonary physiologist to assess function in animals undergoing exposure. (ucdavis.edu)
Rapid absorption occurs across the large surface area of the pulmonary vascular bed, and peak blood levels are noted approximately 15-30 minutes after inhalation. (medscape.com)

The human body is exposed to pollution on a daily basis via dermal exposure and inhalation. (environmental-expert.com)

While it is unlikely that data will be available to quantitatively estimate exposures from this pathway, acknowledge this potential exposure pathway for air contaminants that can be readily absorbed through the skin. (cdc.gov)
The main occupational pathway of exposure is by inhalation. (dguv.de)
Today, with the appropriate use of personal protective equipment by those working with asbestos, dermal contact is rarely a significant exposure pathway. (cdc.gov)

The obtained results prove that inhalation formaldehyde load influences teenag-ers from industrial centers as sensitization to this substance evolves in them. (fcrisk.ru)

Asbestos that is embedded or contained in undisturbed solid materials presents a negligible risk of exposure. (cdc.gov)
The primary route of asbestos entry into the body is inhalation of air that contains asbestos fibers. (cdc.gov)
With dermal exposure, asbestos fibers may lodge in the skin. (cdc.gov)
The first four scenarios above were common until the 1970s, when the U.S. Environmental Protection Agency (EPA) began to regulate the industrial uses of asbestos and the Occupational Safety Health Administration (OSHA) developed workplace exposure standards [Seidman and Selikoff 1990]. (cdc.gov)
Asbestos levels in most water supplies are well below the EPA maximum contaminant level (MCL), so significant exposure by drinking water is uncommon. (cdc.gov)
In the past, handling asbestos could result in significant dermal contact and exposure. (cdc.gov)

Inhalation exposure to three-dimensional printer emissions stimulates acute hypertension and microvascular dysfunction. (cdc.gov)

Inhalation of fine silica particles can lead to silicosis, a serious lung disease that causes inflammation and scarring in the lungs, reducing their ability to take in oxygen. (legalmatch.com)
Additionally, we and others have reported that inhalation of xenobiotic particles in this size range is associated with an array of cardiovascular dysfunctions. (cdc.gov)

Some commonly encountered substances in occupational exposure scenarios include the following. (legalmatch.com)

In addition, in a study of CD1 beryllium compounds, cadmium senic is now drinking-water, where mice with "whole-life" exposure to and cadmium compounds, chromi- it is found primarily as the inorgan- multiple levels of sodium arsenite in um(VI) compounds, and nickel and ic forms of arsenite and arsenate. (who.int)

Identification of the pollutant uptake by the respiratory system can determine how the resulting exposure contributes to the dose. (wikipedia.org)
Following an inhalation exposure of rats to radiolabeled MDI, 79 % of the dose was excreted in feces. (europa.eu)
The applicant states that the proposed budesonide/formoterol Spiromax 80/4.5, 160/4.5, 320/9 µg per dose, inhalation powder products would replace the currently marketed medicinal products and hence the exposure of the environment to budesonide and formoterol is not likely to increase. (janusinfo.se)

This contact could lead to various health hazards or occupational exposure injuries . (legalmatch.com)
Office workers might face exposure to ergonomic hazards. (legalmatch.com)
This is the maximum protection for workers in danger of exposure to unknown chemical hazards or levels above the IDLH or greater than the AEGL-2. (cdc.gov)

Dermal exposure to some air contaminants could result in absorption through the skin. (cdc.gov)

Health effects of exposure to the substance have been investigated but no serious effects have been found so far. (ilo.org)
The greatest value of danger coefficient in terms of exposure to this substance was equal to 1.76. (fcrisk.ru)
The substance can be absorbed into the body by inhalation and through the skin also as a vapour. (inchem.org)
Sniffing, the least potent delivery method, is the inhalation of the volatile substance through the nostrils (ie, sniffing glue). (medscape.com)

The CPWR Toolbox Talk on Preventing Exposure to Silica Dust in Enclosed Cabs addresses the risks associated with breathing in silica dust and silicosi. (elcosh.org)

Bagging involves repeated deep inhalations from a plastic or paper bag filled with a particular hydrocarbon such as spray paint or another propellant. (medscape.com)

Dermatitis may result from repeated exposure to chloropicrin. (medscape.com)

The Inhalation Exposure Core encompasses state-of-the-art facilities for the short- and long-term generation of precisely controlled atmospheres and delivery to both in vitro and in vivo laboratory animal models under the guidance of CNPRC Core and Affiliate Scientists. (ucdavis.edu)
The subcommittee considered all of that information in its evaluation of the Navy's current and proposed 1-hour (h), 24-h, and 90-day exposure guidance levels for CO 2 . (nationalacademies.org)

The CPWR Toolbox Talk on Preventing Exposure to Nano-Enabled Construction Materials identifies how to reduce exposure to the dust generated when cutti. (elcosh.org)
This CPWR Hazard Alert on Working in enclosed cabs provides information on protecting workers from silica dust, how to minimize exposures and the dang. (elcosh.org)

Research on active smoking and secondhand smoke exposure has led to policy changes to protect individuals from the adverse health impacts of tobacco smoke. (springer.com)
Nearly three decades have also passed since the US Surgeon General and other scientific authorities concluded that exposure to secondhand tobacco smoke (SHS) causes disease in nonsmokers, including lung cancer in adults [ 2 - 4 ]. (springer.com)

Characteristics and Prevalence of Domestic and Occupational Inhalational Exposures Across Interstitial Lung Diseases. (uchicago.edu)

Inhalation is most commonly achieved by sniffing, huffing, or bagging. (medscape.com)

At the time of experiments, animals exposed to 3DPE inhalation presented with a mean arterial pressure of 125 +/- 4 mm Hg, and this was significantly higher than that for the sham-control group (94 +/- 3 mm Hg). (cdc.gov)
These alterations in peripheral microvascular resistance and reactivity are consistent with elevations in arterial pressure that follow 3DPE inhalation. (cdc.gov)

Deliberate inhalation of volatile hydrocarbons for their mood-altering effects is popular among adolescents. (medscape.com)

Sprague-Dawley rats were exposed to 3DPE aerosols via nose-only exposure for approximately 3 h. (cdc.gov)

Selected chemical and physical properties, toxicokinetic and mechanistic data, and inhalation exposure levels from the National Research Council (NRC) and other agencies are also presented. (nationalacademies.org)
For reactive substances like diisocyanates significant toxicokinetic differences can be demonstrated, e.g. with respect to primary reaction products at the portal of entry (oral, dermal, inhalation). (europa.eu)
While no oral toxicokinetic studies of oral MDI exposure are available, the behavior of MDI substances in the stomach following gavage is expected to be similar to another aromatic diisocyanate. (europa.eu)

Measuring tandem-repeat hypomethylation in easy-to-obtain blood specimens might identify individuals with biological effects and potential cancer risk from PM exposure. (nih.gov)
Repeated or prolonged inhalation may cause effects on the lungs. (ilo.org)
The timing of exposure is not the only potential influence on the long-term effects of endotoxin on changes in lung function. (nih.gov)

The adjustment enables comparisons to duration-related inhalation non-cancer health guidelines and inhalation cancer risks . (cdc.gov)

This section describes how health assessors can estimate inhalation exposures. (cdc.gov)
Health assessors can use PHAST (see PHAST text box below) to help evaluate inhalation exposures. (cdc.gov)
Little is known about CIPP worker exposures and health risks. (cdc.gov)
See below for information on the October 5th free webinar "Public Health Implications and Occupational Exposures during Water Pipe Repair Activities" (to view webinar, click here ). (cdc.gov)
help reduce exposures to talc from certain natural health products and non-prescription drugs, which may be inhaled or which could come in contact with the female genital area by modifying the existing entries of the Natural Health Products Ingredients Database and applicable monographs. (canada.ca)
These scientific conclusions have led to a broad range of policy actions and public health programs in the USA and worldwide aimed at reducing smoking prevalence and exposure to SHS in public places. (springer.com)
Urinary cotinine was a useful biomarker for identifying exposure to SHS, with respect to the influence of demographic, health-related, and smoking-related factors. (ophrp.org)
Thus, the adverse impacts of SHS on bystanders' health are mainly due to the inhalation of large amounts of side stream smoke [ 6 ]. (ophrp.org)
The biggest concern when using household chemical products is the health risk from inhalation exposure. (e-jehs.org)
Inhalant abuse, the deliberate inhalation of hydrocarbons as a form of recreational drug use, has become a significant health issue affecting children. (medscape.com)

Pleuropulmonary nocardiosis presumably arises from inhalation exposure. (medscape.com)

Risk factors for asthma include a family history of allergic disease, the presence of allergen-specific immunoglobulin E (IgE), viral respiratory illnesses , exposure to aeroallergens , cigarette smoke, obesity , and lower socioeconomic status. (medscape.com)

Past exposure to endotoxin was associated with reduced FEV 1 level among retired cotton workers. (nih.gov)

Organized lymphatic tissue (BALT) in lungs of rhesus monkeys after air pollutant exposure. (ucdavis.edu)

Immigrant and refugee children are at much greater risk for lead poisoning than children born in the United States because of diet and other exposure risks before arriving in the United States. (medlineplus.gov)

[ 7 ] Using a cross-sectional design, the authors compared children living on farms to those in a reference group with respect to the prevalence of asthma and to the diversity of microbial exposure. (medscape.com)

Anatomy7

Organisms5

Diseases12

Chemicals and Drugs50

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Phenomena and Processes19

Disciplines and Occupations1

Technology, Industry, Agriculture9

Named Groups1

Health Care8

Ingestion12

Toxicity4

Routes of Exposure1

Particulate matter2

Vapors1

Toxicology3

Occur6

Cough2

Respiratory tract1

Humans4

Symptoms10

Route of exposure4

Concentration11

Fumes1

Chemicals3

Assessment5

Airborne1

Human exposure3

Indoor5

Chronic2

Pulmonary4

Pollution1

Pathway3

Formaldehyde1

Asbestos6

Acute1

Particles2

Scenarios include1

Beryllium1

Dose3

Hazards3

Contaminants1

Substance4

Risks Associated1

Hydrocarbon1

Dermatitis1

Guidance2

Dust2

Tobacco smoke2

Inhalational1

Commonly1

Arterial2

Volatile1

Rats1

Toxicokinetic3

Effects3

Duration1

Health10

Arises1

Illnesses1

Workers1

Lungs1

Poisoning1

Prevalence1