• Chlorine is a gas at room temperature, making ingestion an unlikely route of exposure. (cdc.gov)
  • Ingestion is the most important exposure route. (cdc.gov)
  • Ethylene glycol is rapidly absorbed following ingestion, which is the predominant route of exposure. (cdc.gov)
  • The possible routes of BPA exposure are by ingestion or through absorption into the skin. (sgs.com)
  • Again, a low order of systemic toxicity is expected, if absorption via the dermal route of exposure occurs. (europa.eu)
  • Dermal absorption is negligible and does not contribute significantly to systemic toxicity. (cdc.gov)
  • Significant skin absorption or ingestion is unlikely. (cdc.gov)
  • BetterYou is currently working in tandem with Northwick Park Hospital on the first-ever absorption trial to determine if spraying magnesium on the skin can remedy low serum magnesium levels in individuals who have small bowel stoma. (worldhealth.net)
  • absorption through non-intact skin or via a solvent carrier), or ocular contact. (cdc.gov)
  • 7. If the listing for an agent in the Ontario Table or in the ACGIH Table includes the notation "Skin" and the agent is present at the workplace, the employer shall take all measures reasonably necessary in the circumstances to protect workers from skin absorption of the agent. (ontario.ca)
  • Ingestion of ethylene glycol leads to systemic toxicity beginning with CNS effects, followed by cardiopulmonary effects, and finally renal failure. (cdc.gov)
  • Amatoxin toxicity is caused by the ingestion of mushrooms containing these cyclopepeptide toxins, especially Amanita phalloides (see the image below), commonly known as the death cap. (medscape.com)
  • C. Toxicity may be delayed after ingestion of sustained release products. (antidepressantsfacts.com)
  • If absorption of the intact parental compound or the respective metabolites occurs, it is predicted to cause a low order of systemic toxicity. (europa.eu)
  • Our data suggest that the main reason addicts prefer nasal to oral cocaine dosing is faster absorption, enhancing the subjective effects rather than higher bioavailability. (erowid.org)
  • People prefer to use the sublingual method of Ingestion for faster absorption. (allpeers.com)
  • Ingestion is the process by which the food is taken inside through mouth and broken down by teeth and initial digestion takes place in the mouth by saliva. (tutorialspoint.com)
  • ANP infusion did not alter Na absorption at the esophagus, but it profoundly reduced the absorption at the intestine. (bioone.org)
  • Together with our previous finding that ANP does not alter renal Na excretion, we propose that ANP reduces plasma Na concentration in SW eels by inhibiting drinking and subsequent absorption of Na by the intestine. (bioone.org)
  • When iron levels are low (as in iron deficiency), hepcidin promotes iron absorption from the small intestine. (medscape.com)
  • Ingestion can cause irritation to the gastrointestinal mucosa and can be complicated by pulmonary aspiration, resulting in chemical pneumonitis. (cdc.gov)
  • however, persons with pre-existing tissue irritation or damage who are exposed to ricin may sustain further injury and greater absorption of ricin toxin. (cdc.gov)
  • B. Tremors and seizures are the most likely effects in acute overdose, occurring within 1 to 4 hours following ingestion, with the exception of sustained-release preparations, which have been reported to result in delayed seizures. (antidepressantsfacts.com)
  • The aim of this study was to estimate and compare cocaine input into the systemic circulation after oral and nasal dosing, and to determine the relevance of local absorption through the nasal mucosa. (erowid.org)
  • Symptoms of intoxication by ingestion of gasoline can range from vomiting, vertigo, drowsiness and confusion to loss of consciousness, convulsions, hemorrhaging of the lungs and internal organs, and death due to circulatory failure. (cdc.gov)
  • Phalloidin has limited gastrointestinal (GI) absorption, and symptoms improve within hours of supportive care. (medscape.com)
  • Absorption is the process in which cells use the energy from the digested food and helps in building tissues in our body. (tutorialspoint.com)
  • The available information indicates that the intact parent compound is not assumed to distribute throughout the body due to limited absorption. (europa.eu)
  • Hereditary HFE hemochromatosis accounts for most cases of excess body iron that result from increased iron absorption. (medscape.com)
  • The pharmacokinetic interactions in absorption of tetracyclines likely to be clinically significant in cases where the infecting pathogens are moderately resistant to tetracyclines and relatively high serum concentrations are needed for proper bacteriostasis. (nih.gov)
  • Ingestion and mastication of three to eight castor beans is the estimated fatal dose in adults. (cdc.gov)
  • The clinical manifestations of an A phalloides ingestion are caused by the cyclopeptide phallotoxins and amatoxins. (medscape.com)
  • Upon ingestion, it is rapidly absorbed (within 1 to 4 hours). (cdc.gov)
  • Phalloidin, a cyclic heptapeptide, causes gastroenteritislike effects 6-12 hours after initial ingestion. (medscape.com)
  • The first stage is preceded by a characteristic latent period that lasts for 6-12 hours following ingestion. (medscape.com)
  • An interval of 3 hours between the ingestion of tetracyclines and cations prevents the interaction. (nih.gov)
  • Ingestion of ethylene glycol produces CNS depression which may be accompanied by nausea, vomiting, and abdominal cramps. (cdc.gov)
  • After oral dosing, cocaine input into systemic circulation increased slowly and peaked around 45 min after ingestion. (erowid.org)
  • Based on available data, absorption after oral ingestion is predicted to be very low. (europa.eu)
  • After nasal dosing, drug input was substantial even during the first minute and showed two peaks at 10 min and 45 min after ingestion. (erowid.org)
  • Milk and other dairy products, antacids containing polyvalent cations, as well as various iron salts ingested simultaneously with tetracycline derivatives, might interfere with their absorption by 50 to 90% or even more. (nih.gov)
  • Hepcidin, which is produced in the liver and to a smaller extent in adipocytes and macrophages, is a key regulator of iron absorption. (medscape.com)
  • [ 7 , 8 ] Hepcidin acts by binding to the iron exporter ferroportin, blocking the transport and release of iron, leading to retention of iron within enterocytes and reduced iron absorption. (medscape.com)
  • Type 1 hemochromatosis results from reduced hepcidin expression and increased iron absorption, exceeding the capacity of transferrin to transport iron. (medscape.com)
  • Many antifreeze products also contain yellow-green fluorescent dyes and a bitter taste to reduce the chances of accidental ingestion. (cdc.gov)