Informative genetic markers. Medical search. Frequent questions

2000 ). Traditionally, upon the advent of Polymerase Chain Reaction (PCR) technology, genetic variation within wild populations used to be determined either employing a handful of neutral microsatellite markers or assessing mitochondrial DNA sequences (Chapman et al. (nature.com)
Rapid genetic analysis of families with polycystic kidney disease 1 by means of a microsatellite marker. (ox.ac.uk)
We identified two microsatellite polymorphisms that lie closer to the PKD1 locus than any previously described highly variable marker. (ox.ac.uk)
The aim of the present study was to estimate the genetic variability of Muzhake goat breed using microsatellite markers. (cipav.org.co)
The genomic DNA from 30 unrelated individuals, was analyzed by typing 30 microsatellite markers. (cipav.org.co)
Genetic diversity of Albanian local goat breeds was estimated previously using microsatellite markers (Hoda et al 2011). (cipav.org.co)
A panel of 30 microsatellite markers as suggested by FAOs MoDAD programme, was used for genetic characterization of Muzhake goat, according to the methodology explained in detail by Canon et al 2006). (cipav.org.co)
Observed heterozygosity (Ho), expected heterozygosity (He) were estimated for 30 microsatellite markers using the same software. (cipav.org.co)
Ewens-Watterson test was performed to test the neutrality for microsatellite markers, using the algorithm by Manly (2007) using 1000 simulated samples and implemented in Popgene software package (Yeh et al 1999). (cipav.org.co)
There were identified 240 alleles in the whole population for 30 microsatellite markers. (cipav.org.co)
Abstract Ten polymorphic microsatellite markers are described for the Mediterranean bath sponge Spongia officinalis. (researchgate.net)
A battery of 14 microsatellite markers was used to carry out parentage tests of 256 progeny individuals including two independent samples of selected trees and one control unselected sample, all derived from 6-year-old forest stands in eastern Brazil. (springer.com)
Brondani RPV, Brondani C, Tarchini R, Grattapaglia D (1998) Development and mapping of microsatellite based markers in Eucalyptus. (springer.com)
Genetic diversity and relatedness between Canindé and British Alpine goat breeds in Northeastern Brazil accessed by microsatellite markers. (geneticsmr.com)
The aim of this study was to access the genetic diversity and relatedness between Canindé and British Alpine goat breeds in the States of Piauí and Ceará using microsatellite markers. (geneticsmr.com)
The microsatellite markers resulted in a total number of 145 alleles, with an average of 8.5 alleles per locus. (geneticsmr.com)
The exotic British Alpine breed and the naturalized Brazilian Canindé breed were clearly differentiated by the microsatellite markers, indicating that these two breeds have distant genetic identities, despite the phenotypic similarity. (geneticsmr.com)
This microsatellite appears to be an informative DNA marker for genetic linkage analysis in goats. (unica.it)
To assess if the behavioral difference between the family and kenneled dogs could be due to genetic divergence of these two populations and/or to lower genetic diversity of the kenneled dogs, we analyzed their genetic structure using 11 microsatellite markers. (frontiersin.org)
We used next generation sequencing (Roche 454 pyrosequencing) to identify microsatellite markers from the genomic DNA of M. gilvus. (eurekamag.com)
This study also has effectively demonstrated the use of 454 pyrosequencing for the rapid development of informative microsatellite markers from a termite genome. (eurekamag.com)
We propose a nomenclature for microsatellite tagged LT/TNF alleles based on their size and variability, which could also be extended to include RFLP and other not yet identified polymorphic markers. (ox.ac.uk)
In this study, we developed microsatellite markers for nine endangered amphibian species endemic to Ryukyu Islands in Japan. (nii.ac.jp)

Identification of genetic structure within wildlife populations have implications in their conservation and management. (nature.com)
Genetic markers are employed in genealogical DNA testing for genetic genealogy to determine genetic distance between individuals or populations. (wikipedia.org)
Impact of cross-ancestry genetic architecture on GWASs in admixed populations. (amedeo.com)
Our scientists have collaborated with leading researchers at academic institutions around the globe, including the University of Utah, on research projects that investigate migration patterns and how genetic variation is shared among populations. (ancestry.com.au)
This genetic marker was also useful in identifying a separate Townsville haplotype population and another population on Thursday Island in the Torres Strait that is genetically distant to the mainland populations. (health.gov.au)
Identifying differences in mosquito strains or populations requires a DNA-based genetic marker that will be informative, will deliver an unambiguous result, will be relatively straightforward to use, and ideally, be useful in later studies of evolution or population genetics. (health.gov.au)
In a species whose populations in the eastern Mediterranean basin have been substantially declined due to recurring mass mortality incidents and intensive harvesting, these markers are expected to assist studies of genetic structure and differentiation between populations. (researchgate.net)
Comparative analysis of shell color variety and genetic structure among five high-quality freshwater pearl mussel populations. (geneticsmr.com)
RAPID-COMMUNICATION Genetic diversity and differentiation in natural populations of Arapaima gigas from lower Amazon revealed by microsatellites. (geneticsmr.com)
We found no significant difference between the populations in their genetic diversity (i.e., heterozygosity, level of inbreeding), nor any evidence that the family and kenneled populations originated from different genetic pools. (frontiersin.org)
The creation of ultra-high density genetic maps using large populations of advanced recombinant inbred lines (RILs) is an efficient way to identify QTL for complex agronomic traits. (biomedcentral.com)
Microsatellites are currently the most practical and informative molecular maker for measuring genetic variation within populations. (nii.ac.jp)
Studying the genetics of the pathogens in terms of virulence to better understand the pathogen populations and provide informative advice to plant breeders. (gc.ca)
Ixodes ricinus ticks ( 11 ) and is carried by a large variety of ize genetic variations of natural populations of a bacterial hosts, including birds and small- to medium-sized mam- pathogen ( 1 , 2 ). (cdc.gov)
Misconceptions about the use of genetic tests in populations. (who.int)

We describe genetic variants encoded on chromosome 10 that correlate with RAN, RAS, reading, and volume of a reading center in the brain. (bmj.com)
The location of these variants on the chromosome suggest they could be informative markers for genetic factors that modify the instructions for turning on and off a gene called renelase, which has not been previously linked to reading. (bmj.com)
This is exemplified in "BRCAness" - a gene expression signature that suggests a deficient homologous recombination (HR) pathway, even in the absence of deleterious genetic variants in the BRCA1/2 genes. (nature.com)
A notable challenge exists when dealing with the high dimensionality of the data sets, as thousands of genes or millions of genetic variants are collected on a relatively small number of subjects. (escholarship.org)
This can be ameliorated by filtering genetic variants, exploiting or accounting for correlations between variants, jointly testing variants, and by incorporating informative priors. (umanitoba.ca)
Jung SY, Papp JC, Sobel EM, Pellegrini M, Yu H. Genetic variants of glucose metabolism and exposure to smoking in African American breast cancer. . (ucla.edu)
Synergistic Effects of Genetic Variants of Glucose Homeostasis and Lifelong Exposures to Cigarette Smoking, Female Hormones, and Dietary Fat Intake on Primary Colorectal Cancer Development in African and Hispanic/Latino American Women. (ucla.edu)
Genetic Variants in Metabolic Signaling Pathways and Their Interaction with Lifestyle Factors on Breast Cancer Risk: A Random Survival Forest Analysis. (ucla.edu)
Jung SY, Ho G, Rohan T, Strickler H, Bea J, Papp J, Sobel E, Zhang ZF, Crandall C. Interaction of insulin-like growth factor-I and insulin resistance-related genetic variants with lifestyle factors on postmenopausal breast cancer risk. . (ucla.edu)
This raises the need to filter, or prioritize, or jointly test genetic variants. (biomedcentral.com)
Recently, multiple annotation tools have become available using several databases and algorithms that predict functional effects of genetic variants. (biomedcentral.com)
This article discusses approaches that filtered or prioritized genetic variants, regions, or genes. (biomedcentral.com)
Many researchers filter genetic variants. (biomedcentral.com)
Thus, the behavior difference between the groups more likely reflects a G × E interaction, that is, the influence of specific genetic variants manifesting under specific environmental conditions (kennel life). (frontiersin.org)
A Boolean Algebra for Genetic Variants. (cdc.gov)

Genetic markers have also been used to measure the genomic response to selection in livestock. (wikipedia.org)
Disease Resistance in Crop Plants : Molecular, Genetic and Genomic Perspectives. (wikipedia.org)
The discovery of genetic or genomic markers plays a central role in the development of personalized medicine. (escholarship.org)
Chromosomal localisation, genomic regions corresponding to functional domains and the genetic variability of microsatellites in the 3' untranslated region (3'-UTR) of this gene were investigated in 427 goats (Capra hircus) of six breeds. (unica.it)
To localize and define additional polymorphic markers, we probed the collection of genomic clones with synthetic tandemly repeated dinucleotides, corresponding to the sequences known as microsatellites. (ox.ac.uk)
Four ospC clonal complexes dence of genetic endemism, recent migration events, and (A, B, I, and K groups) were found to be more likely than recombinant genomic types. (cdc.gov)

This prompted the development of gene markers which could identify genetic characteristics that are not readily observable in organisms (such as protein variation). (wikipedia.org)
Jaccard's coefficient of similarity varied from 0.64 to 0.89, indicating much genetic variation in chrysanthemums. (ashs.org)
is an exotic mosquito that probably arrived in Australia during the mid-19th century, 10 a rapidly evolving genetic marker would be required to identify population variation within this species. (health.gov.au)
Plant architecture attributes, such as plant height, ear height, and internode number, have played an important role in the historical increases in grain yield, lodging resistance, and biomass in maize ( Zea mays L . ). Analyzing the genetic basis of variation in plant architecture using high density QTL mapping will be of benefit for the breeding of maize for many traits. (biomedcentral.com)
We tested for a relationship between genetic variation in TPH2 and risk for BPAD and SA in a large family sample. (johnshopkins.edu)
Further studies are needed to uncover the functional genetic variation that accounts for the observed associations. (johnshopkins.edu)

Commonly these markers are individual genetic changes, such as driver mutations affecting oncogenes or tumor suppressor genes, or copy-number alterations thereof. (nature.com)
For microarray gene expression data, we first summarize solutions in dealing with 'large p, small n' problems, and then propose an integrative Bayesian variable selection (iBVS) framework for simultaneously identifying causal or marker genes and regulatory pathways. (escholarship.org)
We used the ESTminer suite of programs to identify potential soybean gene transcripts from a single genetic background allowing us to observe functional classifications between gene families as well as structural differences between genes and gene paralogs within families. (biomedcentral.com)
Indeed, power improved when gene expression data for FDR-controlled informative weighting of association test p values of genes was used. (umanitoba.ca)
Transposable elements can be considered as a source of raw material for primitive genomes, tools of genetic innovation, and ancestors of modern genes (e.g., ncRNA) [ 15 ]. (biomedcentral.com)
Early stages of B-cell differentiation can be identified by the status of the immunoglobulin genes and by the cell surface markers CD34, CD19, and surface immunoglobulin (sIg). (medscape.com)

A genetic marker may be a short DNA sequence, such as a sequence surrounding a single base-pair change (single nucleotide polymorphism, SNP), or a long one, like minisatellites. (wikipedia.org)
Amplified fragment length polymorphism (AFLP) markers were used to detect the relationships among 12 wild accessions and 62 groundcover chrysanthemum cultivars. (ashs.org)
In the present study, the reverse transcription domains of long terminal repeat retrotransposons were cloned from rhododendrons and used to develop inter-retrotransposon amplified polymorphism (IRAP) marker system. (preprints.org)
Previously, a low degree of genetic polymorphism at the human TNF locus has been reported, mostly bi-allelic RFLP. (ox.ac.uk)
Therefore, we describe thus far the most informative level of DNA sequence polymorphism in this part of human MHC. (ox.ac.uk)
Mapping of the oat crown rust resistance gene PC39 relative to single nucleotide polymorphism markers. (gc.ca)

Chrysanthemums have beautiful flowers with high ornamental value and rich genetic diversity. (ashs.org)
Molecular technology has been widely used in analyzing genetic relationships and diversity. (ashs.org)
In addition to the Ancestry Human Diversity Project, we have worked with the researchers at the National Marrow Donor Program® (NMDP)/Be the Match® to evaluate whether genetic ethnicity correlates with self-reported ethnicity in a group of stem-cell transplant donor-recipient pairs. (ancestry.com.au)
Based on Genetic Analysis Workshop (GAW) 19 data, this article discusses diversity and usefulness of functional variant scores provided, for example, by PolyPhen2, SIFT, or RegulomeDB annotations. (umanitoba.ca)
Molecular marker systems have the potentials to elucidate genetic diversity as well as to assess the genetic fidelity in rhododendrons. (preprints.org)
The available evidences revealed the distinct properties of IRAP and ISSR markers in the rhododendron-associated applications, and highlighted the availability of highly informative ISSR and IRAP markers in the genetic diversity evaluation and the genetic fidelity assessment of rhododendrons, which may facilitate the preservation and genetic breeding in rhododendron plants. (preprints.org)
Transposable elements (TE) are important components of livestock and poultry genomes, contributing to their genetic diversity, chromatin states, gene regulatory networks, and complex traits of economic value. (biomedcentral.com)
Characterization of maize genotypes for genetic diversity on the basis of inter simple sequence repeats. (geneticsmr.com)
Genetic diversity of represents the evolutionary history of species and the essential evolutionary potential to respond to changing environments especially for endangered species. (nii.ac.jp)

Such ancestry informative markers (AIMs), have rarely been developed for endangered species such as tigers utilizing single nucleotide polymorphisms (SNPs). (nature.com)
Unsupervised discovery of ancestry-informative markers and genetic admixture proportions in biobank-scale datasets. (amedeo.com)
DNAPrint(R)'s EuroDNA(TM) 2.0 clarifies European sub-ancestry by using 1,349 European Ancestry Informative Markers (AIMs). (thegeneticgenealogist.com)
Argentine population genetic structure was examined using a set of 78 ancestry informative markers (AIMs) to assess the contributions of European, Amerindian, and African ancestry in 94 individuals members of this population. (blogspot.com)

A prerequisite to fine mapping and marker assited selection (MAS) of quantitative trait loci (QTL) is the development of a genetic map with a high density of informative markers. (usda.gov)
The aims of quantitative trait loci detection is the potential use of these molecular markers to increase accuracy in predicting the genetic merit of breeding and its implementation in animal breeding schemes through marker-assisted selection. (cambridge.org)
Subsequently, 198 polymorphic loci were generated from the IRAP and inter-simple sequence repeat (ISSR) markers, of which 119 were derived from the IRAP markers. (preprints.org)
It was justified that in rhododendrons, IRAP markers were superior to the ISSRs in some polymorphic parameters such as the average number of polymorphic loci (14.88 versus 13.17). (preprints.org)
The polymorphic information content showed that all loci were highly informative with an overall mean of 0.757. (geneticsmr.com)
The genetic homogeneity of ospC -A isolates was confi rmed agent, Borrelia burgdorferi , a spirochete that parasitizes by sequences at 6 additional chromosomal housekeeping vertebrates, is transmitted by hard-bodied ticks through- loci ( gap, alr, glpA, xylB, ackA, and tgt ). (cdc.gov)

A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species. (wikipedia.org)
For many years, gene mapping was limited to identifying organisms by traditional phenotypes markers. (wikipedia.org)
Genetic markers can be used to study the relationship between an inherited disease and its genetic cause (for example, a particular mutation of a gene that results in a defective protein). (wikipedia.org)
This property enables the use of a marker, which can then be used to determine the precise inheritance pattern of the gene that has not yet been exactly localized. (wikipedia.org)
Marker gene Molecular marker DNA marking Eukaryotic chromosome fine structure Repeated sequence (DNA) Benjamin A. Pierce (2013-12-27). (wikipedia.org)
Dissecting the high-resolution genetic architecture of complex phenotypes by accurately estimating gene-based conditional heritability. (amedeo.com)
these are as numerous as associations with established genetic markers such as driver gene alterations. (nature.com)
Many EST libraries were constructed from RNA extracted from various genetic backgrounds, thus gene identification from these sources is complicated by the existence of both gene and allele sequence differences. (biomedcentral.com)
For example, some people of European genetic ancestry may carry two copies of the Rhesus blood group gene, RHD, while some may have just one and others none at all. (jove.com)
Genetic linkage analysis in PKD1 families suggests that both of the markers lie proximal to the disease gene, closer than existing flanking markers. (ox.ac.uk)
Identification of a locus which shows no genetic recombination with the autosomal dominant polycystic kidney disease gene on chromosome 16. (ox.ac.uk)
2006) it would be good if that future epidemiological studies of relationships between lead exposures and cancer should include evaluation of genetic susceptibility factors, such as the ALAD gene. (who.int)

Abstract High-density genetic marker data, especially sequence data, imply an immense multiple testing burden. (umanitoba.ca)

The set of used markers was highly informative. (cipav.org.co)

The presence of different alleles due to a distorted segregation at the genetic markers is indicative of the difference between selected and non-selected livestock. (wikipedia.org)
Exclusion was declared only when the obligatory paternal allele in the progeny tree was not present in the alleged parent tree for at least four independent markers to avoid false exclusions due to mutation or null alleles. (springer.com)
A search for the putative disease-associated TNF/LT alleles depends on the informative genetic markers at the TNF locus. (ox.ac.uk)

Accurately inferring population genetic structure requires whole-genome data across the geographical range of the species, which can be resource-intensive. (nature.com)
A cheaper strategy is to employ a subset of markers that can efficiently recapitulate the population genetic structure inferred by the whole genome data. (nature.com)
These 49 SNPs were sufficient to recapitulate the population genetic structure obtained from the whole genome data. (nature.com)
2020 ). Unravelling population structure involves the use of multiple markers from across the genome (Pritchard et al. (nature.com)
2009 ). With the advancement in next-generation sequencing (NGS) techniques several thousand to millions of markers across the genome have become available for population genetic analysis, even for non-model organisms (Khan and Tyagi 2021 ). (nature.com)
Sequencing of Restriction site-associated DNA (RAD) markers (RADseq) has made it increasingly possible to perform NGS without having a reference genome in hand (Catchen et al. (nature.com)
2019 ). Consequently, resolving the population structure of most wild and endangered fauna with genome-wide SNP markers has been challenging. (nature.com)
In this review we define the field of occupational and environmental health (OEH) research as the study of interactions between the following domains: environment (the exposome), 4 individual (genetic) susceptibility (the (epi)genome), and biological outcomes (the responsome) 5 ( figure 1 ). (bmj.com)
A genome examination using 85 informative molecular markers was conducted. (cambridge.org)
Microsatellites are markers of choice since they are simple to analyze, highly abundant and highly distributed in the genome. (cipav.org.co)
Our results demonstrated a relatively high degree of collinearity between the genetic map and the B73 reference genome. (biomedcentral.com)

One of these, CMM65b (D16S84), shows no recombination with PKD1 in 201 informative meioses. (ox.ac.uk)
A high-density genetic map was constructed using 4183 bin markers (100-Kb intervals with no recombination events). (biomedcentral.com)

Both CNV and SNPs are immensely valuable in genetic screening studies and kinship analysis. (jove.com)
Moreover, the current study provides a set of informative SNPs that can be used to ascertain or control for this potentially hidden stratification. (blogspot.com)

The first genetic linkage map of maize was constructed in 1986 based on restriction fragment length polymorphisms (RFLP) in the F 2 mapping population of a cross between H427 and 761 [ 7 ]. (biomedcentral.com)

Genetic variability and divergence rates were tested between stem (paired) and loop (unpaired) regions of secondary structure. (unboundmedicine.com)
Assessment of genetic variability and genetic characterization of a breed is very important step for undertaking conservation measurements. (cipav.org.co)
On the other hand, dogs bred and kept solely for breeding or research purposes ("kenneled dogs") are kept and handled under standardized conditions, and are usually of the same breed, thus the effects of environmental and breed-specific genetic variability on their individual behavioral variability is small. (frontiersin.org)

Restriction endonuclease markers were developed to distinguish among the species at all life history stages, allowing rapid identification in areas of sympatric distribution. (unboundmedicine.com)

Species accumulation curves indicated that, after controlling for sampling effort, melissopalynological characterization provides similar or higher species richness estimates than either marker. (biomedcentral.com)
Genetic characterization of native breeds is very important in conservation strategy designing. (cipav.org.co)

Almost 2,000 years ago a Greek physician was first to identify slender jaws as a marker for TB susceptibility, and he turned out to be right! (neurosciencenews.com)
The low body weight of this slender physique is still today recognized by the Centers for Disease Control and Prevention as a marker for TB susceptibility. (neurosciencenews.com)

Uniparental markers (on mitochondrial or Y chromosomal DNA) are studied for assessing maternal or paternal lineages. (wikipedia.org)
Chromosome-specific libraries provide a means to isolate genetic markers from specific chromosomal regions. (usda.gov)

Genetics: Genetic variations contribute to individual differences in personality traits that impact social behavior. (faceovl.com)
Moreover, exploring the genetic background of their higher resilience could also help to better understand the genetics behind stress- and fear-related behaviors. (frontiersin.org)
These markers will open new avenues for the study of phylogeography and population genetics of this fungus-growing termite. (eurekamag.com)

Assessing the population genetic structure of wild species is important for their management (Wultsch et al. (nature.com)
AFLP technology could be very efficient for discriminating species of chrysanthemum and its related genera and reconstruct their genetic relatedness. (ashs.org)
Further, IRAP markers demonstrated more efficiency in genetic fidelity detection of in vitro R. bailiens, an endangered species just recorded in Guizhzhou Province, China. (preprints.org)
Cross taxa amplification was successful across a panel of four related termite species and four multiplex groups were designed for future population genetic studies. (eurekamag.com)
By using these markers, fine scale population structures and genetic diversities of these species were revealed. (nii.ac.jp)
Different clonal complexes may prefer molecular markers provides a more robust inference on different host species ( 9 ). (cdc.gov)

It means that these individuals have to rely on non-genetic records to prove their ancestors Native heritage - or they need to test a different line - like the descendants of the mother, through all females, for example, for mitochondrial DNA. (dna-explained.com)

The coefficient of genetic differentiation value (G(ST)) was 0.084. (unica.it)

Although the USDA reference linkage map for bovine chromosome 6 (BTA6) contained more than 50 DNA markers and numerous research groups had used this map to identify QTL, inter-marker resolution has not been sufficient to better resolve these QTL. (usda.gov)
The total genetic distance covered by the linkage map was 1545.65 cM and the average distance between adjacent markers was 0.37 cM with a physical distance of about 0.51 Mb. (biomedcentral.com)

Selected 16S rRNA and ankA PCR amplicons were sequenced with an ABI 310 Genetic Analyzer (Applied Biosystems, Foster City, CA, USA) and analyzed by using BLASTn ( www.ncbi.nlm.nih.gov.blast ) analysis of GenBank sequences. (cdc.gov)
extracting and curating sequences from taxonomically-informative genetic markers. (osu.edu)

We used a chromosome specific library to systematically increase DNA marker density for BTA6. (usda.gov)
The nearly two-fold improvement in informative marker density of BTA6 provides a genetic map that will enhance fine mapping of QTL on this chromosome. (usda.gov)

Yesterday was another big day for genetic genealogy, with two major announcements. (thegeneticgenealogist.com)
On March 14th and 15th of this year, Family Tree DNA hosted the 5th Annual Conference on Genetic Genealogy. (thegeneticgenealogist.com)

Results: Single-marker analysis failed to detect significant genetic association with BPAD or SA, but the number of informative families was small. (johnshopkins.edu)

PCR products were run on a 3500 Genetic Analyzer (Thermo Fischer, USA). (intechopen.com)

Among all accessions, genetic relationship was the most relevant factor in AFLP-marker clustering, whereas petal type was also informative. (ashs.org)

With the availability of very dense genetic marker data sets, such as sequence data, even large association studies can become underpowered. (biomedcentral.com)

The most informative biomarkers for predicting major cardiovascular events were BNP and the urinary albumin-to-creatinine ratio. (medscape.com)

Autosomal markers are used for all ancestry. (wikipedia.org)

GBS has been a powerful tool for SNP discovery and high-density genetic map construction. (biomedcentral.com)

To meet the growing demand for safe animal protein, genetic improvement of livestock must be done sustainably while minimizing negative environmental impacts. (biomedcentral.com)

Presymptomatic diagnosis of polycystic kidney disease 1 (PKD1) is possible by genetic linkage analysis with markers from both sides of the disease locus. (ox.ac.uk)
The new markers and physical map described here provide an improved framework for attempts to clone the PKD1 region and to identify polycystic kidney disease mutations. (ox.ac.uk)

With the aid of genetic markers, researchers were able to provide conclusive evidence that the cancerous tumor cell evolved into a transmissible parasite. (wikipedia.org)
Furthermore, molecular genetic markers were used to resolve the issue of natural transmission, the breed of origin (phylogenetics), and the age of the canine tumor. (wikipedia.org)
Cancer precision medicine draws on the presence of somatically acquired changes in the tumor, which serve as predictive markers of response to drugs and other therapies. (nature.com)

Mounting evidence suggests that the genetic disorders/mutation and diseases change not only the protein expression patterns but also membranes themselves. (lu.se)

Genetic distance calibration with the fossil record estimated the pairwise sequence divergence as 0. (unboundmedicine.com)

Detection of the marker can be direct by RNA sequencing, or indirect using allozymes. (wikipedia.org)
The detection of prenatal structural anomalies should lead to further genetic evaluation so that many of these conditions can be identified before birth. (medscape.com)

Markers can exhibit two modes of inheritance, i.e. dominant/recessive or co-dominant. (wikipedia.org)
If the genetic pattern of homo-zygotes can be distinguished from that of hetero-zygotes, then a marker is said to be co-dominant. (wikipedia.org)
Generally co-dominant markers are more informative than the dominant markers. (wikipedia.org)

In this chapter we will present the usefulness of genetic DNA testing of skeletonized remains for human identification, by using automate DNA extraction from three different human bone types: tooth, femur and petrous pyramid. (intechopen.com)

Envisioning a new era: Complete genetic information from routine, telomere-to-telomere genomes. (amedeo.com)

Limitations to the quantitative application of this method can be addressed by adopting a multi-locus approach that integrates information from multiple markers. (biomedcentral.com)

Many genetic disorders can be detected early in pregnancy using various noninvasive and invasive techniques. (medscape.com)

Anatomy27

Organisms20

Diseases10

Chemicals and Drugs37

Analytical, Diagnostic and Therapeutic Techniques and Equipment56

Psychiatry and Psychology2

Phenomena and Processes109

Disciplines and Occupations13

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture4

Humanities1

Information Science11

Named Groups4

Health Care22

Geographicals5

Microsatellite23

Populations15

Variants15

Genomic6

Variation6

Genes6

Polymorphism6

Diversity9

Ancestry informative4

Loci6

Gene12

Abstract1

Highly informative1

Alleles3

Genome11

Recombination2

SNPs2

RFLP1

Variability3

Restriction1

Characterization2

Susceptibility2

Chromosomal2

Genetics3

Species6

Mitochondrial1

Differentiation1

Linkage map2

Sequences2

Chromosome2

Genealogy2

Detect1

Analyzer1

Accessions1

Sequence data1

Biomarkers1

Autosomal1

High density1

Livestock1

PKD12

Tumor3

Protein1

Divergence1

Detection2

Dominant3

Identification1

Genomes1

Multiple markers1

Invasive1