• Pentacel, DTaP/ IPV/ Hib (diphtheria & tetanus toxoids/ acellular pertussis vaccine/poliovirus vaccine inactivated/haemophilus influenzae type b vaccine) dosing, indications, interactions, adverse effects, and more. (medscape.com)
  • Hib vaccine can prevent Haemophilus influenzae type b (Hib) disease . (healthychildren.org)
  • Hib vaccine may be given as a stand-alone vaccine, or as part of a combination vaccine (a type of vaccine that combines more than one vaccine together into one shot). (healthychildren.org)
  • The National Immunisation Program provides free combined Hib and meningococcal C vaccine for protection against Haemophilus influenzae type b (Hib) and meningococcal group C disease to children at 12 months of age. (vic.gov.au)
  • A hypothesis testing case-control study evaluated automated medical records in the Vaccine Safety Datalink (VSD) for organic Hg exposure from Thimerosal in Haemophilus influenzae type b (Hib)-containing vaccines administered at specific times within the first 15 months of life among subjects diagnosed with pervasive developmental disorder (PDD) ( n = 534) in comparison to controls. (springer.com)
  • Forty-three renal transplant recipients with well-functioning allografts were immunized with H. influenzae type b vaccine in order to investigate the immune response. (scienceopen.com)
  • After obtaining basal serum samples, the patients and the control subjects were immunized with H. influenzae type b conjugate vaccine. (scienceopen.com)
  • Efficacy of Haemophilus influenzae type b conjugate vaccine PRP-T. (scienceopen.com)
  • Efficacy of the Haemophilus influenzae type b (Hib) conjugate vaccine PRP-T (Pasteur-Merieux) was evaluated in a controlled community intervention study in the Oxford region, UK. (scienceopen.com)
  • For more information, see the Centers for Disease Control and Prevention's (CDC) Haemophilus Influenzae type b (Hib) vaccine information statement . (msdmanuals.com)
  • The recommended form of prevention of the type b form of H. influenzae is a series of the Hib vaccine and boosters, which are most often given under the age of 5, and sometimes in conjunction with other vaccines in the form of the DTaP-IPV/Hib vaccine. (wikipedia.org)
  • Participants were enrolled between September 6, 2011, and October 9, 2011 (year 1), and from October 9, 2012, through October 21, 2012 (year 2), and were randomly assigned in a 1:1 allocation to receive 1 of the 2 vaccine types. (medscape.com)
  • The rapid and unequivocal capsular typing method that is described will be particularly important for typing invasive H. influenzae strains isolated from recipients of H. influenzae type b vaccine. (ox.ac.uk)
  • Haemophilus influenzae type b (Hib) vaccine, click here . (wikidoc.org)
  • How should Haemophilus Influenzae type B (HiB) Vaccine be used? (cgh.com.sg)
  • This virus was named Influenza B and the inactivated influenza vaccine had to be bivalent to provide protection against both types of influenza viruses (Figure 1). (medscape.com)
  • Key words: vaccines - immunization - combination vaccines - DTP/Hib vaccine The combined diphtheria-tetanus-pertussis- Haemo- philus influenzae type b (DTP/Hib) vaccine allows for a reduction in the number of required injections, thus im- proving compliance to the vaccination schedule and high- er vaccination coverage. (vdocuments.mx)
  • Persistence of immunity following a booster dose of Haemophilus influenzae type B-Meningococcal serogroup C glycoconjugate vaccine: follow-up of a randomized controlled trial. (ox.ac.uk)
  • A new combination haemophilus influenzae type B and Neisseria meningitidis serogroup C-tetanus toxoid conjugate vaccine for primary immunization of infants. (ox.ac.uk)
  • We conducted a phase 3 randomized controlled trial looking at the immunogenicity and safety of a novel combined Haemophilus influenzae type b and Neisseria meningitidis serogroup C tetanus toxoid conjugate vaccine, Hib-MenC-TT in a 2-, 3-, and 4-month primary infant immunization schedule. (ox.ac.uk)
  • Your child should not receive this vaccine if he or she has had an allergic reaction to Haemophilus b conjugate vaccine, hepatitis B vaccine, or yeast. (stlukes-stl.com)
  • Haemophilus influenzae type b can cause many different kinds of infections. (healthychildren.org)
  • Haemophilus influenzae Infections Haemophilus influenzae are gram-negative bacteria that can cause infection in the respiratory tract, which can spread to other organs. (msdmanuals.com)
  • H. influenzae is responsible for a wide range of localized and invasive infections, typically in infants and children, including pneumonia, meningitis, or bloodstream infections. (wikipedia.org)
  • Haemophilus influenzae type b ( Hib ) is a leading cause of childhood bacterial meningitis , pneumonia , and other serious infections . (bvsalud.org)
  • H.influenzae is a gram-negative , cocco-bacillary , facultatively anaerobic pathogenic bacterium that can cause infections in people of all ages ranging from mild, such as an ear infection, to severe, such as a bloodstream infection. (wikidoc.org)
  • Haemophilus influenza infections are caused by the bacterium Haemophilus influenza . (wikidoc.org)
  • H. influenzae , including Hib, can cause many different kinds of infections . (wikidoc.org)
  • All children with infections due to H influenzae type b had excellent responses to moxalactam therapy. (houstonmethodist.org)
  • Moxalactam administered parenterally, at a dose of 113 to 150 mg/kg/d in three or four divided doses is effective therapy for serious infections in children due to H influenzae type b and selected other organisms. (houstonmethodist.org)
  • Prevents infections caused by hepatitis B virus and Haemophilus influenzae type b virus. (stlukes-stl.com)
  • Haemophilus influenzae may make any one of six chemically distinct capsular polysaccharides, but only strains of capsular serotype b commonly cause systemic infection (e.g., meningitis) in humans. (jci.org)
  • The probe hybridized to an identical sized (4.4 kb) fragment of EcoRI-digested chromosomal DNA from eight independently isolated type b strains. (jci.org)
  • In 1930, two major categories of H. influenzae were defined: the unencapsulated strains and the encapsulated strains. (wikipedia.org)
  • The mutant strains were less tolerant of acidic pH and the wild type Rd KW20 could not tolerate low pH in the presence of fluoramide , a urease specific inhibitor , confirming that both nickel transport and urea hydrolysis are a central process in pH control. (rsc.org)
  • H. influenzae nimR and nikQ strains were deficient in urease activity , but this could be specifically restored by the addition of excess Ni 2+ . (rsc.org)
  • Some H influenzae strains have no capsule and are termed nonencapsulated H influenzae or nontypeable H influenzae (NTHi). (medscape.com)
  • H. influenzae colonizes the nasopharynx of up to 75% of the population, from where the Hib strains in particular can invade the bloodstream and subsequently pass to the central nervous system. (biomedcentral.com)
  • A total of 172 H. influenzae strains of known capsular type (determined genetically) comprising all capsular types and noncapsulate strains were tested by PCR capsular typing. (ox.ac.uk)
  • When used in conjunction with PCR primers derived from the capsular gene bexA, capsulate, noncapsulate, and capsule-deficient type b mutant strains could be differentiated. (ox.ac.uk)
  • PCR capsular typing overcomes the problems of cross-reaction and autoagglutination associated with the serotyping of H. influenzae strains. (ox.ac.uk)
  • Haemophilus influenzae type b (seven ampicillin-resistant strains) was the etiologic agent for 32 children. (houstonmethodist.org)
  • The reactivity and specificity of the LAMP assays were confirmed using six serotypes and non-typeable H. influenzae strains, plus eight strains of other Haemophilus species and non-Haemophilus genera. (figshare.com)
  • H. influenza type b is the most common type among capsular H.influeza. (wikidoc.org)
  • Haemophilus influenzae type b (Hib) is bacteria that commonly causes bacterial meningitis and pneumonia and is the leading cause of other invasive diseases, such as septic arthritis (joint infection), epiglottitis (infection and swelling of the epiglottis) and cellulites (rapidly progressing skin infection which usually involves the face, head, or neck). (who.int)
  • Using a well-characterized rat model of H. influenzae systemic infection, we showed that type b transformants elicited by the cloned DNA were pathogenic, causing bacteremia and meningitis, whereas the untransformed capsule-deficient H. influenzae organisms were not. (jci.org)
  • Polysaccharide of the causative agent was detected in the CSF of 14 out of 15 patients with Haemophilus influenzae type b meningitis, in 18 out of 23 patients with group A, and in two out of four patients with group C meningococcal meningitis. (bmj.com)
  • However, Haemophilus influenzae type b strain Eagan (Hib), a causative agent of bacterial sepsis and meningitis in young children, disrupted in its hktE gene is not attenuated in virulence, and retains the ability to rapidly scavenge H 2 O 2 . (biomedcentral.com)
  • Haemophilus influenzae infection is a mild and self-limited disease in the healthy population. (scienceopen.com)
  • Haemophilus influenzae type b (Hib) is one of the leading causes of invasive bacterial infection in young children worldwide. (ox.ac.uk)
  • Tell your doctor if your child has any type of illness or infection (such as a cold or the flu), especially if your child has a fever. (stlukes-stl.com)
  • Haemophilus influenzae can be encapsulated (serotypes a-f) or unencapsulated, nontypeable (NTHi) ( 1 ). (cdc.gov)
  • Nontypeable Haemophilus influenzae (NTHi) commonly infects patients with cystic fibrosis (CF), especially early in childhood. (nih.gov)
  • Haemophilus influenzae (Lehmann and Neumann) Winslow et al. (atcc.org)
  • A 4.4-kb EcoRI fragment, common to both DNA clones, was used to characterize clinical isolates representing all six encapsulated serotypes as well as several capsule-deficient H. influenzae by Southern hybridization analysis. (jci.org)
  • To address this issue, we developed a rapid, simple, and cost-effective method for detecting serotypes of H. influenzae. (figshare.com)
  • Some types of H. influenzae contain a polysaccharide capsule around the outer membrane to aid in protection and colonization. (wikipedia.org)
  • A virulent H. influenzae type b strain was used to construct a lambda library of chromosomal DNA in Charon 4. (jci.org)
  • The most virulent strain is H influenzae type b (Hib). (medscape.com)
  • Haemophilus influenzae is a common pathogen among children and immuno-comprised adults with clinical manifestations that are largely type specific. (biomedcentral.com)
  • PCR primers were designed from capsule type-specific DNA sequences cloned from the capsular gene cluster of each of the six capsular types. (ox.ac.uk)
  • We designed LAMP primer sets based on published sequences for H. influenzae capsular types a, c, d, e, and f. (figshare.com)
  • Haemophilus influenzae (formerly called Pfeiffer's bacillus or Bacillus influenzae) is a Gram-negative, non-motile, coccobacillary, facultatively anaerobic, capnophilic pathogenic bacterium of the family Pasteurellaceae. (wikipedia.org)
  • H. Influenzae is a small Gram-negative bacterium, approximately 0.3 micrometer to 1 micrometer. (wikipedia.org)
  • The cell wall of H. influenzae bacterium contains various proteins, referred to as autotransporters, for adherence and colony formation. (wikipedia.org)
  • Haemophilus influenzae tipo b: situação epidemiológica no Estado de Minas Gerais, Brasil, 1993 a 1997 Haemophilus influenzae type b: epidemiological situation in the State of Minas Gerais, Brazil, 1993-1997 by: Sybelle de Souza Castro Miranzi, et al. (uitm.edu.my)
  • Types of pneumonia and their radiologic characteristics are summarized in the table below. (medscape.com)
  • Haemophilus influenzae is a small (1 µm × 0.3 µm), pleomorphic, gram-negative coccobacillus. (medscape.com)
  • A minority of non-typeable, or unencapsulated, H. influenzae employ a variety of attachment techniques, such as pili, adhesins, or Hia and Hap proteins. (wikipedia.org)
  • Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates. (bvsalud.org)
  • The data presented here have implications both for understanding early CF lung disease pathogenesis and for the treatment of early, asymptomatic colonization of patients with CF with H. influenzae. (nih.gov)
  • The incubation period (time between exposure and first symptoms) of H. influenzae disease is not certain but could be as short as 7 days. (wikidoc.org)
  • Its use for studying the expression of type b capsule and virulence. (jci.org)
  • Molecular cloning of DNA was used to investigate the expression of type b capsule and its association with H. influenzae virulence. (jci.org)
  • These studies provide a basis for pursuing the molecular analysis of the epidemiology and virulence of pathogenic H. influenzae. (jci.org)
  • After 6 and 12 weeks, serum samples obtained again to determine H. influenzae type b antibody titers. (scienceopen.com)
  • A(H1N1) and Middle East respiratory syndrome corona- virus and for herpes simplex virus types 1 and 2. (cdc.gov)
  • The crystal structure of the prephenate dehydrogenase component (HinfPDH) of the TyrA protein from H. influenzae Rd KW20 in complex with the inhibitor tyrosine and cofactor NAD(+) has been determined to 2.0 Å resolution. (rcsb.org)
  • Growth rates of the H. influenzae nimR and nikQ mutants were reduced in chemically defined media compared to the wild type and the mutants were unable to grow in the presence of EDTA . (rsc.org)
  • Hydroperoxidase-deficient hktE - pgdx - H. influenzae Rd showed a slightly affected aerobic growth phenotype in rich broth, while, in chemically defined medium, growth was completely inhibited by aerobic conditions, unless the medium contained an amino acid/vitamin supplement. (biomedcentral.com)
  • H. Influenzae type b, also known as Hib, is the most common form, recognizable by its polyribosyl ribitol phosphate (PRP) capsule, and found mostly in children. (wikipedia.org)
  • H. influenzae prefers to bind to mucus linings or non-ciliated epithelial cells, which is facilitated by Hap𝘴 autotransporters in the cell wall binding with unknown receptors within the epithelium. (wikipedia.org)
  • Growth experiments with hydroperoxidase-deficient hktE - pgdx - H. influenzae Rd suggest that the cytotoxicity inflicted by the continuous accumulation of H 2 O 2 during aerobic growth brings about bacteriostasis rather than bacterial killing. (biomedcentral.com)
  • Treatment consists of antibiotics, however H. influenzae is often resistant to the penicillin family but amoxicillin/clavulanic acid can be used in mild cases. (wikipedia.org)
  • Two independently isolated recombinant phage were isolated from the library and were found to possess DNA necessary for expression of type b capsule. (jci.org)