Influenza focus. Medical search. Frequent questions

Although CEIRR is primarily focused on influenza, the network also will study SARS-CoV-2, the virus that causes COVID-19, and other emerging viruses of pandemic potential. (nih.gov)

On 11 June 2009, a new strain of H1N1 influenza was declared to be a pandemic (Stage 6) by the WHO after evidence of spreading in the southern hemisphere. (wikipedia.org)
The 13 November 2009 worldwide update by the WHO stated that "[a]s of 8 November 2009, worldwide more than 206 countries and overseas territories or communities have reported [503,536] laboratory confirmed cases of pandemic influenza H1N1 2009, including over 6,250 deaths. (wikipedia.org)
Although the last influenza H1N1 pandemic in 2009 was mild, fear prevails that the next one might not be (1,2). (who.int)
Effective risk communication is an essential element the avian influenza H5N1 and the pandemic influenza for outbreak management and health emergency A/H1N1 outbreaks in 2005 and 2009, respectively. (who.int)
15.6% for the A/H1N1 strain) during the 2005/2006 influenza season. (pharmacytimes.com)
Many national and international health agencies recommended the use of face masks during the 2009 influenza A (H1N1) pandemic. (cambridge.org)
Pandemic influenza A (H1N1) virus emerged in Mexico in early 2009 and rapidly spread worldwide. (cambridge.org)
The two influenza A virus subtypes have cocirculated in human populations since 1977: influenza A (H1N1) and A (H3N2). (cdc.gov)
Reassortment between influenza A (H1N1) and A (H3N2) viruses resulted in the circulation of A (H1N2) virus during the 2001-02 and 2002-03 influenza seasons. (cdc.gov)
In April 2009, a novel influenza A (H1N1) virus, influenza A(H1N1)pdm09-which was different from currently circulating influenza A (H1N1) viruses-emerged and its subsequent spread resulted in the first pandemic of the 21st century. (cdc.gov)
Three is for trivalent, which have H1N1, H3N2, and 1 influenza B virus from 1 B virus lineage. (cdc.gov)
Influenza A(H1N1)pdm09 occurred actively 3 weeks thereafter, and then co-circulated highly with influenza B through the end of March 2020. (health.mil)
Starting at surveillance week 45 (3-9 Nov. 2019), influenza B was the predominant influenza type, followed by high activity of influenza A(H1N1)pdm09 three weeks thereafter. (health.mil)
Both influenza B and influenza A(H1N1)pdm09 were then highly co-circulated through surveillance week 13 (22-28 March 2020). (health.mil)
The epidemiological mechanisms behind the W-shaped age-specific influenza mortality during the Spanish influenza (H1N1) pandemic 1918-19 have yet to be fully clarified. (hindawi.com)
There have been three influenza pandemics in the 20th century, initially observed in 1918, 1957, and 1968, respectively, referred to as the Spanish (H1N1), Asian (H2N2), and Hong Kong (H3N2) influenza [ 1 ]. (hindawi.com)
i) The influenza (H1N1) virus responsible for the 1918-19 pandemic was closely related to foregoing H1N1 virus(es) that might have widely circulated earlier than 1918. (hindawi.com)
We used high-throughput B cell receptor sequencing of plasma cells produced following AS03-adjuvanted and non-adjuvanted 2009 pandemic H1N1 vaccination, as well as pre-pandemic seasonal influenza vaccination to elucidate the effect of the adjuvant on the humoral immune response. (nature.com)
The latest influenza pandemic arose in 2009, and was caused by a swine-origin H1N1 virus (pH1N1), and resulted in an estimated 300,000 deaths within the first 12 months 3 . (nature.com)
While at the moment attention is focused on the recent emergence of a new influenza A(H1N1) virus, other influenza viruses, including the avian influenza A(H5N1) strains, are still a cause for concern. (thepoultrysite.com)
Among a sample of participants of all ages, the antibody testing of stored sera specimens from NHANES 2007-2008 was conducted to determine population levels of pre-pandemic cross reactive antibody to the 2009 pandemic influenza A/H1N1 virus and related influenza A/H1N1 viruses prior to the spread of the novel 2009 H1N1 virus. (cdc.gov)
This data release contains the hemagglutination inhibition assay titers to 2009 H1N1 and two past H1N1 influenza viruses. (cdc.gov)
Antibody titers against 2009 H1N1 and two past H1N1 influenza viruses were measured with the hemagglutination inhibition (HI) assay following standard procedures by Focus Diagnositcs, Inc., Cypress, CA. (cdc.gov)
H1GMT2009 : Geometric mean hemagglutination inhibition (HI) titer against the influenza A/H1N1 virus A/California/7/2009. (cdc.gov)
H1GMT2007 : Geometric mean hemagglutination inhibition (HI) titer against the influenza A/H1N1 virus A/Brisbane/59/2007. (cdc.gov)
H1GMT1976 : Geometric mean hemagglutination inhibition (HI) titer against the influenza A/H1N1 virus A/New Jersey/8/1976. (cdc.gov)
To create the vaccine candidate, researchers used the stem of an H1N1 influenza virus. (medscape.com)
The fact that the H1N1 candidate vaccine was effective against H5N1 infection - a different influenza subtype - suggests the antibodies the vaccine induces can be protective against other "group 1" influenza subtypes, including H1 and H5. (medscape.com)
Diagnostic influenza tests aid with identification of influenza types A and B and influenza A subtypes 2009 H1N1, H1, H3, H5, N1, and N2. (medscape.com)

24 Between 1970 and 2000, the trivalent influenza vaccine containing two strains of type A influenza and one strain of type B influenza was primarily recommended for the elderly. (nvic.org)
These novel strains are unaffected by any immunity people may have to older strains of human influenza and can therefore spread extremely rapidly and infect very large numbers of people. (wikipedia.org)
Most influenza strains can be inactivated easily by disinfectants and detergents. (wikipedia.org)
Avian influenza is an infectious disease of birds caused by type A strains of influenza virus. (gov.hk)
NIAID is pursuing a universal influenza vaccine to provide durable protection against multiple influenza virus strains. (nih.gov)
Influenza can also undergo a more significant and abrupt genomic change called antigenic shift, in part due to the mixing of strains in animals like birds or pigs. (sabin.org)
While monitoring influenza virus resistance as it develops, researchers are prioritizing further investigations to decrease the risk of resistant strains. (pharmacytimes.com)
Although currently available antiviral drugs can reduce the symptoms of influenza and limit virus transmission, the possibility of selecting resistant strains still exists, meaning influenza treatment continues to be a challenge. (pharmacytimes.com)
As a result of these antigenic changes, antibodies produced to influenza viruses as a result of infection or vaccination with earlier strains may not be protective against viruses circulating in later years. (cdc.gov)
Avian influenza is a viral disease caused by various strains of avian influenza viruses that can be classified as low pathogenic avian influenza (LPAI) or highly pathogenic avian influenza (HPAI). (usgs.gov)
Most AI strains are classified as low pathogenic avian influenza (LPAI) and cause few clinical signs in infected birds. (usgs.gov)
On the other hand, highly pathogenic avian influenza (HPAI) strains frequently fatal to birds and easily transmissible between susceptible species. (usgs.gov)
It has been thought that Eurasian strains of avian influenza viruses enter the United States through the Pacific Flyway (Alaska to Baja California) and that this route is the most likely avenue for emerging Eurasian AIV strains to enter North America. (usgs.gov)
St. Jude researchers and physicians study how new influenza strains emerge in humans and cause disease. (stjude.org)
To improve vaccine effectiveness (VE) against influenza viruses, the strains used in the influenza vaccine need to be updated regularly based on the surveillance findings. (health.mil)
Next-generation vaccines that utilize T cells could potentially overcome the limitations of current influenza vaccines that rely on antibodies to provide narrow subtype-specific protection and are prone to antigenic mismatch with circulating strains. (mdpi.com)
This has provided hope for the design of a universal vaccine able to prime against diverse influenza virus strains and subtypes. (mdpi.com)
The culprit behind the flu in babies and toddlers is the influenza virus, of which there are multiple strains that circulate around the world every year. (whattoexpect.com)
the partners plan to exchange scientific information on avian influenza, share viral isolates, and may eventually manufacture human vaccines against avian viral strains. (nationalacademies.org)
On-going research is focused on the development of appropriate vaccines against A(H5N1) circulating strains for use in humans. (thepoultrysite.com)
The NIH's National Institute of Allergy and Infectious Diseases (NIAID) hopes to develop a vaccine that will overcome the challenges associated with seasonal changes among influenza strains. (medscape.com)

The CEIRR sites will conduct studies in the United States and internationally that follow cohorts of people to evaluate influenza-related research areas, such as understanding immune responses to vaccination and infection and identifying which immunological factors can determine influenza disease severity. (nih.gov)
Thorough cooking of poultry meat and eggs, with centre temperature reaching at least 70°C, can prevent avian influenza infection as it inactivates the virus. (gov.hk)
however, M2Is could not be used to treat influenza B infection (IBI) due to the lack of M2 protein on its surface. (pharmacytimes.com)
We conducted a systematic review [ Reference Moher 6 ] to investigate the evidence supporting the effectiveness of face masks in reducing influenza virus infection under controlled and natural conditions. (cambridge.org)
Influenza is an acute respiratory disease caused by infection with influenza viruses. (cdc.gov)
Complications of influenza infection include secondary bacterial pneumonia and exacerbation of underlying chronic health conditions. (cdc.gov)
[1-5] Aspirin and other salicylate-containing medications are contraindicated for children and adolescents with influenza-like illness, as their use during influenza infection has been associated with the development of Reye syndrome. (cdc.gov)
Vaccination is the primary intervention used to curb influenza virus infection, and the WHO recommends immunization for at-risk individuals to mitigate disease. (mdpi.com)
We discuss the different vectored vaccines that have been or are currently in clinical trials, with a forward-looking focus on immunogens that may be protective against seasonal and pandemic influenza infection, in the context of viral-vectored vaccines. (mdpi.com)
Seasonal influenza vaccination is considered the main strategy to protect against influenza viruses, combat influenza infection, and reduce disease severity. (health.mil)
Influenza vaccination is the most effective means of preventing influenza virus infection and its potentially severe complications [ 7 ], and efforts to promote immunization are mainly directed toward providing vaccinations for people at risk for influenza complications and their contacts. (biomedcentral.com)
1 - 3 Influenza infection may accelerate acute thrombotic vascular events, particularly in patients with ischemic heart disease and cerebrovascular disease. (cmaj.ca)
For pandemic influenza vaccination, this suggests that the adjuvant could improve B cell responses by either increasing activation of naïve B cells, or by increasing the activation and adaptation of pre-existing memory B cells generated through infection or immunization with seasonal influenza from earlier years to become specific towards the pandemic strain 11 . (nature.com)
Frederick noted that healthcare workers in any hospital setting are considered to be at high risk of becoming infected with influenza and passing the infection to others, a similar concern with the COVID-19 virus. (health.mil)
According to the CDC, COVID-19 and influenza are both contagious respiratory illnesses, albeit each caused by infection from a different virus. (health.mil)
Using these transcriptomic data, we have focused our analysis on the modulation of the p53 pathway in response to influenza infection. (nih.gov)
January 26 and February 6, Yueyang City Miluo City, the emergence of avian influenza H7N9 confirmed cases of human infection case. (flutrackers.com)
The article of J.P. Dudley published in the same issue of Eurosurveillance examines the age- and sex-specific rates of infection and mortality for human cases of avian influenza A(H5N1) virus in Egypt, concluding that they differ markedly from those recorded in other countries. (thepoultrysite.com)
An HI titer of ≥40 indicates prior infection with an influenza virus antigenically similar to the tested virus. (cdc.gov)

The first experimental influenza vaccines were given to soldiers in World War II. (nvic.org)
We're working to accelerate the development of next generation, broadly protective vaccines for influenza to better prepare for and prevent the next pandemic. (sabin.org)
Refer to NACI's Supplemental Statement - Mammalian Cell Culture-Based Influenza Vaccines for further details. (canada.ca)
This document, the "Advisory Committee Statement: Canadian Immunization Guide Chapter on Influenza and National Advisory Committee on Immunization (NACI) Statement on Seasonal Influenza Vaccine for 2020-2021", updates NACI's recommendations regarding the use of seasonal influenza vaccines. (canada.ca)
Outline updates on the advisory committee on immunizations practices, recommendations for 2021-2022 influenza vaccination season, discuss general influenza vaccination guidance during the COVID-19 pandemic, and describe clinical considerations and best practices for coadministration of influenza vaccines and COVID-19 vaccines. (cdc.gov)
To address this threat, there are concrete steps the United States should take to combat chronic challenges with influenza vaccines. (csis.org)
v In preparation, the CDC has purchased 9.3 million additional doses of influenza vaccines for uninsured adults as compared to last year's 500,000. (csis.org)
Influenza pandemics require rapid deployment of effective vaccines for control. (nature.com)
The capacity to rapidly develop and manufacture effective vaccines in large quantities is key in combating influenza pandemics. (nature.com)
used phage display libraries, and surface plasmon resonance to determine binding locations, and affinity of the antibodies produced in response to both adjuvanted and non-adjuvanted pandemic influenza vaccines 12 , 13 . (nature.com)
GSK today announced it started shipping its quadrivalent influenza vaccines to U.S. healthcare providers and pharmacies for the 2021-22 flu season. (drugstorenews.com)
from children to adults, including influenza vaccination during the 2020-2021 season," said Dr. Leonard Friedland, vice president, director of Scientific Affairs and Public Health, GSK Vaccines. (drugstorenews.com)
A recent claims analysis commissioned by GSK and conducted by Avalere Health showed a significant and sustained drop in immunization rates for recommended vaccines among adolescents and adults throughout the pandemic in 2020, including influenza immunization. (drugstorenews.com)

NIAID established the Centers of Excellence for Influenza Research and Response (CEIRR) to study natural history, transmission, and pathogenesis of influenza and provide an international research infrastructure to address influenza outbreaks. (nih.gov)
The sites will prepare studies that could be rapidly launched as part of emergency research responses to outbreaks of influenza and other emerging viral pathogens. (nih.gov)
Objective To review the effects of school closures on pandemic and seasonal influenza outbreaks. (bmj.com)
This systematic review assesses the effects of school closures on the transmission of influenza, including data from the recent 2009 pandemic as well as from previous pandemics and seasonal outbreaks. (bmj.com)
The available data suggest that school closure can be a useful intervention during influenza outbreaks, with the greatest benefits occurring among school-aged children. (bmj.com)
Influenza A viruses can occasionally be transmitted from wild birds to other species, causing outbreaks in domestic poultry, and may give rise to human influenza pandemics. (wikipedia.org)
In order to understand the preparedness and response to influenza outbreaks and pandemics in the WHO EMR, with particular reference to challenges and constraints specific to the Region, we reviewed peer-reviewed scientific literature, non-peer-reviewed literature, and international and national plans. (who.int)
3 Based on previous experience in H7N9 is a strain of influenza that causes mild disease in handling disease outbreaks with pandemic potential, poultry but can be severe in humans. (who.int)
Highly pathogenic avian influenza outbreaks in domestic poultry cause large economic losses to the U.S. economy. (usgs.gov)
Our research has provided important breakthroughs in several major influenza outbreaks over the years, leading to our designation as a World Health Organization Collaborating Center for Influenza and an NIH Center of Excellence for Influenza Research and Surveillance. (stjude.org)
Seasonal influenza is defined as predictable outbreaks of respiratory disease caused by various influenza viruses that spread from person to person. (csis.org)
Influenza virus causes seasonal outbreaks of clinical influenza, and has been responsible for four pandemics over the last 100 years 1 . (nature.com)
Clade 2.2 A(H5N1) influenza viruses that have been associated with human infections in Egypt since September 2008 are the ones with the most geographically disperse distribution and have caused outbreaks in poultry in over 60 countries in Asia, Africa and Europe. (thepoultrysite.com)

One strain of virus that may produce a pandemic in the future is a highly pathogenic variation of the H5N1 subtype of influenza A virus. (wikipedia.org)
In light of the recent outbreak of avian influenza (H5N1) among ducklings in Guangdong province, there are again concerns over the risk of transmission of avian influenza from poultry and their products to humans. (gov.hk)
Following the emergence of avian influenza H5N1 and the fear of its pandemic potential, having an adequate preparedness plan became a priority as the World Health Organization (WHO) urged every country to develop and maintain an up-to-date national influenza preparedness plan, and provided guidance on plan content (5). (who.int)
GLOBAL - A. Melidou of the Aristotle University of Thessaloniki in Greece has summarised the latest situation on H5N1 highly pathogenic avian influenza (HPAI) worldwide. (thepoultrysite.com)
In an article in Eurosurveillance , A. Melidou writes that the A(H5N1) influenza virus has re-emerged in 2003 in Asia, Africa, the Pacific Region as well as Europe and since then has become endemic in some countries. (thepoultrysite.com)
Avian influenza A(H5N1) - current situation. (thepoultrysite.com)

Getting us to a universal influenza vaccine requires collaboration and new thinking. (sabin.org)
The world needs a universal influenza vaccine (UIV) - one that is long lasting with the ability to protect against a broad spectrum of mutations. (sabin.org)
The United States should strongly support universal influenza vaccine (UIV) development. (csis.org)
Researchers are conducting the first-in-human trial of a universal influenza vaccine candidate, the National Institutes of Health (NIH) announced April 3. (medscape.com)
This phase 1 clinical trial is a step forward in our efforts to develop a durable and broadly protective universal influenza vaccine. (medscape.com)
A team of VRC scientists developed the universal influenza vaccine prototype. (medscape.com)

Influenza viruses also can cause pandemics, during which rates of illness and death from influenza-related complications can increase worldwide. (cdc.gov)
It wasn't until the 1957-58 and 1968-69 influenza pandemics that the vaccine was marketed to civilians. (nvic.org)
Influenza pandemics occur when a new strain of the influenza virus is transmitted to humans from another animal species. (wikipedia.org)
Three influenza pandemics occurred during the 20th century and killed tens of millions of people, with each of these pandemics being caused by the appearance of a new strain of the virus in humans. (wikipedia.org)
Preparedness is key to controlling influenza pandemics and epidemics. (who.int)
A comprehensive literature review was conducted to analyse the response and preparedness to influenza pandemics in the World Health Organization Eastern Mediterranean Region (WHO/EMR). (who.int)
Influenza viruses can be divided into 4 types: A, B, C, and D. Influenza type C viruses are not associated with severe disease, epidemics, or pandemics, and influenza D viruses primarily affect cattle and are not known to infect or cause illness in people, so neither will be discussed further here. (cdc.gov)
Yet, history has proven the reality of this threat with influenza pandemics in 1918, 1957-58, 1968, and 2009. (csis.org)
Such risk factors did not significantly influence the age-specific death patterns during other pandemics and inter-pandemic influenza epidemics. (hindawi.com)

They also will undertake projects on influenza surveillance, including transmission of influenza viruses from animals to humans (zoonotic transmission) to better understand how influenza viruses evolve, adapt, and transmit. (nih.gov)
citation needed] The World Health Organization (WHO) has produced a six-stage classification that describes the process by which a novel influenza virus moves from the first few infections in humans through to a pandemic. (wikipedia.org)
To identify the general public's perceptions of the overall risk communication strategy carried out by Chinese public health agencies during the first wave of avian influenza A(H7N9) outbreak in humans in 2013. (who.int)
Antigenic shift results in a completely new strain against which humans have little or no immunity-potentially causing an influenza pandemic. (sabin.org)
Our center focuses exclusively on the threat to humans from influenza viruses of animals. (stjude.org)
The OIE is developing influenza surveillance guidelines that encompass birds, domestic mammals, wildlife, and humans. (nationalacademies.org)
surveillance focused on the subset of avian influenza viruses that pose significant risk of infecting humans, including certain viruses of low pathogenicity in poultry. (nationalacademies.org)

The USGS National Wildlife Health Center (NWHC) in collaboration with multiple partners conducts research into the ecology of avian influenza virus and surveillance for highly pathogenic avian influenza (HPAI) viruses leading to several significant findings towards early detection and response to HPAI. (usgs.gov)
AV5124 is also a potent inhibitor of highly pathogenic avian influenza viruses circulating in nature, indicating the potential for seasonal or pandemic influenza treatment, and for pandemic preparedness. (fox40.com)

Epidemics of influenza typically occur during the winter months in temperate regions and have been responsible for an average of approximately 36,000 deaths/year in the United States during 1990--1999 ( 1 ). (cdc.gov)
The sharp rise in influenza-associated acute respiratory illnesses that occurs during annual seasonal epidemics results in increased numbers of visits to physicians' offices, walk-in clinics, and emergency departments. (cdc.gov)

Of more immediate concern, experts warn that if Americans do not practice appropriate prevention measures such as seeking influenza vaccination, washing their hands, social distancing, and wearing a mask, circulating seasonal influenza and Covid-19 will exacerbate one another, adding further strain to an already overburdened health system. (csis.org)

Study selection Studies were included if they reported on a seasonal or pandemic influenza outbreak coinciding with a planned or unplanned school closure. (bmj.com)
Three pieces of epidemiological information were assessed: (i) the epidemic records containing the age-specific numbers of cases and deaths of influenza from 1918-19, (ii) an outbreak record of influenza in a Swiss TB sanatorium during the pandemic, and (iii) the age-dependent TB mortality over time in the early 20th century. (hindawi.com)
The ongoing pandemic outbreak has overlapped with the annual Northern Hemisphere influenza season. (health.mil)
The chapter concludes with an example of a low-pathogen avian influenza outbreak in a group of commercial poultry farms and the steps the industry took to contain further spread of the virus, minimize the risk of exposure, and monitor and prevent further infections. (nationalacademies.org)
This guide is intended for use by local health departments as part of a multi-sector effort to coordinate planning and response to a pandemic influenza outbreak. (domesticpreparedness.com)

This report updates the 2004 recommendations by the Advisory Committee on Immunization Practices (ACIP) regarding the use of influenza vaccine and antiviral agents (CDC. (cdc.gov)
Immunization coverage was greater among the pediatric population, however, as nearly 60% of children aged 6 months to 17 years were vaccinated against influenza last year, compared with 42% of adults, the report found. (pharmacytimes.com)
To help expand influenza vaccination coverage, retail pharmacies across the United States are increasingly providing immunization services to patients. (pharmacytimes.com)
Captain Grohskopf is the CDC lead for the influenza work group of the advisory group on immunization practices. (cdc.gov)
The authors of a review on antibody declines among the elderly after vaccination reported, "In conclusion, we found no compelling evidence for more rapid decline of the influenza vaccine-induced antibody response in the elderly, compared with young adults, or evidence that seroprotection is lost at 4 months if it has been initially achieved after immunization. (buildyourcnc.com)
The United States Advisory Committee on Immunization Practices (ACIP) and health authorities throughout the world recommend annual influenza vaccinations for healthcare workers (HCWs) in order to reduce the morbidity associated with influenza in healthcare settings [ 7 - 10 ]. (biomedcentral.com)

Since 1988, the HA- and NA-producing genes of avian influenza subtype H7N9 have been deposited in GenBank 12 times, mainly representing isolates collected from wild bird hosts. (cdc.gov)

Focused antibody response to influenza linked to antigenic drift. (ox.ac.uk)

We have reviewed an extensive body of the literature on the effects of school closure on the incidence and transmission of influenza. (bmj.com)

Vaccination is associated with reductions in influenza-related respiratory illness and physician visits among all age groups, hospitalization and death among persons at high risk, otitis media among children, and work absenteeism among adults ( 8--18 ). (cdc.gov)
That is because what CDC employees did to come up with their influenza hospitalization 'estimate' was to count a lot of people hospitalized between 1979 and 2001 - not just with influenza but also with pneumonia, respiratory and circulatory illnesses - which they counted as probably associated with influenza. (nvic.org)
Again, they counted not just influenza death cases but also threw in other respiratory, circulatory, cardiac and pulmonary deaths they thought might have been associated with influenza. (nvic.org)
Typical features of influenza include abrupt onset of fever and respiratory symptoms such as cough (usually nonproductive), sore throat, and coryza, as well as systemic symptoms such as headache, muscle aches, and fatigue. (cdc.gov)
Laboratory-based influenza surveillance was conducted in the 2019-2020 influenza season among Department of Defense (DOD) beneficiaries through the DOD Global Respiratory Pathogen Surveillance Program (DODGRS). (health.mil)
Every year, the Department of Defense (DOD) Global Respiratory Pathogen Surveillance Program (DODGRS) performs routine respiratory pathogen surveillance among DOD service members and their beneficiaries, and evaluates influenza VE. (health.mil)
We sought to examine the effectiveness of influenza vaccination against admission to hospital for acute cardiovascular and respiratory conditions and all-cause death in people with type 2 diabetes. (cmaj.ca)
The focus of this research project is respiratory protection. (cdc.gov)
The company focuses on blood-borne and respiratory viral diseases, and cancers for which effective therapies are not available. (fox40.com)

DelveInsight's," Influenza A Infections-Pipeline Insights, 2014", report provides comprehensive insights about pipeline drugs across this indication. (prnewswire.com)
A key objective of the report is to establish the understanding for all the pipeline drugs that fall under Influenza A Infections. (prnewswire.com)
This report provides information on the therapeutic development based on the Influenza A Infections dealing with all the pipeline drugs, comparative analysis at various stages covering Filed, Phase III, Phase II, Phase I, IND filed, Preclinical, Discovery and unknown stages, therapeutics assessment by monotherapy and combination products and molecule type drug information. (prnewswire.com)
Further studies in controlled settings and studies of natural infections in healthcare and community settings are required to better define the effectiveness of face masks and respirators in preventing influenza virus transmission. (cambridge.org)
Influenza Tests are laboratory based tests used to identify active or suspected influenza infections, using a combination of molecular diagnostics and immunoassay. (medicaldevice-network.com)
Evidence from animal models shows that T cells can provide heterosubtypic protection and are crucial for immune control of influenza virus infections. (mdpi.com)
His clinical focus is on infections in patients with hematologic malignancies and infections in patients with critical illnesses. (mayo.edu)

The existing evidence on HCW influenza vaccination and the reduction of morbidity associated with influenza in patients being cared for by a HCW in health care settings was considered in the context of ethics and acceptability. (canada.ca)
Annual influenza vaccination is recommended for healthcare workers (HCWs) in order to reduce the morbidity associated with influenza in healthcare settings. (biomedcentral.com)

Vaccination with the 2009 hemagglutinin induced an antibody response tightly focused on this common surface that is capable of selecting current antigenic drift variants in H1N1pdm09 influenza viruses. (ox.ac.uk)
Antibody to seasonal inactivated influenza vaccine declines in the months following vaccination. (buildyourcnc.com)
Rapid Decline of Influenza Vaccine-Induced Antibody in the Elderly: Is it Real, or Is It Relevant? (buildyourcnc.com)
The aim of this study was to determine the Haemophilus influenza type b (Hib) antibody concentrations in beta-thalassaemia patients with or without spleens. (scialert.net)
They will not be exposed to influenza as part of the study but will periodically provide blood samples that will undergo testing to characterize and measure anti-influenza antibody levels. (medscape.com)

There was only one deadly influenza pandemic in the last 100 years that killed the young and healthy in great numbers and that was the 1918 Spanish Flu. (nvic.org)
At least 50 million people were killed by the 1918 influenza strain. (sabin.org)
Realistically, we will probably never see something like Captain Trips (although some scientists believe that the plague may have been a virus rather than the bacteria which is normally associated with bubonic plague) even the 1918, influenza pandemic didn't kill more than about five or ten percent of the world's population. (allnurses.com)
Furthermore, let's say that the general public faced a 10% chance of death (from contracting the virus) while health care workers faced a 50%+ chance of getting the disease (again more like the Plague of the Middle Ages than the 1918 influenza which usually killed young adults and adolescents). (allnurses.com)
During the influenza pandemic of 1918-19, Rupert Blue served as civilian. (enotes.com)
Over 100 years ago, the 1918 influenza pandemic killed 675,000 Americans. (csis.org)
The present study aimed to develop a formal hypothesis: tuberculosis (TB) was associated with the W-shaped influenza mortality from 1918-19. (hindawi.com)
The most devastating pandemic known in human history is the Spanish influenza 1918-19. (hindawi.com)
As an example, it has been described that those with tuberculosis (TB) in 1918 may have been more likely to die of influenza compared with those without TB [ 11 , 12 ]. (hindawi.com)

Captured in 2011, this transmission electron microscopic (TEM) image depicts some of the ultrastructural details displayed by H3N2 influenza virions, responsible for causing illness in Indiana and Pennsylvania in 2011. (health.mil)

The selling of influenza vaccine has a lot to do with selling big morbidity and mortality numbers. (nvic.org)

Neuraminidase inhibitors (NIs) were used as an antiviral agent because neuraminidase can facilitate the release of viral particles by severing the sialic acid groups hemagglutinin-a surface protein influenza uses-is bound to. (pharmacytimes.com)
Unfortunately, influenza vaccine composition needs to be updated annually due to antigenic shift and drift in the viral immunogen hemagglutinin (HA). (mdpi.com)
For these reasons, it is critical that the United States strengthens its influenza vaccine infrastructure and encourages vaccine confidence and demand immediately-even as it grapples with another viral crisis. (csis.org)
Our data reveal that influenza viruses cause an overall down-regulation of the host p53 pathway and highlight this pathway and p53 protein itself as important viral targets in the altering of apoptotic processes and in cell-cycle regulation. (nih.gov)
Sera from Individuals with Narrowly Focused Influenza Virus Antibodies Rapidly Select Viral Escape Mutations In Ovo . (bvsalud.org)

Sundaram, a doctoral student in the environmental health program, was selected because of her extensive experience as an infectious disease epidemiologist researching influenza vaccine effectiveness for organizations such as the Centers for Disease Control. (umn.edu)
End-of-season influenza vaccine effectiveness (VE) was estimated using a test-negative case-control study design. (health.mil)

2 years, and persons of any age who have medical conditions that place them at increased risk for complications from influenza ( 2,5--7 ). (cdc.gov)
Influenza vaccination is the primary method for preventing influenza and its severe complications. (cdc.gov)
Persons 65 years of age and older, young children, pregnant women, and persons of any age with certain underlying health problems are at increased risk for complications of influenza and hospitalization. (cdc.gov)
4 For decades, vaccination has been the principal strategy to control influenza and its severe complications in older adults and patients with chronic illnesses, who account for most influenza-attributable deaths. (cmaj.ca)

Influenza H7N9 subtypes have been identified among wild birds globally by isolation and by using reverse transcription PCR. (cdc.gov)
Influenza A (H7N9) virus infected animals across the provinces or outside the normal season. (who.int)

Variation exists among diagnostic methods for identification of types and subtypes of influenza (see Tables 1, 2, and 3). (medscape.com)
Subtypes of influenza A are not identified. (medscape.com)

This group should consider annual influenza vaccination as part of their responsibilities to provide the highest standard of care. (canada.ca)
And that is that annual influenza vaccination is recommended for all persons aged six months and older who did not have contraindications. (cdc.gov)
Sundaram's graduate research has a focus the potential effect of repeated annual influenza vaccination. (umn.edu)
According to the CDC, annual influenza vaccination is the best way to help protect people 6 months and older against the flu. (drugstorenews.com)

Apply through our new funding opportunity announcement (FOA) Development and Optimization of Next-Generation Immunological Assays To Support Influenza Clinical Studies and Trials (UH2/UH3, Clinical Trial Not Allowed) if you can build a well-integrated, cross-disciplinary research team with diverse expertise in assay development and optimization, clinical research, immunology, and influenza virology. (nih.gov)
As one of six U.S. research institutions selected for the CEIRR network, St. Jude serves as a hub of basic and clinical research aimed at understanding and responding to influenza. (stjude.org)
SAN DIEGO , Nov. 20, 2023 /PRNewswire/ -- Viriom Inc., dedicated to advancing a pipeline of highly effective and broadly affordable treatments targeting infectious and malignant diseases globally, announces the successful completion and positive results of Phase I clinical trial for AV5124, a novel inhibitor of influenza virus replication. (fox40.com)
Based on challenges of high clinical and societal relevance and the special competencies of its cooperation partners, HZI has established Research Foci (RF), providing a synergistic, dynamic and flexible framework for the programme. (helmholtz-hzi.de)
Within each Research Focus, HZI scientists pursue the transfer of knowledge from the lab to clinical or pharmaceutical application. (helmholtz-hzi.de)
Influenza (pentavalent) vaccine is under clinical development by Vaxess Technologies and currently in Phase I for Seasonal Influenza. (pharmaceutical-technology.com)

Conclusions School closures appear to have the potential to reduce influenza transmission, but the heterogeneity in the data available means that the optimum strategy (eg, the ideal length and timing of closure) remains unclear. (bmj.com)
vii The CDC released a report in mid-September predicting that Covid-19 interventions and influenza vaccination could reduce influenza transmission in the 2020-2021 season. (csis.org)

Influenza viruses circulate around the world every year. (cambridge.org)

So, as mentioned, I'm going to present an overview of the updates of the ACIP influenza vaccine recommendations for the upcoming 2021-2022 season. (cdc.gov)
In 2022, GlobalData's Market Model methodology determined that the leading player in the influenza tests market in the US was Abbott Laboratories followed by Quidelortho, Becton Dickinson and Co, Danaher , F. Hoffmann-La Roche , Sekisui Diagnostics, DiaSorin and Thermo Fisher Scientific. (medicaldevice-network.com)
Following the widespread disruption resulting from the COVID-19 pandemic to the broader medical devices market during 2020 and 2021, the value of the influenza tests devices market within the US was expected to be over $30m in 2022. (medicaldevice-network.com)
WASHINGTON November 21, 2022 - Given the anticipated increase in COVID-19 and influenza cases this fall and winter, America's healthcare professional organizations are coming together to remind the public of the importance of vaccinations and early treatment. (acponline.org)
GSK expects to distribute more doses than it has in any previous flu season with a record supply of more than 50 million doses of its influenza vaccine for the 2021-2022 season to the U.S. market. (drugstorenews.com)

It doesn't matter if 80 percent of all flu-like illness is really caused by other viruses and bacteria and not influenza, 21 , 22 or that flu vaccine efficacy is estimated at 60 percent to 80 percent, depending upon age and what kind of vaccine is given. (nvic.org)
The U.S. Agency for Healthcare Research and Quality reported that, in 2004, there were about 37,000 Americans hospitalized for either influenza or another illness in addition to influenza, and patients over age 85 were twice as likely to die. (nvic.org)
In addition, epidemiological factors, such as the WWI practice of packing soldiers with severe influenza illness into field hospitals while soldiers with mild illness stayed outside on the battlefield, are an important determinant of whether or not a new strain of influenza virus will spur a pandemic. (wikipedia.org)
There is some evidence to support the wearing of masks or respirators during illness to protect others, and public health emphasis on mask wearing during illness may help to reduce influenza virus transmission. (cambridge.org)
Defense Health Agency officials had indicated in early December 2020, that Influenza-Like-Illness (ILI) does tend to peak during the winter months, which has been the case in the Pacific Northwest the last few years. (health.mil)
Influenza viruses cause mild to severe illness, whereas COVID-19 has caused serious illness in many, resulting in more than 500,000 deaths in the U.S. alone. (health.mil)

Influenza vaccination coverage was very low in all specialties, varying from 17.6% in the Emergency Department to 24.3% in the Surgery Department, and knowledge of influenza epidemiology and prevention was poor. (biomedcentral.com)
One of the most pressing scientific questions of the epidemiology of Spanish influenza is the atypical W-shaped curve seen in the age-specific mortality [ 3 , 4 ]. (hindawi.com)
These strategies are presented, along with background information on the biology, ecology, and epidemiology of avian influenza, by David Swayne and David Suarez of the USDA. (nationalacademies.org)

If developed and distributed equitably before the emergence of a novel influenza strain, a UIV could save millions of lives. (sabin.org)
Seasonal influenza is a perpetual public health challenge, and we continually face the possibility of an influenza pandemic resulting from the emergence and spread of novel influenza viruses," Anthony S. Fauci, MD, director of NIAID, said in a news release. (medscape.com)

Live attenuated influenza vaccine (LAIV) has been authorized for use in Canada since 2011, and was previously considered contraindicated by NACI in individuals with HIV. (canada.ca)

Roughly 150 million doses of influenza vaccine are on track for distribution in the United States for the present flu season, up from 134.5 million doses for the 2013-2014 flu season, the CDC said. (pharmacytimes.com)

In recent weeks, the CDC has repeatedly emphasized the importance of influenza vaccination this flu season to help reduce the burden of disease and the impact of influenza on the healthcare system and other critical infrastructures during the COVID-19 pandemic. (drugstorenews.com)

In more serious cases, influenza causes pneumonia, which can be fatal, particularly in young children and the elderly. (wikipedia.org)
Outcome measures included admission to hospital for acute myocardial infarction (MI), stroke, heart failure or pneumonia/influenza, and death. (cmaj.ca)

The success of treatment with M2Is is dependent on the early administration (within 48 hours) from the onset of influenza symptoms, according to the study. (pharmacytimes.com)
If Wilson was indeed suffering from such symptoms, this complication of influenza had a profound impact on world history due to the results of the Paris treaty. (enotes.com)
These side effects are not the same as having influenza, but people confuse the symptoms. (buildyourcnc.com)
Though influenza can come with vomiting, nausea and diarrhea, there are other symptoms like body aches, fever, chills, sore throat and congestion or cough that don't accompany stomach viruses. (whattoexpect.com)

2 Center of Excellence for Influenza Viruses, Child Health department National Research Centre, Giza, Egypt. (who.int)
St. Jude is distinguished as a Center of Excellence for Influenza Research and Response (CEIRR) by the National Institutes of Allergy and Infectious Diseases. (stjude.org)

Influenza (the flu) is a serious disease that can lead to hospitalization and sometimes even death. (cdc.gov)
Now, 37,000 influenza hospitalizations is five times less than the 200,000 hospitalization figure the CDC uses. (nvic.org)
In the 2017-18 influenza season, an estimated 45 million Americans fell ill with nearly 21 million seeking care from a health provider and 810,000 requiring hospitalization. (csis.org)

iii Just because we are reeling from a coronavirus pandemic does not mean we are exempt from another influenza pandemic-now or in the future. (csis.org)
Neuraminidase, or NA, is another influenza surface protein. (medscape.com)

This chapter focuses on the global phenomenon of avian influenza, its impact on the poultry industry, and potential means to control influenza transmission among birds and mammals. (nationalacademies.org)

The vaccine candidate development is part of a larger initiative to develop a universal vaccine candidate that can provide durable protection for individuals of all ages and against multiple influenza subtypes, including those with the potential to cause a pandemic. (medscape.com)
It is useful as a vaccine platform because it forms particles that can display multiple influenza HA spikes on its surface, mimicking the natural organization of HA on the influenza virus," according to the news release. (medscape.com)

For example, only 49 percent of Americans got an influenza vaccination in 2018-2019. (csis.org)
Influenza B was the predominant influenza type starting from the beginning of Nov. 2019. (health.mil)
The estimated VE (46%) indicated that the influenza vaccine during the 2019-2020 influenza season was moderately effective against these influenza viruses. (health.mil)
Influenza surveillance conducted by DODGRS during the 2019-2020 influenza season identified circulating influenza virus (sub)types, provided timely data on the genetic characteristics of the circulating viruses, and estimated influenza VE. (health.mil)
The influenza vaccine was moderately effective against influenza viruses during the 2019-2020 influenza season. (health.mil)
The objective of this report is to describe influenza surveillance trends and the end-of season VE estimates among DOD beneficiaries during the 2019-2020 influenza season. (health.mil)
The report indicated rates were lower in 2020 than in 2019, with total influenza vaccinations dropping 14-35% in 2020 compared to 2019. (drugstorenews.com)

The Centers for Disease Control and Prevention (CDC) has designated December 10 of National Influenza Vaccination Week (NIVW) to focus on young adults ages 19-24. (cdc.gov)
Officials from the US Centers for Disease Control and Prevention are urging all Americans aged 6 months and older to receive flu shots for the impending influenza season. (pharmacytimes.com)
Officials from the US Centers for Disease Control and Prevention (CDC) are urging all Americans aged 6 months and older to receive flu shots for the impending influenza season, given that less than half of the population received such vaccinations last year. (pharmacytimes.com)
However, other experts fear that the United States will not experience the same decreases in influenza cases due to the inconsistent adoption of Covid-19 prevention measures and historically low influenza vaccine uptake. (csis.org)
Efforts should be focused on improvements in vaccine uptake in this important target group as part of comprehensive secondary prevention. (cmaj.ca)
Vaccine is under development for the prevention of seasonal influenza. (pharmaceutical-technology.com)

Due to frequent mutations and reassortment in its genome, influenza is a continuously evolving virus (3). (who.int)
[8,9] However, these viruses were shown to be incompetent for reassortment with other influenza A viruses, a hallmark of the species, indicating that they are not true influenza A viruses. (cdc.gov)
See PHIL 13469, for the diagrammatic representation of how this Swine Flu stain came to be, through the "reassortment" of two different Influenza viruses. (health.mil)

Influenza, commonly known as the flu, is an infectious disease of birds and mammals. (wikipedia.org)

CEIRR replaced the Centers of Excellence for Influenza Research and Surveillance (CEIRS) program, which was supported by contracts that concluded on March 31, 2021. (nih.gov)
The USGS National Wildlife Health Center, in collaboration with the National Institutes of Health Centers of Excellence for Influenza Research and Surveillance (CEIRS), the University of Iceland, and other partners, has explored the ecology and movement of AI viruses in the North Atlantic region since 2010. (usgs.gov)
St. Jude is one of only six Collaborating Centers operating under the WHO Global Influenza Surveillance and Response System (GISRS). (stjude.org)
Because of the changing nature of these viruses, it is crucial to conduct annual surveillance to determine the circulating viruses and to detect changes in the viruses during the influenza season. (health.mil)

Anatomy15

Organisms39

Diseases23

Chemicals and Drugs49

Analytical, Diagnostic and Therapeutic Techniques and Equipment45

Psychiatry and Psychology3

Phenomena and Processes41

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture2

Humanities2

Information Science9

Named Groups3

Health Care40

Geographicals16

Emerging viruses1

H1N129

Strains21

Infection19

Vaccines13

Outbreaks13

H5N16

Universal influenza6

Pandemics9

Humans7

Highly pathogeni2

Epidemics2

Seeking influenza vaccination1

Outbreak5

Immunization6

Subtype1

Response to influenza1

Transmission of influenza1

Respiratory9

Infections7

Morbidity associated with influenza2

Antibody5

19189

H3N21

Selling of influenza vaccine1

Viral5

Vaccine Effectiveness2

Complications4

H7N92

Subtypes of influenza2

Annual influenza vaccination4

Clinical6

Reduce influenza transmission2

Circulate around the world every1

20225

Illness6

Epidemiology3

Emergence2

LAIV1

Doses of influenza1

Impact of influenza1

Pneumonia2

Symptoms4

Center of Excellence2

Hospitalization3

Another influenza2

Control influenza1

Multiple influenza2

20197

Prevention6

Reassortment3

Infectious disease1

Surveillance4