• OBJECTIVES: To examine the role of prenatal and postnatal second-hand tobacco smoke (SHS) exposure on asthma, rhinitis, and eczema development up to 16 years of age. (lu.se)
  • During prenatal and postnatal time periods, epigenetic processes fine-tune neurodevelopment towards an end product that determines how an organism interacts with and responds to exposures and experiences throughout life. (nih.gov)
  • toxic effects [of alcohol on prenatal] brain development opens new diagnostic opportunities for fetal neuroradiology, allowing early postnatal support programs in these cases and stimulating the discussion of alcohol prevention during pregnancy to promote public health," the group noted. (auntminnieeurope.com)
  • These may include genetic factors, infections, traumatic or toxic exposure or nutritional factors which result in perinatal or postnatal damage. (who.int)
  • The progeny (F1 generation) continued their exposure past puberty and breeding, through gestation of the F1 females, and up to postnatal day (PND) 6 of the F2 litters. (europa.eu)
  • At least in experimental animals, genetical y modified strains, because on the differential effects of a wide greater susceptibility to chemical in these species the interval between variety of carcinogens in humans at carcinogens in utero and during birth and sexual maturity is only a different stages of life, including var early postnatal life is usual y man few weeks. (who.int)
  • The association between exposure to secondhand smoke (SHS) during pregnancy and a child's neurodevelopment has not been established yet. (biomedcentral.com)
  • We quantified urine cotinine concentrations in mothers once from 12th to 20th gestational weeks and excluded those whose urine cotinine levels exceeded 42.7 ng/ml to represent SHS exposure in early pregnancy. (biomedcentral.com)
  • Maternal exposure to SHS during pregnancy may result in delayed MDI in early childhood. (biomedcentral.com)
  • Metabolic gene polymorphisms might modify the effect of toxins on the outcome of pregnancy and development afterwards. (biomedcentral.com)
  • Because a sizable population of young, married women were supplied with this water in their homes, concern has been raised about the potential adverse effects of VOCs on pregnancy outcomes. (cdc.gov)
  • We assessed the sex-specific association between residential PM 2.5 exposure during pregnancy and the methylation level of CpG loci mapping to the IGF2 / H19 cluster, and identified prenatal vulnerability by investigating susceptible time windows of exposure. (biomedcentral.com)
  • In this study, we assessed the association between maternal PM 2.5 exposure during pregnancy and the DNA methylation level specific to IGF2/H19 gene cluster in cord blood collected at birth. (biomedcentral.com)
  • Other considerations include pregnancy in the HCW and exposure to virus known or suspected to be resistant to antiretroviral drugs. (cdc.gov)
  • Objective: the aim of this study was to identify neonatal repercussions of exposure to crack during pregnancy, according to the clinical practices of the doctors and nurses and to analyze these patients' care protocols. (bvsalud.org)
  • This problem becomes even more available explains drug addiction as producing serious in the case of pregnancy, as exposure of a state of maladaptation, resulting in significant these patients to psychotropic drugs can have harm or suffering, for both mother and child(3). (bvsalud.org)
  • Pregnant women exposed to anxiety throughout her pregnancy is exposed to greater risks of preterm birth as well as a delayed prenatal growth rate. (wowessays.com)
  • Existing literature primarily focuses on the effects of psychological distress during pregnancy, emphasizing adverse child outcomes. (frontiersin.org)
  • To elucidate the differential associations of maternal psychological distress and positive mental health during pregnancy with child outcomes, we conducted a systematic literature search and random-effects meta-analyses on studies investigating the associations of prenatal maternal mental health with child socioemotional development. (frontiersin.org)
  • This study has a large number of participants, and addresses an important question of whether a mother's exposure to phthalates in pregnancy is associated with language delay in the child," Kelly Ferguson, PhD, MPH, a scientist from the National Institute of Environmental Health Sciences who was not involved in the study, told Healthline. (healthline.com)
  • Alcohol use during pregnancy exposes fetuses to fetal alcohol spectrum disorders, which can cause learning disabilities, behavioral problems, or speech and language delays, according to the investigators. (auntminnieeurope.com)
  • Unfortunately, many pregnant women are unaware of the influence of alcohol on the fetus during pregnancy," Kienast said in a 22 November RSNA statement. (auntminnieeurope.com)
  • Some, but not all, children born after toxic exposures during pregnancy grow to have developmental and behavioral challenges. (mrn.org)
  • While the cause of NAS is exposure to substances, not all infants born to people using substances during pregnancy will develop NAS. (medicalnewstoday.com)
  • The current study examined associations of mindfulness facets during pregnancy with toddler's social-emotional development and behavior problems, as well as potentially mediating effects of maternal mental health. (researchgate.net)
  • Pregnancy distress mediated the association between maternal non-judging skills during pregnancy and child externalizing problem behavior, but no other mediating effects were found. (researchgate.net)
  • Due to the relatively high number of tests that were conducted, the mediating effect of pregnancy distress must be interpreted with caution. (researchgate.net)
  • In a study of the effect on infant health of a mother's experience of adversity in childhood by researcher Deborah Kim and colleagues, both adversity in childhood (such as physical abuse or the loss of a parent) and stress during pregnancy were associated with low infant birth weight and lower gestational age at birth . (bipolarnews.org)
  • Fetal Alcohol Spectrum Disorder (FASD) is a diagnostic term that is used to describe the diverse and lifelong developmental effects that exposure to alcohol during pregnancy has on the developing fetus (Cook et al. (aifs.gov.au)
  • [ 4 ] Unfortunately, it has been reported that 30% of pregnant women are not tested for HIV during pregnancy, and another 15-20% receive no or minimal prenatal care, thereby allowing for potential newborn transmission. (medscape.com)
  • The Antiretroviral Pregnancy Registry, where clinicians should report cases of exposure to antiviral therapy in pregnancy, contains approximately 18,000 reported exposures and notes no increase in the congenital malformation rate with exposure to antiretroviral medications, even in the first trimester, with the exception of didanosine and nelfinavir . (medscape.com)
  • The influence of environmental chemicals on breast cancer risk may be greater during several windows of susceptibility (WOS) in a woman's life, including prenatal development, puberty, pregnancy, and the menopausal transition. (biomedcentral.com)
  • These time intervals represent windows of susceptibility (WOS) and coincide with landmark events when a woman's breast tissue changes in structure and function including the prenatal, pubertal, pregnancy, and menopausal WOS. (biomedcentral.com)
  • Several studies have shown that zidovudine monotherapy had no negative effect on pregnancy. (medscape.com)
  • We explored the association between prenatal exposure to SHS and neurodevelopment at 24 months of age considering genetic polymorphism and breastfeeding in 720 mothers and their offspring enrolled in the Korean multicenter birth cohort study (Mothers and Children Environmental Health, MOCEH). (biomedcentral.com)
  • Prenatal alcohol exposure affects a wide range of genetic and neurodevelopmental functions influencing every aspect of the developing embryo and fetus' physical and neurological development. (aifs.gov.au)
  • Canada's current FASD diagnostic guidelines include an at-risk designation, intended for people with confirmed prenatal alcohol exposure and neurodevelopmental delays, but who don't quite meet the criteria for an FASD diagnosis. (fasdontario.ca)
  • The study, known as the MONEAD (Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs), has been ongoing for two decades and focuses on the impact of anti-seizure medications on both mothers and their children. (hcn.health)
  • High dosages of levetiracetam in the third trimester were correlated with some adverse neurodevelopmental effects, warranting careful monitoring. (hcn.health)
  • The long-term effects of neonatal abstinence syndrome (NAS) are not well known, but some research suggests it can continue to affect a child into adolescence. (medicalnewstoday.com)
  • NAS - sometimes known as neonatal opioid withdrawal syndrome (NOWS) - is a group of physical and behavioral symptoms that can occur in newborns after experiencing exposure to certain substances while in the womb. (medicalnewstoday.com)
  • Disability may be developmental or acquired and may arise from prenatal damage, perinatal factors, acquired neonatal factors and early childhood factors. (who.int)
  • The American College of OBGYN states that routine ultrasound is not cost effective and does not influence neonatal outcome. (faqs.org)
  • Epigenetic tools for improved diagnosis in the prenatal and neonatal periods. (ubc.ca)
  • This study adds to a growing but inconclusive body of research that suggests that phthalate exposure might raise the risk of certain health problems in children. (healthline.com)
  • Research findings on the potential links between phthalate exposure and negative health outcomes are in many cases inconsistent - and more research is needed to study the potential effects of different phthalates on human health. (healthline.com)
  • For example, three common routes of phthalate exposure include dust, food, and personal care products. (healthline.com)
  • While previous research has linked phthalate exposure to birth defects, low sperm count, polycystic ovary disease, and early or delayed puberty, just to name a few, recent research suggests prenatal phthalate exposure may also lead to reduced IQ in children. (sott.net)
  • Harmful exposure to these environmental risks could begin in the mother's womb and affect fetal development. (biomedcentral.com)
  • There are a number of studies that examine a mother's exposure to phthalates and neurodevelopment in children, but this is the first using this outcome," she added. (healthline.com)
  • Editor's Note: This research shows that a mother's health and earlier life stressors could have an adverse effect on her child. (bipolarnews.org)
  • In addition to these neurobiological alterations mediated by epigenetic effects, there is new evidence that some epigenetic marks can be passed on to the next generation via a mother's egg or a father's sperm. (bipolarnews.org)
  • The discovery also links the gene to the mother's early prenatal vitamin use and placental oxygen levels. (ameridisability.com)
  • Ambient airborne fine particulate matter with diameter smaller than 2.5 Ī¼m, PM 2.5 , is one of the air pollution components with the strongest adverse effects on health and mortality as it can penetrate the respiratory system, circulate via bloodstream to other organs [ 9 , 10 ] and cross the maternal-fetal placental barrier [ 11 , 12 ]. (biomedcentral.com)
  • Public health officials and others concerned with appropriate actions to take at hazardous waste sites may want information on levels of exposure associated with more subtle effects in humans or animals (LOAELs) or exposure levels below which no adverse effects (NOAELs) have been observed. (cdc.gov)
  • Although there have been some recent therapeutic advances, many patients with chronic pain develop tolerance to conventional medical treatments or suffer adverse effects from widely used prescription medications, such as non-steroidal anti-inflammatory agents or opiates, that have high addictive potential (Labianca et al. (medicalmrjnshop.org)
  • Objectives During the perinatal period, women are exposed to major changes, holding possible adverse effects on psychological well-being and child development. (researchgate.net)
  • The results would provide theoretical basis to protect vulnerable population defined by birth season when exploring the adverse effects of ambient PM 2.5 in the respiratory health. (biomedcentral.com)
  • Purpose Research reveals that prenatal alcohol exposure and child trauma (i.e., abuse, neglect, sexual abuse) can have deleterious effects on child development across multiple domains. (ubbcluj.ro)
  • Left) Fetal brain post-intrauterine alcohol exposure in a fetus between 25 and 29 gestational weeks. (auntminnieeurope.com)
  • to actively educate the public about the effects of alcohol on the fetus. (auntminnieeurope.com)
  • This was true even for fetuses with mild alcohol exposure. (auntminnieeurope.com)
  • As we show in our study, even low levels of alcohol consumption can lead to structural changes in brain development and delayed brain maturation," Kienast said. (auntminnieeurope.com)
  • The prenatal effects of alcohol are one of the most common causes of mental disorders in children. (ukraineomni.org)
  • Fetal Alcohol Spectrum Disorder (FASD) is a term used to describe the wide variety of lifelong developmental effects associated with prenatal alcohol exposure. (aifs.gov.au)
  • First, it requires confirmation of prenatal exposure to alcohol. (fasdontario.ca)
  • The development of the tool is based on epigenetics-changes that happen to a gene as the result of environmental influences, such as prenatal alcohol exposure. (fasdontario.ca)
  • The idea is that this would be a quick, cost-effective way to identify children at-risk of having the disability, including situations where confirmation of prenatal alcohol exposure isn't disclosed. (fasdontario.ca)
  • This project builds on previous work supported by KBHN (then NeuroDevNet), which sampled over 200 individuals and identified several epigenetic signatures unique to those with FASD- the largest investigation of prenatal alcohol exposure effects on the human epigenome to date. (fasdontario.ca)
  • In the future, this could lead to identification of other disorders or health conditions associated with FASD, as a way for researchers to discriminate between changes resulting from alcohol exposure and those that are caused by other common risk factors or overlapping disorders. (fasdontario.ca)
  • In January 1990, CDC issued a statement on the management of HIV exposures that included considerations for zidovudine (ZDV) use for postexposure prophylaxis (PEP) (1). (cdc.gov)
  • In this mini-review, we present balanced and unbiased pre-clinical and clinical findings for the beneficial effects of CBD treatment on chronic pain and its deleterious effects on prenatal development. (medicalmrjnshop.org)
  • To the best of our knowledge, this is the first study investigating the association between prenatal PM 2.5 exposure and newborn DNA methylation of the IGF2/H19 . (biomedcentral.com)
  • From the ongoing population-based prospective ENVIRONmental influence ON AGEing in early life (ENVIR ON AGE) birth cohort [ 23 ], 199 mother-newborn (all singleton) pairs that were recruited between July 2014 and June 2015 were included. (biomedcentral.com)
  • 3. List three ways that maternal anxiety can influence the birth process and the newborn. (wowessays.com)
  • When age-specific associations were examined, the elevated risks related to SHS exposure in utero or during infancy were mostly confined to early childhood for asthma and rhinitis, whereas the excess risk of eczema appeared greatest at later ages. (lu.se)
  • CONCLUSIONS: Our findings indicate that early SHS exposure, in utero or during infancy, influences the development of allergic disease up to adolescence. (lu.se)
  • Alterations in methylation of the imprinted IGF2/H19 cluster might be a potential mechanism underlying the association between in utero PM 2.5 exposure and fetal growth, as maternal residential PM 2.5 has been reported to alter their expression [ 22 ]. (biomedcentral.com)
  • Developmental delay resulting from valproate exposure can cause an average loss of 9 IQ points compared to children exposed to other anticonvulsant drugs in utero . (bipolarnews.org)
  • Environmental contamination (potential exposure): the exposure source and how the contaminant disperses in the environment. (cdc.gov)
  • Epigenetic marks generated within germ cells as a result of environmental influences throughout life can also shape future generations long before conception occurs. (nih.gov)
  • These results are consistent with our model and provide further support for the hypothesis that concurrent genetic vulnerability and environmental OP exposure may possibly contribute to autism pathogenesis in a sizable subgroup of North American individuals. (nature.com)
  • investigators planning research in this area must look to other studies of the impact of chronic environmental trauma on children, including the effects of war and child maltreatment. (ubbcluj.ro)
  • Some researchers hypothesize that genetic predispositions combined with environmental stressors (eg, virus exposure or birth trauma) result in brain deposition of amyloid and disruption of synaptic transmissions, possibly involving interleukin-1 (IL-1) or beta-endorphins. (medscape.com)
  • The combined effects of genotypes and environmental factors together on phenotypic characteristics. (lookformedical.com)
  • Despite the plausible heightened mechanistic influences of environmental chemicals on breast cancer risk during time periods of change in the mammary gland's structure and function, most human studies of environmental chemicals are not focused on specific WOS. (biomedcentral.com)
  • This article reviews studies conducted over the past few decades that have specifically addressed the effect of environmental chemicals and metals on breast cancer risk during at least one of these WOS. (biomedcentral.com)
  • By focusing on environmental chemical exposure during specific WOS, scientists and their community partners may identify when prevention efforts are likely to be most effective. (biomedcentral.com)
  • In 2003, the National Institute for Environmental Health Sciences (NIEHS) initiated the Breast Cancer and the Environment Research Program (BCERP) with support from the National Cancer Institute (NCI) to specifically examine whether environmental exposures during the pubertal WOS affect the timing of puberty, a risk factor for breast cancer. (biomedcentral.com)
  • Furthermore, birth season which is frequently applied as a proxy for environmental exposure in early life may influence the health outcome in the later life. (biomedcentral.com)
  • However, in some cases, exposure to environmental factors such as air pollution and pesticides can lead to excessive oxidative stress. (ameridisability.com)
  • But excessive oxidative stress may come from environmental exposures linked to ASD such as air pollution, pesticides, maternal obesity and inflammation," LaSalle said. (ameridisability.com)
  • These data are discussed in terms of three exposure periods: acute (14 days or less), intermediate (15-364 days), and chronic (365 days or more). (cdc.gov)
  • These time windows are considered as specific periods of susceptibility for breast cancer because significant structural and functional changes occur in the mammary gland, as well as alterations in the mammary micro-environment and hormone signaling that may influence risk. (biomedcentral.com)
  • As genetic factors and events during prenatal life may strongly influence developmental changes, genetics and prenatal development usually form a part of the study of child development. (wikipedia.org)
  • Whether an exposure could lead to an adverse health outcome depends on the characteristics of exposure and the exposed population (e.g., developmental stage, existing disease state, genetic factors) that could make them more susceptible to site-related exposures. (cdc.gov)
  • We investigated the association between cord blood DNA methylation status of the IGF2/H19 gene cluster and maternal fine particulate matter exposure during fetal life. (biomedcentral.com)
  • It is well known that SHS exposure brings about almost the same adverse health outcomes as active smoking [ 3 ]. (biomedcentral.com)
  • Our analyses, comprising 74 studies with 321,966 mother-child dyads across 21 countries, revealed significant associations of prenatal psychological distress with both adverse and positive child socioemotional outcomes. (frontiersin.org)
  • Notably, the effect sizes for the association of psychological distress with positive child outcomes were smaller compared to adverse outcomes. (frontiersin.org)
  • Positive prenatal mental health, on the other hand, was significantly associated with positive socioemotional outcomes but not adverse outcomes. (frontiersin.org)
  • The findings underscore the importance of considering the positive spectrum of maternal mental health and developmental outcomes to enhance our understanding of prenatal influences on child development. (frontiersin.org)
  • It may also influence future health outcomes. (ameridisability.com)
  • Conclusion Maternal interpersonal trauma exposures can negatively impact child social-emotional development, acting in part through maternal psychosocial factors. (ubbcluj.ro)
  • In pregnant women, exposure of the fetus to the anticonvulsant valproate (VPA or Depakote) is associated with a variety of serious problems that include congenital malformations, developmental delay, and autism. (bipolarnews.org)
  • According to a new study published in JAMA Pediatrics, prenatal exposure to certain types of phthalates might put children at increased risk of delayed language development. (healthline.com)
  • In absence of data to the contrary, assume that the toxicokinetics is the same in animals and humans under similar exposure conditions. (cdc.gov)
  • Animals that have similar toxicokinetics to humans likely serve as good predictors of harmful effects in humans. (cdc.gov)
  • Understanding the basic or specific biologic changes that ultimately lead to clinical disease in a test animal can help health assessors determine how well animal models might predict the similar adverse effect in humans. (cdc.gov)
  • Studies in experimental incidence and multiplicity of tumours to Wilms tumour in humans - in the animals increase and the latency period de adult rat after perinatal exposure to a creases with increasing dose. (who.int)
  • This section provides an overview of how to examine factors that influence whether an exposure to a contaminant could produce harmful health effects and how these factors weigh into your public health conclusions. (cdc.gov)
  • The present study aimed, therefore, to examine the influence of residential history, in areas with and without food production, on breast cancer incidence in relation to the dietary effects of World War II. (nature.com)
  • The results of our study provided evidence that prenatal PM 2.5 exposure is associated with DNA methylation in newborns' IGF2/H19 . (biomedcentral.com)
  • These effects of choline are correlated with modifications in histone and DNA methylation in brain, and with alterations in the expression of genes that encode proteins important for learning and memory processing, suggesting a possible epigenomic mechanism of action. (mdpi.com)
  • This cohort study examined the relationship between VOC exposure and fetal growth retardation (measured as SGA and decreased MBW) and preterm delivery in three groups with different exposures to contaminated drinking water and in an unexposed comparison population. (cdc.gov)
  • for Economic Cooperation and Development, pesticide exposure. (cdc.gov)
  • Since its publication in 1979, Bronfenbrenner's major statement of this theory, The Ecology of Human Development, has had widespread influence on the way psychologists and others approach the study of human beings and their environments. (wikipedia.org)
  • This information, along with data on ZDV efficacy in preventing perinatal transmission (3) and evidence that PEP prevented or ameliorated retroviral infection in some studies in animals (4), prompted a Public Health Service (PHS) interagency working group *, with expert consultation (5), in June 1996 to issue provisional recommendations for PEP for HCWs after occupational HIV exposure (6). (cdc.gov)
  • In bioassays for ment of nephroblastomas - embryo tentially carcinogenic exposures. (who.int)
  • Prenatal exposure to PM 2.5 may have even life-long consequences as, according to the Developmental Origins of Health and Diseases (DOHaD) theory, perturbations in the intrauterine environment are involved in the development of disease in later life [ 21 ]. (biomedcentral.com)
  • Becker also found that stress in early life or even during the prenatal period can increase vulnerability to drug use and abuse. (sfn.org)
  • There's been some suggestion that prenatal exposure may also be associated with obesity or changes in later-life metabolism - so risk of things like high cholesterol or insulin resistance," he added. (healthline.com)
  • The emerging science shows how life experiences shape nervous systems patterns of regulation early in life and influence long-term health. (chronicillnesstraumastudies.com)
  • Thus, either directly or indirectly, parents' adverse life experiences can influence the health of their offspring. (bipolarnews.org)
  • Recent conceptualisation of FASD is moving away from a medical narrative towards a more holistic, person-centred understanding, including the effects of FASD over the life course (Dowse, Dillon-Savage, Dew, & Strnadova, 2020). (aifs.gov.au)
  • The external elements and conditions which surround, influence, and affect the life and development of an organism or population. (lookformedical.com)
  • The aggregate of social and cultural institutions, forms, patterns, and processes that influence the life of an individual or community. (lookformedical.com)
  • However, few evidence was available on the effect of exposure to ambient PM 2.5 on the years of life lost (YLL) from respiratory diseases in the elderly. (biomedcentral.com)
  • Birth season which reflects the early-life PM 2.5 exposure level that may influence the lung development has a potential effect on the disease burden of respiratory diseases related to ambient PM 2.5 exposure in later life. (biomedcentral.com)
  • In addition, studies exploring the effect of ambient PM 2.5 exposure on the years of life lost (YLL) from respiratory diseases are scarce. (biomedcentral.com)
  • These factors in the early life may influence the health outcome in later life. (biomedcentral.com)
  • It has been suggested that breast cancer incidence is particularly sensitive to influences early in life. (nature.com)
  • This chapter exposed adults, with a shorter laten onal solid tumours, are observed as summarizes the literature that docu cy period from the time of exposure tumours of adult life in conventional ments this high susceptibility of the to the carcinogen until the appear rodents. (who.int)
  • Most experimental studies of the predominant results of earlylife do not develop in rats exposed to the carcinogenesis during prenatal life exposure are what would be expect same carcinogen during adult life and infancy have been conducted ed from a higher effective dose to the (Diwan and Rice, 1995 ). (who.int)
  • This effect might be modified by genetic polymorphism and breastfeeding behavior. (biomedcentral.com)
  • They're not always consistent, but some studies do suggest that prenatal exposure to some of these phthalates is associated with decreased IQ, as well as changes in behavior," Joseph Braun, PhD, an assistant professor of epidemiology at the School of Public Health at Brown University, told Healthline. (healthline.com)
  • Its presence in the body can lead to toxic effects, regardless of age, gender, or exposure pathway. (cdc.gov)
  • A contaminant will produce adverse or toxic effects only if it (or its metabolites) reaches specific sites in the body at a dose and over a duration sufficient to produce an adverse non-cancer effect. (cdc.gov)
  • Researchers found evidence that kids have language delay if their mothers were exposed to phthalates. (healthline.com)
  • Children who were born to mothers with high levels of dibutyl phthalate (DBP) and butyl benzyl phthalate (BBP) in their urine were up to 30 percent more likely to experience language delay, compared to those born to mothers with lower levels of DBP and BBP. (healthline.com)
  • Some research suggests that male children who are born to mothers with high levels of exposure to certain phthalates are more likely than others to have undescended testicles. (healthline.com)
  • However, it also underscores the need for careful monitoring of medication dosages, particularly in the third trimester, and for addressing maternal mental health as a part of comprehensive prenatal care. (hcn.health)
  • Exposure occurs through an exposure pathway between the contaminant in the physical environment and the exposed person. (cdc.gov)
  • The toxic effect of a contaminant will be influenced by its toxicokinetic or pharmacokinetic properties (e.g., rates of absorption, distribution, metabolism, and elimination ). (cdc.gov)
  • Ukrainian Teratology Information System (UTIS) - a site in Ukrainian about the negative prenatal effects of medications and other teratogenic factors on children's health. (ukraineomni.org)
  • Further research is needed to assess the long-term effects of less commonly used anti-seizure medications. (hcn.health)
  • Research suggests that the long-term effects of being born with NAS may affect a person throughout infancy and childhood and into adolescence. (medicalnewstoday.com)
  • Many factors influence the accumulation of bone mineral during childhood and adolescence, including heredity, gender, diet, physical activity, endocrine status and sporadic risk factors such as cigarette smoking. (ox.ac.uk)
  • As depicted in the figure below, multiple factors influence whether an exposure could result in harmful health effects, as well as the type and severity of those health effects. (cdc.gov)
  • Beyond depression, fetal development is intricately shaped by a diverse spectrum of prenatal mental health factors. (frontiersin.org)
  • Little is known about theā€¦ The long-term consequences of trauma exposure, such as substance abuse, incarceration, and co-occurring psychiatric problems are discussed along with the importance of recognizing protective factors, examining resiliency, and identifying empirically based treatment modalities to help alleviate symptoms of trauma survivors. (ubbcluj.ro)
  • Homocysteine levels, however, are not a highly specific indicator of folate status because they can be influenced by other factors, including kidney dysfunction and deficiencies of vitamin B12 and other micronutrients [ 1 , 3 , 9 , 10 ]. (nih.gov)
  • Physical surroundings or conditions of a hospital or other health facility and influence of these factors on patients and staff. (lookformedical.com)
  • November 24, 2022 -- MRI reveals how women's prenatal drinking -- even in low or moderate amounts -- has a negative effect on fetal brain development, according to Austrian research to be presented at RSNA 2022 in Chicago. (auntminnieeurope.com)
  • Chemical carcinogens that reach contribute to carcinogenic effects in when organogenesis starts. (who.int)
  • Ross and colleagues suggest that pre- and post-natal choline supplementation may be able to reverse the effects of maternal anxiety on infants. (bipolarnews.org)
  • They do not report that he had had any language delays. (medscape.com)
  • The association of maternal hypothyroidism with childhood ADHD was influenced by timing of diagnosis. (nih.gov)
  • Therefore, SHS exposure should be considered a modifiable risk factor for delayed neurodevelopment and cognitive impairment in children. (biomedcentral.com)
  • A potential link has also been identified between childhood exposure to phthalates and the development of allergic diseases, such as food allergy, eczema, and asthma. (healthline.com)
  • The Role of Traffic-Related Pollution in PM-Health Effects Associations Among Inner-City Children With Asthma. (epa.gov)
  • Although effects of prenatal exposure to SHS on early neurodevelopment vary among studies, they remain significant issues. (biomedcentral.com)
  • The points in the figures showing no-observed-adverse-effect levels (NOAELs) or lowest- observed-adverse-effect levels (LOAELs) reflect the actual doses (levels of exposure) used in the studies. (cdc.gov)
  • Previous studies have shown PFAS exposure to be associated with a reduced immune response. (cdc.gov)
  • The long time from exposure to potentially harmful chemicals until breast cancer occurrence poses challenges for designing etiologic studies and for implementing successful prevention programs. (biomedcentral.com)
  • SAN DIEGO, November 5, 2007 - Females seem to be unequally disposed to the harmful effects of stress and to addiction compared with males. (sfn.org)
  • Lead (Pb) Toxicity: What Are Possible Health Effects from Lead Exposure? (cdc.gov)
  • The sections below describe specific health effects for population groups and major organ systems and functions. (cdc.gov)
  • Exposure to active smoking and secondhand smoke (SHS) causes health concern. (biomedcentral.com)
  • When available, health assessors can refer to the toxicokinetic data analysis included in the MRL summary in the Toxicological Profile, which presents methods for extrapolating animal data to human exposure. (cdc.gov)
  • For example, EPA's IEUBK Model external icon is a type of PBPK model that ATSDR health assessors should use when evaluating childhood exposure to lead in soil. (cdc.gov)
  • The impact of prenatal maternal mental health on offspring socioemotional development is substantial and enduring. (frontiersin.org)
  • This meta-analysis highlights the independence of negative and positive prenatal mental health constructs and their distinct relationships with child socioemotional development. (frontiersin.org)
  • Furthermore, it is worth noting that the ramifications of prenatal mental health on offspring persist even when accounting for postpartum maternal mental well-being ( 6 , 7 ). (frontiersin.org)
  • As such, it becomes imperative to explore both the domains of negative and positive mental health to understand holistically how maternal mental health influences offspring socioemotional development. (frontiersin.org)
  • The distinction between 'less serious' effects and 'serious' effects is considered to be important because it helps the users of the profiles to identify levels of exposure at which major health effects start to appear. (cdc.gov)
  • LOAELs or NOAELs should also help in determining whether or not the effects vary with dose and/or duration, and place into perspective the possible significance of these effects to human health. (cdc.gov)
  • Nevertheless, the modification effect of birth season on the relationship of PM 2.5 exposure and respiratory health need to be explored. (biomedcentral.com)
  • Although the modifications of traditional demographic characteristics in the health effects of PM 2.5 exposure are frequently analyzed, the impact of birth season is rarely taken into consideration. (biomedcentral.com)
  • Disability Data because of the strong effect of age on health. (cdc.gov)
  • Absorbed dose: how much of a toxicant is absorbed after an exposure occurs. (cdc.gov)
  • Biologic changes: the chemical changes causing damage to tissues following a toxic exposure and an absorbed dose. (cdc.gov)
  • Model inputs include the exposure dose and model parameters, such as tissue volumes, blood flow rates, partition coefficients, and metabolic rates. (cdc.gov)
  • The effects appear to be in part dose-related and dependent on the intensity of combination treatment with other agents. (bipolarnews.org)
  • Similarly, destruction of neonatally abundant pluripotent stem cells would likely have a more pervasive outcome than destruction of The value of incorporating immunologic appeared more severe and/or persistent when single lineages or differentiated cells that pre- data for the toxicologic assessment of drugs, the exposure occurred perinatally when com- dominate in adults. (cdc.gov)
  • Note on language: When I first posted the questions for the prenatal testing FAQs, I used the term "birth defects" (except for question 7 of the Prenatal Testing Overview FAQ). (faqs.org)
  • Occupational exposures should be considered urgent medical concerns to ensure timely administration of PEP. (cdc.gov)
  • The major congenital malformations that can result from valproate exposure include spina bifida, which results in lifelong paralysis of the child's lower limbs. (bipolarnews.org)
  • Exercise can delay or reduce the risks for the development of dementia in the aging population thereby improving cognitive performance with age. (wowessays.com)
  • Medical References on Benzodiazepines, side-effects and risks A Aarskog D. Association between Maternal Intake of Diazepam and Oral Clefts. (benzo.org.uk)
  • 2003). However, increasing access to cannabis derived products especially CBD partly because of their approval for recreational and medicinal use in the United States poses risks with inadvertant side-effects from overuse, contamination with adulterants in preparation or harsh chemicals in the plant cultivation, and its teratogenicity in the offspring of users (Bonn-Miller et al. (medicalmrjnshop.org)