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  • anti-inflammatory effect
  • Finally, VNS increased STAT3 phosphorylation and inhibited NF-κB activation in mesenteric arteries, and these effects were abolished by α7nAChR shRNA treatment, indicating VNS-mediated anti-inflammatory effect mainly involved α7nAChR. (springer.com)
  • leukocyte
  • Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. (nih.gov)
  • Leukocyte infiltration and pro-inflammatory gene expression also contribute to stroke damage. (nih.gov)
  • Thus, the specific novel bioactive docosanoids generated in vivo counteract leukocyte-mediated injury as well as pro-inflammatory gene induction. (nih.gov)
  • Human leukocyte/endothelial cell interactions and mitochondrial dysfunction in type 2 diabetic patients and their association with silent myocardial ischemia. (biomedsearch.com)
  • OBJECTIVE: Diabetes is associated with oxidative stress and increased mortality, but a possible correlation between leukocyte-endothelium interactions, oxidative stress, and silent myocardial ischemia (SMI) is yet to be confirmed. (biomedsearch.com)
  • commensal
  • Interestingly, the depletion of gut commensal flora results in a significant reduction in inflammatory cell recruitment to the lung following IR. (jimmunol.org)
  • retina
  • These data suggest that NSAIDs (aspirin, sulfasalazine or sulindac) can be the potential drugs to protect the retina neurons injured by ischemia. (arvojournals.org)
  • significantly
  • Ischemia plus diabetes did not increase these findings significantly. (lu.se)
  • Ghrelin administration prior to blood reperfusion significantly decreased serum concentrations of cTn-I versus animals subjected I/R alone, with a significantly attenuated VCAM-1 expression in I/R animals pre-treated with ghrelin. (ajbm.net)