Meningitis is a clinical syndrome characterized by inflammation of the meninges. (medscape.com)
Meningitis refers to the life-threatening inflammation of the meninges-the structures found at the vertebral canal and skull enclosing the brain and spinal cord. (nursetogether.com)
Meningitis happens when the membrane covering the brain and the spinal cord, called the meninges, becomes infected and swollen or inflamed. (rch.org.au)
"The term 'meningitis' relates to inflammations of the meninges - membranes that envelop the central nervous system, i.e. the brain and spinal cord. (pasteur.fr)
Most frequently, the illness can result in inflammation of the meninges of the brain (meningitis) and a serious bloodstream infection (septicemia/meningococcemia). (nvic.org)
Meningitis is an infection that causes inflammation of the meninges, which is a layer of tissues that cover the brain and spinal cord. (unr.edu)
Several organisms such as bacteria, viruses, and fungi can cause inflammation of the membranes lining the brain and spinal cord (the meninges), resulting in the illness " meningitis . (healthnews.com)
However, the term meningitis is usually used to refer to infection that affects mainly the meninges, and encephalitis is usually used to refer to infection that affects mainly the brain. (merckmanuals.com)
Meningitis is inflammation of the meninges, which are membranes that surround the spinal cord. (manchesterneurophysio.co.uk)
Meningitis is a disease caused by the inflammation of the protective membranes, called meninges, that cover the brain and spinal cord. (keyt.com)
Meningitis is an inflammation of the meninges (which protects the nervous system), the protective layer surrounding the brain and spinal cord. (differencebetween.net)
Written By: Andrea Brabant - FM PGY1 - NWT Expert Review By: Dr Katherine Breen, ER Physician NWT Meningitis is defined as inflammation of the meninges, the membranes covering the brain and spinal cord. (tunein.com)
Meningitis is an infection, and or an inflammation of the meninges, which is the cover of your brain and spinal cord," said Dr. Christian Montagano. (myfox8.com)
For example, a patient presenting to a clinician with a combination of headache, fever, vomiting and neck stiffness has a syndrome that suggests meningitis (inflammation of the covering of the brain- the meninges- usually caused by infection). (gresham.ac.uk)
Meningitis is the term used to describe the Enteroviruses are responsible for approxima- inflammation of the brainmeninges, and it is the tely 90% of cases of aseptic meningitis. (bvsalud.org)
Pediatric bacterial meningitis is a life-threatening illness that results from bacterial infection of the meninges and leaves some survivors with significant sequelae. (medscape.com)
Spinal10
The three membranes that cover the brain and spinal cord (singular: meninx). (rxlist.com)
The nerves in the spinal cord are surrounded by several thin tissues, called meninges, which provide cushioning and protection. (medicalnewstoday.com)
The condition should then be confirmed by performing a lumbar puncture and if that shows inflammation in the cerebro-spinal fluid obtained then the diagnosis is confirmed. (gresham.ac.uk)
Infection5
This is why the presence of an infection in your meninges is often enough to cause both neck pain and stiffness. (healthline.com)
This test will show any signs of inflammation and whether the infection is due to a virus or bacteria. (kidshealth.org)
Inflammation of the meninges caused by a bacterial or viral infection and characterized by high fever, severe headache, and stiff neck or back muscles. (cdc.gov)
There are six known fungi that can penetrate the meninges, including Candida albicans , the most common cause of systemic yeast infection. (yeastinfectionadvisor.com)
The inflammation of membranes at the base of your brain can cause this symptom, as well as severe headaches and cognitive difficulties. (healthline.com)
They also might give steroids to ease inflammation in the brain and IV fluids to replace those lost due to fever, sweating, vomiting, and poor appetite. (kidshealth.org)
The other type of inflammation is a slow accumulation of T-cells and B-cells in the absence of major blood brain barrier damage in the connective tissue spaces of the brain, such as the meninges and the large perivascular Virchow Robin spaces, where they may form aggregates or in most severe cases structures in part resembling tertiary lymph follicles. (frontiersin.org)
Immune cells in the meninges come from bone marrow in the skull and migrate to the brain through special channels without passing through the blood. (neurosciencenews.com)
Since BAFF [B cell-activating factor of the tumor necrosis factor (TNF) family] promotes B cell survival and maturation and is a co-stimulator of T cells, we used anti-BAFF antibody 10F4 as a BAFF antagonist to study its effect on meningeal inflammation and adjacent brain regions in a relapsing-remitting PLP-EAE (rr-EAE) model of multiple sclerosis in SJL/J mice. (bvsalud.org)
We also performed histopathological analysis in brain sections of these mice to study the effects of the BAFF antagonist on leptomeningeal inflammation, and hippocampal and cortical neurons and synapses. (bvsalud.org)
Meningeal inflammation3
We performed ultra-high field (11.7 T) MRI to identify areas of meningeal inflammation and track them over time in both treatment groups. (bvsalud.org)
We observed that BAFF antagonist treatment reduced B cells, T cells, and myeloid cells in regions of meningeal inflammation. (bvsalud.org)
Additionally, we noted that BAFF treatment protected against EAE-induced synaptic and neuronal loss in the adjacent cortex and in the CA1, CA3, and dentate gyrus regions of the hippocampus likely due to its effects on meningeal inflammation. (bvsalud.org)
Bone marrow1
Channels connecting the skull bone marrow and the meninges have recently been discovered as a path for immune cell and molecule trafficking. (bvsalud.org)
This type of inflammation is associated with the formation of subpial demyelinated lesions in the cerebral and cerebellar cortex, with slow expansion of pre-existing lesions in the white matter and with diffuse neurodegeneration in the normal appearing white or gray matter. (frontiersin.org)
The first type of inflammation dominates in acute and relapsing MS. The second type of inflammation is already present in early stages of MS, but gradually increases with disease duration and patient age. (frontiersin.org)
Peripheral1
Additionally, CGRP might be important in processes such as control of fetoplacental vascular tone, regulation of calcium metabolism and insulin secretion, acetylcholine receptor synthesis, peripheral nerve regeneration, and neurogenic inflammation. (bachem.com)
In mice injected with α-synuclein (α-syn) preformed fibrils, we showed that the emergence of α-syn pathology was followed by delayed meningeal lymphatic drainage, loss of tight junctions among meningeal lymphatic endothelial cells and increased inflammation of the meninges. (lu.se)
MRI is the most sensitive imaging modality, because the presence and extent of inflammatory changes in the meninges, as well as complications, can be detected. (medscape.com)
Inflammation of the liver caused by one of at least seven immunologically unrelated viruses. (cdc.gov)
Blood1
B) Inflammation of the meninges and dilated blood vessels (arrows). (cdc.gov)
Disease1
Numerous studies have linked the presence of leptomeningeal inflammation to a more severe disease course, underscoring its potential importance as a driver of gray matter pathology in MS. The major components of leptomeningeal inflammation include T cells, B cells, macrophages, follicular dendritic cells, and plasma cells. (bvsalud.org)