Infects the bacterium escherichia coli bacteriophages. Medical search. Frequent questions

Enterobacteria phage T6 is a bacteriophage strain that infects Escherichia coli bacteria. (wikipedia.org)
It was one bacteriophage that was used as a model system in the 1950s in exploring the methods viruses replicate, along with the other T-even bacteriophages (which build up virus species Escherichia virus T4, a member of genus T4virus according to ICTV nomenclature): Enterobacteria phage T2, Enterobacteria phage T4 and Enterobacteria phage T2. (wikipedia.org)
In this opinion piece I review current research on bacteria-phage AC in in vitro and natural populations of microbes. (nih.gov)
Almost one in seven of the research samples contained bacteriophages, and one contained a phage that had not been previously identified. (medscape.com)
By mixing the E. coli phage PHH01 with motile B. cereus in a flow cell, phage reached and infected the E. coli in the submerged biofilm more effectively that in the absence of B. cereus . (asmblog.org)
In addition, when mixed with the phage, B. cereus colonized the preformed E. coli biofilm more effectively than in the absence of phage. (asmblog.org)
The increase in transparency indicated that the bacteria had burst open, a process known as lysis, but it only happened in the liquid containing the phage without the transposon. (nih.gov)
These viruses specifically infect bacteria, and therefore, represent a viable alternative against MDR bacteria, Phage therapy could also help avoid side-effects like dysbiosis (the disturbance of our own body's "good bacteria" by antibiotics), and is ecologically friendly. (eurekalert.org)
Nanotechnology has now emerged as a viable adjunct to phage therapy, and this review, which appeared online on 4 January 2023, and was published in Volume 5 of the Biodesign Research journal on 16 January 2023 , aims to gather research on biosensors and antibiotic therapy that employs both nanoparticles (NPs) and bacteriophages to detect and kill or deactivate bacteria. (eurekalert.org)
This paper describes a new method to detect the interaction between bacteria and phage in a sensitive and quantitative way, using the nanomechanical motion of bacteria adhered to a microcantilever surface. (biofisica.info)
Due to a renewed interest in phage therapies, development of rapid and specific detection methods for bacteria/bacteriophage interaction are gaining attention for proper diagnosis and treatment. (biofisica.info)
In the 1940s, Max Delbruck encouraged the phage group at Cold Spring Harbor to concentrate their research on seven specific bacteriophages (T1-T7), so that they could readily compare results. (nih.gov)
For the future, the researchers state they are now working on phage cocktails combining multiple types of bacteriophages and/or antibiotics with the particles to inhibit resistance. (health-innovations.org)
Covalently closed circular DNA from M. lysodeikticus cells infected with phage N1. (microbiologyresearch.org)
In order to remove some of these obstacles, Jérémie Guedj's research team at Inserm, in collaboration with Laurent Debarbieux's team at Institut Pasteur, has developed a new mathematical model to better define the interactions between bacteriophages and pathogenic Escherichia coli bacteria in animals and to identify the key parameters that influence the efficacy of phage therapy. (inserm.fr)
The quantities of bacteria and bacteriophages thus measured over time helped to feed the mathematical model and test which were the most important parameters for effective phage therapy. (inserm.fr)
In the animal model, the phage therapy administered intravenously was therefore less effective in comparison with the intratracheal route because fewer bacteriophages were reaching the lungs. (inserm.fr)
They investigated the susceptibility of 64 Staphylococcaceae bacteria strains to bacteriophage ISP, a potential phage therapy. (ed.ac.uk)
The phenomenon by which a temperate phage incorporates itself into the DNA of a bacterial host, establishing a kind of symbiotic relation between PROPHAGE and bacterium which results in the perpetuation of the prophage in all the descendants of the bacterium. (lookformedical.com)
Upon induction (VIRUS ACTIVATION) by various agents, such as ultraviolet radiation, the phage is released, which then becomes virulent and lyses the bacterium. (lookformedical.com)
Bacteriophages whose genetic material is RNA, which is single-stranded in all except the Pseudomonas phage phi 6 (BACTERIOPHAGE PHI 6). (lookformedical.com)
BACTERIOPHAGE T4), and T6, and the phage T5 are called "autonomously virulent" because they cause cessation of all bacterial metabolism on infection. (lookformedical.com)
A frequently encountered Pseudomonas phage is BACTERIOPHAGE PHI 6. (lookformedical.com)
Each species of phage infects only one particular type or strain of bacteria. (sciena.ch)
The method also has another advantage: it allows physicians to predict which patients are likely to respond particularly well to a tailored phage therapy, as the strength of the light signal produced in the assay already indicates how efficient the phages are in attacking the bacterium - the more the sample glows, the better the bacterium will respond to the therapy. (sciena.ch)
functional analysis of the lysis genes of staphylococcus aureus phage p68 in escherichia coli. (liverpool.ac.uk)

pR444_A is found in some extraintestinal pathogenic E. coli (ExPEC) strains. (cdc.gov)
Many HUS-associated STEC strains possess a chromosomal pathogenicity island, defined as the locus of enterocyte effacement (LEE), which is associated with the attaching and effacing lesions ( 8 ) described in enteropathogenic E. coli ( 9 ), or possess the genetic machinery conferring the enteroaggregative pattern of adhesion to the enterocyte described in enteroaggregative E. coli ( 10 , 11 ). (cdc.gov)
Other STEC strains harbor colonization factors of enterotoxigenic E. coli ( 12 , 13 ) and genes encoding virulence features associated with extraintestinal pathogenic E. coli (ExPEC) ( 14 , 15 ). (cdc.gov)
STEC O80 strains possess virulence genes carried by mobile genetic elements associated with intestinal and extraintestinal pathogenic E. coli ( 14 ). (cdc.gov)
Of the 196 sorbitol-negative E. coli strains, 3 (1.5%) carried the stx1 gene as did 2 of the 19 (10.5%) Citrobacter strains. (who.int)
We therefore investigated the prevalence of stx-encoding bacterial strains and typical virulence genes (stx1, stx2, eae and ehxA) in pathogenic bacteria isolated from diarrhoeal stool samples of patients taken during sporadic outbreaks of foodborne illness in the Islamic Republic of Iran. (who.int)
The scientists observed that the number of these repeats in Rpn S varies widely among different strains of the same bacterial species, suggesting a possible role in defense against phages, viruses that infect bacteria. (nih.gov)
Escherichia coli O104 is an emergent disease-causing bacterium various strains of which are becoming increasingly well known and troublesome. (sciencedaily.com)
July 23, 2019 A study of over 1,000 healthy women with no urinary tract infection symptoms showed nearly 9% carried multi-drug resistant Escherichia coli strains in their guts. (sciencedaily.com)
A combination of this enzyme with gold NPs has shown success in disrupting biofilms and killing bacterial strains such as Staphylococcus aureus , Staphylococcus epidermidis , E. coli , and P. aeruginosa through PTT/PDT. (eurekalert.org)
Colicins -- Any of various antibacterial substances produced by strains of intestinal bacteria, such as of E. coli , having a specific plasmid. (nih.gov)
It happens in all organisms from bacteria to humans, but the most detailed information is available from the study of mutant bacteria strains lacking the ability to make thymine, an essential building block for DNA. (i-sis.org.uk)
The study aimed to assess the efficacy of live E. coli expressing the N-glycan and glycosylated OMVs derived from them against different C. jejuni strains. (ed.ac.uk)
Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc. (lookformedical.com)
Active ingredients of ShigaShield are naturally occurring lytic bacteriophages that kill Shigella species, including strains belonging to the three major disease-causing species: S. flexneri, S. sonnei and S. dysenteriae. (foodnavigator.com)
Once they are released, these bacteria-killing proteins are particularly effective against bacterial strains that have altered parts of their surface in such a way that the phages no longer recognise them. (sciena.ch)
Most E. coli strains are harmless, but some, such as serotype O157:H7 , can cause serious food poisoning in humans, and are occasionally responsible for costly product recalls . (wikidoc.org)
[1] [2] The harmless strains are part of the normal flora of the gut , and can benefit their hosts by producing vitamin K 2 , or by preventing the establishment of pathogenic bacteria within the intestine . (wikidoc.org)
A strain of E. coli is a sub-group within the species that has unique characteristics distinguishing it from other E. coli strains . (wikidoc.org)
Different strains of E. coli are often host -specific, making it possible to determine the source of fecal contamination in environmental samples. (wikidoc.org)
Depending on which E. coli strains are present in a water sample, for example, assumptions can be made about whether the contamination originated from a human, other mammal, or bird source. (wikidoc.org)
New strains of E. coli evolve through the natural biological process of mutation , and some strains develop traits that can be harmful to a host animal. (wikidoc.org)
These molecules exhibit significant potency against other bacteria (including antibiotic-resistant strains), are stable and can have narrow or broad activity spectra. (nature.com)
This vision is gradually changing due to increasing evidence of the multiplicity of genotypes [ 2 ] (in its broadest sense, i.e. including strains and species) infecting the same species of plant, animal or bacterial host [ 3 , 4 , 5 , 6 ]. (biorxiv.org)

Just as surprising, two thirds of the samples that contained bacteriophages didn't contain their supposed host Escherichia coli , which suggests phages can be transported without bacteria, the researchers said in a press release . (medscape.com)
Further experiments revealed that the Rpn L -Rpn S toxin-antitoxin system helps protect the bacterium Escherichia coli against infection with certain phages. (nih.gov)
He and other scientists have shown that phages, as bacteriophages are often called, could help us fight bacteria that have developed resistance to antibiotics . (nih.gov)
He used phages as tools to move DNA between bacteria, but the viruses weren't his focus. (nih.gov)
But Dr. Young's observations suggested that phages could not only infect bacteria but also intentionally trigger lysis. (nih.gov)
He ultimately discovered two ways that phages cause bacteria to burst: multigene lysis and single-gene lysis. (nih.gov)
The application of lytic bacteriophages (phages) that show specificity towards malodour-producing species could therefore be selectively used to remove malodourous bacteria. (lpmhealthcare.com)
In a cosmetic context, phages offer a natural solution towards controlling the levels of target bacteria in the human axilla. (lpmhealthcare.com)
Gold and/or silver NPs can bind to bacteria and phages, facilitate the former's detection and the diagnosis of bacterial infection. (eurekalert.org)
Frequently encountered Bacillus phages include bacteriophage phi 29 and bacteriophage phi 105. (lookformedical.com)
All RNA phages infect their host bacteria via the host's surface pili. (lookformedical.com)
Virulent bacteriophage and type species of the genus T4-like phages, in the family MYOVIRIDAE. (lookformedical.com)
It infects E. coli and is the best known of the T-even phages. (lookformedical.com)
Virulent bacteriophage and type species of the genus T7-like phages, in the family PODOVIRIDAE, that infects E. coli. (lookformedical.com)
A series of 7 virulent phages which infect E. coli. (lookformedical.com)
ETH Zurich researchers have now developed a rapid test and a new therapeutic approach using bacteria-infecting viruses known as phages. (sciena.ch)
The researchers also genetically modified the phages to make them more efficient in destroying the pathogenic bacteria. (sciena.ch)
The first step was to identify the phages that are effective against the three main types of bacteria implicated in urinary tract infections, namely Escherichia coli, Klebsiella and Enterococci. (sciena.ch)
These natural phages were then modified in such a way that any bacteria they recognize and infect are propelled to produce an easy-to-measure light signal. (sciena.ch)
However, previous therapeutic approaches have one problem: "Phages aren't interested in completely killing their host, the pathogenic bacterium," explains ETH researcher Samuel Kilcher, one of the study's two final authors. (sciena.ch)
The modified phages produce not only new phages inside the infected host bacterium, but also bacteriocins. (sciena.ch)
Bacteriophages, or phages, are viruses that infect and kill bacteria. (phagovet.eu)
double-stranded dna phages of both gram-positive and gram-negative bacteria typically use a holin-endolysin system to achieve lysis of their host. (liverpool.ac.uk)

This therapeutic approach involves the use of bacteriophages that target and destroy pathogenic bacteria whilst being unable to infect humans. (inserm.fr)
The model confirms and extends the principle that bacteriophages act in synergy with the immune system of infected animals, enabling more effective elimination of pathogenic bacteria. (inserm.fr)
Using this method, the researchers were able to reliably detect the pathogenic bacteria directly from a urine sample in less than four hours. (sciena.ch)

MS2 bacteriophage is a positive sense, single-stranded RNA virus that infects the bacterium Escherichia coli. (pyure.com)
Phi-X174 bacteriophage is a circular single stranded DNA based virus that infects the bacterium Escherichia coli. (pyure.com)

A total of 532 stool and rectal swab samples from 70 sporadic outbreaks during May 2014 to August 2015 were examined for infection with Shiga toxin-producing bacteria. (who.int)
3], showing that a fraction of RNA is synthesized and degraded rapidly in E. coli infected with T2 bacteriophage, and a paper by Volkin and Astrachan [4], which showed that infection of E. coli by T2 bacteriophage resulted in the rapid turnover of a fraction of RNA that had the base composition of bacteriophage rather than the DNA of E. coli. (nih.gov)
In particular, the researchers used the bacteriophages' infection parameters determined in the laboratory (for example, the duration of the infectious cycle of the bacteria, the number of viruses released when a bacterium is destroyed…) and information collected during experiments using a mouse model of lung infection. (inserm.fr)
Analysis suggested transmission of multidrug-resistant EKE to newborns, emphasizing the need for infection prevention and antimicrobial stewardship programs to reduce the spread of drug-resistant bacteria in the hospital. (ed.ac.uk)
In the extra intestinal phase of infection by gram-negative bacteria, iron becomes one of the major factors that limit further growth. (medscape.com)
This model illustrates the role that CRISPR plays in defending bacteria from infection by focusing on a single cell surrounded by an unseen environment. (northwestern.edu)
With it, bacteria are able keep a heritable genetic record of past infection attempts, which makes them and their descendants much more effective at fending off future infections by the same or similar viruses. (northwestern.edu)
CRISPR is often very effective in protecting bacteria from infection. (northwestern.edu)

on the similar lines lytic bacteriophages has the potential to be exploited as an biocontrol for filamentous bacteria which may lead to foam reduction in the AS treatment plant [ 11 , 25 ]. (hindawi.com)

Escherichia coli (E coli O157:H7) that harbor this plasmid clinically behave as Shigella bacteria. (medscape.com)
To view specific information about E. coli O157:H7 strain, click here . (wikidoc.org)
It is believed that this process led to the spread of shiga toxin from Shigella to E. coli O157:H7. (wikidoc.org)

These tests identified 80 colonies of Escherichia coli per 100 g, 230 colonies of Vibrio parahaemolyticus per 100 g, and isolated colonies of V. vulnificus and V. fluvialis. (cdc.gov)

More than a quarter of the genome of this strain of E. coli comprises prophage elements, the team explains. (sciencedaily.com)
Some of the animals were infected with a bioluminescent strain of E. Coli (in order to best monitor it within the body). (inserm.fr)
Here, we report the identification of the D-galactan II-synthesizing genes by screening a transposon mutant library of an acapsulated Klebsiella pneumoniae O1 strain with bacteriophage. (frontiersin.org)
In the study, researchers found a gene in one strain of Escherichia coli (E. coli) that protects these bacteria against one of the antibiotics considered to be a last resort. (livescience.com)

Staphylococcus epidermidis, a Gram-positive bacterium and simulant for a range of medically significant pathogens such as Staphylococcus aureus ("staph" infections). (pyure.com)

This theory was supported by the absence of resolution when they co-transfected a mutated A22R and a cruciform-structure containing plasmid (which has a 'Holliday-like' junction) in cells infected with wild-type virus. (nih.gov)
However, the experiment was not designed to detect 'partial diploids' that carry a functioning thymine gene on a plasmid, which could then enable the bacterium carrying the interleukin gene disupting the thymine gene on its chromosome to escape cell death. (i-sis.org.uk)
a two-stage continuous culture of escherichia coli in combination with a bacteriophage lambda system was performed in order to overcome the intrinsic plasmid instability that is frequently observed in recombinant fermentation. (liverpool.ac.uk)
heterologous escherichia coli or bacteriophage lambda dna fragments of various sizes were inserted into vectors based on either the rolling-circle-type plasmid pwv01 or the theta-type plasmid pambeta1. (liverpool.ac.uk)

Studies on the lactic acid bacteria employed for beverage production. (microbiologyresearch.org)
Enterococci are Gram-positive lactic acid bacteria that naturally inhabit the human gut [ 3 ]. (springeropen.com)

Shiga toxin-producing Escherichia coli (STEC) O80:H2 has emerged in Europe as a cause of hemolytic uremic syndrome associated with bacteremia. (cdc.gov)
Shiga toxin-producing Escherichia coli (STEC) is a group of enteric pathogens that cause foodborne disease ranging from uncomplicated diarrhea to hemorrhagic colitis (HC) or hemolytic uremic syndrome (HUS) ( 1 ). (cdc.gov)
This study investigated the prevalence of Shiga toxin-producing bacteria in stool samples of patients with diarrhoea associated with outbreaks of foodborne illness in the Islamic Republic of Iran. (who.int)
Shiga toxin-producing bacteria are the main cause of bloody or non-bloody diarrhoea. (who.int)
While Shigella dysenteriae serotype 1 most commonly produces this toxin, other members of the Enterobacteriaceae family, such as Shiga toxin-producing Escherichia coli and enterohaemorrhagic E. coli, as well as Citrobacter spp. (who.int)
Cooperation of Shiga toxins with other virulence factors, such as aggregative adhesin and intimin (eae), could induce more severe disease in infected patients (3). (who.int)

E. coli, Shigella spp. (who.int)
Note that the exterior of the Shigella bacteria is fimbriated, covered by numerous thin, hair-like projections, imparting a furry appearance. (medscape.com)
DNA-DNA hybridization studies demonstrate that E.Coli share more than 75% nucleotide similarity with Shigella species and Shigella species appears to be metabolically inactive biogroups of E.coli. (medscape.com)

Feb. 23, 2023 People often associate Escherichia coli with contaminated food, but E. coli has long been a workhorse in biotechnology. (sciencedaily.com)

Transmission electron microscope image of T4Phage, a bacteriophage that infects Escherichia coli bacteria. (cellimagelibrary.org)
Transmission electron microscope image of T4Phage on the surface of Escherichia coli bacteria. (cellimagelibrary.org)
T4Phage is a bacteriophage that infects E. coli bacteria. (cellimagelibrary.org)

However, their species specificity is a double-edged sword, and may pose potential roadblocks to the clinical application of bacteriophages, coupled with their low bioavailability, and the risk of infectivity loss. (eurekalert.org)
There are only limited reports related to biological foam control methods especially the application of bacteriophages in AS systems [ 11 , 14 , 15 , 21 - 23 ]. (hindawi.com)

The isolates were examined for carriage of the virulence genes stx1 and stx2 in all isolates and eae/ehxA in Escherichia coli. (who.int)
In addition, small molecule approaches that interfere with pathogen virulence may provide effective therapy without exerting the same selective pressure as compounds that directly kill or inhibit bacteria. (nih.gov)
Genomic insights into virulence, antimicrobial resistance, and adaptation acumen of Escherichia coli isolated from an urban environment. (cdc.gov)
[13] As long as these bacteria do not acquire genetic elements encoding for virulence factors , they remain benign commensals . (wikidoc.org)

Detection of Salmonella Typhi bacteriophages in surface waters as a scalable approach to environmental surveillance. (cdc.gov)

Bacteriophages are of interest because they can transfer antibiotic resistance genes to the bacteria they infect, which becomes a problem for humans. (medscape.com)
The bacteriophage T4 infects the bacterium Escherichia coli , which normally inhabits the gastrointestinal tract of humans. (nih.gov)
Escherichia coli is a so-called gram negative bacterium, commonly found in the intestine of humans and other mammals. (sciencedaily.com)
Application of phylodynamics to identify spread of antimicrobial-resistant Escherichia coli between humans and canines in an urban environment. (cdc.gov)
Humans are the natural reservoir, although other primates may be infected. (medscape.com)
Some bacteria have finally breached the last wall of humans' antibiotic stronghold, according to a new study from China . (livescience.com)

This study describes the isolation and characterization of three Nocardia bacteriophages NOC1, NOC2, and NOC3 for the control of Nocardia species. (hindawi.com)

13 - 15 ] for the isolation of bacteriophages against filamentous bacteria responsible for the stable foam formation in ASP. (hindawi.com)
Isolation and some properties of a bacteriophage infected during the fermentation of lactic acid beverage. (microbiologyresearch.org)
Isolation of bacteriophages parasitic on Lactobacillus casei and L. plantarum and their several properties. (microbiologyresearch.org)
gene-specific random mutagenesis of escherichia coli in vivo: isolation of temperature-sensitive mutations in the acyl carrier protein of fatty acid synthesis. (liverpool.ac.uk)

The stx genes are encoded in the genome of heterogeneous lambdoid bacteriophages and can be passed to other bacteria during horizontal gene transfer (4). (who.int)
Escherichia coli , or E. coli -- Common bacterium that has been studied intensively by geneticists because of its small genome size, normal lack of pathogenicity, and ease of culture in the laboratory. (nih.gov)
The genome is the ring of darker blue near the center of the cell, representing the circular genome typical of bacteria. (northwestern.edu)

Cross-contamination of carbapenem-resistant Gram-negative bacteria between patients and the hospital environment in the first year of a newly built surgical ward. (cdc.gov)
S flexneri, enteroinvasive gram-negative bacteria, is responsible for the worldwide endemic form of bacillary dysentery. (medscape.com)
WbbY homologs, WbbZ homologs, and lipopolysaccharide structures based on D-galactan II also were present in several Gram-negative bacteria. (frontiersin.org)
is conserved among multiple species of Gram-negative bacteria and could be a useful vaccine candidate. (frontiersin.org)

In my opinion, the most exciting work in molecular biology in 1959 were the genetic experiments of Monod and Jacob on the regulation of the gene that encodes Corresponding author: Marshall Nirenberg ([email protected]). 8-galactosidase in Escherichia coli and that the mechan- ism of protein synthesis was one of the most exciting areas in biochemistry. (nih.gov)
Since that time, the key molecular components of homologous recombination have been dissected in Escherichia coli . (nih.gov)
DNA from bacteriophage lambda: molecular length and conformation. (microbiologyresearch.org)

At the Aerosol Research & Engineering Laboratories (ARE Labs), a U.S. laboratory specializing in the study of aerosolized microorganisms, Pyure conducted an evaluation of the kill rate on several pathogens, including viruses, bacteria and mold. (pyure.com)
Under this selection, resistant bacteria have a significant advantage for expansion and dissemination, leading to the evolution of multi-drug resistant pathogens for which there are extremely limited or no treatment options. (nih.gov)
While bacteriophages - viruses that kill bacteria - could be a solution for fighting antibiotic-resistant pathogens, various obstacles stand in the way of their clinical development. (inserm.fr)
And pathogens created from probiotic bacteria will be pre-adapted to invade and colonize the human gut. (i-sis.org.uk)
ETH Zurich researchers have developed a new rapid test that uses bacteriophages - viruses that infect bacteria - to quickly and accurately identify the pathogens that cause urinary tract infections. (sciena.ch)

Bacteriocins, which are antimicrobial peptides produced by certain bacteria, might warrant serious consideration as alternatives to traditional antibiotics. (nature.com)

But sitting on the shelf for decades is exactly what kept colistin viable in the battle against drug-resistant bacteria, Shaffner said. (livescience.com)
The new drug-resistant bacteria have not been found outside of China, the investigators said. (livescience.com)

Which one of the following organisms that infects the gastrointestinal tract is the MOST frequent cause of bacteremia? (labtestsguide.com)
E. coli normally colonizes an infant's gastrointestinal tract within 40 hours of birth, arriving with food or water or from the individuals handling the child. (wikidoc.org)

Many bacteria can secrete iron chelating compounds, or siderophores, which chelate iron from the intestinal fluids and which bacteria then take up to obtain iron for its metabolic needs. (medscape.com)
Bacteriocins can even be produced in situ in the gut by probiotic bacteria to combat intestinal infections. (nature.com)

Mutant thymine-minus bacteria have been prepared as gene therapy vectors for delivering human genes to patients. (i-sis.org.uk)
As human genes are not readily expressed in the bacterium because different DNA codons for the same amino acids tend to be used (codon bias), the disrupting gene inserted is a synthetic approximation of the human gene, with codons adjusted to suit the bacterium [8]. (i-sis.org.uk)

Jan. 10, 2019 The replication of a bacterial virus is not necessary to cause lethal disease in mice infected with a food-borne pathogen called Enterohemorrhagic Escherichia coli (EHEC), according to a new study. (sciencedaily.com)

Virulent bacteriophage and sole member of the genus Cystovirus that infects Pseudomonas species. (lookformedical.com)

Probiotic bacteria are beneficial bacteria living in the human gut that are now widely used as food additives for their health-promoting effects. (i-sis.org.uk)
Despite our warning, the first clinical trial using GM probiotic bacteria as gene therapy vector has taken place [2]. (i-sis.org.uk)
We took issue with their assertions [4] ( Reply to GM microbes for human health ), especially in their attempt to blur the distinction between GM and natural probiotic bacteria, which is misleading and dangerous. (i-sis.org.uk)

A species of gram-positive bacteria that is a common soil and water saprophyte. (lookformedical.com)

Bacteriophages , such as T4 are viruses that infect bacterial cells, can enter both the lytic and lysogenic cycles. (texasgateway.org)

the carboxy-terminal domain of the transcription factor escherichia coli nusa, nusactd, interacts with the protein n of bacteriophage lambda, lambdan, and the carboxyl terminus of the e. coli rna polymerase alpha subunit, alphactd. (liverpool.ac.uk)
two-stage continuous operation of recombinant escherichia coli using the bacteriophage lambda q- vector. (liverpool.ac.uk)
display of aggregation-prone ligand binding domain of human ppar gamma on surface of bacteriophage lambda. (liverpool.ac.uk)

The bacteria self-organized into a sand dollar-like pattern to form a cohesive structure called a biofilm. (nih.gov)
describes a flow-cell system with a chamber containing a submerged, preformed Escherichia coli biofilm. (asmblog.org)
We showed the ability of two isolated bacteriophages to efficiently destroy biofilm formed by S. haemolyticus and S. lugdunensis which is one of the main bacterial species associated with production of body malodour. (lpmhealthcare.com)
Biofilms are where bacteria join together on a surface and start to form a protective matrix around their group, examples include dental plaque, a slimy biofilm of bacteria forming on the surfaces of teeth. (health-innovations.org)

Solutions are urgently required for the growing number of infections caused by antibiotic-resistant bacteria and to address the fact that broad-spectrum antibiotics can considerably harm the commensal human microbiota. (nature.com)
Solutions are urgently required for the growing number of infections caused by antibiotic-resistant bacteria. (nature.com)
But the constant presence of antibiotics in the livestock diet helps drive the increasing numbers of antibiotic resistant bacteria today, researchers say. (livescience.com)

Filtering face piece respirators are usually tested utilizing nonbiologic particles, whereas their use often aims at reducing exposure to biologic aerosols, including infectious agents such as viruses and bacteria. (nih.gov)
Results show the amino coating prompts the bacteriophages to bond with the clusters head-first, leaving their infectious tails exposed and able to infect bacteria. (health-innovations.org)
In natural environments bacteria are challenged with infectious viruses very often, so bacteria must have ways to defend themselves in order to survive. (northwestern.edu)
Our ability to make new antibiotics will always be outpaced by the ability of bacteria to devise resistance mechanisms," said Dr. Amesh A. Adalja, an infectious disease specialist and senior associate at the University of Pittsburgh Medical Center's Center for Health Security. (livescience.com)

Researchers grew in a lab dish Bacillus licheniformis , a usually benign bacterium from the soil that produces an enzyme used in laundry detergent. (nih.gov)
Now, a study led by researchers Rice University develops magnetic bacteriophages, viruses known to infect bacteria, in nanoclusters with the power to punch through biofilms to reach bacteria fouling water treatment systems. (health-innovations.org)
Researchers at ETH Zurich, in collaboration with Balgrist University Hospital, have now developed a rapid test that employs the natural viral predators of bacteria, bacteriophages. (sciena.ch)
In the study, the researchers found the gene, called mcr-1, in samples of E. coli that were taken from pigs, pork products and infected people. (livescience.com)
In the new study, the researchers found the gene for colistin resistance in bacterial structures called plasmids, which are small circles of DNA that are easily passed from one bacterium to another, and even between different bacterial species. (livescience.com)
Researchers have long known that the use of antibiotics, in both agriculture and in medicine, has encouraged bacteria to do what they've excelled at for more than 3 billion years: evolve and survive. (livescience.com)

The scientists were digging into what they call "viral dark matter": the populations of bacteriophages - viruses that infect bacteria - that occupy the human body. (medscape.com)
The last stage of viral replication is the release of the new virions produced by the host that are able to infect other cells. (texasgateway.org)

Bacteria are single-celled organisms that are too small to see in detail without the aid of a microscope. (nih.gov)
Viruses are host-specific because they only can attach to and infect cells of certain organisms. (texasgateway.org)
[6] [7] The bacteria can also be grown easily and its genetics are comparatively simple and easily-manipulated, making it one of the best-studied prokaryotic model organisms , and an important species in biotechnology . (wikidoc.org)
Since many pathways in mixed-acid fermentation produce hydrogen gas, these pathways require the levels of hydrogen to be low, as is the case when E. coli lives together with hydrogen-consuming organisms such as methanogens or sulfate-reducing bacteria . (wikidoc.org)

infected bacteria then produce the protein ( 7 ). (cdc.gov)
All the vivid colors you see in the images help to distinguish between the various proteins or protein subunits that make up the intricate structure of the bacteriophage and its DNA packaging machine. (nih.gov)
The way I look at it is each protein is pointing to a self-destruct button somewhere in the bacteria," says Dr. Young. (nih.gov)
moreover, recent data indicate that the acyl carrier protein of escherichia coli has a large protein interaction network that extends beyond lipid synthesis. (liverpool.ac.uk)

A family of bacteriophages containing one genus (Cystovirus) with one member (BACTERIOPHAGE PHI 6). (lookformedical.com)

Antagonistic coevolution (AC) between bacteria and bacteriophages plays a key role in driving and maintaining microbial diversity. (nih.gov)

When bacteria become resistant to even the last-resort antibiotics and can share that resistance with other types of bacteria, that leaves the human population extremely vulnerable to a range of infections that would be unstoppable, he said. (livescience.com)

These elements the team explains are genetic weapons that protect the bacteria from antibiotics and have been acquired from viruses, known as bacteriophages, that usually infect bacteria. (sciencedaily.com)

For example, naturally predatory bacteriophage that target and kill a specific bacterial pathogen have demonstrated therapeutic capability. (nih.gov)
Bacteriophages are viruses naturally present in the environment that can kill specific host bacteria. (foodnavigator.com)

Bacteria -- Single-celled microorganisms without a nuclear membrane, distinct nucleus, or DNA organized in chromosomes. (nih.gov)
Since many antibiotics are derived from microorganisms, when doctors use these drugs against bacteria, "we're playing in their field," Adalja added, presenting them with an opponent that evolution has primed them to defeat. (livescience.com)

E. coli was discovered by a German pediatrician and bacteriologist Theodor Escherich in 1885, and is now classified as part of the Enterobacteriaceae family of gamma-proteobacteria . (wikidoc.org)

Non-traditional therapeutics have the potential to transform treatment of patients infected with resistant bacteria, reduce the spread of resistance and reinvigorate the dwindling pipeline of antibacterial agents. (nih.gov)
Each year, these resistant bacteria are estimated to be responsible for 700,000 deaths worldwide . (inserm.fr)

Our experiments confirm that a population of proliferating E. coli in a microchannel organizes into lanes of genetically identical cells within a few generations. (oist.jp)
This allows the human gene to be expressed in the genetically modified bacterium in place of the thymine gene, and the disrupted thymine gene does not revert easily. (i-sis.org.uk)

Bacteriophages target different capsule- or O- types of K. pneumoniae by recognizing surface molecules. (frontiersin.org)

Some infected cells, such as those infected by the common cold virus known as rhinovirus, die through lysis (bursting) or apoptosis (programmed cell death), releasing all progeny virions at once. (texasgateway.org)
An Escherichia coli bacterium before lysis (left) and after (right). (nih.gov)

The device was able to determine the viability of a low amount of living bacteria attached to the cantilever, and was used to monitor T7 interaction with E. coli over a wide range of virus concentrations up to 109 PFU ml-1. (biofisica.info)

The discovery of antibiotics had revolutionized the history of medicine in the 20th century, allowing us to effectively fight bacteria for the first time. (inserm.fr)

The overuse of antibiotics over extended periods of time has led to the emergence of multidrug-resistant (MDR) bacteria in recent years. (eurekalert.org)
Bacteriophage SA14 was isolated from sewage water using the multidrug-resistant isolate as a host. (springeropen.com)

Bacteriophages can provide an effective and sustainable solution for the control of bacterial populations at various stages of the food chain: from animal to food processing facilities. (phagovet.eu)

A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. (lookformedical.com)
Escherichia coli ( Template:PronEng ) ( E. coli ), is a bacterium that is commonly found in the lower intestine of warm-blooded animals. (wikidoc.org)

Although the production of Stx plays a central role in the pathogenesis of STEC-associated illness, the development of HC and HUS requires an efficient host colonization by the infecting STEC. (cdc.gov)
Viruses replicate within a living host cell, producing changes in the cell that often result in the death of the infected cell. (texasgateway.org)
These bacteria have co-evolved with their human host over millions of years. (i-sis.org.uk)
Their contributions to health and to the development of the host's immune system depend on an intricate web of bacteria-bacteria and bacteria-host relationships that if thrown out of balance will most likely result in disease. (i-sis.org.uk)
The bacteriophage MS-2 was quantified using its Escherichia coli host. (cdc.gov)
Viruses whose host is Escherichia coli. (lookformedical.com)
Its natural host is E. coli K12. (lookformedical.com)

The current study utilizes bacteriophages which are polyvalent, meaning they're able to attack more than one type of bacteria, to target lab-grown films containing Escherichia coli (E. coli) and P. aeruginosa, which is prone to antibiotic resistance. (health-innovations.org)
Results show the bacteriophage-nanoclusters effectively killed E. coli and P. aeruginosa in over 90 percent of the film. (health-innovations.org)

E. coli and related bacteria possess the ability to transfer DNA via bacterial conjugation , transduction or transformation , which allows genetic material to spread horizontally through an existing population. (wikidoc.org)

To view a list of E. coli organ-based infections, click here . (wikidoc.org)

Old tools, new applications: Use of environmental bacteriophages for typhoid surveillance and evaluating vaccine impact. (cdc.gov)

Using their model, the scientists show that the route of administration is an important parameter to consider when it comes to improving the animals' survival: the more rapidly it brings the bacteriophages into contact with the bacteria, the more it is effective. (inserm.fr)

Anatomy5

Organisms44

Diseases3

Chemicals and Drugs50

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes60

Disciplines and Occupations3

Technology, Industry, Agriculture1

Information Science4

Health Care5

Phage26

Strains24

Phages23

Pathogenic bacteria3

Virus that infects2

Infection8

Lytic bacteriophages1

O157:H73

Vibrio1

Strain4

Staphylococcus1

Plasmid4

Lactic acid bac2

Shiga6

Shigella3

20231

T4Phage3

Application of bacteriophages2

Virulence4

Salmonella1

Humans6

Characterization1

Isolation4

Genome3

Gram-negative4

Molecular3

Pathogens5

Antimicrobial1

Drug resistant2

Gastrointestinal tract2

Intestinal2

Genes2

20191

Pseudomonas1

Probiotic bacteria3

Species of gram-positive1

Bacterial cells1

Lambda3

Biofilm4

Antibiotic-resistan3

Infectious4

Researchers6

Viral2

Organisms4

Protein4

Genus1

Antagonistic1

Types of bacteria1

Viruses known1

Naturally2

Microorganisms2

Enterobacteriaceae1

Resistant bacteria2

Genetically2

Pneumoniae1

Lysis2

Cantilever1

Fight bacteria1

Multidrug-resistant2

Populations1

Commonly found in the lower2

Host7

Aeruginosa2

Genetic1

Infections1

Vaccine1

Scientists1