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Infectious pancreatic necrosis virusBirnaviridae InfectionsSalmonidaeBirnaviridaeFish DiseasesSalmonReoviridaeAquabirnavirusSalmo salarTroutPancreatic DiseasesAquacultureRhabdoviridaeFishesOncorhynchus mykissGonadsRNA VirusesPancreatitis, Acute NecrotizingCapsid ProteinsCyprinidaeRNA, Double-StrandedNecrosisRNA, ViralInfectious hematopoietic necrosis virusViral Structural ProteinsVirus ReplicationCapsidMolecular Sequence DataGenome, ViralViral ProteinsCell LineNeutralization TestsAntigens, ViralBase SequencePicornaviridaePancreatitisSequence Analysis, DNARhabdoviridae InfectionsDensovirinae
IPNVISAVVHSVHematopoietic necrosis virusAquabirnavirusHaemorrhagic septicaemiaRhabdovirusesCapsid proteinBursal disease virusHaematopoietic necrosisAquatic birnavirusProteinDiseaseDiseasesPathogensSalmonidAcquired Immune DVaccinePustular vulvovaginitisGenusEconomically importantAvianSalmonidsNervousAtlanticMortalitySecretionsVirulentSubsequentFishHepatitisHemorrhagic
IPNV13
  • Infectious pancreatic necrosis virus (IPNV) is a double-stranded RNA virus from the family Birnaviridae, in the genus Aquabirnavirus. (wikipedia.org)
  • IPNV or IPNV-like viruses have been isolated worldwide from at least 32 families of saltwater and freshwater salmonids and non-salmonids fish including salmon, flatfish, pike, eels and others. (wikipedia.org)
  • In addition to persistence in hosts, IPNV is also perpetual in the environment, surviving across a range of conditions and capable of infecting fish with as little as 101 TCID50/ml of the virus. (wikipedia.org)
  • Infectious pancreatic necrosis disease virus (IPNV) causes infectious pancreatic necrosis disease (IPN) in fish - most disease has been documented in young, farmed salmonid fish. (wikipedia.org)
  • Infectious pancreatic necrosis disease virus (IPNV) is a bi-segmented, double-stranded RNA virus belonging to the Aquabirnavirus subgroup of the Birnaviridae. (wikipedia.org)
  • However, infectious pancreatic necrosis virus (IPNV) was found in small quantities at a facility. (thefishsite.com)
  • The expression stability of five commonly used housekeeping genes [beta-actin (ACTB), elongation factor 1-alpha (EF1A), ubiquitin (UBQ), glyceraldehyd-3-phosphate dehydrogenase (GAPDH) and tubulin alpha (TUBA)] were monitored in salmonid cell lines CHSE-214 and RTS11 after infection with two of the most fastidious fish pathogens, the facultative bacterium Piscirickettsia salmonis and the aquabirnavirus IPNV (Infectious Pancreatic Necrosis Virus). (pucv.cl)
  • All tested samples were free of IPNV, VHSV and VNN viruses as was determined by the methods of cell culture and PCR. (fsu.ua)
  • Nervous necrosis virus (NNV) and infectious pancreatic necrosis virus (IPNV) are pathogens of economic importance to the aquaculture industry. (usmd.edu)
  • NNV causes viral encephalopathy and retinopathy in more than 30 species of marine warm-water and cold-water fish, whereas IPNV causes pancreatic necrosis disease in salmon and trout species. (usmd.edu)
  • The most common viral diseases in salmon farming are pancreas disease (PD), caused by salmonid alphavirus (SAV), heart and skeletal muscle inflammation (HSMI), caused by piscine orthoreovirus 1 (PRV1), cardiomyopathy syndrome (CMS), caused by piscine myocarditis virus (PMCV), infectious salmon anaemia (ISA), caused by ISA virus (ISAV) and infectious pancreatic necrosis (IPN), caused by IPN virus (IPNV). (hi.no)
  • A vaccine for injection for Atlantic salmon to reduce mortality caused by infections with IPNV (Infectious pancreatic necrosis), Aeromonas salmonicida subsp. (msd-animal-health.ie)
  • Vaccine for active immunisation of Atlantic salmon to reduce infection with SPDV (Pancreas disease), IPNV (Infectious pancreatic necrosis) and Aeromonas salmonicida subsp. (msd-animal-health.ie)
ISAV4
  • My work was primarily focussed on the economically important pathogen infectious salmon anaemia virus (ISAV). (gov.scot)
  • Infectious salmon anaemia virus (ISAV) mucosal infection in Atlantic salmon. (gov.scot)
  • Host tropism of infectious salmon anaemia virus (ISAV) in marine and freshwater fish species. (gov.scot)
  • The Institute of Marine Research has investigated the prevalence of infectious salmon anaemia virus (ISAV) and salmonid alphavirus (SAV, PD-virus) infections in migrating wild Atlantic salmon postsmolts captured in 2020 in three fjord systems located in three aquaculture production areas (PO3, 5, 12). (hi.no)
VHSV9
  • In the aquaculture environment, this technique has been successfully used to detect, among other pathogens, viral hemorrhagic septicemia virus (VHSV), infectious hematopoietic necrosis virus (IHNV), salmon alphavirus (SAV), Piscirickettsia salmonis , Renibacterium salmoninarum , infectious salmon anemia virus (ISAV), and infectious pancreatic necrosis virus (IPNV). (thefishsite.com)
  • Viral hemorrhagic septicemia virus (VHSV), a fish rhabdovirus belonging to the Novirhabdovirus genus, causes severe disease and mortality in many marine and freshwater fish species worldwide. (biomedcentral.com)
  • Most viruses in the European VHSV genotype Ia are highly virulent for rainbow trout ( Oncorhynchus mykiss ), whereas, VHSV genotype IVb viruses from the Great Lakes region in the United States, which caused high mortality in wild freshwater fish species, are avirulent for trout. (biomedcentral.com)
  • This study describes molecular characterization and construction of an infectious clone of the virulent VHSV-Ia strain DK-3592B from Denmark, and application of the clone in reverse genetics to investigate the role of selected VHSV protein(s) in host-specific virulence in rainbow trout (referred to as trout-virulence). (biomedcentral.com)
  • Senegalese sole is susceptible to marine VHSV isolates but is not affected by freshwater isolates, which may indicate differences regarding virus-host immune system interaction. (biomedcentral.com)
  • Viral Haemorrhagic Septicaemia Virus (VHSV) is the causal agent of the viral haemorrhagic septicaemia (VHS), an important disease affecting farmed salmonid species. (biomedcentral.com)
  • Susceptibility of goldsinny wrasse, Ctenolabrus rupestris L. (Labridae), to viral haemorrhagic septicaemia virus (VHSV) genotype III: experimental challenge and pathology. (gov.scot)
  • Current research in my laboratory has focused on two fish rhabdoviruses - infectious hematopoietic necrosis virus (IHNV) and viral hemorrhagic septicemia virus (VHSV), which are members of the genus Novirhabdovirus of the Rhabdoviridae family. (usmd.edu)
  • We established the reverse genetics systems for both IHNV and VHSV whereby infectious rhabdovirus can be recovered entirely from cDNA clones. (usmd.edu)
Hematopoietic necrosis virus1
  • This form certifies that the fish lots from which the shipments originated have been sampled and virus assays were completed consistent with requirements and that viruses causing Oncorhynchus masou virus , the viral hemorrhagic septicemia virus , infectious hematopoietic necrosis virus , and infectious pancreatic necrosis virus have not been detected. (fws.gov)
Aquabirnavirus1
  • To date, only two other Aquabirnavirus are listed by the International Committee on Taxonomy of Viruses (ICTV), the Tellina virus and the Yellowtail ascites virus. (wikipedia.org)
Haemorrhagic septicaemia1
  • First isolation of viral haemorrhagic septicaemia (VHS) virus from turbot ( Scophthalmus maximus ) cultured in the Trabzon coastal area of the Black Sea in Turkey. (fsu.ua)
Rhabdoviruses1
  • Rhabdoviruses of the genus Vesiculovirus are an emerging group of pathogenic viruses and include perch rhabdovirus, pike-fry rhabdovirus, tench rhabdovirus, lake trout rhabdovirus and spring viraemia of carp virus. (marine.ie)
Capsid protein2
  • The composition of the surface of virus particles involves a specific area of the capsid protein VP2 linked to host specificity, virulence and serotype. (wikipedia.org)
  • Expression of a foreign epitope on infectious pancreatic necrosis virus VP2 capsid protein subviral particle (SVP) and immunogenicity in rainbow trout. (fsu.ua)
Bursal disease virus2
  • Together, the structure of VP4 provides insights into the mechanism of a recently characterized clan of serine proteases that utilize a lysine general base and reveals the structure of potential targets for antiviral therapy, especially for other related and economically important viruses, such as infectious bursal disease virus in poultry and infectious pancreatic necrosis virus in aquaculture. (rcsb.org)
  • Infectious bursal disease virus: IBD-VAC and CEVAC-IBVK. (expasy.org)
Haematopoietic necrosis3
Aquatic birnavirus2
  • An aquatic birnavirus, Infectious Pancreatic Necrosis Virus, is also an important agent of mortality. (int-res.com)
  • The blotched snakehead virus (BSNV), an aquatic birnavirus, encodes a polyprotein (NH2-pVP2-X-VP4-VP3-COOH) that is processed through the proteolytic activity of its own protease (VP4) to liberate itself and the viral proteins pVP2, X and VP3. (rcsb.org)
Protein3
  • Purified virus preparations complied with the WHO restrictions for the residual DNA and host cell protein contents. (zebov-detection.com)
  • Dual mutation events in the haemagglutinin-esterase and F protein from an Infectious salmon anaemia virus HPR0 genotype promote viral fusion and activation by an ubiquitous host protease. (gov.scot)
  • Effect of the Viral Hemorrhagic Septicemia Virus Nonvirion Protein on Translation via PERK-eIF2α Pathway. (usmd.edu)
Disease13
  • Causing the highly infectious disease Infectious pancreatic necrosis, the virus primarily affects young salmonids resulting in high mortality, occasionally surpassing 90 percent in the early stages. (wikipedia.org)
  • The virus is found in blood and may be associated with the disease. (thefishsite.com)
  • It is not clear whether virus Y causes the disease characterized by cardiac inflammation and anemia, which until now has been found in the four hatcheries. (thefishsite.com)
  • This disease is a highly contagious systemic disease, caused by a double stranded RNA virus of the family Birnaviridae. (marine.ie)
  • This disease is caused by a single stranded RNA virus of the family Togaviridae, genus Alphavirus known as the salmonid alphavirus. (marine.ie)
  • Intranasal vaccination of hamsters with a Newcastle disease virus vector expressing the S1 subunit protects animals against SARS-CoV-2 disease. (usmd.edu)
  • Ebola disease can be confused with other more common infectious diseases such as malaria, typhoid fever, meningococcemia, and other bacterial infections. (cdc.gov)
  • Due to these nonspecific symptoms, particularly early in the course of the disease, Ebola disease can be confused with other more common infectious diseases such as malaria . (cdc.gov)
  • There are two variants of the virus, one that causes disease (virulent, HPR-del) and one that does not cause disease (avirulent, HPR-0). (hi.no)
  • Diseases that might exist despite normal liver enzyme levels include metastatic liver disease (cancer) or cirrhosis without any current cell necrosis (a type of cell death). (drkaslow.com)
  • 10. Infectious bursal disease (Gumboro disease). (advocatekhoj.com)
  • Genemedi developed the antigen and antibody to detect the non-infectious disease such as immune dysfunction, abortion and teratology, nonbacterial diarrheic disease, Prion associated diseases (Scrapie, Bovine Spongiform Encephalopathy, Chronical Waste Disease), winter dysentery and so on. (genemedi.com)
  • Varicella (i.e., chickenpox) is a highly contagious disease caused by varicella zoster virus (VZV). (cdc.gov)
Diseases3
  • Infectious diseases are caused by pathogens. (cermaq.com)
  • In this scheme, accurate pathogen detection, ideally in the early stages of infection, is necessary in order to design adequate strategies to control key infectious diseases that seriously threaten the sustainability of aquaculture. (thefishsite.com)
  • iii) Name two viral diseases and their causal viruses. (rbsesolutions.com)
Pathogens1
  • Using the reverse genetics approach, we are investigating the function of viral proteins in virulence, host adaptation, pathogenesis, and creating attenuated viruses with vaccine potential against other fish pathogens. (usmd.edu)
Salmonid2
  • Infectious pancreatic necrosis in salmonid fish, causes significant losses to the aquaculture industry. (expasy.org)
  • Havforskningsinstituttet har undersøkt utbredelsen av infeksiøs lakseanemi virus (ILAV) og salmonid alfavirus (SAV, PD-virus) infeksjoner i utvandrende vill atlantisk postsmolt fanget i 2020 i tre fjordsystemer lokalisert i tre akvakultur produksjonsområder (PO3, 5, 12). (hi.no)
Acquired Immune D1
  • Acquired Immune Deficiency Syndrome (AIDS) in people is a results of the destruction of the immune system attributable to Human Immunodeficiency Virus (HIV) an infection . (zebov-detection.com)
Vaccine4
  • In mild of the not too long ago accepted Ebola virus illness vaccine based mostly on a recombinant vesicular stomatitis virus (rVSV-ZEBOV), we current the outcomes of our work on three novel VSV-vectored HIV vaccine candidates. (zebov-detection.com)
  • One dose (5 ml) of the vaccine contains at least 10 5.5 TCID50 inactivated BRS virus (strain EV 908) and at least 10 7.3 TCID50 Parainfluenza 3 virus (strain SF-4 Reisinger), together with 9 x 109 cells inactivated Mannheimia haemolytica bacteria (serotype A1) propagated under conditions of iron restriction. (msd-animal-health.ie)
  • A live intranasal vaccine against RSV and PI3 viruses for use in calves from the day of birth. (msd-animal-health.ie)
  • These recommendations represent the first statement by the Advisory Committee on Immunization Practices (ACIP) on the use of live, attenuated varicella virus vaccine -- VARIVAX -- manufactured by Merck and Company, Inc. and licensed in March 1995 for use in healthy persons greater than or equal to 12 months of age. (cdc.gov)
Pustular vulvovaginitis1
  • 10. Infectious bovine rhinotracheitis/infectious pustular vulvovaginitis. (advocatekhoj.com)
Genus2
Economically important1
  • My laboratory is studying the molecular biology of economically important fish viruses and focuses on viral pathogenesis and development of novel vaccines. (usmd.edu)
Avian3
  • Genetic subtyping and phylogenetic analysis of HA and NA from avian influenza virus in wild birds from Peru reveals unique features among circulating strains in America. (usmd.edu)
  • 2. Avian infectious bronchitis. (advocatekhoj.com)
  • 3. Avian infectious laryngotracheitis. (advocatekhoj.com)
Salmonids1
  • The natural hosts are salmonids and the type species is INFECTIOUS PANCREATIC NECROSIS VIRUS. (musc.edu)
Nervous1
  • Oral immunization with cell-free self-assembly virus-like particles against orange-spotted grouper nervous necrosis virus in grouper larvae, Epinephelus coioides . (fsu.ua)
Atlantic2
  • A Systematic Approach towards Optimizing a Cohabitation Challenge Model for Infectious Pancreatic Necrosis Virus in Atlantic Salmon (Salmo salar L. (plos.org)
  • This virus has caused two financially damaging outbreaks in Atlantic salmon aquaculture in Scotland (1998 and 2008), and a non-virulent strain has also been found in circulation. (gov.scot)
Mortality2
  • Due to its wide host range and high mortality, the virus is of great concern to global aquaculture. (wikipedia.org)
  • Four chimeric rVHSVdk viruses with the substitutions of the G, NV, G and NV, or G, NV and L genes from the avirulent pVHSVmi constructs were still highly virulent (100% mortality), while the reciprocal four chimeric rVHSVmi viruses with genes from pVHSVdk remained avirulent (0-10% mortality). (biomedcentral.com)
Secretions1
  • Chemical or reactive gastritis is caused by injury to the gastric mucosa resulting from reflux of bile and pancreatic secretions into the stomach, but it can also be caused by exogenous substances, including NSAIDs, acetylsalicylic acid, chemotherapeutic agents, and alcohol. (medscape.com)
Virulent1
  • First field evidence of the evolution from a non-virulent HPR0 to a virulent HPR-deleted infectious salmon anaemia virus. (gov.scot)
Subsequent1
  • Hepatocellular necrosis occurs and is associated with dysregulation of clotting factors and subsequent coagulopathy. (cdc.gov)
Fish4
  • Sequences from a virus (virus Y) have been found in material from diseased fish. (thefishsite.com)
  • In the case of targeting viral RNA, specifically for the diagnosis of the ISA virus in infected tissues of fish, the use of the elongation factor 1 alpha (ELF1α) has been demonstrated to be a reliable reference RNA-expressed control because of its stability and constant expression in Salmo salar organs, in both the presence and the absence of the ISA virus. (thefishsite.com)
  • To this end, we have expressed the major host-protective genes of these viruses in suitable expression systems and seek to develop virus-like particles (VLPs) based vaccines that could be fed orally to fish. (usmd.edu)
  • ADS is ideally positioned to serve aquaculture enterprises both locally and worldwide and in conjunction with other service units of the college, currently offers a wide range of fin-fish and shellfish (both bivalve and crustacean ) diagnostic and analytical testing in the disciplines of gross and microscopic pathology, bacteriology, virology (virus isolation), molecular testing, parasitology, toxicology and drug residue analysis, endocrinology and clinical pathology. (upei.ca)
Hepatitis3
  • Commonly, an abnormal blood test is the first indication that you have a virus that is causing the hepatitis. (drkaslow.com)
  • 6. Duck virus hepatitis. (advocatekhoj.com)
  • Worldwide prevalence of hepatitis B virus and hepatitis C virus among patients with cirrhosis at country, region, and global levels: a systematic review. (who.int)
Hemorrhagic1
  • Genotyping and Pathogenicity of Viral Hemorrhagic Septicemia Virus from Free-Living Turbot ( Psetta maxima ) in a Turkish Coastal Area of the Black Sea. (fsu.ua)