• Her PhD studies focused on development of new anti-infective agents against tuberculosis and parasitic infections. (monash.edu)
  • Her research interests focus on S. aureus and the development of new anti-infective agents. (tuftsmedicalcenter.org)
  • Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. (benthamscience.com)
  • Tuberculosis (TB) is an ancient life-threatening infectious disease currently rated among the top ten causes of death worldwide. (frontiersin.org)
  • Besides, major infectious diseases like tuberculosis, kala-azar, malaria, elephantiasis, polio, leprosy, etc (from tropical countries), which could be controlled in the last century by large-scale eradication program or chemotherapy are re-emerging, causing outbreaks due to the virulence of existing organisms or accumulation of susceptible host. (benthambooks.com)
  • Provides updated and expanded coverage of emerging infectious diseases such as multidrug resistant tuberculosis (MDR-TB), neuroangiostrongyliasis (rat lungworm disease), Ebola virus, Severe Acute Respiratory Disease (SARS), Middle East Respiratory Syndrome (MERS), Coronavirus Infectious Disease-2019 (COVID-19), and novel influenza viruses including public health concerns. (libreriacortinamilano.it)
  • Six infectious diseases -- pneumonia, tuberculosis, diarrheal diseases, malaria, measles and HIV/AIDS -- account for half of all premature deaths worldwide. (malaria.com)
  • In disease prevention and control, sustained efforts are required against endemic diseases such as malaria, tuberculosis, poliomyelitis, rabies and HIV/AIDS, and against those diseases that periodically emerge as epidemics, including cholera, meningitis and influenza. (who.int)
  • Having routine surgery such as caesarean sections or hip replacements may become life threatening, and complications from common diseases such as diabetes and injuries or cuts will become harder to manage because of growing resistance to antibiotics in patients. (newswire.co.kr)
  • For example, the projects may include diagnostic tools for infectious diseases, and antibiotics and other anti-infective agents, among others. (who.int)
  • Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. (benthamscience.com)
  • The Centers for Disease Control and Prevention (CDC) recommends that clinicians reserve linezolid for more severe infections after consultation with an infectious disease specialist or for those patients who have not responded to other antibiotics. (conduent.com)
  • The last century has achieved remarkable breakthroughs in controlling various infectious diseases by synthesizing and modifying antibiotics. (benthambooks.com)
  • Anti-infective drugs include: anti-viral therapeutics, antibiotics, anti-fungal agents and prophylactic treatments such as vaccines. (malaria.com)
  • Chee Wei has a strong interest in finding new therapeutics to address the unmet medical needs in infectious diseases. (monash.edu)
  • also to provide general information about infectious diseases, anti-infective agents, and vaccines. (cdc.gov)
  • More specifically, numerous studies suggest that the composition of the microbiome has a genuine influence on the response to immunotherapy drugs for treating cancer or infectious diseases, as well as to antivirals and vaccines. (pharmiweb.com)
  • Having maintained a life-long interest in infectious diseases, he has focused on researching and developing innovative human monoclonal antibodies and vaccines designed to address life-threatening infections. (antimicrobialsworkinggroup.org)
  • The Infectious Diseases Society of America (IDSA) is a community of over 11,000 physicians, scientists and public health experts who specialize in infectious diseases. (ubc.ca)
  • The 2005 guideline from the Infectious Diseases Society of America recommended that ASB should be screened for and treated only in pregnant women or in an individual prior to undergoing invasive urologic procedures. (ubc.ca)
  • The Infectious Diseases Society of America (IDSA) guidelines on management of febrile neutropenia. (ubc.ca)
  • 10 x '20 Progress: Development of New Drugs Active against Gram-negative Bacilli - An Update from the Infectious Diseases Society of America. (tuftsmedicalcenter.org)
  • Chapters of this volume focus on the pathogenesis and etiology of each of the mentioned diseases, updated WHO reports wherever applicable, conventional drugs and their pharmacokinetics as well as new approaches to develop anti-infective agents. (benthambooks.com)
  • Anti-infective agents have been a crucial tool in the management of infectious diseases caused by bacteria, viruses, fungi, and parasites. (hilarispublisher.com)
  • There is no better resource for learning to associate pathogens with the corresponding impact on patients than Infectious Diseases. (libreriacortinamilano.it)
  • Antimalarials such as quinone, artemesinin, etc . have been extracted from medicinal plants and these anti-infective agents have shown promising results clinically against malaria. (benthambooks.com)
  • Covers vector-borne diseases including malaria, yellow fever, Zika infections and congenital Zika syndrome, West Nile fever, Lyme disease, tick-borne encephalitis, and Chagas disease plus others. (libreriacortinamilano.it)
  • Before the parasite that caused malaria was discovered, people thought the disease was caused by foul air, and associated it with marshes and low-lying swamps. (malaria.com)
  • Produced by the National Institute of Allergy and Infectious Diseases (NIAID), this illustration depicts the Life Cycle of the Malaria Parasite , differentiating between the parasites' development inside the mosquito vector, and development while inside the human host, specifically, inside the liver hepatocytes, and red blood cells (RBCs) circulating in the blood. (cdc.gov)
  • Anti Infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. (benthamscience.com)
  • Clinical Infectious Diseases 2014. (tuftsmedicalcenter.org)
  • Drs. Elaine Jong and Dennis Stevens cover the wide spectrum of illness and disease in this complex field using memorable illustrations by world-renowned artist Frank H. Netter and others, offering a time-saving, authoritative look at infectious disease risk factors, clinical presentations, pathophysiology, and more. (libreriacortinamilano.it)
  • A proven way to learn the principles of clinical infectious diseases in just thirty days Infectious Diseases: A Clinical Short Course, Fourth Edition is a concise overview of this important field designed to help the busy physician, medical student, nurse practitioner, and physician assistant to understand, diagnose, and treat common infectious diseases. (libreriacortinamilano.it)
  • A wide array of tables that summarize the methods of clinical assessment, anti-infective agent doses, and drug toxicities--facts that do not require memorization, but do need to be referred to when caring for patients--facilitate this condensed learning schedule. (libreriacortinamilano.it)
  • The largest clinical review of immune responses to paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs), and opioid analgesics, with a focus on infectious diseases, has provided insights into unintended impacts of these commonly used medicines. (scitechdaily.com)
  • Pain researcher Dr. Christina Abdel-Shaheed, from Sydney Musculoskeletal Health, said the relationships uncovered with infectious diseases highlighted the need for rigorous clinical trials. (scitechdaily.com)
  • Since 1969, The Sanford Guide to Antimicrobial Therapy has been the leading clinical reference for treatment of infectious diseases. (spmi.pt)
  • SAN DIEGO--( BUSINESS WIRE )--Cidara Therapeutics, Inc. (Nasdaq:CDTX), a biotechnology company developing novel anti-infectives and immunotherapies to treat fungal and other infections, today announced that the first patient has been dosed in RADIANT, a Phase 2 clinical trial comparing the safety and tolerability of the novel echinocandin, CD101, to standard-of-care fluconazole for the treatment of acute vulvovaginal candidiasis (VVC). (biospace.com)
  • Cidara is a clinical-stage biotechnology company focused on the discovery, development and commercialization of novel anti-infectives for the treatment of diseases that are inadequately addressed by current standard-of-care therapies. (biospace.com)
  • He led the Anti-Infectives Research Group at Pfizer's Sandwich R&D site and played a key role in progressing novel compounds through clinical trials, including maraviroc (Selzentry) a first-in-class HIV entry inhibitor. (bsac.org.uk)
  • René Russo, PharmD, BCPS, has spent more than 15 years in anti-infective R&D and has leadership experience across all phases of drug development, including global commercial launches for five novel antibacterial agents and clinical development and registration of several antiviral, antibacterial, and antifungal therapeutics. (antimicrobialsworkinggroup.org)
  • Each topic focuses on preclinical, translational and clinical aspects and will be a valuable experience for all involved in infectious diseases, as researchers or prescribers of anti-infective agents. (fcarvturin.it)
  • New actinomycetes are now being searched from unexplored or underexplored ecosystems for the development of new antimicrobials against disease organisms. (benthambooks.com)
  • Antimicrobials have become indispensable tools for decreasing morbidity and mortality associated with a host of infectious diseases and, since the introduction of antimicrobials into veterinary medicine, animal health and productivity have improved significantly. (climatechangelegalblogarchive.com)
  • We are pleased to announce that Jie Sun, PhD, will join the Division of Infectious Diseases and International Health as a Professor in January 2022. (virginia.edu)
  • Garlic was used in World War I as an anti-infective agent for various infectious intestinal diseases, including cases of cholera and dysentery. (jontristermd.com)
  • Various infectious complications can be successfully prevented with appropriate risk management strategies. (bvsalud.org)
  • Anti-infective agents are secondary metabolites produced and obtained from a different sources (plants, bacteria, virus, fungi, and marine oceans) with antibacterial or antiviral properties. (benthamscience.com)
  • Anti-infective agents (antibacterial or antiviral) possess either a bactericidal/virucidal or bacteriostatic /virustatic ability against microbes and viruses. (benthamscience.com)
  • ABSTRACT This study compared the utilization and cost of antibacterial agents in surgical units of 2 government hospitals in Palestine. (who.int)
  • The total consumption of antibacterial agents was 414.1 DDD and 591.5 DDD at Thabet and Rafidia hospitals respectively. (who.int)
  • Moreover, it has confirmed antibacterial effects on Gram-negative and Gram-positive bacteria and is commonly used as an antibacterial agent in dental hygiene products such as toothpastes and mouthwashes 8 . (bvsalud.org)
  • Venatorx is developing new antibacterial therapeutic products to address multi-drug resistant gram negative bacteria, including resistant E. coli , K. pneumoniae , and P. aeruginosa , important causative agents for complicated urinary tract infections, complicated intra-abdominal infections and many types of serious pneumonia. (antimicrobialsworkinggroup.org)
  • Universal pharmacological anti-herpes, antibacterial or antifungal prophylaxis is not warranted. (bvsalud.org)
  • Manual of antimicrobial therapy and infectious diseases / Mickey S. Eisenberg, Clifton Furukawa, C. George Ray. (who.int)
  • Gloria G. Guerrero Manriquez , " Frontiers in Anti-infective Agents ", Bentham Science Publishers (2020). (benthamscience.com)
  • Ricardo Ney Cobucci , " Frontiers in Anti-infective Agents ", Bentham Science Publishers (2020). (eurekaselect.com)
  • CD101 topical is the first topical agent in the echinocandin class of antifungals and exhibits a broad spectrum of fungicidal activity against Candida species. (biospace.com)
  • Antibody-based therapies for emerging infectious diseases. (cdc.gov)
  • In 2009, the American Association of Blood Banks (AABB) published a detailed description of 68 infectious agents capable of being transmitted by blood transfusion and prioritizing emerging infectious diseases for which there was not yet an implemented intervention. (medscape.com)
  • Overall, our data anticipate a biological role for human antimicrobial RNases in host response to mycobacterial infections and set the basis for the design of novel anti-tubercular drugs. (frontiersin.org)
  • Increased mortality rates, nosocomial infections, and reduced drug availability against such resistance organisms have generated an urgency for new antimicrobial agents. (benthambooks.com)
  • For diseases like AIDS where successful chemotherapy is still not possible, new challenges exist in controlling opportunistic infections such as skin and mouth infections, nervous subsystem disorders, respiratory disorders, as well as cancers. (benthambooks.com)
  • Isavuconazole, an azole antifungal agent, is currently undergoing international phase III trials with centers in the US, Europe and other regions in patients with invasive fungal infections caused by Aspergillus or other filamentous fungi (mold infections) and Candida fungi (yeast infections). (astellas.com)
  • Because of the relatively common occurrence of some infections during pregnancy, there is a great importance of studying them, therefore, knowing the classification of the drugs and identifying which agents are safe during pregnancy will both be discussed in this chapter. (eurekaselect.com)
  • The Centers for Disease Control and Prevention (CDC) guidelines recommend using only topical antifungal products to treat pregnant women with vulvovaginal yeast infections. (biospace.com)
  • From the 1st of February 2018 patients underwent a microbiological screening and were evaluated by an infectious disease specialist (IDs) before monoclonal antibodies infusion to rule out active infections. (bvsalud.org)
  • After repeat testing, if species identification and vancomycin test results are consistent, immediately contact the state health department (SHD) and CDC's Hospital Infections Program, National Center for Infectious Diseases, telephone (404) 639-6400, to report the occurrence of a 'presumptive' staphylococcal strain with reduced susceptibility to vancomycin and to obtain epidemiologic and laboratory assistance. (cdc.gov)
  • The neuraminidase inhibitors oseltamivir and zanamivir are the primary antiviral agents recommended for the treatment of influenza infections, 4,5 yet antiviral resistance to influenza A viruses is increasingly being reported. (who.int)
  • Mike currently heads Centauri Therapeutics Limited, a privately-owned UK Biotech with a novel immunotherapeutic platform ("Alphamers") for infectious diseases. (bsac.org.uk)
  • Mike is also a Director of Avvinity Therapeutics that is developing Alphamers as immunooncology agents. (bsac.org.uk)
  • As of April 24, this year has exceeded the greatest number of measles cases in the United States since the disease was declared eliminated here in 2000. (ubc.ca)
  • At the same time, rapidly developing resistance of microbes to anti- infective drugs is undermining treatment of bacterial, viral and parasitic diseases, weakening the weapons against them. (who.int)
  • CLL is associated with an increased risk of infectious complications. (bvsalud.org)
  • In this paper we reviewed the international guidelines on prevention and management of infectious complications in patients with CLL treated with BTK or BCL-2 inhibitors. (bvsalud.org)
  • BACKGROUND: Monoclonal antibodies have been a milestone in the treatment of multiple sclerosis (MS). Infective complications have been observed in patients on agents targeting lymphoid cells' surface antigens, namely anti-CD52 (alemtuzumab) and anti-CD20 agents (ocrelizumab and rituximab). (bvsalud.org)
  • Crohn's disease can be both painful and debilitating, and sometimes may lead to life-threatening complications. (rxwiki.com)
  • Dental caries is a common infectious disease, in which enamel and dentin are demineralized due to the acids produced from the fermentation of carbohydrates by acidogenic bacteria 1 . (bvsalud.org)
  • The system includes descriptions and findings for potential bioterrorism agents, and is updated weekly to account for potential outbreaks. (cdc.gov)
  • Every week, newspapers across the country describe large and small outbreaks of viral and bacterial diseases. (drugdiscoverynews.com)
  • microbiota composition plays a factor in the onset of numerous conditions including inflammatory diseases, such as Crohn's disease, infectious diseases, metabolic diseases, such as type 2 diabetes, auto-immune and central nervous system diseases. (pharmiweb.com)
  • Within the RNaseA superfamily there is a group of highly cationic proteins secreted by innate immune cells with anti-infective and immune-regulatory properties. (frontiersin.org)
  • Our review shows some of the common pain and fever medications may work with the immune system to fight infection, whereas others work against it and increase the risk of contracting or responding badly to infectious diseases," Dr. Abdel-Shaheed said. (scitechdaily.com)
  • Bowel flora play an important role in our ability to fight infectious disease, providing a front line in our immune defense, provide a passive mechanism to prevent infection, and produce many vitamins. (jontristermd.com)
  • The anti-TB drugs commonly used are insufficient and have multiple adverse effects. (benthamscience.com)
  • Devise a plan to manage drug interactions and adverse effects anti-infective treatments and optimize treatment responses. (fcarvturin.it)
  • METHODS: We led a retrospective/prospective real-life study to evaluate the effectiveness of a program of screening and prophylaxis for infective adverse events in patients with multiple sclerosis and related disorders treated with drugs directed against CD20/52 antigens. (bvsalud.org)
  • The burden of communicable diseases has been a key impediment to social and economic progress, imposing considerable suffering on people already living in adverse conditions. (who.int)
  • WHO model prescribing information : drugs used in sexually transmitted diseases and HIV infection. (who.int)
  • Drugs used in sexually-transmitted diseases and HIV infection. (who.int)
  • 8. Boucher H.W. Challenges in Anti-Infective Development in the Era of Bad Bugs, No Drugs: A Regulatory Perspective Using the Example of Bloodstream Infection as an Indication. (tuftsmedicalcenter.org)
  • In addition, many of the agents have activity against methicillin-resistant Staphylococcus aureus (MRSA) infection. (conduent.com)
  • The COVID-19 pandemic has placed infection research into the spotlight, highlighting once again the complexity and devastating impact that infectious diseases can have. (fcarvturin.it)
  • Efficacy of early treatment with anti-SARS-CoV-2 spike protein monoclonal antibodies (mAbs) for nosocomial SARS-CoV-2 infection in hematologic patients is unknown. (bvsalud.org)
  • Changes in susceptibility to infectious diseases, increased opportunities for infection, and the rapid adaptation of microbial agents are among the factors contributing to this evolution. (who.int)
  • Up to 3 organisms per HAI motion at the Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • This program has been adapted from the protocol developed by herbalist Hein Zeylstra for the management of Crohn's disease and ulcerative colitis. (jontristermd.com)
  • Crohn's disease causes inflammation and irritation in the digestive tract. (rxwiki.com)
  • Crohn's disease is manageable with medicines and/or surgery. (rxwiki.com)
  • Crohn's disease is a disease that causes inflammation (swelling) and irritation of the digestive or gastrointestinal tract. (rxwiki.com)
  • Crohn's disease can affect any part of the digestive tract from the mouth to the anus, but the most commonly affected section is the lower part of the small intestine called the ileum. (rxwiki.com)
  • Crohn's disease is 1 of 2 main forms of diseases that are called inflammatory bowel disease (IBD). (rxwiki.com)
  • The inflammation caused by Crohn's disease often spreads deep into the layers of affected bowel tissue. (rxwiki.com)
  • Both men and women can get Crohn's disease, and it can run in families. (rxwiki.com)
  • People with Crohn's disease may have a blood relative with the disease or another type of IBD. (rxwiki.com)
  • Crohn's disease most commonly starts between the ages of 13 and 30. (rxwiki.com)
  • There is no known cure for Crohn's disease, but therapies can greatly reduce its signs and symptoms and even bring about long-term remission. (rxwiki.com)
  • With treatment, many people with Crohn's disease are able to function well. (rxwiki.com)
  • Signs and symptoms of Crohn's disease can range from mild to severe. (rxwiki.com)
  • Crohn's disease symptoms can be different for each person. (rxwiki.com)
  • People with severe Crohn's disease may also experience inflammation of skin, eyes and joints or inflammation of the liver or bile ducts. (rxwiki.com)
  • Children with Crohn's disease may experience delayed growth or sexual development. (rxwiki.com)
  • The exact cause of Crohn's disease remains unknown. (rxwiki.com)
  • Previously, diet and stress were suspected, but now doctors know that these factors may aggravate but do not cause Crohn's disease. (rxwiki.com)
  • It is possible that a virus or bacterium may trigger Crohn's disease. (rxwiki.com)
  • Crohn's disease is more common in people who have family members with the disease, so genes may play a role in making people more susceptible. (rxwiki.com)
  • However, most people with Crohn's disease do not have a family history of the disease. (rxwiki.com)
  • Crohn's disease can occur at any age, but you are likely to develop the condition when you are young. (rxwiki.com)
  • Most people who develop Crohn's disease are diagnosed before 30 years old. (rxwiki.com)
  • Although Crohn's disease can affect any ethnic group, Caucasians and people of Eastern European (Ashkenazi) Jewish descent have the highest risk. (rxwiki.com)
  • People who have a close relative, such as a parent, sibling .or child, with the disease are more likely to develop Crohn's. (rxwiki.com)
  • Cigarette smoking is the most important controllable risk factor for developing Crohn's disease. (rxwiki.com)
  • NSAIDs do not cause Crohn's disease, but they can lead to inflammation of the digestive tract that makes Crohn's disease worse. (rxwiki.com)
  • People who live in an urban area or in an industrialized country are more likely to develop Crohn's disease. (rxwiki.com)
  • This suggests that environmental factors, including a diet high in fat or refined foods, play a role in Crohn's disease. (rxwiki.com)
  • Your doctor will likely diagnose Crohn's disease only after ruling out other possible causes for your signs and symptoms. (rxwiki.com)
  • There is no single test to diagnose Crohn's disease. (rxwiki.com)
  • Your doctor will likely perform a physical exam and use a combination of endoscopy with biopsies and radiological testing to confirm a diagnosis of Crohn's disease. (rxwiki.com)
  • The implementation of new anti-TB drugs together with host-directed therapy (HDT) can decrease the duration of treatment and improve the TB patients' health. (benthamscience.com)
  • Anti Infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. (benthamscience.com)
  • The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. (benthamscience.com)
  • Although research into these drugs has focused on their effects on pain and fever management, until now, their impact on the treatment of infectious diseases specifically was unclear. (scitechdaily.com)
  • Professor Andrew McLachlan said on the positive side, the findings provide new insights for further research to evaluate these commonly used medicines, which could be repurposed to improve outcomes for people undergoing treatment for infectious diseases. (scitechdaily.com)
  • In May 2016, the FDA granted Qualified Infectious Disease Product (QIDP) and Fast Track Designation to CD101 topical for the treatment of VVC and the prevention of RVVC. (biospace.com)
  • How can CVM encourage the development of antimicrobial drugs consistent with the principles of antimicrobial stewardship for the treatment of infectious diseases in companion animals for which there are no FDA-approved animal drugs? (climatechangelegalblogarchive.com)
  • Aetna considers the use of chelation therapy experimental and investigational in the prevention and treatment of cancer, cardiovascular disease (e.g., atherosclerotic cardiovascular disease , coronary artery disease, individuals who had a myocardial infarction), neurodegenerative diseases (e.g. (aetna.com)
  • For HBsAg-negative/HBcAb-positive patients recommendations differ, but in case of combination treatment should follow those for other, particularly anti-CD20, agent. (bvsalud.org)
  • With the urgent need for new treatments for COVID-19 and the declining efficacy of some antimicrobial agents due to resistance, now more than ever we need medicines which can maintain or enhance the efficacy of anti-infective drug treatments, said Professor McLachlan, the Head of School and Dean of Pharmacy at the University of Sydney. (scitechdaily.com)
  • With the ongoing global concern over emerging viral diseases and the impact of pandemics, the demand for effective antiviral therapies continues to rise. (pharmaoffer.com)
  • Astellas already has experience in the development and marketing of Anti-Infective agents through the worldwide launch of its antifungal agent Mycamine ® (micafungin), and in November 2009, the launch in the United States of an antibiotic VIBATIV TM (telavancin). (astellas.com)
  • In the new world where communicable diseases are taking center stage, having solid infectious disease pharmacology knowledge is essential for patient care. (fcarvturin.it)
  • Communicable diseases and related conditions remain an important challenge to public health, responsible for the death of an estimated 17 million people a year and for disabilities ranging from chronic anaemia, malnutrition and wasting to paralysis, mental retardation and elephantiasis. (who.int)
  • The epidemiology and demography of communicable diseases, once thought to be relatively stable, are instead evolving in tandem with other global trends. (who.int)
  • The above challenges underscore the need for all countries to monitor, prevent, and control the spread of communicable diseases and to care effectively for those who are infected. (who.int)
  • They also highlight the need for global leadership, global and national advocacy, and improved international cooperation in tackling communicable diseases. (who.int)
  • The Communicable diseases cluster is working to reduce the impact of communicable diseases worldwide by leading the global effort in surveillance, prevention, control and research. (who.int)
  • tracking epidemic and emerging diseases and anti-infective drug resistance, and locating communicable diseases geographically within countries, regionally and globally. (who.int)
  • C ensuring sustainable, cost-effective control of endemic communicable diseases at country level. (who.int)
  • C eliminating endemic communicable diseases as public health problems through intensified efforts to apply cost-effective strategies, during a fixed period of time, to decrease the incidence and prevalence of selected communicable diseases, or, in the case of eradication, to rid the world permanently of their presence. (who.int)
  • To automate the identification of 6 pulmonary diseases (including pneumonia) through analysis of radiology reports. (cdc.gov)
  • But even where therapies against infectious diseases had been available, an additional threat has gained world-wide attention: antimicrobial resistance (AMR). (lu.se)
  • They can be new anti-TB drugs or agents for HDT. (benthamscience.com)
  • This volume is essential for general readers, healthcare professionals, researchers, and academicians actively involved in research on infectious diseases and anti-infective therapeutic drugs. (benthambooks.com)
  • This chapter aims to discuss the anti-infective agents to broaden the understanding of the fundamental concepts, practical applications of the drugs prescribed and the necessary care for pregnant women. (eurekaselect.com)
  • The anti-infective drugs market will jump to $66 billion by 2013, according to a recently published report. (malaria.com)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs). (rxwiki.com)
  • Their purpose is to improve the health of individuals, communities, and society by promoting excellence in patient care, education, research, public health, and prevention relating to infectious diseases. (ubc.ca)
  • In 2019, the Executive Guideline Steering Group (GSG) for the World Health Organization (WHO) maternal and perinatal health recommendations prioritized updating the then current WHO recommendations on antiplatelet agents for the prevention of pre-eclampsia. (bvsalud.org)
  • There is an urgent need for an integrated approach to disease surveillance, prevention and control. (who.int)
  • To provide differential diagnoses for patients with diseases of infectious etiology. (cdc.gov)
  • Therefore, understanding the regulation of these enzymes is essential for developing effective therapeutic strategies for infectious and inflammatory diseases. (hilarispublisher.com)
  • It is speculated that when the bowel flora colonies become dysbiotic, autoimmune conditions such as inflammatory bowel disease can result. (jontristermd.com)
  • The main impact of chronic Chagas disease corresponds primarily to the occurrence of chronic chagasic cardiopathy, and recognition and characterization of this has been the main stimulus for large-scale control interventions in the endemic countries since the 1950s. (eurekaselect.com)
  • Nowadays, Chagas disease affects 18 million people and is considered the most lethal endemic infectious disease in the Western Hemisphere. (eurekaselect.com)
  • National health systems improve endemic disease control through better planning and broader, more effective use of available tools and resources. (who.int)
  • A myriad of agents can potentially be transmitted through blood transfusions, including bacteria, viruses, and parasites. (medscape.com)
  • Bacteria or, for that matter, any infective agent that potentially evades the sterility of the transfusion loop can come from the donor's blood or skin or from a contaminated environment. (medscape.com)
  • To date, there is no NHP efficacy model for studying the microbiome, in particular in the context of infectious human diseases. (pharmiweb.com)
  • Eriodontal regenerative medicine, scientists will require to examine dual delivery of host modifiers or anti-infective agents to optimize the results of therapy. (achrinhibitor.com)
  • In addition to his primary appointment in Infectious Diseases, he will have a secondary appointment in Microbiology and Immunology Cancer Biology and be an integral member of the Carter Immunology Center. (virginia.edu)
  • Beginning as a silvatic enzoosis involving Trypanosoma cruzi and a range of small mammals and marsupials, human Chagas disease probably emerged as a sparse focal disease at different points in the Americas well before the Christian period. (eurekaselect.com)
  • In contrast, megaoesophagus seems a more specific marker of chronic Chagas disease, with a number of reports of its occurrence in various parts of Brazil, especially since the 18th century. (eurekaselect.com)
  • With its potential enzootic presence for over 90 million years, Chagas disease in humans has been documented in 9 thousand-year-old mummies from the Atacama Desert. (eurekaselect.com)
  • Lately, Chagas disease has shown exponential growth because European and African colonizers dwelling in huts infested by triatomines contaminated with T. cruzi were promptly infected. (eurekaselect.com)
  • Chagas disease is now a public health problem due to the detection of cases all around the world. (eurekaselect.com)
  • Intensive efforts are needed for diseases targeted for eradication and elimination, such as leprosy, lymphatic filariasis, dracunculiasis and Chagas disease. (who.int)
  • TB is one of the top ten causes of death in the world and it is highly prevalent, characterized by the constant occurrence of drug-resistant cases, and confounded by the incidence of respiratory diseases caused by nontuberculous mycobacteria (NTM). (benthamscience.com)
  • While these agents have been effective in treating infectious diseases, the overuse and misuse of these agents have led to the emergence of drug-resistant strains, which is a growing global health concern. (hilarispublisher.com)
  • To mitigate the emergence of drug resistance, it is essential to promote appropriate use of these agents, as well as invest in the development of new antiinfective agents and strategies for combating infectious diseases. (hilarispublisher.com)
  • The construction of a regional reference center, which includes a confined facility managed by Cynbiose, will allow NHP models to be manipulated for studying microbiota and carrying out infectious challenges. (pharmiweb.com)
  • Supported by its 15 years of expertise, Biofortis is making its resources and high-performance metagenomic analysis tools available to take on the major challenges of microbiota in infectious diseases. (pharmiweb.com)
  • La consommation et le coût des médicaments dans les services ont été estimés sur une période d'un mois en 2010 à l'aide du système de classification anatomique, thérapeutique et chimique et des doses thérapeutiques quotidiennes calculées pour 100 jours-patient. (who.int)
  • La consommation totale des agents antibactériens était de 414,1 doses thérapeutiques quotidiennes dans l'hôpital de Thabet et de 591,5 doses thérapeutiques quotidiennes dans l'hôpital de Rafidia. (who.int)
  • This emerging resistance intensifies the need for new antifungal agents. (biospace.com)
  • Ciara is an exceptional leader whose combined scientific expertise and business acumen will serve AWG well as the organization continues to champion the scientific, regulatory and economic needs of infectious disease companies working to address today's unspoken pandemic, antimicrobial resistance," said Dr. Loh. (antimicrobialsworkinggroup.org)
  • Cynbiose's partners for the CYNBIOME network are: ABL, AMA Research Solutions, Biose, Maat Pharma, Biofortis (Mérieux Nutrisciences Group), Viroscan3D and the BIOASTER academic research institutes, the laboratory CarMen, the International Center for Research in Infectious Diseases (CIRI), SFR Biosciences and the technological research platform Virnext. (pharmiweb.com)
  • Dr. Russo directly oversaw investigator-initiated research for a broad portfolio of anti-infectives, including daptomycin, fidaxomicin, ceftolozane/tazobactam, and tedizolid. (antimicrobialsworkinggroup.org)
  • This training grant, which has been continuously funded for 45 years, supports our Infectious Disease fellows' research training and uniquely graduate student training. (virginia.edu)
  • Therefore, the aim of the present chapter is to outline the world of anti- infective agents, along with their mechanism of action. (benthamscience.com)