• Equine infectious anemia virus (EIAV) is a member of the lentivirus genus in the Retroviridae family and is considered an animal model for HIV/AIDS research. (virosin.org)
  • EIAV has the simplest genome composition of all lentiviruses, making it an intriguing subject for understanding how the virus employs its limited viral proteins to overcome restriction factors. (virosin.org)
  • In this review, we summarize the current literature on the interactions between equine restriction factors and EIAV. (virosin.org)
  • The features of equine restriction factors and the mechanisms by which the EIAV counteract the restriction suggest that lentiviruses employ diverse strategies to counteract innate immune restrictions. (virosin.org)
  • Equine Infectious Anemia Virus (EIAV) is considered a barrier to the equine industry as it causes a persistent infection in horses. (ispecjournal.com)
  • The lentivirus equine infectious anemia virus (EIAV) encodes the small protein S2, a pathogenic determinant that is important for virus replication and disease progression in horses. (unitn.it)
  • EIAV-derived vectors devoid of S2 are less susceptible than HIV-1 to the inhibitory effect of both human and equine SERINC5. (unitn.it)
  • EIAV (Equine Infectious Anemia Virus) est un rétrovirus, appartenant au genre lentivirus, qui infecte les équidés à travers le monde. (hal.science)
  • Nous avons décrit une atteinte pulmonaire interstitielle chez des chevaux infectés par le virus EIAV, associée à une expression de la capside dans les macrophages, les cellules endothéliales et les cellules épithéliales matures du poumon distal, non connues auparavant comme cellules cibles de l'infection. (hal.science)
  • In this paper, the authors describe a recombinant virus that contains several key EIAV proteins. (usda.gov)
  • This recombinant virus can be used to further examine the immune system responses to EIAV infection in horses. (usda.gov)
  • Cells infected with vaccinia viruses expressing the equine infections anaemia virus (EIAV) gag gene (Vgag) and gag plus 5¿ pol encoding protease (Vgag/PR) were evalused with monoclonal antibody to a p26 capsid protein linear epitope (QEISKFLTD). (usda.gov)
  • Human immunodeficiency virus (HIV) and equine infectious anemia virus (EIAV)-derived lentiviral vectors were constructed, with the human ABCA4 gene under the control of constitutive (CMV, EF1α) or photoreceptor-specific (Rho) promoters. (arvojournals.org)
  • FIV and HIV are closely related to other lentiviruses including Simian Immunodeficiency Virus (SIV) and Equine Infectious Anemia Virus (EIAV), each of which is a species-specific virus using analogous proteins in the viral life cycle. (ucl.ac.uk)
  • Despite testing and measures to eradicate the equine infectious anemia virus, EIAV, more than 500 new cases are identified each year in the U.S. (gulfcoastequinevet.com)
  • Infección vírica de los caballos producida por el VIRUS DE LA ANEMIA INFECCIOSA EQUINA, ( EIAV). (bvsalud.org)
  • The C.E. Kord Animal Health Diagnostic Laboratory offers a full line of equine disease testing, including West Nile virus, equine infectious anemia, equine herpes virus, equine protozoal myeloencephalitis, eastern equine encephalitis, and equine influenza virus. (tn.gov)
  • It also includes protection against equine herpes virus. (besthorserider.com)
  • Emergence of CD134 cysteine-rich domain 2 (CRD2)-independent strains of feline immunodeficiency virus (FIV) is associated with disease progression in naturally infected cats. (medscape.com)
  • 4. Susceptibility of feline immunodeficiency virus/human immunodeficiency virus type 1 reverse transcriptase chimeras to non-nucleoside RT inhibitors. (nih.gov)
  • 5. Chimeric HIV-1 and feline immunodeficiency virus reverse transcriptases: critical role of the p51 subunit in the structural integrity of heterodimeric lentiviral DNA polymerases. (nih.gov)
  • The FIV RT-epPCR comprises a series of specific targeted reagents designed for Feline immunodeficiency virus detection by using RT-epPCR. (geneticpcr.com)
  • Feline immunodeficiency virus is a single-stranded negative-sense RNA virus belonging to the Lentivirus genus. (geneticpcr.com)
  • Amongst non-human vertebrates, Feline Immunodeficiency Virus (FIV) infection is perhaps the closest biological model of HIV infection with an analogous late-stage AIDS-type progression. (ucl.ac.uk)
  • Since this is a blood borne disease, a horse that has already been tested positive for equine infectious anemia, should never be bred, as this may only result in offspring that are infected, even if the mare is able to have a full term pregnancy that is normal in every way. (pethealthandcare.com)
  • On July 25, a horse in Stettler County No. 6, Alberta, was confirmed positive for equine infectious anemia (EIA). (equusmagazine.com)
  • Similar kidney lesions may be caused by different etiologies, including other viruses, such as infectious bursal disease virus (the cause of Gumboro disease) and toxins (for instance ochratoxins of Aspergillus ochraceus), and dehydration. (datexis.com)
  • Three cases of Eastern Equine Encephalitis have been reported in horses in the Parry Sound region of Ontario. (horsewelfare.ca)
  • Eastern Equine Encephalitis (EEE) and Western Equine Encephalitis (WEE) are both neurological diseases spread to horses and humans from infected wild birds and rodents via blood sucking mosquitos. (horsewelfare.ca)
  • Information about a new EEE case confirmed in ON can be found here: https://cahss.ca/cahss-tools/disease-alerts/eastern-equine-encephalitis-in-ontario-july-28-2023?l=en-us. (horsewelfare.ca)
  • His lab currently studies several enveloped RNA viruses that cause significant diseases in humans and livestock, including zoonotic influenza A virus, HIV and emerging infectious disease agents such as Zika virus and influenza D virus. (theplaidhorse.com)
  • Till date there is no equine infectious anemia vaccine . (pethealthandcare.com)
  • Past major contributions to virology include a classification change of equine rhinovirus 1 and, in conjunction with several researchers, including Charles Issel at the Gluck Center, the development of the first genetically engineered live attenuated equine infectious anemia virus vaccine, which resulted in a U.S. patent on EIA vaccine and diagnostics. (theplaidhorse.com)
  • Like the human immunodeficiency virus (HIV), there is neither cure nor vaccine for EIA. (cowboycountrymagazine.com)
  • This vaccine gives your horse protection against four different transmissible equine diseases. (besthorserider.com)
  • Is The Equine 4 Way Vaccine The Right One For Your Horse? (besthorserider.com)
  • Serological surveillance for maedi-visna virus and caprine arthritis-encephalitis virus in Northern Ireland. (nih.gov)
  • The lentiviruses: maedi/visna, caprine arthritis-encephalitis, and equine infectious anemia. (nih.gov)
  • Of the 4 persons with documented Hendra virus infection, 2 recovered from influenza-like illnesses (ILIs) ( 2 , 5 ) and 2 died, 1 from respiratory failure ( 2 ) and 1 from encephalitis 13 months after initial aseptic meningitis ( 3 ). (cdc.gov)
  • We report 2 additional human cases of Hendra virus encephalitis, 1 fatal, in veterinary workers associated with this equine outbreak. (cdc.gov)
  • In the western United States, test for Rocky Mountain spotted fever, Powassan virus, Colorado tick fever, western equine encephalitis virus, West Nile virus, and St. Louis encephalitis virus. (medscape.com)
  • Bayesian inference reveals ancient origin of simian foamy virus in orangutans. (cdc.gov)
  • The n-glycosylation of equine tetherin affects antiviral activity by regulating its subcellular localization. (virosin.org)
  • Additionally, his HIV research during his time at Panacos Pharmaceuticals resulted in discovering the first antiviral drug for equines. (theplaidhorse.com)
  • It's important that you get a veterinarian to examine the horse at the first signs of illness as the horse's condition can deteriorate rather rapidly and its important to begin equine pneumonia treatment promptly. (pethealthandcare.com)
  • A 33-year-old man (equine veterinarian) at the clinic had a 2-day history of an ILI (fever, myalgia, and headache) in mid-July 2008. (cdc.gov)
  • NASHVILLE - The state veterinarian is advising horse owners of four cases of equine infectious anemia (EIA) in Middle Tennessee. (tn.gov)
  • She completed an advanced internship at The Equine Medical Center of Ocala and is currently the owner and practicing veterinarian at Polk Equine. (centralfloridaagnews.com)
  • For more information about EIA, ask your equine veterinarian for "Equine Infectious Anemia: The Only Protection if Prevention," a brochure provided by the AAEP in conjunction with Educational Partner Bayer Animal Health. (gulfcoastequinevet.com)
  • The 5-way horse vaccination is the one most commonly administered by equine veterinary practitioners. (besthorserider.com)
  • A species of LENTIVIRUS , subgenus equine lentiviruses ( LENTIVIRUSES, EQUINE ), causing acute and chronic infection in horses. (nih.gov)
  • Under this heading, there are four helpful subsections, Contagious Equine Metritis (CEM), Equine Movement Requirements, Florida's Reportable Equine Disease Map, and Marks and Brands Registration. (centralfloridaagnews.com)
  • Piroplasmas (Theileria and Babesia) are tick-borne protozoa that cause piroplasmosis, which is a disease characterized by hemolytic anemia, in domestic animals, such as cattle and horses. (obihiro.ac.jp)
  • Piroplasmosis is one of the major diseases, leading to serious economic damage to the cattle and equine industry. (obihiro.ac.jp)
  • However, there are no effective methods to control the bovine and equine piroplasmosis. (obihiro.ac.jp)
  • The International Organization for Animal Health (OIE) has accredited our laboratory as OIE Reference Laboratory for bovine babesiosis and equine piroplasmosis. (obihiro.ac.jp)
  • At the NRCPD, my research interest focuses on bovine and equine piroplasmosis, which are diseases caused by Babesia and Theileria parasites and characterized by hemolytic anemia. (obihiro.ac.jp)
  • The new group was recently approved by the International Committee on Taxonomy of Viruses and the virology community. (theplaidhorse.com)
  • In the near future, we would like to develop an internationally recognized equine virology program with strong integration of both basic science and translational research, and serve the equine community to improve the health and well-being of horses," he said. (theplaidhorse.com)
  • She will serve as an assistant research professor with a focus on contributing to the ongoing research program in equine virology, with a primary focus on the influenza viruses. (theplaidhorse.com)
  • Hendra virus has caused serious respiratory infections in horses and respiratory and neurologic infections in humans. (cdc.gov)
  • Horses with equine infectious anemia virus, like humans infected with human immunodeficiency virus (HIV), have a life-long infection, although many infected horses remain clinically normal for long periods of time. (usda.gov)
  • An understanding of the mechanisms by which the horse controls the virus may be helpful in designing control measures to extend the life of humans infected with HIV. (usda.gov)
  • The virus is a relative of HIV (AIDS) in humans. (trailswesttrailers.com)
  • During his time at South Dakota State University, Li's group discovered novel zoonotic influenza viruses with bovine as a primary reservoir, resulting in a proposal to name the group of new influenza viruses as influenza D type. (theplaidhorse.com)
  • In more recent years, we have been collaborating with Dr. Thomas Chambers' group in equine influenza as well as the influenza D virus that we discovered in U.S. bovine and pig herds. (theplaidhorse.com)
  • This kit is for fluorescent detection of specific DNA nucleic acid fragments of bovine nodular skin disease virus. (hwtai.com)
  • The kit uses specific primers for bovine nodular skin disease virus, and uses nucleic acid amplification and fluorescently labeled probes to detect viral nucleic acids. (hwtai.com)
  • In this manner, the virus replicates itself quickly, taking over the normal cells of the body and causing illness and disease. (pethealthandcare.com)
  • There is no credible evidence that the lentivirus that causes equine infectious anaemia (EIA) replicates in invertebrates. (lsu.edu)
  • A recent Hendra virus outbreak at a veterinary clinic in Brisbane, Queensland, Australia, involved 5 equine and 2 human infections. (cdc.gov)
  • In contrast to previous equine outbreaks, horses in this outbreak showed predominantly neurologic (ataxia, head tilt, limb paresis), rather than respiratory, symptoms ( 1 ). (cdc.gov)
  • Saskatchewan and other regions of Western Canada are in the midst of the largest equine infectious anemia (EIA) outbreak the area has seen in years, involving more than 70 horses and 22 different properties thus far in 2012. (cowboycountrymagazine.com)
  • EIA is a potentially fatal blood borne infectious viral disease that produces a persistent infection among equids nearly worldwide. (progeq.com)
  • Equine infectious anemia is a viral disease that attacks horses' immune systems. (equusmagazine.com)
  • Some of the more severe equine pneumonia symptoms include abdominal breathing, nostril flaring and cyanosis. (pethealthandcare.com)
  • To date, I have conducted the research on several microorganisms causing severe infectious diseases in animals. (obihiro.ac.jp)
  • Search, retrieve and analyze Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequences in NCBI Virus . (nih.gov)
  • Aplastic anemia (moderate to severe) in patients unsuitable for bone marrow transplantation. (nih.gov)
  • equine influenza virus (EIV) H3N8, equine herpesvirus 1 and 4 or antibodies against erythrocyte antigens (which causes severe anemia in the receiving horse). (hatunalab.com)
  • Equine infectious anemia quarantine is one of the best methods to make sure that your horses do not get infected from an already infected horse. (pethealthandcare.com)
  • and negative PCR results for respiratory viruses, including influenza, on a nasopharyngeal aspirate (NPA) specimen. (cdc.gov)
  • Their combined expertise in viral respiratory diseases will both complement and enhance the equine infectious disease program at the Gluck Center," said David Horohov, chair of the Department of Veterinary Science, director of the Gluck Equine Research Center and Jes E. and Clementine M. Schlaikjer Endowed Chair. (theplaidhorse.com)
  • Other diseases such as mycoplasmosis by Mycoplasma gallisepticum (chronic respiratory disease), Newcastle disease by mesogenic strains of Newcastle diseases virus (APMV-1), avian metapneumovirus, infectious laryngotracheitis, avian infectious coryza in some stages may clinically resemble IB. (datexis.com)
  • Equine infectious anemia in mules, donkeys, and horses: Epidemiologic studies in the different geographic regions of Turkey. (ispecjournal.com)
  • The equine family, covering horses, mules and donkeys, have all been of great help to the development of civilization over the centuries. (pethealthandcare.com)
  • RESEARCH OBJECTIVES Background Progress in the development of models of viral-associated malignancies of large domesticated animals has been hampered due to the indolent nature of the disease course, the limited number of livestock animals that develop malignancies, and the diversity of viruses that can induce neoplasia or play a role as an etiologic co-factor. (nih.gov)
  • Foodborne poisoning is any illness resulting from food contaminated with a disease-causing agent as pathogenic bacteria, viruses, or parasites. (geneticpcr.com)
  • When you have agriculture or equine disease questions, visit the Florida Department of Agriculture and Consumer Services website, FreshFromFlorida.com . (centralfloridaagnews.com)
  • The Reportable Equine Disease Map is an interactive way to look at disease occurrence within the state. (centralfloridaagnews.com)
  • Since the discovery of the Human Immunodeficiency Virus (HIV) in 1984 this single disease has caused 25 million deaths worldwide, clearly highlighting the unique challenge in this research area. (ucl.ac.uk)
  • The University of Kentucky Gluck Equine Research Center recently welcomed two accomplished researchers into its infectious disease program. (theplaidhorse.com)
  • Feng Li has been named the William Robert Mills Chair in Equine Infectious Disease and Dan Wang joins the department as a virologist. (theplaidhorse.com)
  • I am very pleased and honored to become a part of the infectious disease research team at the Gluck Equine Research Center. (theplaidhorse.com)
  • EIA is an incurable infectious disease of horses that is spread by biting insects such as flies. (cowboycountrymagazine.com)
  • These are simple blood tests that will help detect infection, electrolyte imbalance, anemia, dehydration, organ dysfunction and chronic disease. (progeq.com)
  • Horses face a disease threat called equine infectious anemia virus. (veterinarianlisting.com)
  • EDCC Health Watch is an Equine Network marketing program that utilizes information from the Equine Disease Communication Center (EDCC) to create and disseminate verified equine disease reports. (equusmagazine.com)
  • The EDCC is an independent nonprofit organization that is supported by industry donations in order to provide open access to infectious disease information. (equusmagazine.com)
  • Equine Infectious Anemia (EIA) is a potentially fatal disease that threatens the world's horse, donkey and mule populations. (gulfcoastequinevet.com)
  • Most 4-way horse vaccines will contain the last three components, with either equine influenza or West Nile virus as the fourth disease. (besthorserider.com)
  • Cases may be referred to the US Centers for Disease Control and Prevention at Fort Collins, Colorado or the US Army Medical Research Institute of Infectious Diseases in Fort Detrick, Md. (medscape.com)
  • The usefulness of ATGAM has not been demonstrated in patients with aplastic anemia who are suitable candidates for bone marrow transplantation or in patients with aplastic anemia secondary to neoplastic disease, storage disease, myelofibrosis, Fanconi's syndrome, or in patients known to have been exposed to myelotoxic agents or radiation. (nih.gov)
  • Comparative analysis of protein evolution in the genome of pre-epidemic and epidemic Zika virus. (cdc.gov)
  • In the 2016 Zika virus (ZIKV) pandemic, a previously unrecognized risk of birth defects surfaced in babies whose mothers were infected with Asian-lineage ZIKV during pregnancy. (ocularservices.com)
  • Journal of Equine Veterinary Science, 25: 439-441. (ispecjournal.com)
  • Equine Veterinary Journal, 29(3): 178-185. (ispecjournal.com)
  • Emergence of Hendra virus is a serious medical, veterinary, and public health challenge. (cdc.gov)
  • In early July 2008, a veterinary practice (clinic) in Thornlands, Queensland, was quarantined after 2 acutely ill horses were provisionally diagnosed with Hendra virus infection. (cdc.gov)
  • BIO: Dr. Katie Hennessy graduated from the University of Illinois College of Veterinary Medicine in 2008 with a degree in large animal health and equine medicine. (centralfloridaagnews.com)
  • and New World arenaviruses, and negative for Machupo virus by ELISA antigen capture. (cdc.gov)
  • For virus characterization, recent methodology using genomic amplification (PCR) and sequencing of products, will enable very precise description of strains, according to the oligonucleotide primers designed and target gene. (datexis.com)
  • Maan NS, Maan S, Nomikou K, Belaganahalli MN, Bachanek-Bankowska K, Mertens PP. Serotype specific primers and gel-based rt-PCR assays for 'typing' african horse sickness virus: identification of strains from Africa. (medscape.com)
  • The occurrence of neoplastic sequelae in retrovirus-infected animals supports the view that these viruses may be directly or indirectly involved in the etiology of malignancies. (nih.gov)
  • We currently study several enveloped RNA viruses, including influenza and retrovirus. (theplaidhorse.com)
  • There has also been a recent report on a transforming equine retrovirus isolated from a sarcoma. (nih.gov)
  • It is characterized by intermittent fever, weakness, and anemia. (bvsalud.org)
  • Yellow fever in the Gambia, 1978--1979: epidemiologic aspects with observations on the occurrence of orungo virus infections. (medscape.com)
  • Hendra virus RNA was detected by reverse transcription-PCR (RT-PCR) in serum and NPA specimens. (cdc.gov)
  • serum samples collected on days 3--7 also were negative for IgM and IgG antibody to YF virus. (cdc.gov)
  • Serum specimens collected on days 4, 5, and 7 of illness and a postmortem liver sample were positive for YF virus RNA by RT-TaqMAN PCR tests. (cdc.gov)
  • Virus isolation was attempted by inoculation of serum samples onto Vero and AP-61 cells in tissue culture, and by inoculation of postmortem plasma onto Vero cells in tissue culture and intracerebrally into suckling mice. (cdc.gov)
  • The role of N-glycans of HIV-1 gp41 in virus infectivity and susceptibility to the suppressive effects of carbohydrate-binding agents. (medscape.com)
  • Stabilization of the β-hairpin in Mason-Pfizer monkey virus capsid protein- a critical step for infectivity. (medscape.com)
  • HIV-1 Vif inhibits G to A hypermutations catalyzed by virus-encapsidated APOBEC3G to maintain HIV-1 infectivity. (medscape.com)
  • 2014. The cloning of equine trim5α gene and the anti-equine infectious anemia virus activity of the protein. (virosin.org)
  • Like Nef, S2 excludes SERINC5 from virus particles and requires an ExxxLL motif predicted to recruit the clathrin adaptor, Adaptor protein 2 (AP2). (unitn.it)
  • Triptolide inhibits human immunodeficiency virus type 1 replication by promoting proteasomal degradation of Tat protein. (medscape.com)
  • Both recombinant viruses expressed Gag precursor protein (55K) whereas only Vgag/PR expressed a detectable Gag-Pol fusion protein (82K) with a functional protease, shown by subviral particles containing processed p26. (usda.gov)
  • When nucleic acid is added to Gag, the protein assembles into virus-like particles. (nih.gov)
  • Interestingly, unlike HIV-1 Gag protein, the Gag protein of the gammaretrovirus Moloney murine leukemia virus is rod-shaped in solution, just as it is in immature virus particles, and does not dimerize significantly in solution. (nih.gov)
  • First, an exquisitely specific recognition by the Gag polyprotein (the structural protein of the virus particle) selects the viral RNA for packaging during virus assembly. (nih.gov)
  • We are studying the mechanism by which the Gag protein recognizes and packages the genomic RNA of the virus during assembly in vivo. (nih.gov)
  • In Virus infections of equines, Vol. 6 of Virus infections of vertebrates. (ispecjournal.com)
  • Controlling EIA depends upon the identification of persistently infected equids by serological testing because other methods of identifying infective virus or viral genetic material are less accurate or impractical. (lsu.edu)
  • The battle between the viruses and restriction factors is actually a natural part of the viral replication process, which has been well studied in human immunodeficiency virus type 1 (HIV-1). (virosin.org)
  • The microRNA miR-29a is associated with human immunodeficiency virus latency. (medscape.com)
  • 1. Enzymatic properties of two mutants of reverse transcriptase of human immunodeficiency virus type 1 (tyrosine 181-->isoleucine and tyrosine 188-->leucine), resistant to nonnucleoside inhibitors. (nih.gov)
  • 2. Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138. (nih.gov)
  • 3. Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates. (nih.gov)
  • 11. [Studies of the resistance of the human immunodeficiency virus to azidothymidine. (nih.gov)
  • 12. Human immunodeficiency virus reverse transcriptase. (nih.gov)
  • 16. A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation. (nih.gov)
  • 17. Kinetics of different human immunodeficiency virus type 1 reverse transcriptases resistant to human immunodeficiency virus type 1-specific reverse transcriptase inhibitors. (nih.gov)
  • The identification and development of suitable animal models of viral neoplasia may aid in investigations of the mechanisms of cancer initiation and progression, ultimately providing a better understanding of the role of viruses in the etiology of human cancer. (nih.gov)
  • Circulating levels of the virus in an affected horse are low, however, so it is highly unlikely that a horse would be a source of infection for a human. (horsewelfare.ca)
  • Given high human immunodeficiency virus (HIV) burdens in regions where African-lineage ZIKV circulates, we evaluated whether pregnant rhesus macaques infected with simian immunodeficiency virus (SIV) have a higher risk of African-lineage ZIKV-associated birth defects. (ocularservices.com)
  • Our research group is particularly interested in understanding, treating and preventing animal infectious diseases caused by viral pathogens. (theplaidhorse.com)
  • Equine infectious anemia: uniform methods and rules effective. (ispecjournal.com)
  • METHODS: A retrospective analysis of 505 consecutive patients submitted to either Roux-en-Y Gastric Bypass or Sleeve Gastrectomy between January and December 2019 was performed. (bvsalud.org)
  • The quickest way to find it is to go to the ag department's home page and do a search for "Horse/Equine. (centralfloridaagnews.com)