Infections with respiratory syncytial virus. Medical search. Frequent questions

These infections include bronchiolitis, an inflammation of the small airways in the lung, and pneumonia , an infection of the lungs. (medlineplus.gov)
Generally, these findings are neither specific to RSV infection nor predictive of the course or outcome, except for the observation that infants who have the additional findings of atelectasis or pneumonia may have a more severe disease course. (medscape.com)
Overview of Pneumonia Pneumonia is acute inflammation of the lungs caused by infection. (msdmanuals.com)
RSV (and possibly hMPV) infection is suspected in infants and young children with bronchiolitis or pneumonia during RSV season. (msdmanuals.com)
Respiratory illnesses caused by RSV - such as bronchiolitis or pneumonia - usually last about a week, but some symptoms, such as a cough, can last several weeks. (kidshealth.org)
This is important because respiratory syncytial virus infection can lead to serious health complications, such as pneumonia and bronchiolitis, especially in young children. (consultantlive.com)
In more serious cases, RSV infections can lead to bronchiolitis or pneumonia. (healthline.com)
RSV infection primarily manifests as bronchiolitis or pneumonia and results in approximately 75,000 to 125,000 hospitalizations in the United States each year ( 1 ). (cdc.gov)
Bacterial infections contribute disproportionately to pneumonia mortality in developing countries. (who.int)
Although bacterial infections account for no more than 50% of cases of pneumonia, they cause nearly 70% of deaths due to pneumonia. (who.int)
Respiratory syncytial virus is the most common virus causing pneumonia, particularly in young infants, followed by influenza viruses. (who.int)
Deaths due to pneumonia that occur during the neonatal period and those that are associated with measles, pertussis and HIV infection are not included in this figure. (who.int)
vaccination, including use of vaccines against infection by Streptococcus pneumoniae and Haemophilus influenzae type b · case management of pneumonia in the community, health centres and hospitals · exclusive breastfeeding for the first six months of life · improvement of nutrition and prevention of low birth weight · control of indoor air pollution and provision of a healthy environment · prevention and management of HIV infection. (who.int)
Vaccination against Streptococcus pneumoniae and Haemophilus influenzae type b (Hib) infections has reduced the incidence of pneumonia in various settings by about 30% (range 20% to 37%) and 20% (range 12% to 55%), respectively. (who.int)
Pneumonia is a lung infection that can cause inflammation and a buildup of fluid and pus in the lung. (healthline.com)
RSV is a pathogen that infects the human respiratory tract, potentially leading to infections such as bronchiolitis and pneumonia. (gilead.com)

Only 10% (4/40) persons as an at-risk population for severe RSV disease of patients with RSV infection who were readmitted within might guide prioritization strategies for RSV vaccines 30 days had a positive swab specimen for the same virus at and therapeutics as they become available. (cdc.gov)
The current lack of understanding of the mechanisms by which antibodies can protect against RSV infection and disease or, alternatively, contribute to disease severity, hampers the design of safe and effective vaccines against this virus. (ru.nl)
Clinicians should also talk to their patients about other vaccines available this fall to help prevent respiratory infections. (cdc.gov)
They usually identify the candidate virus in February, and flu vaccines aren't ready to go until July, August, or September for the next flu season. (pharmacytimes.com)
If there's a virus that infects the chicken population and eggs are contaminated [or] they're in short supply, we can develop these cell-cultured, synthetically manufactured vaccines to help with the total supply of flu vaccine out there in the United States. (pharmacytimes.com)
Vaccines or candidate vaccines used to prevent infection with RESPIRATORY SYNCYTIAL VIRUSES. (bvsalud.org)

Available at https://www.acog.org/clinical/clinical-guidance/practice-advisory/articles/2023/09/maternal-respiratory-syncytial-virus-vaccination . (medscape.com)
Indication for immunoprophylaxis against severe RSV infection with nirsevimab, 2023-2024 season. (analesdepediatria.org)
In August 2023, the US Food and Drug Administration (FDA) approved Abrysvo for use in pregnant individuals to prevent lower respiratory tract disease and severe lower respiratory tract disease caused by respiratory syncytial virus in infants from birth through six months of age. (wikipedia.org)
Since September 2023, it is also indicated in the continental United States as seasonal protection during September through end of January for pregnant women as a one-time dose at 32 to 36 weeks gestation to prevent RSV-infection in infants younger than 6 months. (wikipedia.org)
DelveInsight, the leading market research and consulting company, has added a new report, Cytomegalovirus (CMV) Infection - Market Insights, Epidemiology and Market Forecast-2023, to its portfolio. (pr.com)

The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Advisory to notify clinicians and caregivers about increases in respiratory syncytial virus (RSV) activity across some parts of the Southeastern United States in recent weeks, suggesting a continued shift toward seasonal RSV trends observed prior to the COVID-19 pandemic. (cdc.gov)
When you're looking at an egg-based vaccine, you start with a candidate virus that's determined by the FDA, the CDC [Centers for Disease Control and Prevention], and the WHO [World Health Organization]. (pharmacytimes.com)
While most otherwise healthy people recover from the virus within a few weeks, the Centers for Disease Control and Prevention (CDC) estimates that up to 125,000 infants are hospitalized due to RSV infection in the United States each year. (gilead.com)

Respiratory syncytial virus and human metapneumovirus infections cause seasonal lower respiratory tract disease, particularly in infants and young children. (msdmanuals.com)
For more than 20 years, effective prophylaxis against RSV infection has been achieved in the populations defined as being at high risk of severe or very severe disease due to RSV-clearly defined by the Sociedad Española de Neonatología (Spanish Society of Neonatology)-with the administration of a monoclonal antibody, palivizumab, which is very costly and has a short half-life. (analesdepediatria.org)
The development of a new monoclonal antibody with a longer half-life and of demonstrated efficacy and safety, nirsevimab, presents the opportunity to offer passive immunoprophylaxis universally to all healthy newborns to prevent these forms of disease in the period that they are most at risk of severe lower respiratory tract infection, chiefly in the first year of life. (analesdepediatria.org)
Human respiratory syncytial virus (HRSV) is a major cause of lower respiratory tract disease in children and the elderly for which there is still no effective vaccine. (unina.it)
Because the extent to which protection demonstrated in rodent models will translate to humans is unclear, we have exploited the calf model of bovine RSV (BRSV) infection, which mimics HRSV disease in children more closely than do experimental models of unnatural laboratory hosts, to evaluate the safety and efficacy of the PanAd3-RSV vaccine. (unina.it)
We show that PanAd3-RSV alone and in combination with a modified vaccinia Ankara expressing the same HRSV antigens (MVA-RSV) induced neutralizing antibodies and cellular immunity in young seronegative calves and protected against upper and lower respiratory tract infection and pulmonary disease induced by heterologous BRSV challenge. (unina.it)
There was no evidence either of enhanced pulmonary pathology or of enhanced respiratory disease in vaccinated calves after BRSV challenge. (unina.it)
Infants, young children, and older adults, especially those with chronic medical conditions, are at increased risk of severe disease from RSV infection. (cdc.gov)
Viruses replicate inside host cells and can produce toxins that cause disease. (nature.com)
A mouse model identifies FcγRIIIa engagement on splenic macrophages as a driver of disease severity during dengue infection. (nature.com)
Respiratory syncytial virus vaccine is indicated for active immunization for the prevention of lower respiratory tract disease caused by respiratory syncytial virus in people 60 years of age and older. (wikipedia.org)
This vaccine induced a phenomenon that came to be known as vaccine-associated enhanced respiratory disease, in which children who had not previously been exposed to RSV and were subsequently vaccinated would develop a severe form of RSV disease if exposed to the virus itself, including fever, wheezing, and bronchopneumonia. (wikipedia.org)
This model closely mirrors human RSV disease and affords a unique opportunity to study interepithelial cell interactions, cytokine responses from cells of different donors, and ciliary activity of live cells undergoing RSV infection. (nih.gov)
Infections with RSV are so common, especially in children, that many people are not tested for the virus unless they are at risk of more severe disease. (healthline.com)
Respiratory syncytial virus (RSV), the most common cause of severe lower respiratory tract disease among infants and young children, typically infects persons by age 2 years and can cause subsequent infections throughout life ( 1 ). (cdc.gov)
Persons at increased risk for severe disease or death include premature infants, older adults, and persons of any age with compromised respiratory, cardiac, or immune systems ( 2,3 ). (cdc.gov)
Dr. Casola's research efforts include investigating the pathogenesis of respiratory diseases caused by human metapneumovirus (hMPV), using molecular virology and animal model approaches, to investigate hMPV-induced lung disease and test novel antivirals and therapeutic agents. (utmb.edu)
Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Epstein-Barr Virus (HHV-4) Infections - Drugs In Development, 2021, provides an overview of the Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) pipeline landscape.Epstein-Barr virus (EBV) or human herpes virus 4 virus is a member of the Herpesviridae family. (marketresearch.com)
Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Epstein-Barr Virus (HHV-4) Infections - Drugs In Development, 2021, provides comprehensive information on the therapeutics under development for Epstein-Barr Virus (HHV-4) Infections (Infectious Disease), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. (marketresearch.com)
The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.The Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) pipeline guide also reviews of key players involved in therapeutic development for Epstein-Barr Virus (HHV-4) Infections and features dormant and discontinued projects. (marketresearch.com)
Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. (marketresearch.com)
The pipeline guide provides a snapshot of the global therapeutic landscape of Epstein-Barr Virus (HHV-4) Infections (Infectious Disease). (marketresearch.com)
The pipeline guide reviews pipeline therapeutics for Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) by companies and universities/research institutes based on information derived from company and industry-specific sources. (marketresearch.com)
The pipeline guide reviews key companies involved in Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) therapeutics and enlists all their major and minor projects. (marketresearch.com)
The pipeline guide evaluates Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. (marketresearch.com)
The BLA is based on positive data from a prespecified interim analysis of the pivotal AReSVi-006 ( A dult R espiratory S yncytial V irus) phase III trial, which showed high overall vaccine efficacy against RSV lower respiratory tract disease (LRTD) in adults aged 60 years and older. (gsk.com)
Coronavirus Disease 2019 (COVID-19) is a fatal lung infection caused by the novel coronavirus named Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which has influenced millions of people globally since its onset. (frontiersin.org)
virus disease (COVID-19) pandemic. (who.int)

Most cases of respiratory syncytial virus infection are mild and don't need medical treatment. (kidshealth.org)
As most American parents already know, cases of respiratory syncytial virus (RSV), a common illness of childhood, are surging this year. (blackdoctor.org)

A total of 4% (7/158) of adults given untreated chronic medical conditions, and higher rates a diagnosis of RSV infection died during hospitalization, of mental health issues and substance use ( 5 ). (cdc.gov)
We sought to determine whether increased hospital hospitalized with RSV infections versus those with in- readmission after hospitalization for RSV infection had fluenza in an urban medical center serving a region that other potential explanatory factors. (cdc.gov)
Updated guidance for palivizumab prophylaxis among infants and young children at increased risk of hospitalization for respiratory syncytial virus infection. (medscape.com)
Palivizumab Prophylaxis in Infants and Young Children at Increased Risk of Hospitalization for Respiratory Syncytial Virus Infection. (medscape.com)
Infection by respiratory syncytial virus (RSV) is the most common cause of hospital admission in infants aged less than 1 year in Spain, and severe forms requiring hospitalization in newborns and infants aged less than 3 months and lower respiratory tract infections in infants resulting a high volume of primary care and emergency department visits are particularly frequent. (analesdepediatria.org)
Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections and hospitalization in infants under 1 year of age and there is currently no market-approved vaccine available. (ru.nl)
Respiratory syncytial virus (RSV) is a frequent cause of hospitalization among infants. (nih.gov)
The main outcomes of interest in this study were all-cause mortality, respiratory syncytial virus-related hospitalization, respiratory syncytial virus-related infection, drug-related adverse events, intensive care unit admission, supplemental oxygen use, and mechanical ventilation use. (consultantlive.com)
With regard to the rate of RSV-related hospitalization and RSV infection, we did not find significant subgroup differences between patients with and without comorbidities. (consultantlive.com)
In young adults, lung function abnormalities may be associated with RSV infection which required hospitalization in infancy. (nih.gov)

Defining the Epidemiology and Burden of Severe Respiratory Syncytial Virus Infection Among Infants and Children in Western Countries. (medscape.com)
The seasonal epidemiology of hMPV appears to be similar to that of RSV, but the incidence of infection and illness appears to be substantially lower. (msdmanuals.com)
Systematic review and meta-analysis of respiratory syncytial virus infection epidemiology in Latin America. (bvsalud.org)

RSV remains important viral etiological agent causing influenza-like illness and severe acute respiratory infections especially among infants in Morocco. (who.int)
A comparison of influenza and respiratory syncytial virus infections among infants admitted to hospital with acute respiratory infections. (docksci.com)
Respiratory syncytial virus (RSV) is the leading cause of hospitalizations among infants. (sharecare.com)

Homeless persons experience with RSV infection were admitted to the intensive care unit higher rates of illness and death compared with the gen- (ICU), readmitted within 30 days, and received any anti- eral population, partly because of infectious diseases microbial drug compared with patients hospitalized with from lack of access to sanitation, crowding in shelters, influenza (Table 2). (cdc.gov)
World Health Organization Influenza-Like Illness Underestimates the Burden of Respiratory Syncytial Virus Infection in Community-Dwelling Older Adults. (ox.ac.uk)
BACKGROUND: Respiratory syncytial virus (RSV) surveillance is heavily dependent on the influenza-like illness (ILI) case definition from the World Health Organization (WHO). (ox.ac.uk)
Respiratory syncytial (sin-SISH-ul) virus (RSV) is a major cause of respiratory illness in children. (kidshealth.org)
The immune system helps to destroy viruses, but antiviral immune responses can also cause tissue damage and illness. (nature.com)
Chickenpox is a common childhood illness caused by a virus. (kidshealth.org.nz)
Respiratory syncytial virus (RSV) infection is a common respiratory illness caused by a virus. (cattco.org)
IL18, but neither IFNγ nor IL12 was found in significantly greater concentrations in subjects with mild, nonhypoxic forms of bronchiolitis than in those with upper respiratory illness alone or hypoxic bronchiolitis. (utmb.edu)
Little is known about the incidence of infection and type of illness caused by influenza viruses in infants. (docksci.com)
BACKGROUND: Respiratory syncytial virus (RSV) is an important cause of respiratory illness worldwide, however, burden data on mother-infant pairs remain sparse in sub-Saharan Africa where HIV is prevalent. (itg.be)
METHODS: We enrolled pregnant women (≤20 weeks gestation) and followed them and their newborns weekly for up to 3-6 months post-partum, to document cases of acute respiratory illness (ARI). (itg.be)
CONCLUSION: HIV-infection may increase the risk of RSV illness among pregnant women. (itg.be)
We evaluated the impact of maternal HIV infection on the burden of RSV among mothers and their infants in western Kenya.METHODS: We enrolled pregnant women (≤20 weeks gestation) and followed them and their newborns weekly for up to 3-6 months post-partum, to document cases of acute respiratory illness (ARI). (itg.be)
An RSV infection usually causes a mild, cold-like illness that goes away in one to two weeks. (clevelandclinic.org)

Respiratory syncytial virus (RSV) (see the image below) is the leading cause of lower respiratory tract infections (LRTIs) in infants and young children. (medscape.com)

But it can cause serious lung infections, especially in infants, older adults, and people with serious medical problems. (medlineplus.gov)
Because ILI includes fever in its syndromic case definition, its ability to accurately identify acute respiratory tract infections (ARTI) caused by RSV in older adults is uncertain. (ox.ac.uk)

Given Gilead's scientific and clinical expertise in virology, this partnership provides a strong validation of the potential for MDT-637 to become an important therapeutic advance for those affected by RSV infection. (gilead.com)

GSK plc (LSE/NYSE: GSK) today announced that the US Food and Drug Administration (FDA) has accepted a Biologics License Application (BLA) and granted Priority Review for its respiratory syncytial virus (RSV) older adult vaccine candidate. (gsk.com)

Tests to check for complications in people with severe infection. (medlineplus.gov)
Severe RSV infection and complications can affect children and adults of any age, including those who are otherwise healthy. (clevelandclinic.org)

However, some infants, and people with weakened immune systems, can continue to spread the virus even after they stop showing symptoms, for as long as 4 weeks. (cdc.gov)
But sometimes infants and people with weakened immune systems can continue to spread the virus for as long as 4 weeks. (medlineplus.gov)
For protection against infection, young children mainly depend on their innate immune system and maternal antibodies. (ru.nl)
The interaction with Fc-receptors can lead to killing of virus-infected cells through a variety of immune effector mechanisms, including antibody-dependent cell-mediated cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP). (ru.nl)
After vaccination, spike-specific CD8 + T cells play an important part in the immediate immune response to breakthrough SARS-CoV-2 infection, whereas the B cell and neutralizing antibody responses come into effect 2 weeks after infection. (nature.com)
compared the humoral immune responses induced by MPXV infection and Smallpox vaccination. (nature.com)
In order to understand early events in the immune response to respiratory syncytial virus (RSV) infection, we studied the presence of various chemokines and cytokines in respiratory secretions of human infants with RSV infection. (utmb.edu)

GSK -3888550A is under development for the prevention of respiratory syncytial virus infections. (pharmaceutical-technology.com)
Prevention of nosocomial respiratory syncytial virus infection. (ox.ac.uk)
Because of this, Mingyao Sun Department of Intensive Care Unit, The First Hospital of Lanzhou University, and a team of investigators, compared the efficacy and safety of monoclonal antibodies for the prevention of respiratory syncytial virus infection in infants and children. (consultantlive.com)
Monoclonal Antibody for the Prevention of Respiratory Syncytial Virus in Infants and Children: A Systematic Review and Network Meta-analysis. (consultantlive.com)

Respiratory syncytial virus, or RSV, is a common respiratory virus. (medlineplus.gov)
Influenza (flu), COVID-19, and respiratory syncytial virus (RSV) are all common respiratory illnesses caused by different viruses. (healthline.com)

Maternal Respiratory Syncytial Virus Vaccination. (medscape.com)
We evaluated the impact of maternal HIV infection on the burden of RSV among mothers and their infants in western Kenya. (itg.be)
Chaves, Sandra S. / The impact of maternal HIV infection on the burden of respiratory syncytial virus among pregnant women and their infants, western Kenya . (itg.be)

Although comparable responses were observed, infection- or vaccination specific serological markers were identified enabling discrimination between vaccinated and infected individuals. (nature.com)
Some eighty percent of such children (vs. 5% of virus-exposed controls) were hospitalized, and two children died of lethal lung inflammatory response during the first natural RSV infection after vaccination of RSV-naive infants. (wikipedia.org)
In a recent webinar with CDC's Project Firstline and the American Medical Association (AMA), CDC Director Dr. Mandy Cohen discussed the impacts of the current respiratory virus season, the importance of vaccination, and the importance of effective risk communication to help built trust with the public. (cdc.gov)

A viral or bacterial infection or allergic reaction are the most common causes of conjunctivitis. (kidshealth.org.nz)
It isn't a bacterial infection. (clevelandclinic.org)
Unexpectedly, 8-oxoguanine DNA glycosylase1 (Ogg1) knockout mice show enhanced stimuli-driven IFN expression that confers increased resistance to viral and bacterial infections and allergen challenges. (lu.se)

What are the symptoms of respiratory syncytial virus (RSV) infections? (medlineplus.gov)
Healthcare personnel, childcare providers, and staff at long-term care facilities should stay home and not go to work when they have fever or symptoms of respiratory infection to reduce the spread of respiratory infections including RSV. (cdc.gov)

Respiratory Syncytial Virus Infection (RSV): Trends and Surveillance. (medscape.com)
Our data show significant promise for the use of oral fluid alone in RSV infection surveillance. (ox.ac.uk)
Nationally, the weekly percentage of positive detections reported to the National Respiratory and Enteric Virus Surveillance System (NREVSS), a national laboratory-based surveillance network, has remained below the season onset threshold of polymerase chain reaction (PCR) test positivity of 3.0% for 2 consecutive weeks. (cdc.gov)
We conducted a prospective study using sentinel-based influenza surveillance to detect RSV by real time PCR in patients with acute respiratory infections, enrolled during two seasons (2014/15, 2015/16). (who.int)
Further surveillance, is required to understand better the risk factors of RSV infections. (who.int)
Nous avons réalisé une étude prospective en recourant à la surveillance de la grippe basée sur des sites sentinelles dans le but de dépister le VRS grâce à la PCR en temps réel chez des patients souffrant d'infections respiratoires aiguës recrutés au cours de deux saisons (2014-2015 et 2015-2016). (who.int)
Une surveillance renforcée est indispensable pour mieux comprendre les facteurs de risque des infections à VRS. (who.int)
Using data reported to the National Respiratory and Enteric Virus Surveillance System (NREVSS), this report summarizes RSV temporal and geographic trends in the United States during the weeks ending July 8, 2006 - -June 30, 2007, and for the first 5 months of the current reporting season (the weeks ending July 7--November 24, 2007). (cdc.gov)

Respiratory syncytial virus is highly contagious. (kidshealth.org)
Respiratory syncytial virus is a common and highly contagious virus that can cause severe lower respiratory infections, especially in children under the age of 5. (consultantlive.com)
Respiratory syncytial virus (RSV) is a seasonal, highly contagious respiratory virus that often feels like a common cold. (clevelandclinic.org)

Effectiveness of antiviral treatment in human influenza A(H5N1) infections: analysis of a Global Patient Registry. (cdc.gov)
Broad-Range Antiviral Activity of Hydrogen Sulfide against Highly Pathogenic RNA Viruses. (utmb.edu)
Antiviral activity of ginseng extract against respiratory syncytial virus infection. (naturalnews.com)
FOSTER CITY, Calif. & MONMOUTH JUNCTION, N.J., Apr 20, 2011 (BUSINESS WIRE) -- Gilead Sciences, Inc. (Nasdaq: GILD) and MicroDose Therapeutx, Inc. today announced that the companies have entered into an exclusive worldwide license and collaboration agreement for the development and commercialization of MDT-637, MicroDose's inhalable small molecule antiviral fusion inhibitor for the treatment of respiratory syncytial virus (RSV). (gilead.com)
We believe this program aligns well with our expertise in both antiviral and respiratory drug development and we look forward to working with the MicroDose team to advance MDT-637 into clinical testing. (gilead.com)
In a mouse model of bronchiolitis induced by RSV infection, functional ablation of OGG1 by a small molecule inhibitor (TH5487) enhances IFN-λ production, decreases immunopathology, neutrophilia, and confers antiviral protection. (lu.se)

ABSTRACT Currently, respiratory syncytial virus (RSV) infection is identified in epidemiological studies by virus antigen or nucleic acid detection in combination with serology. (ox.ac.uk)
ABSTRACT Respiratory syncytial virus (RSV) is a leading cause of mortality and morbidity in young infants, little was known on its circulation types and patterns in Morocco. (who.int)

RSV is an RNA virus, and transmission occurs primarily via respiratory droplets when a person coughs or sneezes, or through direct contact with a contaminated surface. (cdc.gov)
It spreads through droplets containing the virus when an infected person coughs or sneezes. (kidshealth.org)
RSV spreads through respiratory droplets that leave your body when you cough or sneeze. (clevelandclinic.org)

Globally, the annual death rate from RSV is estimated at more than 160,000 and the clinical burden of RSV infection is comparable to that of influenza. (gilead.com)

Despite these limitations, this study provided valuable insights into potential preventive strategies for respiratory syncytial virus and can inform clinical decision-making for high-risk infants and children. (consultantlive.com)

The proportion of positive RSV infection was higher in patients hospitalized with acute respiratory infection compared to those with mild symptoms in out-patient clinics. (who.int)

Rapid-test sensitivity for novel swine-origin influenza A (H1N1) virus in humans. (cdc.gov)
It is one of the most common human viruses to cause cancer in humans and is associated with a wide range of human cancers originating from epithelial cells, lymphocytes and mesenchymal cells. (marketresearch.com)

Systemic cell-mediated and antibody responses in infants with respiratory syncytial virus infections. (microbiologyresearch.org)

Chest radiography is frequently obtained in children with severe RSV infection, but for the most part, typical findings are neither specific to RSV infection nor predictive of the course or outcome. (medscape.com)
Chest radiography is frequently obtained in children with severe RSV infection. (medscape.com)

Virus antigen within the lungs was found to be restricted essentially to the alveolar regions. (microbiologyresearch.org)
In addition, infection induced rapid interferon production within the lungs which was accompanied by an equally rapid rise in pulmonary natural killer (NK) cell cytotoxic activity. (microbiologyresearch.org)
IgG was the first class of virus-specific immunoglobulin to be detected in the lungs of infected animals after experimental infection. (microbiologyresearch.org)
Immunoglobulin class specific antibody response in serum, spleen, lungs and bronchioal- veolar washings after primary and secondary Sendai virus infection of germ free mice. (microbiologyresearch.org)
RSV is a common contagious virus affecting the lungs and breathing passages. (gsk.com)

Over the past several years, she has identified several inducible intracellular signaling pathways activated by respiratory syncytial virus (RSV) in airway epithelial cells with particular emphasis on the role of reactive oxygen species in RSV induced lung inflammation both in vitro and in vivo, using a mouse model of RSV infection. (utmb.edu)
Antioxidant mimetics modulate oxidative stress and cellular signaling in airway epithelial cells infected with respiratory syncytial virus. (utmb.edu)
We found that functional inhibition, genetic ablation, and inactivation by post-translational modification of OGG1 significantly augment IFN-λ expression in epithelial cells infected by human respiratory syncytial virus (RSV). (lu.se)

Each year, 4-5 million children younger than 4 years acquire an RSV infection, and more than 125,000 are hospitalized annually in the United States because of this infection. (medscape.com)
The impact of RSV infection is not limited to only young children. (medscape.com)
However, a laboratory diagnosis may facilitate hospital infection control by allowing segregation of children infected with the same virus. (msdmanuals.com)
For five children sampled repeatedly from birth, antibody profiles in oral fluid quite consistently tracked those in paired sera, and RSV infections were detected by rising titers of antibodies of at least one Ig class. (ox.ac.uk)
Most adults and older children have had an RSV infection. (medlineplus.gov)
Some children younger than 24 months at high risk for RSV infection get a shot with antibodies to RSV to protect them. (medlineplus.gov)
Both influenza virus and RSV infections were diagnosed most frequently in children under the age of one year, and diagnosed more frequently in males than females. (docksci.com)
Both infections occurred more often, but were not more severe, in children from a conurbation than in those from 'rural' areas. (docksci.com)
In the present study, all the children under 5 years old with acute respiratory infections who were admitted to either Bristol Childrens' Hospital or Southmead Hospital during two winters from a circumscribed population were examined for respiratory virus infections as part of a collaborative study by the MRC Laboratory Working Party on RS Virus Infections. (docksci.com)
Patients It was intended to investigate all children under 5 years old admitted with acute respiratory infections. (docksci.com)
Of the 444 children tested in 1974/5, 61 (14 %) had proved infections with influenza A virus (26 resembling A/Port Chalmers/1/73, 16 resembling A/Scotland/840/74, 19 untyped, of which 16 were diagnosed by immunofluorescence only) and 124 (28 %) with RSV. (docksci.com)
According to the study, these findings suggest that nirsevimab, palivizumab, and motavizumab are effective in preventing respiratory syncytial virus infection and related hospitalizations without increasing the risk of adverse events in infants and children at high risk for RSV infection. (consultantlive.com)
Appropriately timed diagnostic tests can provide data that indicate when the RSV season begins nationally and regionally, information that has been critical in determining when to begin RSV prophylaxis for infants and children at high risk for infection. (cdc.gov)
RSV (respiratory syncytial virus) is a virus that can lead to a respiratory infection in babies, children and adults of all ages. (clevelandclinic.org)
Tens of thousands of young children are hospitalized every year with severe respiratory syncytial virus infection. (sharecare.com)
Results: Respiratory syncytial virus (RSV) is the most common viral bronchiolitis in young children. (benthamscience.com)
This vaccine is generally only given to children under the age of five, as adults are less likely to get a Hib infection. (healthline.com)
Symptoms are also typically exacerbated by viral upper respiratory infections, and these viral symptoms can linger for weeks in children with asthma, whereas age-controlled counterparts tend to recover much sooner. (medicinenet.com)
In an asthma exacerbation, the respiratory rate increases, the heart rate increases, and children can look as if breathing is much more difficult. (medicinenet.com)

It is a biofilm-forming opportunistic pathogen causing life-threatening chronic infections in immunocompromised individuals with diseases like burn wounds, urinary tract infections, and respiratory infections ( Gellatly and Hancock, 2013 ). (frontiersin.org)

Dr. Casola is a physician-scientist specialized in pediatric infectious diseases, with research expertise in the area of respiratory viral pathogens, lung inflammation, and cellular signaling. (utmb.edu)
MicroDose's current pipeline targets respiratory diseases such as asthma, COPD and RSV, as well as IBS-C and constipation. (gilead.com)

This includes supplemental oxygen when indicated, management of respiratory secretions and maintaining hydration. (medscape.com)
Secretions can be analyzed for virus in the laboratory by means of culture, antigen-revealing techniques, or polymerase chain reaction (PCR). (medscape.com)

The IL-beta and leukotriene C4 were not altered by RSV infection in bronchial cells. (nih.gov)
The aim of the study was to evaluate early RSV infection as a risk factor for asthma, bronchial reactivity, and lung function abnormalities in young adults. (nih.gov)
However, RSV infection in infancy was not a significant risk factor for asthma or bronchial reactivity. (nih.gov)

This response like the acute CTL response was found to be restricted to the lower respiratory tract. (microbiologyresearch.org)
The desired vaccine would prevent lower respiratory infection from RSV in at-risk populations and if possible, be useful in other populations with less risk. (wikipedia.org)
To compare patient management in Europe, the United States, and Australia, we analyzed the charts of 1,563 pediatric patients hospitalized with laboratory-confirmed RSV lower respiratory infections during recent RSV seasons. (nih.gov)

GSK -3888550A is under clinical development by GSK and currently in Phase III for Respiratory Syncytial Virus (RSV) Infections. (pharmaceutical-technology.com)
Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. (cdc.gov)
The search utilized keywords and vocabulary related to monoclonal antibodies, respiratory syncytial virus, and randomized clinical trials to ensure all relevant studies were considered. (consultantlive.com)

It's caused by a virus - often respiratory syncytial virus (RSV) or rhinovirus. (kidshealth.org.nz)
Other viruses such as human rhinovirus and coronavirus could be etiological agents. (benthamscience.com)
Probable or confirmed ongoing case of viral respiratory infection (including COVID-19, influenza, rhinovirus, etc.) at the time of enrollment. (who.int)

Dual infections with bacteria and viruses are associated with high mortality. (who.int)
Pseudomonas aeruginosa is a biofilm-forming opportunistic pathogen which causes chronic infections in immunocompromised patients and leads to high mortality rate. (frontiersin.org)

These illnesses typically begin with upper respiratory symptoms and fever, then progress over several days to dyspnea, cough, wheezing, and/or crackles on chest auscultation. (msdmanuals.com)
Difficulty breathing, severe muscle or chest pain, and worsening fever or cough are some possible signs of a severe flu infection that may require emergency medical care. (healthline.com)

The American Academy of Pediatrics has released updated guidelines addressing palivizumab prophylaxis for respiratory syncytial virus (RSV). (medscape.com)

Pulmonary A2 strain respiratory syncytial virus infection of BALB/c laboratory mice persisted for up to 7 days after initial infection with peak virus titres being recovered on day 4. (microbiologyresearch.org)
An association between MMP-9 and impaired T cell migration in ethanol-fed BALB/c mice infected with respiratory syncytial virus-2A. (cdc.gov)
BALB/c mice were randomly selected to consume 18% alcohol ad libitum for 8 weeks prior to infection with RSV-2A. (cdc.gov)

Does prefusion F protein-based respiratory syncytial virus immunization in pregnancy safely promote transplacental transfer of neutralizing antibodies? (nature.com)

In adults, RSV infection is typically mild, but may lead to severe outcomes. (gsk.com)

Perez-Yarza EG, Moreno A, Lazaro P, Mejias A, Ramilo O. The association between respiratory syncytial virus infection and the development of childhood asthma: a systematic review of the literature. (medscape.com)
Epidemiological data suggest that respiratory syncytial virus (RSV) infection in early life is a risk factor for later asthma. (nih.gov)
A typical history is a child with a family history of asthma and allergies who experiences coughing and difficulty breathing when playing with friends and/or who experiences frequent bouts of bronchitis or prolonged respiratory infections. (medicinenet.com)

They can also distinguish between the different types of influenza viruses, including influenza A and B, and their different season subtypes. (healthline.com)

Croup is a respiratory condition caused by an acute viral infection. (healthline.com)

There is a small chance of your child becoming sicker if the infection spreads - if this happens you should take your child to your family doctor. (kidshealth.org.nz)

Traditionally, antibody-mediated protection against viral infections is thought to be mediated by direct binding of antibodies to viral particles, resulting in virus neutralization. (ru.nl)
Her research is focused on the investigation of viral- and host-specific mechanisms that contribute to the pathogenesis of respiratory viral infections. (utmb.edu)

To describe an in vitro model of human respiratory epithelium in primary cell culture linked with a computer microscope interface that allows evaluation and imaging of living RSV-infected respiratory epithelium. (nih.gov)
Influenza virus was isolated in monkey kidney or human embryo kidney cells, and RSV in bovine testis (Caul, Jacobs & Clarke, 1974), HEp-2, HeLa, or monkey kidney cells. (docksci.com)
To download a certificate of analysis for Human respiratory syncytial virus ( VR-1803 ), enter the lot number exactly as it appears on your product label or packing slip. (atcc.org)
The certificate of analysis for that lot of Human respiratory syncytial virus ( VR-1803 ) is not currently available online. (atcc.org)

Respiratory syncytial virus (RSV) infections typically overlap with flu season, occurring in the late fall and winter. (blackdoctor.org)

A lab test of nasal fluid or another respiratory specimen to check for RSV. (medlineplus.gov)
In that case, they identify the virus by testing nasal fluids. (kidshealth.org)

Anatomy24

Organisms54

Diseases30

Chemicals and Drugs46

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Phenomena and Processes36

Disciplines and Occupations2

Information Science4

Named Groups3

Health Care10

Geographicals1

Pneumonia16

Vaccines6

20235

Centers for Diseas3

Disease28

Cases of respiratory syncy2

Hospitalization10

Epidemiology3

Among Infants3

Illness14

Infants and young children1

Older adults2

Virology1

Vaccine candidate1

Complications2

Immune7

Prevention4

Common respiratory2

Maternal3

Vaccination3

Bacterial3

Symptoms of respiratory2

Surveillance8

Highly contagious3

Antiviral6

Abstract2

Droplets3

Burden1

High-risk infants1

Hospitalized with acute1

Humans2

Antibody responses1

Severe RSV infection2

Lungs5

Epithelial3

Children19

Tract infections1

Diseases2

Secretions2

Bronchial3

Lower3

Clinical3

Rhinovirus3

Mortality2

Cough2

Pediatrics1

BALB3

Immunization1

Mild1

Asthma3

Influenza viruses1

Acute viral infection1

Spreads1

Viral infections2

Human4

Typically1

Nasal2