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  • pathogens
  • The data presented in these studies raised the intriguing possibility that methanogens possess important immunomodulatory functions that could impact clinical outcomes following infection with enteric pathogens" says Dr. Sztein. (umaryland.edu)
  • Typhoid fever is still common in the developing world, where it affects about 21.5 million persons each year.Besides being a first step towards a possible oral paratyphoid A vaccine for the prevention of enteric fever, this Phase 1 trial will shed light on the suitability of the guaBA,clpX strategy for attenuating non-typhoidal Salmonella, also an emerging pathogens of public health importance. (clinicaltrials.gov)
  • Infections with protozoal pathogens are slower to manifest symptoms and collectively account for approximately 10% of diagnoses in longer-term travelers. (cdc.gov)
  • Typhoid remains a deadly disease in many developing countries and, as the article by Lynch et al clearly demonstrates, has the potential for worldwide spread, with considerable effects on the global burden of infection with gastrointestinal pathogens. (medindia.net)
  • hepatitis
  • All travelers to India should be up-to-date with their routine immunizations and are advised to consider hepatitis B vaccine. (cdc.gov)
  • Hepatitis A vaccine is available that is 95% effective in preventing the disease. (medindia.net)
  • A combined Typhoid Fever and Hepatitis A vaccine is also available in Canada and Europe. (iamat.org)
  • In Japan, an estimated 400,000 people are infected with the hepatitis B virus (HBV), a viral hepatitis that is one of the most widespread infections in the country, mainly as the result of group vaccinations. (biomedcentral.com)
  • endemic areas
  • In addition, the authors report that "identification of nalidixic acid-resistant S Typhi (NARST) and reports of infection with S Typhi strains resistant to ciprofloxacin from typhoid-endemic areas have generated concern that strains resistant to fluroquinolones may become more prevalent. (medindia.net)
  • infectious
  • Clinical manifestations of acute infectious encephalitis can be highly variable, even among patients afflicted by the same organism, and depend on the severity of infection, anatomic sites involved, and host factors such as immune response. (neurologyadvisor.com)
  • Yet another infectious disease staging a big comeback in the West seems to be typhoid. (medindia.net)
  • Salmonella Infections
  • Salmonella has been a model pathogen for examining CD4 T cell activation and effector functions for many years due to the strength of the Th1 cell response observed during Salmonella infections, the relative ease of use of Salmonella , the availability of Salmonella -specific T cell reagents, and the well-characterized nature of the model system, the pathogen, and the immune response elicited. (frontiersin.org)
  • strains
  • If a protein based vaccine could be produced that can protect against all strains of the pneumococcus, this would be of tremendous value and our discovery that NLRP3 is needed for protection will point us in the right direction in terms of how to develop such vaccines. (medindia.net)
  • The study also shows an increase in certain strains of typhoid fever that are resistant to the most commonly used medications for treatment. (medindia.net)
  • strain
  • A study in the August 26 issue of JAMA has revealed that infection with an antimicrobial-resistant strain of typhoid fever among patients in the United States is associated with international travel, especially to the Indian subcontinent. (medindia.net)
  • A milder strain of the disease, called paratyphoid and which cannot be vaccinated against, increased by 78% over the last five years. (medindia.net)
  • Streptococcus
  • The discovery will lead to a dramatic shift in our understanding of how the body's immune system responds to infection caused by Streptococcus pneumoniae and pave the way for more effective vaccines. (medindia.net)