Infection with dengue. Medical search. Frequent questions

In a small proportion of cases, the virus causes increased vascular permeability that leads to a bleeding diathesis or disseminated intravascular coagulation (DIC) known as dengue hemorrhagic fever (DHF). (medscape.com)
The WHO estimates that 50-100 million cases of dengue infection occur annually, with approximately 500,000 of those cases resulting in dengue hemorrhagic fever (DHF), with an estimated 22,000 deaths per year, mostly in children. (medscape.com)
On November 25, 1994, the Ministry of Health of Nicaragua announced the isolation of dengue type 3 (DEN-3) from two children hospitalized with minor hemorrhagic manifestations in Managua. (cdc.gov)
Genetic typing of the initial DEN-3 isolate from Panama at CDC indicated the virus belongs to the Sri Lanka/India genotype, which caused major dengue hemorrhagic fever (DHF) epidemics in Sri Lanka and India during 1989-1992. (cdc.gov)
Reviews of medical records at two hospitals indicated that 35 (5.2%) of 676 hospitalized patients met the diagnostic criteria for dengue hemorrhagic fever (DHF). (cdc.gov)
however, a new model using high doses of DENV has recently been shown to develop hemorrhagic signs after infection. (mdpi.com)
Subsequent infections by other serotypes also increase the risk of developing severe, or hemorrhagic, dengue. (pasteur.fr)
A severe form of dengue fever, (dengue hemorrhagic fever) can cause severe bleeding, a sudden drop in blood pressure and death. (merck.com)
However, without effective treatment and a safe licensed vaccine, dengue infection can lead to debilitating illnesses, including severe pain and hemorrhagic fever. (uvm.edu)
Dengue virus (DV) is a mosquito-borne flavivirus that causes hemorrhagic fever in humans. (unboundmedicine.com)
Hemostatic defects in dengue hemorrhagic fever. (microbiologyresearch.org)
Treatment of dengue focuses on relieving symptoms and, for dengue hemorrhagic fever, fluids and blood products given intravenously. (msdmanuals.com)
Recently, Sri Lanka has experienced a string of widespread dengue epidemics annually which has now become a hyperendemic with frequent reports of dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) [ 3 ]. (biomedcentral.com)
Dengue Hemorrhagic Fever 10 cases and 32 cases of Dengue Fever. (unair.ac.id)
Until now spectrum of clinical illness dengue virus infection from an asymptomatic or mild febrile illness to classical dengue fever (DF) and then to the most severe illness for example dengue hemorrhagic fever (DHF) are always found in Indonesia town. (unair.ac.id)
CONCLUSIONS: To prevent the outbreak of dengue hemorrhagic fever the Health Center doctor should give health education to community for decreasing Aedes aegeypti Mosquito around their houses. (unair.ac.id)
In a small proportion of cases, the disease develops into a more severe dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where dangerously low blood pressure occurs. (wikipedia.org)
Dengue and other viral hemorrhagic fevers in India. (rjptonline.org)
11. Kurane I. Dengue hemorrhagic fever with special emphasis on immunopathogenesis. (rjptonline.org)

Dengue vaccine was approved by the FDA in 2019 for prevention of dengue disease caused by dengue virus serotypes 1, 2, 3, and 4 in individuals aged 9-16 years with laboratory-confirmed previous dengue infection who live in endemic areas. (medscape.com)
During this period, all dengue activity in the Americas was associated with dengue serotypes 1, 2, and 4 (DEN-1, DEN-2, and DEN-4). (cdc.gov)
The two arrived at the very beginning of what would become a massive epidemic of dengue virus Type 2, one of the more severe of the four flavors, or serotypes, of dengue, and the first major outbreak of dengue since the Zika epidemic in 2016. (sciencedaily.com)
There are four distinct serotypes of the dengue virus: DEN-1, DEN-2, DEN-3 and DEN-4. (pasteur.fr)
It is therefore possible to be re-infected by other dengue serotypes. (pasteur.fr)
The one commercially available vaccine is only partly effective against infection by the four serotypes of the virus, although it does reduce the risk of developing the severe form of the disease. (pasteur.fr)
The findings of this original study open up new avenues of research for the development of a vaccine against the dengue virus that will offer more comprehensive protective immunity against the four serotypes of the dengue virus and also prevent the spread of this disease, which represents a considerable global threat. (pasteur.fr)
One of the challenges of dengue infection is that it can be caused by one of four versions - or serotypes - of the virus, which are numbered dengue 1 to 4. (uvm.edu)
Over a six-month period, Diehl and his colleagues tracked the immune response and measured its different aspects, from the levels of certain immune blood cells to the levels of antibodies they produce and how these antibodies can recognize different dengue serotypes. (uvm.edu)
Colombia is an endemic country for dengue fever where the four serotypes of virus dengue (DENV1-4) circulate simultaneously, and all types are responsible for dengue cases in the country. (mdpi.com)
According to Dr. Kelli L. Barr, author of Dengue Serotypes 1-4 Exhibit Unique Host Specificity In Vitro, 'The central message of our work is that if some dengue viruses grow well in various animal tissues (cell lines) then perhaps animals play a bigger role than we now believe in the preservation and spread of dengue viruses. (dovepress.com)
Our data support other reports that show that bats may serve as hosts for dengue virus and that dengue serotypes exploit unique cell entry pathways. (dovepress.com)
Infection with one of the serotypes protects against infection with that serotype for a long time but provides only limited and temporary protection against infection with the other serotypes. (msdmanuals.com)
Two kinds of vaccines were invented while four distinct serotypes of the dengue virus exist, with numerous virus strains found worldwide. (tbsnews.net)
However, subsequent dengue infections by other serotypes may carry high risk of developing severe dengue, dengue haemorrhagic fever or dengue shock syndrome , which can be life-threatening. (thomsonspecialists.com)
The U.S. Food and Drug Administration announced today the approval of Dengvaxia, the first vaccine approved for the prevention of dengue disease caused by all dengue virus serotypes (1, 2, 3 and 4) in people ages 9 through 16 who have laboratory-confirmed previous dengue infection and who live in endemic areas. (news-medical.net)
The dengue virus is categorised into four varieties based on 'serotypes'-structures present on the surface of the virus. (researchmatters.in)

Persons not previously infected are at an increased risk of severe dengue disease when vaccinated and subsequently infected with dengue virus. (medscape.com)
Women who have previously been infected with dengue virus may be at risk for increased damage to their fetuses and placentas if they should later become infected with the Zika virus, researchers from the Department of Microbiology at the Icahn School of Medicine at Mount Sinai report. (infectioncontroltoday.com)
Dr Paulo Rocha from the University of Bath's Department of Electronic & Electrical Engineering is developing a low-cost integrative sensing tool for early detection of Dengue virus, using a novel platform containing electrical sensors to investigate the behavior of human cells infected with Dengue virus. (news-medical.net)
Typically, people infected with dengue virus are asymptomatic (80%) or have only mild symptoms such as an uncomplicated fever. (wikipedia.org)

With endemic transmission in Asia and the Americas, recent outbreaks in Portugal, the ever-increasing incidence in Africa, and the challenges of making an effective dengue vaccine or controlling the vector, Professor Farrar stresses: 'This really does represent a crucial period in the global spread of dengue. (ox.ac.uk)
Professor Farrar states: "This really does represent a crucial period in the global spread of dengue. (planetsave.com)
The increase in temperature is the main reason for the spread of dengue infection in the mountains. (gavi.org)

On November 7, 2022, dengue virus (DENV), which is not endemic in the continental United States, [ 1 ] was identified in a Maricopa County, Arizona resident by reverse transcription-polymerase chain reaction (RT-PCR) testing at Arizona State Public Health Laboratory (ASPHL). (medscape.com)
Whole genome sequencing by CDC's Dengue Branch later revealed that closely related DENV-3 strains not known to be circulating in the patient's travel region were identified in both patient A and pool A, suggesting local DENV transmission. (medscape.com)
Dengue is caused by infection with any of four mosquito-transmitted dengue viruses (DENV-1-4) and is characterized by fever, headache, myalgia, and leukopenia ( 1 ). (cdc.gov)
This report describes a fatal case of acquired HLH that was apparently triggered by infection with DENV-3. (cdc.gov)
The development of animal models of dengue virus (DENV) infection and disease has been challenging, as epidemic DENV does not naturally infect non-human species. (mdpi.com)
In contrast, certain immunodeficient mouse models infected with mouse-adapted DENV strains show signs of severe disease similar to the 'vascular-leak' syndrome seen in severe dengue in humans. (mdpi.com)
DENV are major re-emerging pathogens that are endemic in all continents except Europe and Antarctica with over half of the world's population at risk of infection. (dovepress.com)
DENV is the most common human arboviral infection and the most important public health threat. (dovepress.com)
These findings provide a new foundation upon which our understanding of DENV infection and evolution may be built, and may provide new insights for treatment of this terrible disease,' explains Dr. Jonathan Dinman, editor-in-cheif, Virus Adaptation and Treatment journal. (dovepress.com)
Emerging viruses, such as dengue (DENV) and Ebola (EBOV), pose threats to military and global health. (dtic.mil)
Vertical transmission in Aedes aegypti and Aedes albopictus is considered a maintenance mechanism for dengue virus (DENV) during unfavorable conditions and may be implicated in dengue outbreaks. (nature.com)
Since DENV infection dynamics vary among wild-type viruses and vector populations, vertical transmission rates can also vary between regions. (nature.com)
Dengue virus (DENV) is the most geographically widespread arbovirus causing dengue disease epidemics in tropical and subtropical regions. (ugm.ac.id)
Nature provides abundant plants as a source for lead molecules against various diseases including DENV infection. (ugm.ac.id)
In conclusion, curcumin and 6‐gingerol exhibit antiviral properties against DENV infection and could provide a new therapeutic approach for dengue disease treatment strategies. (ugm.ac.id)
The dengue virus (DENV), which infects humans through the bite of infected mosquitoes, is the root cause of the dengue viral infection. (newsmakhani.com)
While many DENV infections are asymptomatic or only cause mild illness, high fever, headache, body aches, nausea, and rash, DENV can sporadically cause more severe cases and even death. (newsmakhani.com)
Dengue Virus (DENV) is transmitted by mosquito bite. (rjptonline.org)
We conclude that DENV-1-LVHC was well-tolerated, resulted in an uncomplicated dengue illness, and may be a suitable DHIM for therapeutic and prophylactic product testing. (nih.gov)

In October and November, as the result of increased dengue transmission in Managua, the Ministry of Health initiated a multifaceted response to control Aedes aegypti, the mosquito vector of dengue. (cdc.gov)
The dengue virus is similar to the Zika virus - they belong to the same viral family, called the Flaviviridae, and both are transmitted by the Aedes mosquito. (imperial.ac.uk)
Dengue is a viral disease transmitted to humans by mosquitoes of the Aedes genus. (pasteur.fr)
Dengue, which is spread by Aedes mosquitoes, has traditionally been considered a bug of lower-lying and tropical climates. (gavi.org)
Background: The mosquito Aedes aegypti was recently transinfected with a life-shortening strain of the endosymbiont Wolbachia pipientis (wMelPop) as the first step in developing a biocontrol strategy for dengue virus transmission. (psu.edu)
Get rid of breeding places: Standing water is a breeding ground for the Aedes mosquitoes that spread dengue. (newsmakhani.com)
According to the WHO, dengue is a viral infection caused by the bite of mosquitoes of the Aedes aegypti that happens when tropical and subtropical climates arrive in urban and semi-urban areas. (mongersmint.com)
Dengue fever is a disease caused by the dengue virus, which is transmitted by female mosquitoes mainly of the species Aedes aegypti . (thomsonspecialists.com)
Dengue is a viral disease that gets transmitted through the bite of a female Aedes mosquito. (researchmatters.in)
Dengue is spread by several species of female mosquitoes of the Aedes genus, principally Aedes aegypti. (wikipedia.org)
The Aedes mosquito - potentially together with flaviviruses like dengue and Zika - is found in most tropical and subtropical countries, and South-East Asia is no exception. (medindia.net)

Dengue, also known as 'breakbone fever', is a viral infection that is transmitted between humans by mosquitoes. (ox.ac.uk)
There are currently no licensed vaccines or specific treatments for dengue, and substantial efforts to control the mosquitoes that transmit the disease have not stopped its rapid emergence and global spread. (ox.ac.uk)
Dengue (aka break-bone fever) is a viral infection that spreads from mosquitoes to people. (allafrica.com)
Dengue, alternately known as 'breakbone fever', is a sometimes fatal viral infection that is transmitted to humans via mosquitoes. (planetsave.com)
Dr Chuman Lal Das, Director of the EDCD, says, "Diseases that occur in low-altitude areas like dengue have now started to be found in hilly and mountainous districts as the habitat of mosquitoes has shifted to higher altitudes. (gavi.org)
When mosquitoes make a home in the mountains, dengue isn't the only threat they bring with them. (gavi.org)
The infection is caused by a flavivirus that is spread by mosquitoes. (msdmanuals.com)
Individual infected mosquitoes may bite more than one person, putting multiple people at risk of infection. (msdmanuals.com)
Researchers have found a way to reduce the blood thirst of mosquitoes and prevent mosquito bites and spread of mosquito borne illnesses such as Zika, dengue fever, malaria and chikungunya. (news-medical.net)
As dengue virus is transmitted by mosquito, the CDCP performed an epidemiologic investigation and checked traces of mosquitoes within a 2 kilometer radius in the patient's neighborhood. (blogspot.com)
Dengue also has significant social and economic costs for the country as it needs management of mosquitoes, preventive measures, awareness campaigns and treatment facilities at all Primary Health Centres and other government-run healthcare provisions. (researchmatters.in)

Patients with suspected dengue infection who are maintaining adequate hydration orally and have no warning signs/symptoms may be treated on an outpatient basis with appropriate anticipatory guidance and outpatient follow-up within 24 hours for reassessment. (medscape.com)
On October 22, 1994, a 5-year-old boy was hospitalized in Managua with symptoms of classic dengue fever (i.e., fever, vomiting, and rash). (cdc.gov)
DEN-3 virus also was isolated from blood samples of two patients with symptoms of dengue fever in Panama by the Gorgas Memorial Laboratory in Panama City. (cdc.gov)
Getting sick with the mosquito-borne Zika virus makes people more vulnerable to developing dengue disease later on, and to suffering from more severe symptoms when they do get sick from dengue, finds a new study published online today (Thursday, Aug. 27) in the journal Science . (sciencedaily.com)
Dengue disease is caused by not one but four closely related types of flaviviruses, each of which can strike with a slightly different set of symptoms and severity. (sciencedaily.com)
Most people who get dengue won't have symptoms. (allafrica.com)
The increased risk of developing severe symptoms with secondary infection has been associated with the presence of non-neutralizing antibodies, which are thought to exacerbate the infection rather than preventing it. (pasteur.fr)
By looking at infected but asymptomatic patients, this study can help us understand the mechanisms that prevent the development of symptoms following infection. (pasteur.fr)
Unfortunately for the many millions of people diagnosed with sub-severe dengue fever each year, Khatri's painful symptoms are typical enough. (gavi.org)
Dengue causes flu-like symptoms that most people recover from, but also can rapidly lead to internal bleeding, organ failure and even death. (texomashomepage.com)
Symptoms of dengue typically begin about 3 to 15 days after being bitten by an infected mosquito. (msdmanuals.com)
In a recent case study from Dr. D. Y. Patil Medical College, Hospital & Research Centre in Pune, India, a 25-year-old male developed mania and psychotic symptoms following a dengue fever infection. (thaimedicalnews.com)
As with Covid-19, dengue symptoms do not appear instantly. (mongersmint.com)
Symptoms typically begin three to fourteen days after infection. (news-medical.net)
Although the symptoms of dengue are treatable if detected early on, it can be potentially fatal and hence needs a better understanding to devise management strategies. (researchmatters.in)
Therefore, travelers returning from endemic areas are unlikely to have dengue fever if symptoms start more than 14 days after arriving home. (wikipedia.org)
The characteristic symptoms of dengue are sudden-onset fever, headache (typically located behind the eyes), muscle and joint pains, and a rash. (wikipedia.org)
Even when they do get sick, the symptoms can easily be confused with other diseases such as the flu or dengue. (medindia.net)

The study, which drew on data from two cohorts of Nicaraguan children who lived through a Zika epidemic in 2016 and a dengue epidemic in 2019, is the first to investigate the impacts of Zika immunity on dengue disease in humans. (sciencedaily.com)
Using data from the cohort, Harris published a 2019 study showing that prior dengue virus infection can grant a small amount of protection against Zika, and other studies now support this conclusion. (sciencedaily.com)
This is a decline of around 86% and for 2020, there were no dengue-related deaths recorded compared to 10 for 2019. (guardian.bz)
In 2019, 17,992 dengue cases were reported in 68 districts. (gavi.org)

A new study finds that people who have antibodies to the mosquito-borne Zika virus are more vulnerable to developing dengue disease. (sciencedaily.com)
Its findings confirm earlier suspicions that some antibodies to the Zika virus, which usually serve to protect the body from infection, may actually interact with dengue viruses in ways that can make dengue infection worse. (sciencedaily.com)
because everyone in Latin America, to some degree or another, is eventually dengue immune and has dengue antibodies," said study senior author Eva Harris, a professor of infectious diseases and vaccinology at UC Berkeley. (sciencedaily.com)
Since 2004, Harris and her colleagues in Nicaragua have monitored a cohort of approximately 3,800 children living in Managua, the country's capital, tracking any signs of dengue disease and collecting annual blood samples to test for the virus and its antibodies. (sciencedaily.com)
But the inverse question, whether Zika antibodies protect against future dengue disease, or potentially enhance it, remained a mystery. (sciencedaily.com)
In the new Nature Immunology paper, supported by the Wellcome Trust and the Medical Research Council , the researchers used antibodies that recognise the dengue virus collected from individuals who had been infected with dengue. (imperial.ac.uk)
Their results suggest dengue antibodies can recognise and bind to Zika, due to the similarities between the viruses. (imperial.ac.uk)
Crucially, they also suggest that pre-existing dengue antibodies can amplify a Zika infection through a phenomenon called antibody-dependent enhancement (ADE). (imperial.ac.uk)
When dengue first infects the body, the immune system makes antibodies against the virus. (imperial.ac.uk)
If someone is infected a second time by a different strain, the antibodies from the first attack can only partially bind to the virus, and are unable to prevent infection. (imperial.ac.uk)
The existing dengue antibodies latch onto Zika, due to similarity between the viruses. (imperial.ac.uk)
Previous work from the team has shown the immune system generates different types of antibodies to dengue that bind to various areas of the virus. (imperial.ac.uk)
In the current study, the team found a group of antibodies that bind to a certain site on the dengue virus - called EDE1 antibodies - were able to prevent the Zika virus from entering the immune cell. (imperial.ac.uk)
In a second study, published in Nature and co-authored by Professor Felix Rey from the Institut Pasteur and Professor Screaton from Imperial, the team confirmed that EDE1 antibodies bind efficiently to the Zika virus and potently neutralise infection. (imperial.ac.uk)
Experts believe this phenomenon occurs due to a part of the immune response, the antibodies, which may recognize and promote the second infection rather than defeat it. (uvm.edu)
With a comprehensive approach, the study dissected the antibody response at the single-cell level resolution, mapped the interaction between human antibodies to structural components on the virus's surface, and connected the functional features of the response during acute infection to time points past recovery. (uvm.edu)
The research team led by Jean Lim, PhD, associate professor of microbiology and co-director of microbiology multidisciplinary training in the Graduate School of Biomedical Sciences at the Icahn School of Medicine at Mount Sinai, transferred dengue virus-specific antibodies into mice prior to infection with Zika virus during pregnancy. (infectioncontroltoday.com)
Zika-infected human placental tissues also showed increased replication in the presence of dengue antibodies. (infectioncontroltoday.com)
Our data demonstrate that antibodies generated from a previous dengue virus infection can enhance the severity of Zika virus infection during pregnancy,' said Dr. Lim. (infectioncontroltoday.com)
A panel of 11 murine monoclonal antibodies directed against dengue type 2 was evaluated for antigen specificity by dot immunobinding assay and Western blot analysis and for in vitro and in vivo biological activities. (ajtmh.org)
The nine E-glycoprotein-reactive monoclonal antibodies also neutralized dengue 2 virus in a plaque reduction assay. (ajtmh.org)
Of the neutralizing monoclonal antibodies, five passively protected mice in vivo against lethal intracerebral dengue 2 challenge. (ajtmh.org)
Infection enhancement of dengue type 2 virus in the human U-937 monocyte line by antibodies to Flavivirus cross-reactive determinants. (microbiologyresearch.org)
To diagnose dengue, doctors do blood tests to check for the virus or antibodies to the virus. (msdmanuals.com)
1 blood sam ple was taken and sent to lab for detection of dengue spe cific antibodies, result for IgM was found positive. (who.int)

Take 5 minutes to catch up on Infection Control Today®'s highlights for the week ending December 10, 2023. (infectioncontroltoday.com)
A man attends to his wife who is being treated for dengue at Mugda Medical College and Hospital in Dhaka, Bangladesh, Thursday, Aug. 10, 2023. (texomashomepage.com)

KENILWORTH, N.J.-( BUSINESS WIRE )-Merck (NYSE:MRK), known as MSD outside the United States and Canada, and Instituto Butantan, Sao Paulo, Brazil, a non-profit producer of immunobiologic products for Brazil today announced a collaboration agreement to develop vaccines to protect against dengue virus disease, the mosquito-borne infection. (merck.com)
Dengue fever is a mosquito-borne disease that occurs in tropical and subtropical areas of the world. (merck.com)
Study findings, reported recently in the Lancet 's open-access journal EBioMedicine , illustrate new critical information that could provide much-needed help to evaluating dengue vaccine formulations and assist with advancing safe and efficacious candidate vaccines to help combat the most important mosquito-borne viral infection in our time. (uvm.edu)
Like Zika, yellow fever and West Nile viruses, dengue belongs to a group of mosquito-borne viruses that circulate in many tropical countries. (uvm.edu)
The infection and death rate will further decline if people become more aware of the mosquito-borne disease and maintain health guidelines properly," the health minister said while talking to journalists at his residence in Chandair village of Manikganj Sadar upazila this afternoon, reports the BSS. (tbsnews.net)
Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. (news-medical.net)
Dengue, a mosquito-borne illness, wreaks enough havoc to get attention from the press every year. (researchmatters.in)

abstract = "BACKGROUND: Since 1968 dengue virus infection has been found in several cities in Indonesia, especially Surabaya and Jakarta, this event occurs due to the changing of the hot weather to rainy season. (unair.ac.id)

The global burden of dengue infection is more than triple current estimates from the World Health Organization, according to a multinational study published in the journal Nature . (ox.ac.uk)
2013. The global distribution and burden of dengue. (ugm.ac.id)
Researchers have now conducted an analysis of the economic burden of dengue fever in Burkina Faso, Kenya and Cambodia. (news-medical.net)

This immune interaction, called antibody-dependent enhancement, could complicate the search for a safe and effective vaccine that protects against Zika without also increasing the risk of dengue. (sciencedaily.com)
This interaction, known as antibody-dependent enhancement, could make it harder for researchers to design a safe and effective vaccine that protects against Zika without also increasing the risk of dengue. (sciencedaily.com)
The key thing that our study establishes is that prior Zika infection does significantly increase your risk of both symptomatic and more severe forms of dengue disease," said study first author Leah Katzelnick, who performed the research as postdoctoral scholar at the University of California, Berkeley's School of Public Health. (sciencedaily.com)
That finding raises the questions: Could a vaccine only targeted at Zika actually put people at increased risk of more severe dengue disease? (sciencedaily.com)
When Zika first emerged in Latin America in late 2015, many speculated whether the flavivirus, a close cousin to the dengue viruses, might interact with the dengue viruses in a similar way. (sciencedaily.com)
The first question was, 'How will prior dengue virus infection affect Zika? (sciencedaily.com)
I wonder if previous infection with Zika is pushing people into symptomatic disease? (sciencedaily.com)
By mid-autumn, the researchers had enough evidence to prove that having a prior Zika infection made a person more likely to have a symptomatic dengue infection. (sciencedaily.com)
Previous exposure to the dengue virus may increase the potency of Zika infection, according to research from Imperial College London. (imperial.ac.uk)
The early-stage laboratory findings, published in the journal Nature Immunology , suggests the recent explosive outbreak of Zika may have been driven in part by previous exposure to the dengue virus. (imperial.ac.uk)
Professor Gavin Screaton , senior author of the research and Dean of the Faculty of Medicine at Imperial, said: "Although this work is at a very early stage, it suggests previous exposure to dengue virus may enhance Zika infection. (imperial.ac.uk)
A second study by the same team, published in Nature , suggests an antibody that works against the dengue virus may also neutralise Zika - providing a potential target for a vaccine. (imperial.ac.uk)
The new study suggests the same phenomenon occurs when a person who has previously been exposed to dengue encounters Zika. (imperial.ac.uk)
Investigators in UVM's Vaccine Testing Center and Center for Translational Global Infectious Disease Research (TGIR) have uncovered details of the human immune response to infection with dengue - a close "cousin" of the Zika virus - which 40 percent of the global population is at risk for contracting. (uvm.edu)
Results of the study, 'Dengue virus immunity increases Zika virus-induced damage during pregnancy,' were published in the February issue of Immunity, a journal published by Cell Press. (infectioncontroltoday.com)
Zika virus outbreaks were first found to be associated with birth defects including microcephaly, in which the baby is born with an abnormally small head and brain, in 2015 in Brazil, where dengue virus, a virus closely related to Zika virus, is endemic. (infectioncontroltoday.com)
Researchers at QUT and QIMR Berghofer Medical Research Institute have found that the dengue fever mosquito common to north and central Queensland poses the greatest danger of spreading the Zika virus in Australia. (news-medical.net)
Dengue and Zika virus infection has been found to up against a human and mosquito immune defense mechanism and highjack specific host proteins for virus replication. (medindia.net)

Diagnostic testing was negative for infection with hepatitis A, B, and C viruses. (cdc.gov)
However, after a person has been infected with two types of dengue viruses, they usually gain some degree of immune protection against future dengue disease severity. (sciencedaily.com)
Perhaps there is much more to learn about dengue viruses and wild and domestic animal hosts. (dovepress.com)
Replication of dengue and Junin viruses in cultured rabbit and human endothelial cells. (microbiologyresearch.org)
Overview of Arbovirus, Arenavirus, and Filovirus Infections Arbovirus, arenavirus, and filovirus are viruses that are spread from animals to people and, with some viruses, from people to people. (msdmanuals.com)
2013. Performance of commercial dengue NS1 ELISA and molecular analysis of NS1 gene of dengue viruses obtained during surveillance in Indonesia. (ugm.ac.id)
Occurrence of co-infection with dengue viruses during 2014 in New Delhi, India. (bvsalud.org)
Evolutionary relationships of endemic/epidemic and sylvatic dengue viruses. (rjptonline.org)
My group apply the techniques of elecrton-cryomicroscopy and image analysis to the study of viruses, providing an exciting opportunity to visualise the process of virus infection at cellular scale and at macromoleculr resolution. (gla.ac.uk)
Many human viruses utilise or suppress ubiquitin and ubiquitin-like pathways during infection, enhancing their replication. (gla.ac.uk)
We explore the intricate structural interactions between viruses and host complexes during virus infection and immune response, which is crucial for exploiting them and uncovering new avenues for the development of therapeutics. (gla.ac.uk)

Scientists in the Laboratory of Infectious Diseases at the NIAID of the NIH engineered a candidate live attenuated tetravalent vaccine against the dengue virus. (merck.com)

In 20-30% of DHF cases, the patient develops shock, known as the dengue shock syndrome (DSS). (medscape.com)
Increased blood vessel permeability, which occurs in dengue haemorrhagic fever and dengue shock syndrome patients, has been correlated with secondary heterotypic infections and has been postulated to arise from antibody-enhanced infection of monocytes. (microbiologyresearch.org)
Severe dengue, dengue haemorrhagic fever and dengue shock syndrome are dengue infections that become severe and potentially have fatal complications, which often require hospitalization. (thomsonspecialists.com)
There is no specific treatment for dengue fever, severe dengue, dengue haemorrhagic fever and dengue shock syndrome. (thomsonspecialists.com)

Until now, little was known about the current distribution of the risk of dengue virus infection and its public health burden around the world. (ox.ac.uk)

However, there are four different types of dengue virus. (imperial.ac.uk)

The announcement came as the Centers for Disease Control and Prevention (CDCP) conducted an investigation into a Dengue fever outbreak in South Gyeongsang Province last July to verify whether the patient was infected locally. (blogspot.com)

Infections are typically accompanied by widespread cases of malaria and diarrhoea. (allafrica.com)
And with them, the many diseases that they carry, such as malaria and dengue. (planetsave.com)
In mountainous countries including Nepal, not only dengue but also malaria, Japanese encephalitis and other vector-borne diseases have been observed in high altitudes," says Dr Meghnath Dhimal, chief of the NHRC's research section. (gavi.org)

The team estimate that there are 390 million dengue infections across the globe each year, of which 96 million reach any level of clinical or subclinical severity. (ox.ac.uk)
The World Health Organization has estimated that up to 400 million dengue infections occur annually, resulting in 500,000 hospitalizations. (merck.com)

Dengue fever is a benign, acute febrile syndrome occurring in tropical regions. (medscape.com)
In areas where both leptospirosis and dengue are endemic, both infections should be include in the differential diagnosis when evaluating patients with acute febrile illness and should consider the possibility of co-infection. (biomedcentral.com)
Role of skin homing T cells in acute dengue infection. (ox.ac.uk)
Treatment of acute dengue is supportive and includes giving fluid either by mouth or intravenously for mild or moderate disease. (wikipedia.org)
My team within the Experimental Virology Group focuses on immune mechanisms triggered by acute viral infections. (rug.nl)

Scientists from the Institut Pasteur in Paris and the Institut Pasteur in Cambodia, in collaboration with teams from the CNRS and Inria, have demonstrated that asymptomatic dengue infection in children is associated with activation of the immune system via control mechanisms, resulting in the elimination of viral infection without excessive immune activation. (pasteur.fr)
To identify the internal mechanisms used to control dengue virus infection in asymptomatic patients, scientists from the Institut Pasteur in Paris, the Institut Pasteur in Cambodia, the CNRS and Inria examined the composition of blood serum, immune cells and the gene expression profile in asymptomatic Cambodian children infected with the dengue virus and compared them to those of patients presenting with clinical signs. (pasteur.fr)

Hence, a second infection could result in severe dengue infection. (researchmatters.in)

How do I check for a previous dengue infection? (thomsonspecialists.com)

This paper, published in the scientific journal Science Translational Medicine on August 30, 2017, represents an important step in improving understanding of the role played by immunity in dengue viral infection. (pasteur.fr)
First time dengue infection is believed to provide lifelong immunity against that serotype. (thomsonspecialists.com)
This finding has implications for cases when a person gets infected by dengue for the second time, as he/she may have developed immunity for the first serotype but not for the second one. (researchmatters.in)
infection with one type usually gives lifelong immunity to that type, but only short-term immunity to the others. (wikipedia.org)
My research focuses on companion animal virology and immunology with a view to understanding disease pathogenesis, correlates of immunity to infection and the development of novel approaches to the diagnosis, prevention and treatment of viral diseases. (gla.ac.uk)

However, even though São Paulo is the most populous city in the Americas and has experienced major dengue epidemics, natural vertical transmission had never been detected in this area before. (nature.com)
Despite the fact that São Paulo, the capital of the state, is the most populous city in Brazil and Latin America 22 and in recent years has experienced major dengue epidemics, such as those in 2014 and 2015 23 , natural vertical transmission has never been detected in the city 15 . (nature.com)

Although dengue was initially found only in the world's tropical and subtropical climates, it has now reached Europe. (pasteur.fr)

An alternative name for dengue, "breakbone fever", comes from the associated muscle and joint pains. (wikipedia.org)

The role and responsibility of executive-level oversight in infection prevention is growing. (infectioncontroltoday.com)
If we work together and everybody shows awareness and acts responsibly, our collective effort will make dengue prevention possible," he said. (texomashomepage.com)
Fortunately, there are supportive therapies in Singapore and also dengue vaccine, Dengvaxia®, available for the prevention of subsequent dengue infections . (thomsonspecialists.com)
Dengue- Guidelines for Diagnosis, Treatment, Prevention and Control. (rjptonline.org)

Dengvaxia® has an efficacy of 60% in reducing dengue illness, and 84% in reducing severe dengue illness. (thomsonspecialists.com)

Getting sick with one type of dengue virus can increase the likelihood that a person will develop a second, more severe illness when infected with a separate type of dengue virus. (sciencedaily.com)

however, and in the case of dengue infections, there is actually very good news. (guardian.bz)
2. Mardani M, Abbasi F, Aghahasani M, Ghavam B. First Iranian imported case of dengue. (rjptonline.org)

Dengue has been called the most important mosquito-transmitted viral disease in terms of morbidity and mortality. (medscape.com)
Dengue is considered the most serious re-emergent viral disease transmitted by arthropods, with approximately 390 million infections worldwide each year, 7% of which occur in Brazil 1 , 2 . (nature.com)
The three new cases have brought the total number of mpox infections to 18 since the viral disease was declared to be an infectious one requiring special surveillance on May 25 of last year. (bangkokpost.com)

METHODS: Method of studied on diagnosis of dengue virus infection with using WHO criteria 2009. (unair.ac.id)
Sjahrurachman A, Ernawati B, lbrahim F, Mardiastuti M, Sudiro TM, Sudarmono P. Comparison of two dot immunoassays for diagnosis of dengue infection. (ui.ac.id)

There is no specific pharmacologic treatment for dengue infection. (medscape.com)

[ 3 ] Secondary infection by a different dengue virus serotype has been confirmed as an important risk factor for the development of DHF. (medscape.com)
It is approved only in individuals previously infected by any dengue virus serotype or in whom this information is unknown. (medscape.com)
Infection by one serotype typically results in long-term protection specific to that serotype. (uvm.edu)
Concurrent infection with more than one serotype was identified in 43% of the positive samples. (bvsalud.org)

This case underscores the need for clinicians in the United States to be vigilant for dengue and request diagnostic testing for suspected cases, which should be reported to public health authorities. (cdc.gov)
This report describes these cases and dengue activity in Nicaragua and Panama and summarizes public health activities to control dengue fever in the Americas. (cdc.gov)
El Gedaref in eastern Sudan is witnessing an increase in dengue fever* infections, with 70 confirmed cases and two deaths reported last week alone. (allafrica.com)
Similarly, the Emergency Health Department in Um Ruwaba locality in North Kordofan detained two cases of dengue fever in the isolation ward for infectious diseases after local tests confirmed that the cases were positive. (allafrica.com)
The Director General of the Ministry of Health in North Kordofan, El Fatih Nour, denied the presence of other cases of dengue fever aside from the two in Um Ruwaba. (allafrica.com)
He said that besides public places, spray should also be conducted in houses where dengue cases had occurred. (com.pk)
It causes an estimated 50 million cases of dengue infection, half a million hospitalizations, and approximately 15,000 deaths. (dovepress.com)
Classically a disease of lower-lying areas, dengue cases have this year surged in the hill zones of the Himalayan state. (gavi.org)
In 2006 - during Nepal's first dengue outbreak - 32 cases were reported. (gavi.org)
But Rawal has been alarmed to see that this year, Mugu has recorded 12 cases of dengue - an unprecedented surge for this dilutely populated, famously isolated district. (gavi.org)
In 2006 - the country's first dengue outbreak - 32 cases were noted in nine districts. (gavi.org)
In the first 10 days of August, more than 23,000 people were diagnosed with dengue, compared to 43,854 cases during all of July. (texomashomepage.com)
Infected people are overwhelming hospitals across the country, but some doctors and nurses are not sufficiently experienced, or trained, in how to treat dengue cases, experts say. (texomashomepage.com)
As of 19 February 2020, 12 pm, the Ministry of Health (MOH) has confirmed and verified three additional cases of COVID-19 infection in Singapore. (theonlinecitizen.com)
To date, a total of 34 cases have fully recovered from the infection and have been discharged from the hospital. (theonlinecitizen.com)
About 50 to 100 million cases of dengue and about 20,000 deaths occur worldwide. (msdmanuals.com)
A few cases of locally transmitted dengue have occurred in Hawaii, Florida, and Texas. (msdmanuals.com)
In Japan, although dengue cases are currently seen only among travellers returning from endemic areas, the number of reported cases is rising according to the national case-based surveillance system. (who.int)
We evaluated the characteristics of dengue cases imported into Japan and the relationship between the incidence of infection and season of travel to popular destinations. (who.int)
Dengue cases reported to the national surveillance system were retrospectively examined. (who.int)
The number of reported cases per number of Japanese travellers to a dengue-endemic country was calculated to estimate the country-specific incidence of imported dengue virus infection. (who.int)
Among 540 Japanese residents who were reported as dengue cases from 2006 to 2010, the majority had travelled to Indonesia, India, the Philippines, and Thailand. (who.int)
Overall, higher incidence of imported cases appeared to be related to historic dengue high seasons. (who.int)
The study had been done in all cases Dengue Virus Infection who had been cared in Mother and Child Health of SOERYA Hospital Sepanjang, Indonesia, since January 1/June 30, 2018. (unair.ac.id)
Focusing this study evaluation all the cases of dengue virus infection, the diagnosis of cases was based on WHO 2009. (unair.ac.id)
Beside it the hospital doctor found 22 cases were infected secondary infection of Salmonella. (unair.ac.id)
Singapore saw one of its worst dengue outbreaks in 2020 , recording 35,315 cases and 28 deaths. (thomsonspecialists.com)
As of 28 May 2022, about 11,670 dengue cases had been reported in Singapore, with 10% of cases requiring hospitalisation. (thomsonspecialists.com)
However this time the capital city Kathmandu relatively witnessed lesser number of cases mainly due to awareness and timely search and destroy of dengue larvae. (enewspolar.com)
9 suspected, 1 probable and 1 confirmed Dengue fever cases notified from Teaching Units in Lahore. (who.int)
Via The Asian Age : ' The national capital remained in the grip of dengue fever with a whopping 95 fresh cases being reported on Thurs. (blogspot.com)

Go to Dengue and Dermatologic Manifestations of Dengue for complete information on these topics. (medscape.com)
This is a significant finding as psychiatric manifestations of dengue fever have been relatively rare. (thaimedicalnews.com)

The geographic range and incidence of dengue virus activity in the Americas substantially increased from 1980 to 1994. (cdc.gov)
As the incidence of dengue fever increases, understanding its diverse clinical presentations, including psychiatric complications, is crucial for effective healthcare. (thaimedicalnews.com)
The incidence of both these diseases peaks during monsoons and both diseases present with similar clinical manifestations making differentiation of leptospirosis from dengue difficult. (biomedcentral.com)
The incidence of dengue infection among Japanese travellers was compared between dengue high season and low season in each country using relative risk (RR) and associated 95% confidence intervals (CI). (who.int)
There is a need to initiate well planned community-based cohort studies representing different geographic regions of the country to generate reliable estimates of the age-specific incidence of dengue fever in India. (researchmatters.in)

Despite 50 years of research, the pathophysiological mechanisms that lead some patients to develop a severe clinical form of dengue have not yet been clearly elucidated. (pasteur.fr)

Laboratory tests confirmed the presence of dengue fever, and the patient was treated with mood stabilizers and antipsychotic medications, which resulted in significant improvement. (thaimedicalnews.com)

India alone accounted for around one-third of all infections. (ox.ac.uk)
Dengue fever is an arthropod -borne viral infection that has become endemic in several parts of India including Delhi. (bvsalud.org)
In the current study, published in the journal PLOS Neglected Tropical Diseases , the researchers have reviewed studies published over five decades until 2017, related to dengue in India. (researchmatters.in)
The current study reports that in the year 2012 alone, the estimated medical cost for dengue in India was a staggering 548 million USD! (researchmatters.in)
A significant point made in the study is about the lack of community-based epidemiological studies on dengue in India. (researchmatters.in)
Dengue in India. (rjptonline.org)

How to prevent dengue? (mongersmint.com)

35,000) living in dengue-endemic areas. (medscape.com)
Dengue-endemic areas include the United States territories of American Samoa, Puerto Rico, and the U.S. Virgin Islands, and freely associated states, including the Federated States of Micronesia, the Republic of Marshall Islands, and the Republic of Palau. (msdmanuals.com)

In our model, we controlled the infection for safety reasons and the participants were monitored for six months in order to understand the biological changes that occur following the infection. (uvm.edu)

In 2022, 62,382 people were infected and 281 people died of dengue, according to government figures. (texomashomepage.com)

The vaccine was approximately 76% effective in preventing symptomatic VCD disease among patients aged 9-16 years who were seropositive for dengue at baseline. (medscape.com)
With globalisation and the constant march of urbanisation, we anticipate that there could be dramatic shifts in the distribution of the disease in the future: the virus may be introduced to areas that previously were not at risk, and those that are currently affected may experience increases in the number of infections. (ox.ac.uk)
The authors suggest that the hidden African dengue burden could be a result of the disease being masked by symptomatically similar illnesses, under-reporting and highly variable treatment-seeking behaviour. (ox.ac.uk)
Professor Jeremy Farrar, Director of the Wellcome Trust Vietnam Research Programme and Oxford University Clinical Research Unit Hospital for Tropical Diseases in Vietnam, explains that the map and estimates produced by Hay's group set the benchmark for the disease: 'This is the first systematic robust estimate of the extent of dengue. (ox.ac.uk)
Jimmy Whitworth, Head of International Activities at the Wellcome Trust, said: 'Over time, this comprehensive map of global disease burden will also help to demonstrate which control measures are making the biggest difference in reducing the number of people suffering from dengue infection. (ox.ac.uk)
Dengue, also known as "tropical flu", is continuing to spread rapidly across the world and is now considered as a re-emerging disease. (pasteur.fr)
Through our new collaboration, we together have made a commitment to help protect people around the world who are at risk of developing dengue virus disease. (merck.com)
Whether the concurrent dengue viral infection is correlated with disease severity in a given population is another aspect to be pursued. (bvsalud.org)
Noting that dengue vaccine can be used in the country if the World Health Organization (WHO) approves after trial, the minister mentioned that researchers from the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b) and the Larner College of Medicine at the University of Vermont (UVM), USA, initiated groundbreaking studies on a promising tetravalent dengue vaccine in dengue-endemic Bangladesh. (tbsnews.net)
Therefore, health education about dengue virus infection should always done to all community for understanding to prevent this disease. (unair.ac.id)
The health authorities Wednesday tentatively concluded a patient with Dengue fever had been infected by the tropical disease during her trip to Indonesia. (blogspot.com)
To put this into perspective, consider this-dengue infections last for an average of two weeks and incur twice as much the average daily cost of managing a chronic disease like tuberculosis, which lasts for about 72 days. (researchmatters.in)
The dengue vaccine is the latest 'preventive' arsenal we have against the disease. (researchmatters.in)
This paper discusses the importance of Dengue Fever (DF) as an emerging disease in the world. (rjptonline.org)
3. Sharifi Mood B, Mardani M, Dengue: A Re-Emerging Disease. (rjptonline.org)
16. Rasheed S, Butlin R, Boots M A review of dengue as an emerging disease in Pakistan. (rjptonline.org)

Dengue varies in severity. (msdmanuals.com)

Organisms4

Diseases2

Chemicals and Drugs7

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Phenomena and Processes2

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Health Care5

Geographicals13

Hemorrhagic19

Serotypes17

Infected with dengue virus4

Spread of dengue3

DENV19

Aedes11

Mosquitoes11

Symptoms18

20194

Antibodies25

20232

Mosquito-borne7

Abstract1

Burden of dengue3

Zika18

Viruses11

Vaccine against the dengue virus1

Shock syndrome4

Risk of dengue virus1

Types of dengue virus1

Centers for Diseas1

Malaria3

Million dengue infections2

Acute5

Asymptomatic2

Severe dengue infection1

Previous dengue infection1

Immunity5

Epidemics2

Tropical and subtropical1

Breakbone fever1

Prevention4

Reducing dengue illness1

Illness1

Case of dengue2

Viral disease3

Diagnosis of dengue2

Treatment for dengue1

Serotype4

Cases31

Manifestations of Dengue2

Incidence5

Form of dengue1

Presence of dengue1

India6

Prevent dengue1

Endemic areas2

Occur1

20221

Disease16

Severity1