• Nelfinavir and simple derivatives have been found to inhibit the production of the virulence factor streptolysin S, a cytolysin produced by the human pathogen Streptococcus pyogenes. (wikipedia.org)
  • Due to an increase in the occurrence of Chagas' disease/AIDS co-infection, we decided to explore the effects of HIV aspartic peptidase inhibitors (HIV-PIs) on Trypanosoma cruzi, the etiologic agent of Chagas' disease. (semanticscholar.org)
  • Presence of a newly diagnosed AIDS-defining opportunistic infection requiring acute therapy at the time of enrollment. (clinicaltrials.gov)
  • Nelfinavir is a prescription medication used to treat human immunodeficiency virus (HIV) infection. (rxwiki.com)
  • The human immunodeficiency virus (HIV) infection has spread worldwide, with various adverse health and economic implications, particularly in the developing world. (harvard.edu)
  • 9, 10, 11) The clinical presentation of HIV related diseases may be modified by HAART, which has dramatically improved the prognosis of HIV infection. (harvard.edu)
  • In the United States, about three dozen clinical trials are being conducted (or have been completed) in order to determine whether nelfinavir is effective as a cancer therapeutic agent in humans. (wikipedia.org)
  • For example, during admission to hospital after a serious accident, before an operation, during an acute attack of asthma or if you have a chest infection or other serious illness. (drugs.com)
  • The occurrence of ophthalmic complications associated with HIV infection is significantly lower in the pediatric age group. (harvard.edu)
  • Since 2009, nelfinavir has been under investigation for potential use as an anti-cancer agent. (wikipedia.org)
  • In some of these trials, nelfinavir is used alone in monotherapy fashion, whereas in others it is combined with other modes of cancer therapy, such as well-established chemotherapeutic agents or radiation therapy. (wikipedia.org)
  • What tips would you provide a friend before taking Nelfinavir? (rxwiki.com)
  • Although first-line therapies for HIV-infection provide excellent rates of virologic control, ART toxicities remain a challenge. (springer.com)
  • If you get a cold or other infection while receiving this medicine, call your doctor or health care professional. (ahealthyme.com)
  • If you have an infection in your chest your doctor may prescribe a course of antibiotics. (drugs.com)