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  • preterm infants
  • Among preterm infants, the delay is believed to protect from intraventricular hemorrhage , or bleeding in the ventricles - the cavities inside the infant's brain. (healthcanal.com)
  • However, Dr. Anup C. Katheria, M.D., a neonatologist at the Neonatal Research Institute at the Sharp Mary Birch Hospital and the study's first author, noted that some studies failed to find a reduction in intraventricular hemorrhage from delayed cord clamping among preterm infants delivered by cesarean. (healthcanal.com)
  • morbidity and morta
  • 2 Introduction Early onset Group B Streptococcus (GBS) A leading cause of preventable neonatal morbidity and mortality Adverse Events 25% to 35% of infants develop neurological and physiological consequences Increased risk with waiting for clinical signs Rapid, accurate detection with early initiation of antibiotics is essential. (docplayer.net)
  • In low and middle income countries, human immunodeficiency virus (HIV) exposed, uninfected (HEU) infants demonstrate higher morbidity and mortality than their unexposed counterparts. (springeropen.com)
  • Elevated pro-inflammatory signals at birth may interfere with T cell responses at birth and subsequently influence immune maturation and the risk of morbidity and mortality in HEU infants. (springeropen.com)
  • These infants experience increased rates of morbidity and mortality compared with their HIV unexposed (HU) counterparts. (springeropen.com)
  • cohort
  • To determine possible immune correlates of this effect, we investigated the impact of in utero HIV exposure on the uninfected neonatal immune milieu and maternal factors mediating these abnormalities in a cohort of vaginally delivered mother-infants. (springeropen.com)
  • Samples of delivery and cord blood plasma were selected from 22 Kenyan HIV-infected women and their HIV exposed uninfected (HEU) infants drawn from the pre-ARV era, while 19 Kenyan HIV-uninfected (HU) women and their infants were selected from a control cohort. (springeropen.com)
  • A subgroup of the cohort will have 3D facial photography of their child at 12 months and a comprehensive developmental assessment (Bayley Scales of Infant & Toddler Development, Bayley-III) at two years of age. (biomedcentral.com)
  • samples
  • Investigation of 100 cord blood samples showed that passively transferred maternal poliovirus neutralising antibody cannot be relied upon for protection of infants against poliomyelitis. (nus.edu.sg)
  • Altered lymphocyte markers and blastogenic response associated with 24 hour delay in processing of blood samples. (currentprotocols.com)
  • CBMC
  • Higher CBMC PspA-IL-5 and PspA-IL-13 responses correlated with a higher proportion of cord CD4 T cells, and higher dPly-IL-6 responses with a higher frequency of cord antigen-presenting cells. (vanopijnenlab.com)
  • transplantation
  • Because there is diminished risk of graft-versus-host disease after transplantation of cord stem cells using matched related donors, the use of less-than-completely matched HLA cord blood stem cells may incur less risk of graft-versus-host disease than mismatched cells from either a related or unrelated "walking" donor, although this remains to be proven. (aappublications.org)
  • 19 - 23 With advances in the clinical practice of cord blood transplantation, most patients unable to find a fully matched adult donor can identify a partially matched cord blood donor. (aappublications.org)
  • The 1-year survival may be as high as 75% to 90% after sibling HLA-matched cord blood donor stem cell transplantation 21 , 24 , 29 and 40% to 80% after unrelated cord blood stem cell transplantation. (aappublications.org)
  • The AAP does recommend cord blood banking if an infant has a full sibling with a malignant or genetic condition treatable with cord blood transplantation. (webmd.com)
  • scientists
  • Sequencing these receptors in both adults and infants, the scientists found surprising overlaps that could provide potential new antibody targets for vaccines and therapeutics that work across populations. (news-medical.net)
  • METHODS
  • METHODS : Maternal venous and cord blood (CB) specimens were obtained from eighty-seven pregnant women (45 HIV-infected and 42 HIV-uninfected) enrolled at Kalafong Hospital, Pretoria, South Africa. (up.ac.za)
  • immune
  • Differences between maternal and infant cytokine levels strongly suggest independent modulation in utero, consistent with prenatal immune activation. (springeropen.com)
  • However, there is controversy in the field as to the cause of the observed immune changes in HEU infants, the relative contribution of maternal health, and relative differences observed in HIV unexposed infants from the same communities. (springeropen.com)
  • Cord blood Streptococcus pneumoniae-specific cellular immune responses predict early pneumococcal carriage in high-risk infants in Papua New Guinea. (vanopijnenlab.com)
  • Pneumococcus-specific cellular immune responses differ between children born in pneumococcal high versus low endemic settings, which may contribute to the higher risk of infants in high endemic settings for early pneumococcal colonization, and hence disease. (vanopijnenlab.com)
  • child's
  • Some parents choose to bank their child's blood if they don't know his or her medical background -- for instance, if a parent was adopted or the child was conceived with a sperm or egg donor. (webmd.com)
  • Banking
  • This document is intended to provide information to guide physicians in responding to parents' questions about cord blood donation and banking and the types and quality of cord blood banks. (aappublications.org)
  • Provided also are recommendations about appropriate ethical and operational standards, including informed consent policies, financial disclosures, and conflict-of-interest policies for physicians, institutions, and organizations that operate or have a relationship with cord blood-banking programs. (aappublications.org)
  • Cord blood banking can be a priceless investment. (webmd.com)
  • Both the American Academy of Pediatrics (AAP) and American Medical Association (AMA) recommend public cord blood banking over private cord blood banking. (webmd.com)
  • Public cord blood banking is free. (webmd.com)
  • The American College of Obstetricians and Gynecologis ts (ACOG) neither recommends nor advises against co rd blood banking. (webmd.com)
  • But along with the AAP and AMA, it cautions parents about private cord blood banking. (webmd.com)
  • Are there situations where private cord blood banking might make sense? (webmd.com)
  • Birth Weight
  • We assessed infant anthropometrics at birth (weight, length, head circumference) and maternal pregnancy medical history, including gestational diabetes mellitus, hypertension and weight gain. (parentsguidecordblood.org)
  • Rosenkrantz TS, Diana D, Munson J. Regulation of cerebral blood flow velocity in nonasphyxiated, very low birth weight infants with hyaline membrane disease. (medscape.com)
  • infection
  • One fifth of Indigenous infants born in the Northern Territory are hospitalised with an acute lower respiratory infection (ALRI) during their first year of life. (mja.com.au)
  • vein
  • Of the infants undergoing cesarean deliveries, those in the cord milking group had higher blood flow in the superior vena cava, the large vein carrying blood from the brain to the heart, and a higher output of blood from the right ventricle. (healthcanal.com)
  • participants
  • Participants will be followed up at 12 and 24 months after birth to assess child health and measure infant behavioural and sensory difficulties, as well as family environment and parenting styles. (biomedcentral.com)
  • risk
  • Only a few risk factors for accelerated shortening have been identified because there have been few studies of telomere length conducted with infants and young children. (parentsguidecordblood.org)
  • Infants with HIE are also at risk for pulmonary hypertension and should be monitored. (medscape.com)
  • higher
  • These benefits, which include greater blood flow to and from the heart, higher red blood cell level, and higher blood pressure, were seen only in the infants delivered by cesarean. (healthcanal.com)
  • In comparison to cord blood, cord tissue showed higher inter-individual variability in the epigenome, with a lower proportion of CpGs influenced by genotype. (biomedcentral.com)