ApoptosisCell ProliferationCaspasesApoptosis Regulatory ProteinsCaspase 3Proto-Oncogene Proteins c-bcl-2Cell Line, TumorInhibitor of Apoptosis ProteinsCells, CulturedSignal TransductionCell SurvivalDNA FragmentationIn Situ Nick-End Labelingbcl-2-Associated X ProteinTumor Cells, CulturedCell LineX-Linked Inhibitor of Apoptosis ProteinEnzyme InductionCell DivisionCell CycleEnzyme ActivationBlotting, WesternTumor Suppressor Protein p53Apoptosis Inducing FactorRNA, MessengerCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Caspase InhibitorsFlow CytometryMitochondriaCaspase 8Fas Ligand ProteinMice, Inbred C57BLProto-Oncogene ProteinsTransfectionCell DifferentiationCytochromes cDose-Response Relationship, Drugbcl-X ProteinAntineoplastic AgentsPhosphorylationRNA, Small InterferingEnzyme InhibitorsDown-RegulationGene Expression RegulationTime FactorsReverse Transcriptase Polymerase Chain ReactionUp-RegulationAnnexin A5ImmunohistochemistryMice, KnockoutCysteine Proteinase InhibitorsAmino Acid Chloromethyl KetonesReactive Oxygen SpeciesGene Expression Regulation, NeoplasticTumor Necrosis Factor-alphaPoly(ADP-ribose) PolymerasesProto-Oncogene Proteins c-aktGene ExpressionCell DeathDNA-Binding ProteinsNF-kappa BJurkat CellsTranscription FactorsMolecular Sequence DataHL-60 CellsFibroblastsT-LymphocytesEpithelial CellsMembrane GlycoproteinsMice, TransgenicProtein-Serine-Threonine KinasesTNF-Related Apoptosis-Inducing LigandRNA InterferenceLymphocyte ActivationMice, Inbred BALB CDNA DamageMutationCaspase 7Rats, Sprague-DawleyMembrane Potential, MitochondrialMitogen-Activated Protein KinasesCarrier ProteinsMice, NudeNeoplasm ProteinsBase SequenceDrug SynergismNecrosisGenes, bcl-2Membrane ProteinsModels, BiologicalCyclin-Dependent Kinase Inhibitor p21Disease Models, AnimalTranscription, GeneticCell MovementHeLa CellsRecombinant ProteinsCell NucleusNuclear Proteinsbcl-2 Homologous Antagonist-Killer Protein