Cell CycleCell AgingCell Cycle ProteinsApoptosisTumor Suppressor Protein p53Cell Cycle CheckpointsCell Line, TumorCells, CulturedCyclin-Dependent Kinase Inhibitor p21Cell ProliferationSignal TransductionCell DivisionCyclin-Dependent Kinase Inhibitor p16FibroblastsCell LineCaspasesDNA DamageEnzyme InductionApoptosis Regulatory ProteinsCaspase 3G1 PhaseProto-Oncogene Proteins c-bcl-2Cell SurvivalRetinoblastoma ProteinCyclinsRNA, MessengerTumor Cells, CulturedGene Expression RegulationTelomereMitosisAgingBlotting, WesternInhibitor of Apoptosis ProteinsDNA-Binding ProteinsFlow CytometryTime FactorsPhosphorylationDNA FragmentationProtein-Serine-Threonine KinasesDown-RegulationS PhasePlant LeavesTranscription FactorsTelomeraseMolecular Sequence DataMutationTumor Suppressor ProteinsRNA, Small InterferingEnzyme ActivationNuclear Proteinsbcl-2-Associated X Proteinbeta-GalactosidaseG2 PhaseModels, BiologicalTransfectionReactive Oxygen SpeciesUp-RegulationIn Situ Nick-End LabelingCyclin-Dependent Kinase Inhibitor p27Reverse Transcriptase Polymerase Chain ReactionProto-Oncogene ProteinsMitochondriaAntineoplastic AgentsG2 Phase Cell Cycle CheckpointsCell DifferentiationRNA InterferenceTranscription, GeneticCell NucleusBase SequenceOxidative StressAging, PrematureEnzyme InhibitorsMice, Inbred C57BLGene Expression Regulation, NeoplasticHeLa CellsGene ExpressionPhenotypeDose-Response Relationship, DrugCell Transformation, NeoplasticMice, KnockoutPromoter Regions, GeneticX-Linked Inhibitor of Apoptosis ProteinCell DeathAmino Acid SequenceG0 PhaseMenstrual CycleCaspase 9DNACaspase InhibitorsGene Expression ProfilingCarrier ProteinsApoptosis Inducing FactorProtein BindingCyclin D1Cyclin-Dependent Kinase 2ImmunohistochemistryCell Line, TransformedCASP8 and FADD-Like Apoptosis Regulating ProteinG1 Phase Cell Cycle CheckpointsNeoplasms