Nitric Oxide SynthaseNitric Oxide Synthase Type IIGene Expression Regulation, EnzymologicNitric OxideAmino Acid OxidoreductasesNitric Oxide Synthase Type IIIRNA, MessengerNitric Oxide Synthase Type INitritesEnzyme InductionLipopolysaccharidesPromoter Regions, GeneticGene ExpressionInterferon-gammaNF-kappa BEnzyme InhibitorsCells, CulturedMacrophagesEndothelium, VascularGene Expression Regulationomega-N-MethylarginineHydroxymethylglutaryl-CoA SynthaseArgininePolymorphism, GeneticMolecular Sequence DataRats, Sprague-DawleyBase SequenceNG-Nitroarginine Methyl EsterNitric Oxide DonorsIsothiuroniumNitratesInterleukin-1Gene Expression ProfilingTranscription, GeneticMice, Inbred C57BLGuanidinesThymidylate SynthaseMice, KnockoutGenotypeReverse Transcriptase Polymerase Chain ReactionPolymerase Chain ReactionTumor Necrosis Factor-alphaCell LineCyclooxygenase 2AmidinesFatty Acid SynthasesGene FrequencyRats, WistarGenetic Predisposition to DiseaseBlotting, WesternImmunohistochemistryAllelesDNA PrimersNitroarginineHeterocyclic Compounds, 2-RingCyclic GMPIntronsGene Expression Regulation, PlantTranscription FactorsNADPH DehydrogenaseDose-Response Relationship, DrugProstaglandin-Endoperoxide SynthasesGene Transfer TechniquesDisease Models, AnimalBiopterinRecombinant ProteinsCase-Control StudiesPolymorphism, Single NucleotideSignal TransductionCytokinesIsoenzymesVasodilationArginasePeroxynitrous AcidPenicillamineS-Nitroso-N-AcetylpenicillamineCitrullineTime FactorsTandem Repeat SequencesHaplotypesTransfectionIndazolesUp-RegulationOxidative StressMacrophage ActivationNitroprussideAdenoviridaeCitrate (si)-SynthaseMacrophages, PeritonealReactive Nitrogen SpeciesHypertensionMinisatellite RepeatsAortaTyrosineNitrogen OxidesInflammationLungHomozygoteOligonucleotide Array Sequence AnalysisDNA