Induces tumor cell apoptosis. Medical search. Frequent questions

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Anatomy24

Cell Line, Tumor Tumor Cells, Cultured Mitochondria Cells, Cultured Cell Line Endothelial Cells Neoplastic Cells, Circulating Epithelial Cells Jurkat Cells T-Lymphocytes HeLa Cells HL-60 Cells Fibroblasts Cell Nucleus HCT116 Cells Macrophages Endothelium, Vascular HT29 Cells Cell Line, Transformed Neoplastic Stem Cells K562 Cells Killer Cells, Natural U937 Cells Lymphocytes

Organisms10

Mice, Nude Mice, Inbred BALB C Mice, Inbred C57BL Mice, SCID Adenoviridae Mice, Knockout Mice, Transgenic Rats, Sprague-Dawley Mice, Inbred Strains Rats, Inbred F344

Diseases46

Neovascularization, Pathologic Neoplasms Neoplasms, Experimental Mammary Neoplasms, Experimental Colonic Neoplasms Adenocarcinoma Breast Neoplasms Liver Neoplasms Disease Models, Animal Necrosis Ovarian Neoplasms Neoplasm Metastasis Lung Neoplasms Pancreatic Neoplasms Carcinoma, Hepatocellular Brain Neoplasms Carcinoma, Ehrlich Tumor Melanoma Wilms Tumor Disease Progression Fibrosarcoma Neoplastic Cells, Circulating Carcinoid Tumor Cell Transformation, Neoplastic Melanoma, Experimental Glioma Neuroendocrine Tumors Prostatic Neoplasms Sarcoma, Experimental Skin Neoplasms Glioblastoma Carcinoma, Squamous Cell Kidney Neoplasms Neuroblastoma Mammary Neoplasms, Animal Bone Neoplasms Gastrointestinal Stromal Tumors Lymphoma Liver Neoplasms, Experimental Neoplasm Invasiveness Osteosarcoma Stomach Neoplasms Urinary Bladder Neoplasms Leydig Cell Tumor Carcinoma, Lewis Lung Carcinoma, Renal Cell

Chemicals and Drugs93

Caspase 3 Caspases Apoptosis Regulatory Proteins Proto-Oncogene Proteins c-bcl-2 Antineoplastic Agents Tumor Suppressor Protein p53 Inhibitor of Apoptosis Proteins Tumor Necrosis Factor-alpha TNF-Related Apoptosis-Inducing Ligand RNA, Small Interfering Cytochromes c Tumor Markers, Biological Neoplasm Proteins bcl-2-Associated X Protein Fas Ligand Protein Receptors, TNF-Related Apoptosis-Inducing Ligand Angiogenesis Inhibitors RNA, Messenger Furans Caspase 9 Enzyme Inhibitors Antibodies, Monoclonal Caspase Inhibitors Caspase 8 X-Linked Inhibitor of Apoptosis Protein Antineoplastic Agents, Phytogenic Tumor Suppressor Proteins Proto-Oncogene Proteins Membrane Glycoproteins CASP8 and FADD-Like Apoptosis Regulating Protein Doxorubicin Microtubule-Associated Proteins bcl-X Protein Apoptosis Inducing Factor Annexin A5 Antigens, Neoplasm Recombinant Proteins Reactive Oxygen Species Poly(ADP-ribose) Polymerases Amino Acid Chloromethyl Ketones Benzenesulfonates Proto-Oncogene Proteins c-akt NF-kappa B Cysteine Proteinase Inhibitors DNA, Neoplasm Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor Receptor-2 Antigens, CD95 Caspase 7 Membrane Proteins DNA-Binding Proteins Protein-Serine-Threonine Kinases Carrier Proteins Pyridines Transcription Factors Receptors, Tumor Necrosis Factor, Type I Cisplatin Antibiotics, Antineoplastic RNA, Neoplasm bcl-2 Homologous Antagonist-Killer Protein Myeloid Cell Leukemia Sequence 1 Protein DNA Primers Proteins Cytokines Phosphatidylinositol 3-Kinases Staurosporine bcl-Associated Death Protein Ceramides Mitogen-Activated Protein Kinases Cyclin-Dependent Kinase Inhibitor p21 Cytochrome c Group Interferon-gamma BH3 Interacting Domain Death Agonist Protein Cancer Vaccines Ki-67 Antigen Intracellular Signaling Peptides and Proteins p38 Mitogen-Activated Protein Kinases Oligopeptides Recombinant Fusion Proteins Radiation-Sensitizing Agents DNA Caspase 2 Protein Kinase Inhibitors Hydrogen Peroxide Cell Cycle Proteins Etoposide Fas-Associated Death Domain Protein Proto-Oncogene Proteins c-myc Cysteine Endopeptidases Indoles Adaptor Proteins, Signal Transducing Receptors, Tumor Necrosis Factor Oligonucleotides, Antisense

Analytical, Diagnostic and Therapeutic Techniques and Equipment36

In Situ Nick-End Labeling Xenograft Model Antitumor Assays Tumor Burden Neoplasm Transplantation Neoplasms, Experimental Blotting, Western Mammary Neoplasms, Experimental Flow Cytometry Transplantation, Heterologous Immunohistochemistry Transfection Reverse Transcriptase Polymerase Chain Reaction Disease Models, Animal Genetic Therapy Drug Screening Assays, Antitumor Melanoma, Experimental Antineoplastic Combined Chemotherapy Protocols Sarcoma, Experimental Models, Biological Gene Expression Profiling Immunoenzyme Techniques Immunotherapy Gene Knockdown Techniques Tumor Stem Cell Assay Immunoblotting Neoplasm Staging Coculture Techniques Liver Neoplasms, Experimental Microscopy, Fluorescence Lymphocyte Activation Polymerase Chain Reaction Fluorescent Antibody Technique Real-Time Polymerase Chain Reaction Combined Modality Therapy Treatment Outcome Enzyme-Linked Immunosorbent Assay

Phenomena and Processes51

Apoptosis Cell Proliferation Cell Survival Signal Transduction Cell Division Gene Expression Regulation, Neoplastic DNA Fragmentation Enzyme Activation Transfection Down-Regulation Dose-Response Relationship, Drug Cell Cycle Drug Synergism Time Factors Phosphorylation Necrosis Cell Growth Processes Cell Movement RNA Interference Genes, Tumor Suppressor Cell Hypoxia Up-Regulation Tumor Microenvironment Cell Death Genetic Vectors Gene Expression Mutation Membrane Potential, Mitochondrial Base Sequence DNA Damage Gene Expression Regulation Cytotoxicity, Immunologic Genes, p53 Cell Adhesion Cell Differentiation Oxidative Stress Genes, bcl-2 Protein Binding Drug Resistance, Neoplasm Gene Silencing Radiation Tolerance Promoter Regions, Genetic Transcription, Genetic Amino Acid Sequence Phenotype Lymphocyte Activation MAP Kinase Signaling System Cell Cycle Checkpoints Tissue Distribution Gamma Rays Autophagy

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care1

Treatment Outcome

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Apoptosis Cell Line, Tumor Tumor Cells, Cultured In Situ Nick-End Labeling Caspase 3 Caspases Cell Proliferation Mice, Nude Xenograft Model Antitumor Assays Apoptosis Regulatory Proteins Proto-Oncogene Proteins c-bcl-2 Cell Survival Antineoplastic Agents Neovascularization, Pathologic Tumor Suppressor Protein p53 Inhibitor of Apoptosis Proteins Signal Transduction Tumor Burden Tumor Necrosis Factor-alpha Neoplasms Neoplasm Transplantation Neoplasms, Experimental Mice, Inbred BALB C Cell Division Gene Expression Regulation, Neoplastic Blotting, Western TNF-Related Apoptosis-Inducing Ligand Mammary Neoplasms, Experimental Flow Cytometry Transplantation, Heterologous RNA, Small Interfering Mice, Inbred C57BL Immunohistochemistry Cytochromes c Tumor Markers, Biological Neoplasm Proteins Colonic Neoplasms DNA Fragmentation bcl-2-Associated X Protein Adenocarcinoma Enzyme Activation Transfection Mice, SCID Reverse Transcriptase Polymerase Chain Reaction Mitochondria Cells, Cultured Fas Ligand Protein Cell Line Down-Regulation Dose-Response Relationship, Drug Cell Cycle Receptors, TNF-Related Apoptosis-Inducing Ligand Breast Neoplasms Drug Synergism Angiogenesis Inhibitors Time Factors RNA, Messenger Phosphorylation Liver Neoplasms Furans Caspase 9 Enzyme Inhibitors Disease Models, Animal Genetic Therapy Antibodies, Monoclonal Caspase Inhibitors Necrosis Caspase 8 Drug Screening Assays, Antitumor Cell Growth Processes Ovarian Neoplasms Cell Movement Neoplasm Metastasis X-Linked Inhibitor of Apoptosis Protein Antineoplastic Agents, Phytogenic RNA Interference Lung Neoplasms Tumor Suppressor Proteins Genes, Tumor Suppressor Pancreatic Neoplasms Carcinoma, Hepatocellular Proto-Oncogene Proteins Membrane Glycoproteins Brain Neoplasms Adenoviridae CASP8 and FADD-Like Apoptosis Regulating Protein Cell Hypoxia Doxorubicin Microtubule-Associated Proteins bcl-X Protein Up-Regulation Carcinoma, Ehrlich Tumor Melanoma Wilms Tumor Endothelial Cells Apoptosis Inducing Factor Annexin A5 Antigens, Neoplasm Disease Progression Fibrosarcoma

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