Induces g1 arrest phases halts cell cycle progression. Medical search. Frequent questions

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Anatomy22

Cell Line, Tumor Cell Line Cells, Cultured Tumor Cells, Cultured HeLa Cells Cell Nucleus Fibroblasts 3T3 Cells NIH 3T3 Cells Spindle Apparatus Centrosome Chromatin Cytoplasm Microtubules HCT116 Cells Epithelial Cells Cell Line, Transformed Stem Cells Embryo, Mammalian Keratinocytes Embryo, Nonmammalian Centrioles

Organisms10

Saccharomyces cerevisiae Schizosaccharomyces Caulobacter crescentus Mice, Knockout Mice, Transgenic Mice, Inbred C57BL Mice, Nude Caulobacter Drosophila Cricetinae

Diseases8

Disease Progression Cell Transformation, Neoplastic Neoplasms Breast Neoplasms Prostatic Neoplasms Disease Models, Animal Genomic Instability Polyploidy

Chemicals and Drugs114

Cell Cycle Proteins Cyclins Retinoblastoma Protein Cyclin-Dependent Kinase Inhibitor p27 Cyclin-Dependent Kinases Cyclin D1 Cyclin-Dependent Kinase 2 Cyclin-Dependent Kinase Inhibitor p21 Cyclin E Protein-Serine-Threonine Kinases Cyclin A E2F Transcription Factors Cyclin-Dependent Kinase 4 CDC2 Protein Kinase CDC2-CDC28 Kinases DNA-Binding Proteins E2F1 Transcription Factor Cyclin B Tumor Suppressor Protein p53 Nuclear Proteins Tumor Suppressor Proteins Transcription Factors cdc25 Phosphatases Cyclin B1 Cyclin D RNA, Messenger Transcription Factor DP1 RNA, Small Interfering Retinoblastoma-Binding Protein 1 Protein Kinases DNA Proto-Oncogene Proteins Bromodeoxyuridine Mimosine Saccharomyces cerevisiae Proteins Antineoplastic Agents Cyclin D2 Cyclin D3 Enzyme Inhibitors Carrier Proteins Proto-Oncogene Proteins c-myc Cyclin-Dependent Kinase Inhibitor Proteins Cyclin-Dependent Kinase 6 Microtubule-Associated Proteins Proliferating Cell Nuclear Antigen Histones Ubiquitin-Protein Ligase Complexes Fungal Proteins Cyclin-Dependent Kinase Inhibitor p16 Anaphase-Promoting Complex-Cyclosome Recombinant Fusion Proteins DNA Primers E2F4 Transcription Factor Retinoblastoma-Like Protein p130 Retinoblastoma-Like Protein p107 E2F2 Transcription Factor Neoplasm Proteins S-Phase Kinase-Associated Proteins Repressor Proteins Checkpoint Kinase 2 Cyclin G E2F5 Transcription Factor Aphidicolin Hydroxyurea Schizosaccharomyces pombe Proteins Nocodazole Proteins E2F3 Transcription Factor Proto-Oncogene Proteins c-akt Trans-Activators Cyclin A2 Oncogene Proteins Phosphatidylinositol 3-Kinases Intracellular Signaling Peptides and Proteins Cyclin G1 CDC28 Protein Kinase, S cerevisiae Drosophila Proteins Mitogen-Activated Protein Kinases Growth Inhibitors F-Box Proteins Chromatin Recombinant Proteins Ubiquitin-Protein Ligases Proteasome Endopeptidase Complex Aurora Kinases Cullin Proteins Ataxia Telangiectasia Mutated Proteins Culture Media, Serum-Free Phosphoproteins Protein-Tyrosine Kinases Proto-Oncogene Proteins c-bcl-2 TOR Serine-Threonine Kinases Phosphoprotein Phosphatases Cyclin A1 Cyclin G2 Antineoplastic Agents, Phytogenic Kinetin Protein Kinase Inhibitors MicroRNAs DNA, Complementary Tubulin Proto-Oncogene Proteins c-mdm2 Adaptor Proteins, Signal Transducing Thymidine Chromosomal Proteins, Non-Histone Purines DNA, Fungal Ubiquitin DNA, Neoplasm Cyclin C Cyclin-Dependent Kinase Inhibitor p19 Mitogens Securin Green Fluorescent Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Flow Cytometry Blotting, Western Models, Biological Transfection Reverse Transcriptase Polymerase Chain Reaction Immunohistochemistry Gene Expression Profiling Microscopy, Fluorescence Oligonucleotide Array Sequence Analysis Immunoblotting Gene Knockdown Techniques Immunoprecipitation Two-Hybrid System Techniques Culture Media, Serum-Free Mitotic Index Disease Models, Animal Cloning, Molecular Precipitin Tests Fluorescent Antibody Technique Sequence Alignment Blotting, Northern

Phenomena and Processes82

Cell Cycle G1 Phase S Phase Cell Division Mitosis Cell Cycle Checkpoints Cell Proliferation G2 Phase Apoptosis Phosphorylation Signal Transduction G0 Phase Genes, cdc DNA Damage Mutation DNA Replication G2 Phase Cell Cycle Checkpoints Time Factors Gene Expression Regulation Down-Regulation G1 Phase Cell Cycle Checkpoints Cell Survival Transcription, Genetic Amino Acid Sequence Gene Expression Regulation, Neoplastic Base Sequence Interphase Transfection Protein Binding Cell Differentiation RNA Interference Promoter Regions, Genetic Gene Expression Enzyme Activation Phenotype Menstrual Cycle Up-Regulation M Phase Cell Cycle Checkpoints S Phase Cell Cycle Checkpoints Dose-Response Relationship, Drug Sequence Homology, Amino Acid Cell Size Kinetics DNA Repair Gene Expression Regulation, Developmental Transcriptional Activation Meiosis Protein Structure, Tertiary Cell Death Chromatin Gene Deletion Genes, Fungal Gene Expression Regulation, Fungal Gene Silencing Metaphase Cell Movement Binding Sites Anaphase Cytokinesis Genes, myc Ultraviolet Rays MAP Kinase Signaling System Protein Transport Cell Aging Genomic Instability Genes, Retinoblastoma Gamma Rays Protein Processing, Post-Translational Cell Growth Processes Chromosome Segregation Genes, Tumor Suppressor Plasmids Polyploidy Ubiquitination Cell Nucleus Division Gene Expression Regulation, Enzymologic Active Transport, Cell Nucleus Genes, p53 Estrous Cycle Acetylation Genes, Reporter Cell Adhesion

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Cell Cycle Cell Cycle Proteins Disease Progression G1 Phase S Phase Cyclins Cell Division Mitosis Cell Cycle Checkpoints Cell Proliferation Retinoblastoma Protein Cyclin-Dependent Kinase Inhibitor p27 G2 Phase Cyclin-Dependent Kinases Cyclin D1 Cyclin-Dependent Kinase 2 Cyclin-Dependent Kinase Inhibitor p21 Apoptosis Cell Line, Tumor Cyclin E Protein-Serine-Threonine Kinases Phosphorylation Signal Transduction Cyclin A E2F Transcription Factors Cyclin-Dependent Kinase 4 CDC2 Protein Kinase CDC2-CDC28 Kinases Cell Line DNA-Binding Proteins E2F1 Transcription Factor G0 Phase Cyclin B Molecular Sequence Data Tumor Suppressor Protein p53 Genes, cdc DNA Damage Nuclear Proteins Flow Cytometry Tumor Suppressor Proteins Transcription Factors Mutation cdc25 Phosphatases DNA Replication Cells, Cultured Cyclin B1 Cyclin D G2 Phase Cell Cycle Checkpoints Tumor Cells, Cultured Time Factors RNA, Messenger Blotting, Western Gene Expression Regulation HeLa Cells Transcription Factor DP1 Down-Regulation Models, Biological G1 Phase Cell Cycle Checkpoints Cell Survival Cell Nucleus Transcription, Genetic Amino Acid Sequence Gene Expression Regulation, Neoplastic Base Sequence Interphase RNA, Small Interfering Transfection Retinoblastoma-Binding Protein 1 Protein Binding Protein Kinases DNA Proto-Oncogene Proteins Saccharomyces cerevisiae Bromodeoxyuridine Mimosine Cell Differentiation Saccharomyces cerevisiae Proteins Fibroblasts Antineoplastic Agents Cyclin D2 Cyclin D3 Enzyme Inhibitors RNA Interference Carrier Proteins Reverse Transcriptase Polymerase Chain Reaction Proto-Oncogene Proteins c-myc 3T3 Cells Cyclin-Dependent Kinase Inhibitor Proteins Cyclin-Dependent Kinase 6 Microtubule-Associated Proteins Promoter Regions, Genetic Proliferating Cell Nuclear Antigen Histones Ubiquitin-Protein Ligase Complexes Cell Transformation, Neoplastic Fungal Proteins Gene Expression Cyclin-Dependent Kinase Inhibitor p16 Immunohistochemistry Enzyme Activation

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