Induces either apoptosis. Medical search. Frequent questions

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Anatomy31

Cell Line, Tumor Mitochondria Tumor Cells, Cultured Cells, Cultured Cell Line Jurkat Cells HL-60 Cells HeLa Cells Epithelial Cells Cell Nucleus U937 Cells Fibroblasts T-Lymphocytes Mitochondrial Membranes Cell Line, Transformed K562 Cells HCT116 Cells Neurons Hepatocytes Endoplasmic Reticulum HT29 Cells Macrophages Lymphocytes Cytosol Myocytes, Cardiac Endothelial Cells Thymus Gland Intracellular Membranes Neutrophils Endothelium, Vascular Keratinocytes

Organisms9

Mice, Inbred C57BL Mice, Knockout Mice, Nude Rats, Sprague-Dawley Mice, Transgenic Mice, Inbred BALB C Adenoviridae Rats, Wistar Mice, SCID

Diseases12

Necrosis Disease Models, Animal Colonic Neoplasms Prostatic Neoplasms Neoplasms Breast Neoplasms Carcinoma, Hepatocellular Neuroblastoma Cell Transformation, Neoplastic Melanoma Lung Neoplasms Liver Neoplasms

Chemicals and Drugs134

Apoptosis Regulatory Proteins Caspases Caspase 3 Inhibitor of Apoptosis Proteins Proto-Oncogene Proteins c-bcl-2 bcl-2-Associated X Protein X-Linked Inhibitor of Apoptosis Protein Apoptosis Inducing Factor CASP8 and FADD-Like Apoptosis Regulating Protein Caspase 9 Caspase Inhibitors Caspase 8 Fas Ligand Protein Tumor Suppressor Protein p53 Cytochromes c bcl-X Protein Annexin A5 Amino Acid Chloromethyl Ketones Cysteine Proteinase Inhibitors Proto-Oncogene Proteins Antineoplastic Agents Poly(ADP-ribose) Polymerases Enzyme Inhibitors TNF-Related Apoptosis-Inducing Ligand Reactive Oxygen Species RNA, Small Interfering Caspase 7 Tumor Necrosis Factor-alpha bcl-2 Homologous Antagonist-Killer Protein Membrane Glycoproteins Cytochrome c Group Myeloid Cell Leukemia Sequence 1 Protein RNA, Messenger BH3 Interacting Domain Death Agonist Protein NF-kappa B Proto-Oncogene Proteins c-akt Staurosporine bcl-Associated Death Protein Antineoplastic Agents, Phytogenic Ceramides Receptors, TNF-Related Apoptosis-Inducing Ligand Protein-Serine-Threonine Kinases Carrier Proteins Caspase 2 Fas-Associated Death Domain Protein Neoplasm Proteins Cysteine Endopeptidases Apoptotic Protease-Activating Factor 1 Mitogen-Activated Protein Kinases Membrane Proteins DNA-Binding Proteins Receptors, Tumor Necrosis Factor Caspase 1 Intracellular Signaling Peptides and Proteins p38 Mitogen-Activated Protein Kinases Cyclin-Dependent Kinase Inhibitor p21 Etoposide MAP Kinase Kinase Kinase 5 Hydrogen Peroxide Proteins Tumor Suppressor Proteins Phosphatidylinositol 3-Kinases Transcription Factors Nuclear Proteins Propidium Culture Media, Serum-Free Receptors, Death Domain Recombinant Proteins Cell Cycle Proteins Transcription Factor CHOP Phosphatidylserines Cycloheximide Oligopeptides Microtubule-Associated Proteins Protein Synthesis Inhibitors Proto-Oncogene Proteins c-myc MAP Kinase Kinase 4 Acetylcysteine Doxorubicin Oligonucleotides, Antisense Antioxidants Adaptor Proteins, Signal Transducing Mitochondrial Proteins Tetrazolium Salts DNA Antibiotics, Antineoplastic DNA Primers Cyclins Flavonoids Glutathione Mitogen-Activated Protein Kinase 8 Receptors, Tumor Necrosis Factor, Type I Extracellular Signal-Regulated MAP Kinases Nucleic Acid Synthesis Inhibitors Recombinant Fusion Proteins Cisplatin Caspase 10 Oxides Chromones Morpholines Proteasome Endopeptidase Complex E2F1 Transcription Factor Sphingomyelin Phosphodiesterase Oxidants Pyrazines Arsenicals Plant Extracts Protein Kinase Inhibitors Indoles Imidazoles Tumor Necrosis Factors Death Domain Receptor Signaling Adaptor Proteins Sulfonamides Boronic Acids Proto-Oncogene Proteins c-mdm2 Mitogen-Activated Protein Kinase Kinases Thiazoles Curcumin Nitric Oxide Histone Deacetylase Inhibitors Hydroxamic Acids Piperazines Protein Kinase C-delta Fenretinide I-kappa B Proteins Cytokines Anticarcinogenic Agents Sphingosine Proliferating Cell Nuclear Antigen Stilbenes Pyridines Diterpenes Serpins Proteasome Inhibitors

Analytical, Diagnostic and Therapeutic Techniques and Equipment18

In Situ Nick-End Labeling Blotting, Western Flow Cytometry Transfection Reverse Transcriptase Polymerase Chain Reaction Immunohistochemistry Models, Biological Xenograft Model Antitumor Assays Immunoblotting Culture Media, Serum-Free Disease Models, Animal Drug Screening Assays, Antitumor Microscopy, Fluorescence Gene Knockdown Techniques Immunoprecipitation Gene Expression Profiling Microscopy, Confocal Cell Count

Phenomena and Processes51

Apoptosis DNA Fragmentation Cell Survival Signal Transduction Enzyme Activation Cell Proliferation Cell Cycle Transfection Cell Division Down-Regulation Membrane Potential, Mitochondrial Cell Death Dose-Response Relationship, Drug Genes, bcl-2 Phosphorylation Necrosis Up-Regulation DNA Damage Time Factors Gene Expression Regulation, Neoplastic Oxidative Stress Drug Synergism Gene Expression Regulation RNA Interference Gene Expression Drug Resistance, Neoplasm Mutation Cell Differentiation Protein Binding Cytoprotection Genes, p53 Autophagy MAP Kinase Signaling System Gamma Rays Cell Cycle Checkpoints Protein Transport Endoplasmic Reticulum Stress Base Sequence Amino Acid Sequence G1 Phase Transcription, Genetic G2 Phase Gene Silencing Cell Growth Processes Protein Structure, Tertiary Membrane Potentials Radiation Tolerance Cell Count Mitosis Promoter Regions, Genetic Transcriptional Activation

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Apoptosis Apoptosis Regulatory Proteins Caspases Caspase 3 Inhibitor of Apoptosis Proteins Proto-Oncogene Proteins c-bcl-2 DNA Fragmentation In Situ Nick-End Labeling bcl-2-Associated X Protein X-Linked Inhibitor of Apoptosis Protein Cell Line, Tumor Apoptosis Inducing Factor Cell Survival CASP8 and FADD-Like Apoptosis Regulating Protein Caspase 9 Caspase Inhibitors Signal Transduction Caspase 8 Mitochondria Fas Ligand Protein Tumor Suppressor Protein p53 Enzyme Activation Cytochromes c Tumor Cells, Cultured Cells, Cultured bcl-X Protein Annexin A5 Cell Proliferation Blotting, Western Amino Acid Chloromethyl Ketones Cysteine Proteinase Inhibitors Cell Line Proto-Oncogene Proteins Flow Cytometry Cell Cycle Antineoplastic Agents Poly(ADP-ribose) Polymerases Enzyme Inhibitors TNF-Related Apoptosis-Inducing Ligand Reactive Oxygen Species Jurkat Cells Transfection Cell Division RNA, Small Interfering Caspase 7 HL-60 Cells Down-Regulation Membrane Potential, Mitochondrial Cell Death Dose-Response Relationship, Drug Tumor Necrosis Factor-alpha Genes, bcl-2 Phosphorylation bcl-2 Homologous Antagonist-Killer Protein Membrane Glycoproteins Necrosis Cytochrome c Group Up-Regulation Myeloid Cell Leukemia Sequence 1 Protein RNA, Messenger BH3 Interacting Domain Death Agonist Protein NF-kappa B DNA Damage Proto-Oncogene Proteins c-akt Time Factors Staurosporine Reverse Transcriptase Polymerase Chain Reaction Mice, Inbred C57BL bcl-Associated Death Protein Gene Expression Regulation, Neoplastic Antineoplastic Agents, Phytogenic Ceramides Receptors, TNF-Related Apoptosis-Inducing Ligand Protein-Serine-Threonine Kinases Carrier Proteins Mice, Knockout Caspase 2 HeLa Cells Oxidative Stress Drug Synergism Immunohistochemistry Fas-Associated Death Domain Protein Neoplasm Proteins Gene Expression Regulation Cysteine Endopeptidases RNA Interference Apoptotic Protease-Activating Factor 1 Mitogen-Activated Protein Kinases Membrane Proteins Epithelial Cells Gene Expression DNA-Binding Proteins Receptors, Tumor Necrosis Factor Mice, Nude Caspase 1 Cell Nucleus U937 Cells Intracellular Signaling Peptides and Proteins Models, Biological Drug Resistance, Neoplasm

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