Induces apoptosis or senescence induces cell senescence. Medical search. Frequent questions

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Anatomy27

Telomere Cells, Cultured Fibroblasts Cell Line, Tumor Cell Line Endothelial Cells Plant Leaves Mitochondria Stem Cells Tumor Cells, Cultured Endothelium, Vascular Cell Line, Transformed Epithelial Cells HCT116 Cells Cell Nucleus Flowers HeLa Cells Jurkat Cells HL-60 Cells Keratinocytes Plant Stems Foreskin Embryo, Mammalian Melanocytes NIH 3T3 Cells Heterochromatin T-Lymphocytes

Organisms13

Mice, Inbred C57BL Mice, Knockout Arabidopsis Plants, Genetically Modified Mice, Nude Petunia Mice, Transgenic Rats, Sprague-Dawley Alstroemeria Dianthus Mice, Inbred BALB C Mice, Mutant Strains Ipomoea nil

Diseases12

Aging, Premature Cell Transformation, Neoplastic Atherosclerosis Neoplasms Necrosis Progeria Disease Models, Animal Melanoma Werner Syndrome Prostatic Neoplasms Breast Neoplasms Colonic Neoplasms

Chemicals and Drugs119

Cyclin-Dependent Kinase Inhibitor p16 Tumor Suppressor Protein p53 beta-Galactosidase Cyclin-Dependent Kinase Inhibitor p21 Telomerase Reactive Oxygen Species Apoptosis Regulatory Proteins Caspases Retinoblastoma Protein Caspase 3 Proto-Oncogene Proteins c-bcl-2 Inhibitor of Apoptosis Proteins RNA, Small Interfering TOR Serine-Threonine Kinases bcl-2-Associated X Protein p38 Mitogen-Activated Protein Kinases DNA-Binding Proteins X-Linked Inhibitor of Apoptosis Protein Cell Cycle Proteins RNA, Messenger Apoptosis Inducing Factor Histones CASP8 and FADD-Like Apoptosis Regulating Protein Caspase 9 Caspase Inhibitors Caspase 8 Tumor Suppressor Proteins Fas Ligand Protein Cytochromes c bcl-X Protein Proto-Oncogene Proteins Annexin A5 Antineoplastic Agents Chlorophyll Biological Markers Ethylenes Protein-Serine-Threonine Kinases Hydrogen Peroxide Nuclear Proteins Enzyme Inhibitors Cysteine Proteinase Inhibitors Tumor Suppressor Protein p14ARF Poly(ADP-ribose) Polymerases Transcription Factors Amino Acid Chloromethyl Ketones Sirtuin 1 Proto-Oncogene Proteins c-akt ras Proteins Plant Growth Regulators Plant Proteins Proto-Oncogene Proteins c-myc Arabidopsis Proteins Neoplasm Proteins Carrier Proteins TNF-Related Apoptosis-Inducing Ligand Intracellular Signaling Peptides and Proteins NF-kappa B Cyclins Tumor Necrosis Factor-alpha Cytokinins Cysteine Endopeptidases Oxidants Caspase 7 Repressor Proteins Doxorubicin Telomeric Repeat Binding Protein 2 Antineoplastic Agents, Phytogenic Ceramides Proteins Cyclopentanes bcl-2 Homologous Antagonist-Killer Protein Membrane Glycoproteins Membrane Proteins Acetylcysteine Cytochrome c Group Antioxidants Myeloid Cell Leukemia Sequence 1 Protein BH3 Interacting Domain Death Agonist Protein Oxylipins Mitogen-Activated Protein Kinases MicroRNAs Cyclin-Dependent Kinase Inhibitor p15 Staurosporine Phosphatidylinositol 3-Kinases Oncogene Protein p21(ras)Proto-Oncogene Proteins c-mdm2 DNA Antibiotics, Antineoplastic Etoposide Ataxia Telangiectasia Mutated Proteins Culture Media, Serum-Free Imidazoles DNA Primers bcl-Associated Death Protein Cyclin-Dependent Kinase Inhibitor p27 Receptors, TNF-Related Apoptosis-Inducing Ligand Caspase 2 Fas-Associated Death Domain Protein Cyclin-Dependent Kinase Inhibitor p19 Microtubule-Associated Proteins Recombinant Proteins E2F1 Transcription Factor Cyclin-Dependent Kinase 6 Proto-Oncogene Proteins p21(ras)Cyclin-Dependent Kinases Apoptotic Protease-Activating Factor 1 Proteasome Endopeptidase Complex Polycomb Repressive Complex 1 Piperazines Cyclin-Dependent Kinase 4 Heterochromatin RNA, Plant Extracellular Signal-Regulated MAP Kinases Propidium Receptors, Tumor Necrosis Factor Caspase 1 Adaptor Proteins, Signal Transducing Protein Kinase Inhibitors Stilbenes

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Blotting, Western Flow Cytometry In Situ Nick-End Labeling Reverse Transcriptase Polymerase Chain Reaction Transfection Immunohistochemistry Models, Biological Gene Knockdown Techniques Gene Expression Profiling Immunoblotting Disease Models, Animal Microscopy, Fluorescence Culture Media, Serum-Free Xenograft Model Antitumor Assays Real-Time Polymerase Chain Reaction Cell Culture Techniques

Phenomena and Processes70

Cell Aging Telomere Apoptosis Aging Cell Proliferation Signal Transduction DNA Damage Biological Processes Telomere Shortening Oxidative Stress Cell Cycle Cell Division Down-Regulation Up-Regulation RNA Interference Gene Expression Regulation Enzyme Activation DNA Fragmentation Time Factors Cell Survival Phenotype Transfection Gene Expression Regulation, Neoplastic Phosphorylation Dose-Response Relationship, Drug Cell Differentiation Cell Cycle Checkpoints Gene Expression Regulation, Plant Cell Death Mutation Longevity Gene Expression Genes, p53 Autophagy Membrane Potential, Mitochondrial Genes, bcl-2 Diploidy Gene Silencing Necrosis Stress, Physiological Base Sequence Protein Binding Genes, ras Transcription, Genetic Promoter Regions, Genetic G1 Phase MAP Kinase Signaling System Gamma Rays Oncogenes Amino Acid Sequence Radiation, Ionizing Drug Resistance, Neoplasm Cell Shape Darkness G2 Phase Cell Cycle Checkpoints Drug Synergism Mitosis Genes, p16 Reproduction Cell Growth Processes Protein Transport Gene Deletion Cytoprotection Genes, Tumor Suppressor G2 Phase Radiation Tolerance Heterochromatin DNA Repair Acetylation Telomere Homeostasis

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Cell Aging Cyclin-Dependent Kinase Inhibitor p16 Telomere Apoptosis Tumor Suppressor Protein p53 beta-Galactosidase Cyclin-Dependent Kinase Inhibitor p21 Aging, Premature Telomerase Aging Cells, Cultured Cell Proliferation Fibroblasts Cell Line, Tumor Signal Transduction DNA Damage Biological Processes Telomere Shortening Reactive Oxygen Species Oxidative Stress Cell Cycle Apoptosis Regulatory Proteins Caspases Retinoblastoma Protein Caspase 3 Proto-Oncogene Proteins c-bcl-2 Cell Line Cell Division Inhibitor of Apoptosis Proteins RNA, Small Interfering Blotting, Western Down-Regulation Endothelial Cells Up-Regulation Plant Leaves RNA Interference Gene Expression Regulation Enzyme Activation DNA Fragmentation Time Factors Flow Cytometry Cell Survival In Situ Nick-End Labeling Phenotype Reverse Transcriptase Polymerase Chain Reaction TOR Serine-Threonine Kinases bcl-2-Associated X Protein Transfection Mice, Inbred C57BL p38 Mitogen-Activated Protein Kinases Mice, Knockout Gene Expression Regulation, Neoplastic DNA-Binding Proteins X-Linked Inhibitor of Apoptosis Protein Phosphorylation Mitochondria Cell Cycle Proteins Dose-Response Relationship, Drug RNA, Messenger Apoptosis Inducing Factor Stem Cells Histones Cell Differentiation CASP8 and FADD-Like Apoptosis Regulating Protein Tumor Cells, Cultured Caspase 9 Caspase Inhibitors Immunohistochemistry Cell Cycle Checkpoints Endothelium, Vascular Caspase 8 Tumor Suppressor Proteins Fas Ligand Protein Cytochromes c Cell Transformation, Neoplastic bcl-X Protein Proto-Oncogene Proteins Annexin A5 Antineoplastic Agents Models, Biological Chlorophyll Biological Markers Gene Expression Regulation, Plant Cell Death Mutation Ethylenes Protein-Serine-Threonine Kinases Atherosclerosis Hydrogen Peroxide Nuclear Proteins Enzyme Inhibitors Cysteine Proteinase Inhibitors Longevity Tumor Suppressor Protein p14ARF Neoplasms Poly(ADP-ribose) Polymerases Transcription Factors Cell Line, Transformed Amino Acid Chloromethyl Ketones Arabidopsis

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