• The cdc25 gene product is a tyrosine phosphatase that acts as an initiator of M-phase in eukaryotic cell cycles by activating p34 cdc2 . (biologists.com)
  • M-phase inducer phosphatase 2 is an enzyme that in humans is encoded by the CDC25B gene. (wikipedia.org)
  • CDC25A is a member of the CDC25 family of phosphatases. (nih.gov)
  • Signals relating to DNA damage and completeness of replication impact on balance of Wee1 (a Cdc2 inhibitory kinase) and Cdc25 activities to delay entry into M phase. (comprehensivephysiology.com)
  • Dephosphorylation of Cdc2 by Cdc25 phosphatase(s) at positions T14 and Y15 leads to generation of active MPF heterodimers ( right ). (comprehensivephysiology.com)
  • PP1 and PP2A inhibitions result in cdc25 activation accompanied by triggered MPF which promotes early mitotic admittance (evaluated in ref.20). (monossabios.com)
  • For their dependency on MPF (cyclin B1-cdk1) the phosphatase inhibitors preferentially induce PCC in G2-stage. (monossabios.com)
  • A subclass of dual specificity phosphatases that play a role in the progression of the CELL CYCLE . (nih.gov)
  • ß-amino-butyric acid (BABA) has been demonstrated to activate an induced resistance response and is a potent inducer of broad-spectrum disease resistance in different plant species. (bvsalud.org)
  • IDE 2 is a cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 223 nM for induction of Sox17 expression in ESCs). (emmx.com)