Induced covalent topoisomerase. Medical search. Frequent questions

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Anatomy21

Tumor Cells, Cultured HeLa Cells Cell Nucleus Cell Line Cell Line, Tumor HL-60 Cells Chromosomes Chromatin KB Cells Eukaryotic Cells Chromosomes, Human Cell Nucleolus Centromere Chromatids Thymus Gland HT29 Cells CHO Cells Chromosome Structures Nucleosomes K562 Cells HCT116 Cells

Organisms18

Escherichia coli Saccharomyces cerevisiae Crithidia fasciculata Leishmania donovani Vaccinia virus Cricetinae Simian virus 40 Cricetulus Molluscum contagiosum virus Drosophila melanogaster Entomopoxvirinae T-Phages Sulfolobus Cattle Streptococcus pneumoniae Yeasts Zygophyllaceae Muntjacs

Diseases12

Leukemia P388 Leukemia L1210 Carcinoma, Small Cell Bloom Syndrome Scleroderma, Systemic Neoplasms Leukemia Vaccinia Leukemia, Promyelocytic, Acute Breast Neoplasms Colonic Neoplasms Translocation, Genetic

Chemicals and Drugs122

Topoisomerase II Inhibitors Topoisomerase I Inhibitors DNA Topoisomerases, Type I DNA Topoisomerases, Type II Topoisomerase Inhibitors DNA Topoisomerase IV Amsacrine Teniposide Camptothecin DNA, Superhelical Etoposide DNA Topoisomerases DNA DNA, Catenated Razoxane Novobiocin Ellipticines Antigens, Neoplasm Intercalating Agents DNA Gyrase DNA-Binding Proteins Topotecan Antineoplastic Agents, Phytogenic Enzyme Inhibitors Podophyllotoxin Antineoplastic Agents DNA, Kinetoplast Aminoacridines Thiobarbiturates Quinolones Anti-Infective Agents Fluoroquinolones Aminocoumarins Isoenzymes Indenes Doxorubicin Aclarubicin Mitoxantrone DNA, Neoplasm Norfloxacin Naphthyridines DNA, Circular RecQ Helicases Nucleic Acid Synthesis Inhibitors Antibiotics, Antineoplastic Naphthoquinones Ciprofloxacin Coumarins Distamycins Acridines Recombinant Proteins DNA Helicases Adenosine Triphosphate DNA, Single-Stranded 4-Quinolones Adenylyl Imidodiphosphate Diminazene Piperazines Chromatin Oligodeoxyribonucleotides Isoquinolines Adenosine Triphosphatases Naphthalimides Carbazoles Aphidicolin Bisbenzimidazole Luteolin DNA, Viral Poly(ADP-ribose) Polymerases Aminacrine Poly Adenosine Diphosphate Ribose Histones DNA, Bacterial Oligonucleotides Myeloid-Lymphoid Leukemia Protein Casein Kinase II Nuclear Proteins Diterpenes Anthracyclines Daunorubicin Alkaloids DNA Adducts RNA, Messenger Cell Cycle Proteins DNA Primers Anthraquinones Benzimidazoles Chromomycins Tumor Suppressor Protein p53 Imides Glucosides Recombinant Fusion Proteins Phosphoric Diester Hydrolases Hexylresorcinol DNA, Fungal Streptonigrin Magnesium Oxolinic Acid Sulfanilamides DNA, Cruciform Xanthones Anti-Bacterial Agents Protein-Serine-Threonine Kinases Ofloxacin Small Ubiquitin-Related Modifier Proteins Nalidixic Acid Indoles Neoplasm Proteins P-Glycoprotein Cross-Linking Reagents Nucleoside Diphosphate Sugars Nucleosomes Cisplatin Chromosomal Proteins, Non-Histone DNA Ligases Quinolines Benzodioxoles Ataxia Telangiectasia Mutated Proteins Triterpenes Cell Extracts Archaeal Proteins Bacterial Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Drug Screening Assays, Antitumor Cloning, Molecular Models, Molecular Electrophoresis, Agar Gel Inhibitory Concentration 50 Restriction Mapping Electrophoresis, Polyacrylamide Gel Blotting, Western Amino Acid Substitution Microbial Sensitivity Tests Mutagenesis, Site-Directed Polymerase Chain Reaction Blotting, Southern Comet Assay Tumor Stem Cell Assay Models, Biological Transfection Genetic Complementation Test Microscopy, Fluorescence DNA Footprinting Enzyme Stability

Phenomena and Processes76

DNA, Superhelical DNA Cleavage DNA, Catenated DNA Damage Base Sequence Nucleic Acid Conformation Drug Resistance Plasmids Catalysis Mutation Substrate Specificity DNA Replication Cell Cycle Binding Sites Kinetics Amino Acid Sequence Drug Resistance, Neoplasm DNA, Circular Mitosis Cell Survival DNA Repair Protein Binding Structure-Activity Relationship Hydrolysis DNA, Single-Stranded Chromosomes Apoptosis Chromatin DNA Breaks Recombination, Genetic Transcription, Genetic Dose-Response Relationship, Drug G2 Phase DNA Breaks, Double-Stranded Inhibitory Concentration 50 Molecular Structure Cell Division Protein Structure, Tertiary Sequence Homology, Amino Acid Chromosome Segregation Molecular Weight Chromosomes, Human DNA Adducts Protein Conformation Drug Synergism Phosphorylation DNA Fragmentation Amino Acid Substitution Drug Resistance, Bacterial Drug Resistance, Microbial Time Factors Centromere Gene Expression Regulation, Enzymologic Mutagenesis Chromatids Point Mutation S Phase Gene Expression Catalytic Domain DNA, Cruciform Gene Deletion Drug Resistance, Multiple Metaphase Promoter Regions, Genetic Enzyme Activation Sister Chromatid Exchange Phenotype Anaphase Genes Chromosome Structures Nucleosomes Sequence Deletion Transfection Translocation, Genetic Enzyme Stability Genes, Bacterial

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science

Topoisomerase II Inhibitors Topoisomerase I Inhibitors DNA Topoisomerases, Type I DNA Topoisomerases, Type II Topoisomerase Inhibitors DNA Topoisomerase IV Amsacrine Teniposide Camptothecin DNA, Superhelical Etoposide DNA Topoisomerases DNA DNA Cleavage DNA, Catenated Razoxane Novobiocin Ellipticines Antigens, Neoplasm Intercalating Agents DNA Damage DNA Gyrase DNA-Binding Proteins Topotecan Antineoplastic Agents, Phytogenic Enzyme Inhibitors Podophyllotoxin Molecular Sequence Data Antineoplastic Agents Base Sequence Nucleic Acid Conformation DNA, Kinetoplast Aminoacridines Thiobarbiturates Quinolones Drug Resistance Tumor Cells, Cultured Plasmids Anti-Infective Agents Catalysis Fluoroquinolones Aminocoumarins Mutation Substrate Specificity Escherichia coli DNA Replication Drug Screening Assays, Antitumor Isoenzymes Indenes Leukemia P388 Doxorubicin Saccharomyces cerevisiae Crithidia fasciculata Aclarubicin Cell Cycle Binding Sites Mitoxantrone Kinetics Amino Acid Sequence DNA, Neoplasm Norfloxacin HeLa Cells Cell Nucleus Naphthyridines Drug Resistance, Neoplasm DNA, Circular RecQ Helicases Nucleic Acid Synthesis Inhibitors Leukemia L1210 Mitosis Leishmania donovani Cell Line Cell Survival Antibiotics, Antineoplastic DNA Repair Cell Line, Tumor Cloning, Molecular Naphthoquinones Ciprofloxacin Coumarins Vaccinia virus Distamycins Protein Binding Models, Molecular Electrophoresis, Agar Gel Structure-Activity Relationship Acridines Recombinant Proteins HL-60 Cells DNA Helicases Adenosine Triphosphate Hydrolysis DNA, Single-Stranded 4-Quinolones Adenylyl Imidodiphosphate Chromosomes Diminazene Piperazines Apoptosis Chromatin

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