K562 CellsApoptosisApoptosis Regulatory ProteinsCaspasesCaspase 3Proto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsDNA FragmentationIn Situ Nick-End Labelingbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinCell Line, TumorCell SurvivalH(+)-K(+)-Exchanging ATPaseApoptosis Inducing FactorCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Caspase InhibitorsCells, CulturedSignal TransductionCaspase 8MitochondriaFas Ligand ProteinTumor Suppressor Protein p53Enzyme ActivationVitamin KCytochromes cCell LineTumor Cells, Culturedbcl-X ProteinCell ProliferationAnnexin A5Enzyme InhibitorsProto-Oncogene ProteinsBlotting, WesternAmino Acid Chloromethyl KetonesFlow CytometryCysteine Proteinase InhibitorsCell CycleAntineoplastic AgentsVitamin K 1Poly(ADP-ribose) PolymerasesDose-Response Relationship, DrugReactive Oxygen SpeciesCell DivisionRNA, Small InterferingProto-Oncogene Proteins c-aktTNF-Related Apoptosis-Inducing LigandDown-RegulationJurkat CellsTransfectionTime FactorsCaspase 7Membrane Potential, MitochondrialHL-60 CellsTumor Necrosis Factor-alphaCell DeathUp-RegulationGenes, bcl-2Phosphatidylinositol 3-KinasesMice, Inbred C57BLPhosphorylationbcl-2 Homologous Antagonist-Killer ProteinNF-kappa BMembrane GlycoproteinsNecrosisCytochrome c GroupDNA DamageMyeloid Cell Leukemia Sequence 1 ProteinBH3 Interacting Domain Death Agonist ProteinRNA, MessengerStaurosporineGene Expression RegulationHeLa CellsReverse Transcriptase Polymerase Chain Reactionbcl-Associated Death ProteinImmunohistochemistryModels, BiologicalGene Expression Regulation, NeoplasticDrug SynergismAntineoplastic Agents, PhytogenicRats, Sprague-DawleyGene ExpressionOxidative StressPotassium ChannelsNeoplasm ProteinsCeramidesRNA InterferenceReceptors, TNF-Related Apoptosis-Inducing LigandProtein-Serine-Threonine KinasesCarrier ProteinsMitogen-Activated Protein KinasesMice, KnockoutRecombinant ProteinsCysteine EndopeptidasesCaspase 2Epithelial CellsFas-Associated Death Domain ProteinApoptotic Protease-Activating Factor 1Base Sequence