• Certain viruses, specifically the AD-36 adenovirus, have been shown to increase body fat in laboratory animals. (wikipedia.org)
  • TLRs activate viral responses by recognizing pathogenic microorganisms such as viruses, bacteria, and mycoplasmas to release inflammatory cytokines [ 10 ]. (hindawi.com)
  • Tumors and their surroundings contain complex mixtures of cancer cells, normal cells, and a variety of microorganisms such as bacteria and viruses," says the study's senior author, Matthew Meyerson, MD, PhD, of Dana-Farber and the Broad Institute. (health.am)
  • Because they contain living bacteria or viruses, live-attenuated vaccines can provide enduring protection with only two doses. (cdc.gov)
  • With the exception of some spore-forming bacteria and envelope-lacking viruses, ethanol shows a broad antibacterial and antiviral spectrum. (medsci.org)
  • However, the extensive use, misuse and overuse of antimicrobials in both human and animal health1 have increasingly raised levels of antimicrobial resistance in a wide range of pathogens (bacteria, viruses, fungi and parasites) - in all countries and patients of all age groups. (who.int)
  • Regular procedures such as bathing and cleaning of their teeth are very much necessary to prevent the pets from the attack of infectious bacteria, viruses, and other diseases. (powershow.com)
  • In many species of animals, 2,3,7,8-TCDD weakens the immune system and causes a decrease in the system's ability to fight bacteria and viruses. (cdc.gov)
  • Such invaders include Microorganisms (commonly called germs, such as bacteria, viruses, and fungi) Parasites. (msdmanuals.com)
  • Bacteria and viruses were not detected, and all toxicants were either not detected or within acceptable range. (cdc.gov)
  • WHEN WE ARRIVE IN a new environment that contains unfamiliar pathogens i.e. disease-inducing bacteria, parasites, viruses or fungi, we are more susceptible to illness. (lu.se)
  • Researchers found that the increased presence of a protein called NLRP1, which is responsible for sensing infection, was correlated with fewer good bacteria and anti-inflammatory molecules in the gut, leading to higher levels of inflammation. (nutritionaloutlook.com)
  • Researchers also found that the presence of good bacteria produces a molecule called butyrate, which is important to keeping levels of inflammation down. (nutritionaloutlook.com)
  • By stopping overproduction of NLRP1 or IL-18 in patients with IBD, we may be able boost the number of good bacteria and anti-inflammatory properties in the gut and help to prevent or fight the damaging effects of too much inflammation. (nutritionaloutlook.com)
  • According to Greger, meat-induced inflammation is an immune response. (bewellbuzz.com)
  • After exposure, parameters of lung injury, (lactate dehydrogenase and albumin) and inflammation (PMN influx) were measured in the bronchoalveolar lavage fluid recovered from each animal. (cdc.gov)
  • OBJECTIVE- Hyperglycemia-induced inflammation is central in diabetes complications, and monocytes are important in orchestrating these effects. (diabetesjournals.org)
  • In the current study, mice infected with the M pneumoniae bacterium were treated daily with a placebo, an antibiotic, a steroid, or a combination of the antibiotic and steroid in order to investigate the effect on M pneumoniae -induced airway inflammation. (news-medical.net)
  • Lacking this bacteria might encourage the immune system to overreact to harmless microbes in people with MS, causing harmful inflammation. (genomeweb.com)
  • Here we show that a rosette inducing factor (RIF-1) produced by A. machipongonensis belongs to the small class of sulfonolipids, obscure relatives of the better known sphingolipids that play important roles in signal transmission in plants, animals and fungi. (phys.org)
  • However, bacteria and fungi on the skin can wreak havoc on the culturing processes used to grow cells in labs, making the process tricky to successfully carry out. (livescience.com)
  • NEI just received FDA approval to begin the first-ever trial using tissue derived from patient-derived human induced pluripotent stem cells (hIPSCs), reprogrammed adult cells that can be converted into other cell types. (nih.gov)
  • Mature cells can be made or induced to become immature cells, known as pluripotent stem cells , which have the ability to become any tissue in the body and potentially can replace cells destroyed by disease or injury. (livescience.com)
  • Cadaver-collected fibroblasts can be reprogrammed into induced pluripotent stem cells using chemicals known as growth factors that are linked with stem cell activity. (livescience.com)
  • Now scientists have taken fibroblasts from the scalps and the brain linings of 146 human brain donors and grown induced pluripotent stem cells from them as well. (livescience.com)
  • Successfully reprogramming induced pluripotent stem cells so they behave like the cells they are meant to replace means that samples of the mimicked cells must be present for comparison. (livescience.com)
  • Studying how induced pluripotent stem cells develop into various tissues could also shed light on disorders that are due to malfunctions in development. (livescience.com)
  • A biopharmaceutical (biological or biologic), which consists of sugars, proteins, nucleic acids, living cells, or tissues, is a medicinal product manufactured in extracted or semi-synthesized from biological sources like humans, animals, or microorganisms. (intechopen.com)
  • Transgenic organisms, especially plants, animals, or microorganisms that have been genetically modified, are potentially used to produce biopharmaceuticals. (intechopen.com)
  • "(The bacteria) induced some cognitive deficits on its own," Noble said. (fabresearch.org)
  • In addition to neurobehavioral and cognitive deficits, TBI induces other maladaptive behaviors, such as agitation and aggression, which must be managed for safe, accurate assessment and effective treatment of the patient. (bvsalud.org)
  • TLR9 is a member of the TLR family whose function is triggered by the unmethylated CpG motif of microbial DNA, which initiates the immune response by inducing cytokines and many molecules [ 11 ]. (hindawi.com)
  • Animal studies suggest these compounds can affect levels of brain neurotransmitters (the molecules of emotion ) as well as change the brain's ability to repair itself. (psychologytoday.com)
  • The gut microbiota functionally influences host genetic events mainly through specific media molecules produced by the bacteria ( 10 - 13 ). (frontiersin.org)
  • The findings have added importance because researchers have long thought that choanoflagellates are animals closest relative, which means that it's possible that bacteria and the molecules they produce, could conceivably be part of the reason that single celled organisms first began to form colonies, leading eventually to multi-celled beings that evolved over time into all of the animals that are alive today. (phys.org)
  • Bacterially-produced small molecules exert profound influences on animal health, morphogenesis, and evolution through poorly understood mechanisms. (phys.org)
  • Modeling microbiome connections to organismal protein homeostasis (proteostasis) has been successful in the nematode C. elegans, where ingestion of human pathogenic bacteria has been demonstrated to cause proteostatic collapse. (plos.org)
  • Phages for Global Health (PGH) is training scientists in these regions to isolate relevant therapeutic phages for pathogenic bacteria within their locality, and thus contributing to making phage technology universally available. (bvsalud.org)
  • Notably, different strains of gut bacteria can have profoundly different regulatory effects on immune system function. (frontiersin.org)
  • Some strains of oral bacteria associated with periodontal disease have been shown to accelerate atherosclerosis and induce arterial lesions in animal models. (colgateprofessional.com)
  • That led to a search through some sixty strains of bacteria to determine which had caused the change. (phys.org)
  • However, while many insights into the control of obesity have come from experiments since its introduction in 1949, the use of animal models does restrict our ability to extrapolate findings to humans. (wikipedia.org)
  • Obesity is affected by "environmental, biological, and psychosocial pressures", therefore it is understandable that several limitations are established when translating results between the results of a diet induced obesity model in a lab and humans. (wikipedia.org)
  • For positive controls, 5 L of 0.001 pg/L in humans and can cause similar disease manifestations in of B. henselae DNA (equivalent to 2.5 genome copies) animals ( 1 , 2 ). (cdc.gov)
  • This was primarily done to reduce the antibiotic resistance among pathogens in farm animals, thereby reducing the risk of its transmission to humans through food products. (marketsandmarkets.com)
  • Humans are one of the most complex microbial ecosystems on the planet, hosting over 100 trillion bacteria, mainly in the distal gut ( 5 ). (frontiersin.org)
  • Microbiological studies of the sanitary and health status of psittacine birds that will be reintroduced is important in evaluating whether these animals act as carriers of pathogenic agents to other animals and humans. (scielo.br)
  • All these agents are potentially pathogenic for parrots and can cause systemic infections in other animals and humans. (scielo.br)
  • It is important for us to be informed and to be up to date with genetically engineered food, the health risks it poses to humans, animals, birds, insects, and the damage it causes to our environment also the threats it poses to farmers. (jesus-is-savior.com)
  • 1] Animal experimentation is going on all over the world the genes from chicken, cows, rats and humans have been engineered into commercial fish species in order to increase the growth rates- GM salmon, for instance, have been engineered to reach six times their natural size. (jesus-is-savior.com)
  • In contrast to other antiseptics with efficacy against spore-forming bacteria, PVP-I shows low toxicity in humans. (medsci.org)
  • Humans acquire EHEC by ingesting contaminated food or water, or through contact with animals or their environment. (sciencedaily.com)
  • If not handled adequately, these bacteria can be transferred to humans as well and compromise their health too. (powershow.com)
  • Some conventional biopharmaceuticals are extracted from animals or humans particularly. (intechopen.com)
  • A study in mice and humans suggests that bacteria in the gut can influence the structure of the brain s blood vessels, and may be responsible for producing malformations that can lead to stroke or epilepsy. (mybestlife.com)
  • Toxins are substances created by plants and animals that are poisonous (toxic) to humans. (medlineplus.gov)
  • Most toxins that cause problems in humans come from germs such as bacteria. (medlineplus.gov)
  • The gastrointestinal microbiome of psittacine free-living birds has been poorly understood, but the most of reports shows that the normal psittacine bird microbiota is composed by Gram-positive facultative bacteria, that is, aerobic and anaerobic, and producers of lactic acid ( Gerlach, 1994 GERLACH, H., 1994. (scielo.br)
  • The team decided to perform fecal transplants on mice with an experimentally induced form of MS. They discovered that swapping the mice's microbiomes with those of MS patients caused the animals to lose key immune-regulatory cells and instead develop more severe neurodegeneration, indicating that the microbiome alone could affect the progression of MS. (genomeweb.com)
  • The researchers explored changes to the body s bacteria (microbiome) in two ways. (mybestlife.com)
  • Researchers have found that a bacteria called Pseudoalteromonas luteoviolacea must be present for H. elegans to metamorphose. (livescience.com)
  • he researchers have now identified that the bacteria produces syringelike structures similar to virus tails that appear to be the key to the bacteria's role in the tubeworm metamorphosis. (livescience.com)
  • Researchers from the University of Rochester Medical Center in New York set out to explore what links there might be between diet, obesity, gut bacteria, and osteoarthritis. (medicalnewstoday.com)
  • To induce osteoarthritis, the researchers tore the animals' menisci, or the cushion of cartilage between the shin and thigh bones. (medicalnewstoday.com)
  • Researchers used mice with deficient levels of NLRP1 and then induced colitis. (nutritionaloutlook.com)
  • Too much NLRP1 leads to an overproduction of a signaling molecule called IL-18 that tells the body to mount a protective response against the threat of colonization by bad bacteria-but as a consequence the good bacteria and their anti-inflammatory products are also lost," explains Associate Professor Seth Masters, one of the lead researchers, in a press release . (nutritionaloutlook.com)
  • In another study published in the same issue of PNAS, a team led by researchers from the Max Planck Institute of Neurobiology with contributions from Cekanaviciute and UCSF colleague Sergio Baranzini compared the gut microbiota of 34 monozygotic twin pairs discordant for MS. While they found no major differences in the overall human microbial composition, the researchers saw a significant increase in bacteria such as A. muciniphila. (genomeweb.com)
  • For example, the researchers found that at least one MS-associated bacteria could confuse the immune system into attacking myelin as well as the bacteria. (genomeweb.com)
  • The researchers were studying a well-established mouse model that forms a significant number of CCMs following the injection of a drug to induce gene deletion. (mybestlife.com)
  • Phys.org) -- Researchers working at a lab at Berkeley University, led by Nicole King, have uncovered the first example of a kind of bacteria that causes a single celled organism to form a colony, a finding that has implications for researchers looking into the origins of multi-celled organisms in general. (phys.org)
  • We found that RSV attenuated trimethylamine-N-oxide (TMAO)-induced AS in ApoE(-/-) mice. (nih.gov)
  • For comparison, mice with higher expression of NLRP1 were also induced with colitis. (nutritionaloutlook.com)
  • NC/Nga mice were subcutaneously injected with mite allergen (Dp) to induce AD-like skin lesions (ADSLs), and an application of 0.2% (w/v) benzalkonium chloride (BZK), 10% (w/v) povidone-iodine (PVP-I), 80% (v/v) ethanol (Et-OH), or 0.5% (v/v) chlorhexidine gluconate (CHG) was applied to the ear envelope. (medsci.org)
  • A team of scientists at the University of Pennsylvania investigated the mechanisms that cause CCM lesions to form in genetically engineered mice and discovered an unexpected link to bacteria in the gut. (mybestlife.com)
  • The mice that formed CCMs also had abscesses in their spleens, which meant that the bacteria had entered the bloodstream from the initial abscess site, said Tang. (mybestlife.com)
  • [13] The biofilm bacteria can share nutrients and are sheltered from harmful factors in the environment, such as desiccation, antibiotics, and a host body's immune system. (wikipedia.org)
  • A biofilm usually begins to form when a free-swimming bacterium attaches to a surface. (wikipedia.org)
  • They can be found very early in Earth's fossil records (about 3.25 billion years ago) as both Archaea and Bacteria, and commonly protect prokaryotic cells by providing them with homeostasis, encouraging the development of complex interactions between the cells in the biofilm. (wikipedia.org)
  • [8] [5] The first colonist bacteria of a biofilm may adhere to the surface initially by the weak van der Waals forces and hydrophobic effects. (wikipedia.org)
  • In this report, we show that infection with influenza A virus and treatment with the resulting host signals (febrile-range temperatures, norepinephrine, extracytoplasmic ATP, and increased nutrient availability) induce the release of bacteria from biofilms in a newly developed biofilm model on live epithelial cells both in vitro and during in vivo colonization. (lu.se)
  • These dispersed bacteria have distinct phenotypic properties different from those of both biofilm and broth-grown, planktonic bacteria, with the dispersed population showing differential virulence gene expression characteristics resulting in a significantly increased ability to disseminate and cause infection of otherwise sterile sites, such as the middle ear, lungs, and bloodstream. (lu.se)
  • In this study, we determined that changes in the nasopharyngeal environment result in the release of bacteria from colonizing biofilms with a gene expression and virulence phenotype different not only from that of colonizing biofilm bacteria but also from that of the broth-grown planktonic bacteria commonly used for pathogenesis studies. (lu.se)
  • The examination of coal-tar coated water mains revealed that in addition to the protective effect of a biofilm a vast amount of the PAHs was adsorbed on particles embedded in the biofilm, e.g. from the iron oxidising bacteria Gallionella. (who.int)
  • Alterations in the composition of intestinal bacteria in individuals with preclinical and established RA suggest a vital role of the gut microbiota in immune dysfunction characteristic of RA. (frontiersin.org)
  • After ingesting any sort of animal product, the bloodstream is filled with endotoxins, a type of bacterial toxin. (bewellbuzz.com)
  • The bacteria begin to produce Shiga toxin when a virus present in the EHEC genome is induced to leave its dormant state and begin to replicate, a process promoted by many antibiotics. (sciencedaily.com)
  • Until now, it was generally believed that extensive virus replication was necessary for the bacteria to produce sufficient toxin to cause disease. (sciencedaily.com)
  • One way a diet rich in animal-sourced foods like meat, eggs, and cheese may contribute to heart disease, stroke, kidney failure, and death is through the production of toxin called TMAO. (nutritionfacts.org)
  • For example, the symptoms of cholera are caused by a toxin made by cholera bacteria. (medlineplus.gov)
  • Toxin- and drug-induced liver disease. (medlineplus.gov)
  • A new animal study shows that the immune system helps maintain good gut bacteria in addition to defending against bad bacteria. (nutritionaloutlook.com)
  • Gut-barrier disruption leads to translocation of dangerous intraluminal components, such as bacteria and their components, into the gut wall and, most importantly, exposes the immune system to them. (medscape.com)
  • MHC (Major Histocompatibility Complex) is a complex of proteins that constitutes an important part of the immune system, helping to reveal the presence of bacteria or a virus in cells, for example. (lu.se)
  • Swine pneumonia, commonly known as swine pasteurellosis, is a contagious disease induced by Pasteurella multocida infection which is divided into chronic type, acute type, and most acute type according to clinical manifestations and the course of the disease [ 1 ]. (hindawi.com)
  • Vitamin K2 (VK2) is commonly produced by gut bacteria and is fat-soluble, allowing it to be easily transferred into the host intestinal cells ( 14 ). (frontiersin.org)
  • Others have claimed that a certain bacteria (Spiroplasma mirum) is capable of producing lesions of spongiform encephalopathy. (usda.gov)
  • They did not show clinical neurologic signs, their brains did not have lesions of spongiform encephalopathy and their tissues were negative for the bacteria. (usda.gov)
  • When bacteria were eliminated the number of lesions was greatly diminished. (mybestlife.com)
  • This suggested a connection between the spread of a specific type of bacteria through the bloodstream and the formation of these blood vascular lesions in the brain. (mybestlife.com)
  • Our next question was whether we could prevent lesions by changing the bacteria in the body. (mybestlife.com)
  • 1 blood Bacteria species and strain identifi cation was performed by sample for 57 feral pigs. (cdc.gov)
  • Some gut bacteria species can induce autoimmunity in genetically predisposed animal models ( 6 , 7 ). (frontiersin.org)
  • High glucose has been shown to induce inflammatory cytokines, chemokines, p38 mitogen-activated protein kinase, reactive oxygen species (ROS), protein kinase C (PKC), and nuclear factor-κB (NF-κB) activity in both clinical and experimental systems ( 7 - 12 ). (diabetesjournals.org)
  • They identified distinct species of bacteria that were in higher concentrations in people with MS than in the general population. (genomeweb.com)
  • In certain animal species, 2,3,7,8-TCDD is especially harmful and can cause death after a single exposure. (cdc.gov)
  • Some animal species exposed to CDDs during pregnancy had miscarriages and the offspring of animals exposed to 2,3,7,8-TCDD during pregnancy often had severe birth defects including skeletal deformities, kidney defects, and weakened immune responses. (cdc.gov)
  • The diet-induced obesity model (DIO model) is an animal model used to study obesity using animals that have obesity caused by being fed high-fat or high-density diets. (wikipedia.org)
  • Indeed, when you follow kidney patients over time, and assess their freedom from death, those with higher TMAO-even controlling for kidney function-lived significantly shorter lives, indicating this is a diet-induced mechanism for progressive kidney scarring and dysfunction, strongly implying "the need to focus preventi[ti]ve efforts on dietary [modification]. (nutritionfacts.org)
  • While the relationship - if any - between colorectal cancer and Fusobacterium is unclear, there are intriguing hints that the bacterium may play a role in the cancer, says Meyerson, who is co-director of the Center for Cancer Genome Discovery at Dana-Farber and a professor of pathology at Harvard Medical School. (health.am)
  • The 16S rDNA is present in scattered form in the entire genome of bacteria. (ispub.com)
  • Atypical bacteria, Chlamydia pneumoniae , and Mycoplasma pneumoniae infections may precede asthma onset or exacerbate asthma, 3 and these bacteria might be involved in chronic asthma. (bmj.com)
  • Pneumonia caused by the Mycoplasma pneumoniae bacterium is generally a less severe form of the disease that can occur in any age group. (news-medical.net)
  • An FXR antagonist had the same effect on FGF15 and CYP7A1 expression as RSV, while an FXR agonist abolished RSV-induced alterations in FGF15 and CYP7A1 expression. (nih.gov)
  • Exposure to high concentrations of CDDs may induce long-term alterations in glucose metabolism and subtle changes in hormonal levels. (cdc.gov)
  • their bowels were overrun with pro-inflammatory bacteria and had a distinct lack of healthy, probiotic bacteria, such as Bifidobacteria . (medicalnewstoday.com)
  • This subtle but important change in diet promoted the growth of healthy bacteria and produced a marked reduction in pro-inflammatory bacteria. (medicalnewstoday.com)
  • Additional studies revealed that PKC-α, PKC-δ, and p47Phox knockdown significantly abrogated high-glucose-induced NF-κB activation and inflammatory cytokine secretion. (diabetesjournals.org)
  • BZK induced a significant increase in the severity of the clinical score, infiltration of inflammatory cells, local expression of inflammatory cytokines in subcutaneous tissue, and total serum immunoglobulin (Ig) E. PVP-I increased the clinical score, number of mast cells, and production of inflammatory cytokines, and total serum IgE. (medsci.org)
  • In this study, we found that VK2 can extend the lifespan of C. elegans and improve the resistance to pathogen infection, heat stress and H 2 O 2 -induced inner oxidative stress. (frontiersin.org)
  • We show that these interkingdom signals are recognized by bacteria and are induced by influenza virus infection, which is epidemiologically strongly associated with transition to secondary pneumococcal disease. (lu.se)
  • Importantly, EGFR inhibition suppressed TGF-beta expression, and an inhibitory thrombospondin-1 (Tsp1)-based peptide inhibited chlamydia-induced EMT, revealing a major source of active TGF-betaduring infection. (cdc.gov)
  • Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a faster and more accurate method to identify bacteria than conventional microbiology methods. (scielo.br)
  • In conclusion, RSV attenuated TMAO-induced AS by decreasing TMAO levels and increasing hepatic BA neosynthesis via gut microbiota remodeling, and the BA neosynthesis was partially mediated through the enterohepatic FXR-FGF15 axis. (nih.gov)
  • The gut microbiota plays a key role in the pathophysiology of TMAO-induced AS. (nih.gov)
  • The current study showed that RSV attenuated TMAO-induced AS by decreasing TMAO levels and increasing hepatic BA neosynthesis via gut microbiota remodeling. (nih.gov)
  • Literature data on gut microbiota show that all dietary changes can induce the alteration of gut microbiota composition. (karger.com)
  • VK2 is mainly produced by gut bacteria, suggesting that VK2 might facilitate communication between the gut microbiota and the host intestinal cells to influence fat metabolism. (frontiersin.org)
  • The intestinal microbiota impact obesity, fatty liver diseases, and weight loss by way of the ability to induce the expression of genes related to lipid metabolism ( 6 , 10 ). (frontiersin.org)
  • NEW YORK (GenomeWeb) - A pair of newly published studies has established a potential role for specific gut bacteria in the progression of multiple sclerosis (MS), suggesting therapeutic targeting of the microbiota as a potential treatment for the disease. (genomeweb.com)
  • The work importantly also identifies specific host factors responsible for the release of bacteria and their changed phenotype. (lu.se)
  • Supporting this possibility, they found that similar memory deficits were observed even when the bacteria, called Parabacteroides, were experimentally enriched in the guts of animals that had never consumed sugar. (fabresearch.org)
  • Scientists at Dana-Farber Cancer Institute and the Broad Institute have found strikingly high levels of a bacterium in colorectal cancers, a sign that it might contribute to the disease and potentially be a key to diagnosing, preventing, and treating it. (health.am)
  • We describe structures of apo and c-di-GMP-bound GlgX and, strikingly, their comparison shows c-di-GMP induces long-range conformational changes, reorganizing the catalytic pocket to an active state. (nih.gov)
  • That led them to a lipid molecule they have named Rosette-Inducing Factor 1 (RIF-1). (phys.org)
  • 0.05) decrease in high-glucose-induced NF-κB activity, suggesting an additive effect. (diabetesjournals.org)
  • Small inhibitory RNA to p47Phox in THP-1 cells abrogated high-glucose-induced TLR2 and TLR4 expression. (diabetesjournals.org)
  • CONCLUSIONS- Collectively, these data suggest that high glucose induces TLR2 and -4 expression via PKC-α and PKC-δ, respectively, by stimulating NADPH oxidase in human monocytes. (diabetesjournals.org)
  • Glycogen is an important glucose storage compound that enables animals to cope with starvation and stress. (nih.gov)
  • The team then shifted to the much more challenging task of investigating how these differences in gut bacteria could influence the immune system's attack on myelin in MS. (genomeweb.com)
  • In this paper, we aimed to study the specific mechanism of swine pneumonia induced by HD-13. (hindawi.com)
  • Although premature infants have partial lactase deficiency because of intestinal immaturity, enzyme expression can be induced by lactose ingestion. (medscape.com)
  • Irritant-induced asthma refers to asthma that occurs following exposure to respiratory irritants at work. (msdmanuals.com)
  • Improvement of lactose digestion in a previously intolerant child or adult is caused by growth of lactose-digesting bacteria rather than an induction in activity of the lactase enzyme because lactase is a noninducible enzyme. (medscape.com)
  • With increasing travel and trade in food, drug resistance can spread rapidly, as exemplified by the resistance-inducing enzyme metallo-beta-lactamase-1 (NDM-1), which confers resistance to carbapenems, an important group of antibiotics: it was first detected in one country in 2008 but has now been found on all continents. (who.int)
  • Here we show that c-di-GMP also binds the glycogen-debranching-enzyme, GlgX, uncovering a direct link between c-di-GMP and glycogen metabolism in bacteria. (nih.gov)
  • The authors believe future research will center on figuring out how the bacteria influence the development and progression of MS. (genomeweb.com)
  • There is evidence that pathogenic oral bacteria are present in atherothrombotic tissues, where blood has clotted at the site of an arterial plaque. (colgateprofessional.com)
  • These animals can then be used to study in vivo obesity, obesity's comorbidities, and other related diseases. (wikipedia.org)
  • Social and environmental determinants may also induce the onset of obesity. (wikipedia.org)
  • "Early life sugar increased Parabacteroides levels, and the higher the levels of Parabacteroides, the worse the animals did in the task," said Emily Noble, assistant professor in the UGA College of Family and Consumer Sciences who served as first author on the paper. (fabresearch.org)
  • Parabacteroides distasonis , a bacteria found at lower than usual levels in MS patients, triggered an immune-regulatory response as well. (genomeweb.com)
  • Next the team tore apart the bacteria trying to figure out what unique property it held that caused choanoflagellates to form into a colony. (phys.org)
  • A new study, published this week in the journal JCI Insight , looked at a more intriguing mechanism that might link these two conditions: gut bacteria. (medicalnewstoday.com)
  • Additionally, RSV-induced inhibition of TMAO-caused AS was also markedly abolished by antibiotics. (nih.gov)
  • With the help of certain gut bacteria, the choline and carnitine found concentrated in animal products can get converted into TMAO. (nutritionfacts.org)
  • Remember, you can feed a vegan a steak, and they still don't really make any TMAO, because they haven't been fostering the carnitine-eating bacteria in their gut. (nutritionfacts.org)
  • It teeters on the edge of incrementalism given the wealth of reports preceeding it on the topic, but breaks new ground with the butyrate experiments that clearly tie pathogen-induced proteostasis defects with previous findings. (plos.org)
  • Efficacious stem cell-based therapies for traumatic brain injury (TBI) depend on successful delivery, migration, and engraftment of stem cells to induce neuroprotection. (bvsalud.org)
  • We found that the bacteria alone was sufficient to impair memory in the same way as sugar, but it also impaired other types of memory functions as well. (fabresearch.org)
  • based on sufficient evidence in experimental animals and inadequate evidence from epidemiological studies. (who.int)
  • CDD concentrations may build up in the food chain, resulting in measurable levels in animals. (cdc.gov)
  • Rush also prescribed drugs, like mercury, arsenic, and strychnine-now known to be poisonous-to induce vomiting and diarrhea and suggested fasting for two or three days. (amenclinics.com)
  • In vitro and animal studies suggest that atypical agents play a role in the pathogenesis of the disease. (bmj.com)
  • There is lack of consideration for a large segment of the population that has ethical or religious beliefs that classify genetically engineered plants carrying animal or human genes as being totally unacceptable as foods. (jesus-is-savior.com)
  • Some scientists believe that human adult lactase polymorphism evolved in the Neolithic period, after animal milk became available for the nutrition of older children and adults. (medscape.com)
  • Results of this study indicate that Spiroplasma mirum does not induce TSE-like disease in raccoons. (usda.gov)
  • This study provides a prototypical example of bacterial sulfonolipids triggering eukaryotic morphogenesis and suggests molecular mechanisms through which bacteria may have contributed to the evolution of animals. (phys.org)
  • These ribosomal sequences was functional for the phylogenetic analysis and molecular taxonomic of any bacteria. (ispub.com)
  • AGI has launched three key research consortia, to image individual cells in the eye as they respond to light, to identify factors that control cell regeneration in the visual system, and to develop animal models to test regenerative therapies. (nih.gov)
  • In addition, analysis on culture dependent and culture independent bacteria were done, which might play a vital role in the degradation of the non-degradable compounds. (ispub.com)
  • As a cationic detergent in the family of quaternary ammonium compounds, benzalkonium chloride (BZK) shows strong antiseptic activity against both gram-positive and -negative bacteria. (medsci.org)
  • Low-cost laser-induced graphene (LIG) offers a promising alternative to commercially available graphene for next-generation wearable and portable devices, thanks to its remarkable specific surface area, excellent mechanical flexibility, and exceptional electrical properties. (lifeboat.com)
  • Risk of developing sensitizer-induced asthma varies by occupation and the specific substances encountered in the workplace. (msdmanuals.com)
  • Using an EHEC disease mouse model, the authors show that an inducing signal needed to begin viral replication is essential for lethal disease. (sciencedaily.com)