Induce acute and chronic. Medical search. Frequent questions

Chronic obstructive pulmonary disease (COPD) is a leading cause of disability and death world-wide, where chronic inflammation accelerates lung function decline. (frontiersin.org)
Pathological inflammation is worsened by chronic bacterial lung infections and susceptibility to recurrent acute exacerbations of COPD (AECOPD), typically caused by viral and/or bacterial respiratory pathogens. (frontiersin.org)
Here, we review emerging mechanisms into why COPD patients are susceptible to chronic bacterial infections and highlight dysregulated inflammation and production of reactive oxygen species (ROS) as central causes. (frontiersin.org)
COPD is characterized as a chronic inflammatory condition due to the persistent accumulation of innate and adaptive immune cells in the airways along with increased systemic inflammation ( 3 ). (frontiersin.org)
Although inflammation is an important process to combat infections and to accelerate wound healing, overactivation of the immune system can lead to detrimental effects such as chronic skin inflammation 12 . (nature.com)
Early treatment is essential, as chronic bladder inflammation can lead to squamous metaplasia and squamous cell carcinoma. (appliedradiology.com)
After exposure to cocaine adulterated with the immunomodulator levasimole, a 48-year-old patient developed acute inflammation and ulcers that were expected to require long-term home nursing care. (bcmj.org)
The acute inflammation was resolved, but her chronic ulcers were expected to cause further debilitating pain and require long-term home nursing care. (bcmj.org)
Pulmonary exposure to certain forms of carbon nanotube s (CNT) induces fibrosing lesions in the lungs that manifest an acute inflammation followed by chronic interstitial fibrosis. (cdc.gov)
Anti-inflammatory activity was assessed using the carrageenan test, and both TDT1 and TDT2 significantly reduced carrageenan-induced inflammation. (iasp-pain.org)
If the transitional cell state governed by OGG1 remains responsive to inflammatory mediators instead of differentiation, the collateral damage provides positive feedback to inflammation, ascribing inflammatory remodeling to one of the drivers in chronic pathologies. (lu.se)

To minimize the potential morbidity and mortality from drug-induced respiratory diseases, healthcare providers should be familiar with the possible adverse effects of the medications they prescribe. (medscape.com)
Drug-induced pulmonary toxicity is a diagnosis of exclusion. (medscape.com)
Radiologic patterns observed in drug-induced pulmonary toxicity are highly variable and depend on the type of adverse reaction the patient is experiencing. (medscape.com)
Most drug-induced pulmonary toxicities involve the parenchyma, thus, interstitial infiltrates may be demonstrated on radiographs. (medscape.com)
If the drug-induced pulmonary toxicity causes airway obstruction, then the FEV 1 /FVC ratio and FEV 1 will be reduced. (medscape.com)
In general, bronchoscopy with transbronchial biopsy is not helpful in establishing the diagnosis of drug-induced pulmonary toxicity. (medscape.com)
Bronchoalveolar lavage (BAL) can contribute to the expected clinicopathologic pattern of a given drug-induced lung disease such as identifying eosinophils in a drug-induced eosinophilic pneumonia. (medscape.com)
Generalized itching without apparent skin lesions caused by a drug is called drug-induced itch. (psychiatrist.com)
4 Although a variety of cutaneous adverse effects have been reported with clonazepam, drug-induced itch as an isolated side effect has not yet been reported. (psychiatrist.com)
Here, we report a case of a 22-year-old male patient with depressive disorder who developed drug-induced itch while taking clonazepam. (psychiatrist.com)
Drug-induced pruritus was considered, and clonazepam was stopped. (psychiatrist.com)
6 weeks), and as with other instances of acute drug-induced itch, it improved with cessation of the culprit drug. (psychiatrist.com)
The pathophysiologic mechanism of drug-induced itch is largely unknown except for a few specific drugs that cause it. (psychiatrist.com)
Of hundreds of etiologies of itch, drug-induced pruritus is especially important because of its avoidable nature. (psychiatrist.com)
Treatment of drug-induced itch is not complete without cessation of the suspected drug. (psychiatrist.com)
Hence, it is important to report each case of drug-induced itch, or other adverse drug reactions, for larger interests of the medical fraternity. (psychiatrist.com)
Drug-induced (hypersensitive) interstitial nephritis, analgetic nephropathy, urate nephropathy. (greek.doctor)
Acute drug-induced interstitial nephritis occurs as an adverse reaction to many different drugs, which is why this condition is also called hypersensitive or allergic interstitial nephritis. (greek.doctor)
Several variants of the disease exist, including pemphigus vulgaris, pemphigus foliaceous, and drug-induced pemphigus. (medscape.com)
Patients with drug-induced pemphigus have autoantibodies that are either circulating or tissue bound. (medscape.com)
Secondary infections may occur in drug-induced pemphigus because of the disruption of the skin barrier. (medscape.com)
A variety of drugs have been implicated in the onset of drug-induced pemphigus. (medscape.com)
Thiol drugs are reported most frequently as the culprits of drug-induced pemphigus. (medscape.com)
Penicillamine, captopril, and enalapril are the thiol drugs most often associated with drug-induced pemphigus. (medscape.com)

The causes and precise pathophysiology of acute exacerbations are difficult to determine, so treatment is usually broadly based, encompassing imprecisely targeted bronchodilator, corticosteroid, and antibiotic therapy, supplemental oxygen, and physiotherapy. (atsjournals.org)
The pathophysiology of asparaginase induced pancreatitis is still unclear. (ina-jghe.com)

Peginterferon Alfa2a Plus Ribavirin for Chronic Hepatitis C Virus Infection," The New England Journal of Medicine, Vol. 347, No. 13, 2002, pp. 975982. (scirp.org)
Immunization with rTcSSP4 protein makes mice more susceptible to trypomastigote infection, with high mortality rates, whereas mice immunized with a eukaryotic expression plasmid containing the TcSSP4 cDNA were able to control the acute phase of infection. (ijbs.com)
Rosales-Encina, J.L. A DNA Vaccine Encoding for Tc SSP4 Induces Protection against Acute and Chronic Infection in Experimental Chagas Disease. (ijbs.com)
However, development of an acute insult, such as infection or bleeding, in preexisting chronic liver disease can lead to development of ACLF, which has been elegantly described by Bajaj and colleagues in the most recent ACG guidelines on ACLF . (medscape.com)
Gao L, Weck MN, Nieters A, Brenner H. Inverse association between a pro-inflammatory genetic profile and Helicobacter pylori seropositivity among patients with chronic atrophic gastritis: enhanced elimination of the infection during disease progression? (medscape.com)
In the United States, 2,890 cases of acute hepatitis B were reported to CDC in 2011, and an estimated 18,800 new cases of hepatitis B occurred after accounting for underreporting of cases and asymptomatic infection. (cdc.gov)
Although the rate of acute hepatitis B virus (HBV) infections have declined approximately 89% during 1990-2011, from 8.5 to 0.9 cases per 100,000 population in the United States, the risk for occupationally acquired HBV among HCP persists, largely from exposures to patients with chronic HBV infection. (cdc.gov)
However, while the vaccine is statistically effec- effusion) or even a mild acute upper or lower respiratory tract tive in preventing carriage of vaccine-related strains, a number infection at the time of enrollment. (cdc.gov)
This underlying chronic infection leaves COPD patients particularly vulnerable to acute viral infections, which further destabilize host immunity to bacteria. (frontiersin.org)
Another major consequence of susceptibility to infection is that people with underlying severe disease frequently develop acute exacerbations of COPD (AECOPD). (frontiersin.org)
Patients who have recovered from coronavirus disease 2019 (COVID-19) infection may experience chronic fatigue when exercising, despite no obvious heart or lung abnormalities. (mdpi.com)
4 The acute form, also called Katayama fever, usually occurs weeks to months after the initial infection, when eggs are produced. (appliedradiology.com)
Patients with a chronic infection caused by S haematobium most commonly present with hematuria, dysuria, urinary frequency, and suprapubic discomfort. (appliedradiology.com)
This syndrome encompasses classic symptoms of chronic rhinoconjunctivitis, nasal polyps, and asthma akin to a protracted viral respiratory infection. (medscape.com)
Chronic hepatitis B virus infection (48.2 %) and hepatitis C virus infection (38.2%) were the most frequently identified risk factors. (who.int)

Research on the etiology and pathogenesis of acute and chronic pancreatitis. (nih.gov)
The Acute and Chronic Pancreatitis program supports a broad range of research topics on the etiology and pathogenesis of acute and chronic pancreatitis. (nih.gov)

Diagnosis is primarily based on history as specific IgE and skin prick tests are typically negative and the exclusion of other disorders that present similar clinical features, such as infectious gastroenteritis, celiac disease, inflammatory bowel disease, necrotizing enterocolitis, food protein-induced enteropathy, food protein-induced proctocolitis, and eosinophilic gastroenteritis, among others. (wikipedia.org)
Indeed, while the fast response to stress includes plasticity enhancing effects associated with improved cognition, the long-term adaptive changes induced by stress, in particular following chronic stress, can be deleterious, leading to impaired function, enhanced susceptibility, or triggering of mood and anxiety disorders. (hindawi.com)

IL-1beta is one of a family of proinflammatory cytokines thought to be involved in many acute and chronic diseases. (ox.ac.uk)
The average UK adult consumes less than three portions of fruit and vegetables daily, despite evidence to suggest that consuming five portions daily could help prevent chronic diseases. (cambridge.org)
As with patients with chronic steroid-induced myopathy, patients with these diseases have difficulty rising from chairs and climbing stairs. (livestrong.com)
Auto-antibodies induced neurological diseases show various clinical phenotypes (see details in Table 1 ). (springer.com)
Some people with asthma or other chronic lung diseases may be more sensitive to breathing chlorine than others. (cdc.gov)
Bowel tolerance doses of ascorbic acid ameliorate the acute symptoms of many diseases. (doctoryourself.com)
This loss is due in large part to acute events such as some cardiovascular diseases and injuries. (who.int)
Similar to other high-risk occupations, research efforts and occupational safety and health programs have historically focused on identifying and preventing acute injuries and exposures, but less emphasis has been placed on research and prevention programs relating to chronic diseases or injuries such as occupational noise-induced hearing loss. (cdc.gov)

Some of these drugs induce antibody formation, which results in acantholysis via a mechanism identical to that found in idiopathic pemphigus. (medscape.com)

The lungs can be damaged by acute inhalation exposures as well as suffering effects from more chronic occupational exposures. (cdc.gov)
The kidneys can be damaged with both acute high-dose but more commonly, long-term chronic exposures. (cdc.gov)
The bone disease that occurs with above average chronic exposures is thought to be secondary to cadmium's effects on the kidney. (cdc.gov)
The lungs are a target organ in acute high-dose exposures to inhaled cadmium fumes. (cdc.gov)
Acute and chronic exposures to these chemicals can cause temporary or permanent hearing loss. (ohsonline.com)

The detailed mechanisms of oxygen-induced hypercapnia were examined in 22 patients during an acute exacerbation of chronic obstructive pulmonary disease. (atsjournals.org)
Therefore, spinal AMPA receptor phosphorylation contributes to the mechanisms underlying stress-induced pain transition. (jneurosci.org)
To date, the neurobiological mechanisms that underlie the transition from adaptive acute pain to maladaptive chronic pain are not fully understood ( Mifflin and Kerr, 2014 ). (jneurosci.org)
Much of what is known about sex differences in the stress-induced activity of the HPA axis and their underlying mechanisms comes from studies done in rodents. (nature.com)
This mini-review summarizes the pathophysiological mechanisms and aims to establish the basis of "auto-antibody-induced cerebellar synaptopathies. (springer.com)
Thiol drugs are postulated to induce acantholysis through biochemical mechanisms without antibody formation. (medscape.com)
Nonthiol drugs are more likely to induce acantholysis via immune mechanisms. (medscape.com)

During an acute FPIES episode, ondansetron is often used to control symptoms in children over 6 months of age. (wikipedia.org)
Patients with chronic liver disease experience a slow deterioration in liver function that leads to symptoms of end-stage liver disease, such as variceal bleeding, ascites, spontaneous bacterial peritonitis , and HE. (medscape.com)
In patients with AIA, acute symptoms are superimposed on a background of chronic severe asthma. (medscape.com)
Lesser doses often have little effect on acute symptoms but assist the body in handling the stress of disease and may reduce the morbidity of the disease. (doctoryourself.com)

Acute and chronic nephropathy induced by fluindione must be addressed. (hal.science)

We are particularly interested in articles describing the time-dependent functional, cellular, morphological, and behavioral consequences of acute and chronic physical or psychological stress in brain areas involved in stress response, throughout lifespan. (hindawi.com)

Immunization of mice with plasmids containing genes of Trypanosoma cruzi induces protective immunity in the murine model of Chagas disease. (ijbs.com)
Previously, we showed that chronic social isolation changes subsequent social behaviors in adult mice by reducing expression of PDE11A4 in the membrane fraction of the ventral hippocampus (VHIPP). (frontiersin.org)
Both acute and chronic social isolation decrease PDE11A4 expression in adult but not adolescent mice. (frontiersin.org)
Together, these data suggest that isolation-induced decreases in PDE11A4 may alter subsequent social behavior via increased neuroinflammatory processes in adult mice. (frontiersin.org)
Subthreshold stimulation induced spinal long-term potentiation in GluA1 phosphomimetic mutant mice, but not in wild-type mice. (jneurosci.org)
We investigated the effects of chronic morphine treatment on subsequent morphine signaling at MThal-DMS synapses and MThal cell bodies in male and female mice. (iasp-pain.org)
Surprisingly, chronic morphine treatment increased subsequent morphine inhibition of MThal-DMS synaptic transmission (morphine facilitation) in male, but not female, mice. (iasp-pain.org)
At MThal cell bodies, chronic morphine treatment decreased subsequent morphine activation of potassium conductance (morphine tolerance) in both male and female mice. (iasp-pain.org)
In knockin mice expressing phosphorylation-deficient MORs, chronic morphine treatment resulted in tolerance to, rather than facilitation of, subsequent morphine signaling at MThal-DMS terminals, suggesting phosphorylation-deficiency unmasks adaptations that counter the facilitation observed at presynaptic terminals in wild-type mice. (iasp-pain.org)
Mice were used for assessment of acute toxicity of TDT derivatives and no major toxic/bizarre responses were observed. (iasp-pain.org)

The course of chronic obstructive pulmonary disease (COPD) is characterized by acute exacerbations, commonly requiring hospital admission and often associated with the development of respiratory failure. (atsjournals.org)
Chronic obstructive pulmonary disease (COPD) is an umbrella term encompassing multiple lung pathologies (including emphysema, chronic bronchitis and bronchiolitis) that manifest into persistent and poorly reversible airflow limitation. (frontiersin.org)

Injections of radiocontrast agents are a frequent cause of acute decreases in renal function, occurring most often in patients with chronic renal insufficiency and diabetes mellitus. (nih.gov)
Acute tubular necrosis is the most frequent cause of acute renal failure. (greek.doctor)

The prognosis is very good for the toxic form, but there is a more than 50% death rate in the ischaemic type as these cases often lead to acute renal failure. (greek.doctor)

This study investigated the in vivo effects of acute metabolic acidosis (AMA) and chronic metabolic acidosis (CMA) on hemodynamic parameters and endothelial function. (bvsalud.org)

Acute inflammatory lesions improved over the next 24 hours. (bcmj.org)

Occupational cohort studies have suggested possible associations between chronic exposure to cadmium, particularly cadmium oxide, and cancers of the lung, prostate, and genitourinary system such as renal carcinoma. (cdc.gov)
Epicutaneous S. aureus exposure causes robust itch and scratch-induced damage. (iasp-pain.org)
Chronic opioid exposure induces tolerance to the pain-relieving effects of opioids but sensitization to some other effects. (iasp-pain.org)
It is characterized by a gradual worsening of high-frequency hearing thresholds over time following chronic and sometimes acute exposure to excessive noise levels. (cdc.gov)
It is possible to see a unilateral noise -induced hearing loss when the exposure conditions favor one side of the head. (cdc.gov)

Bacteria can release endotoxins like lipopolysaccharide (LPS) or other pathogenicity factors such as lipopoteins/peptides (LP) from their cell envelope, even due to treatment with conventional antibiotics, being able to activate Toll-like receptors (TLRs) and induce a strong inflammatory response. (nature.com)
Our study uncovers activation of a Th2-driven immune/inflammatory response during pulmonary fibrosis development induced by MWCNT. (cdc.gov)
The findings provide novel insights into the molecular events that control the transition from an acute inflammatory response to chronic fibrosis through Th2 functions in CNT-exposed lungs. (cdc.gov)

Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis. (ox.ac.uk)
These data directly demonstrate how acute tissue injury in the lung, initiated by a highly proinflammatory cytokine, IL-1beta, converts to progressive fibrotic changes. (ox.ac.uk)
In vivo activation of a T helper 2-driven innate immune response in lung fibrosis induced by multi-walled carbon nanotube s. (cdc.gov)
Here we analyzed the molecular pathways and regulators underlying the pathologic development of CNT-induced lung fibrosis. (cdc.gov)

An acute radiocontrast-induced decrease in renal function was defined as an increase in the base-line serum creatinine concentration of at least 0.5 mg per deciliter (44 mumol per liter) within 48 hours after the injection of radiocontrast agents. (nih.gov)
These results indicate that AMA, but not CMA, potentiated the Ach-induced decrease in blood pressure and led to an increase in plasma NOx, reinforcing the effect of pH imbalance on vascular tone and blood pressure control. (bvsalud.org)

Patients not treated then enter the chronic form of the disease where the immune response to the eggs is not as severe. (appliedradiology.com)
Genome-wide microarray analyses of the lungs identified a range of differentially expressed genes that potentially function in the acute-to-chronic transition through pathways involving immune and inflammatory regulation, responses to stress and extracellular stimuli, and cell migration and adhesion. (cdc.gov)
In this review, we discuss the substrate-specific read through OGG1 has evolved in regulating the innate immune response, controlling adaptations of the airway to environmental and inflammatory injury, with a focus on the reader function of OGG1 in initiation and progression of epithelial to mesenchymal transitions in chronic pulmonary disease. (lu.se)

Induction of Antinuclear Antibody after Interferon Therapy in Patients with TypeC Chronic Hepatitis: Its Relation to the Efficacy of Therapy," Scandinavian Journal of Gastroenterology, Vol. 31, No. 7, 1996, pp. 716722. (scirp.org)
in particular, the hypercapnia induced by oxygen therapy in some patients with COPD. (atsjournals.org)
Some patients remain sensitive to hypoxia and hypercapnia, whereas others have absent responses, and responses differ between stable states and acute exacerbations ( 2-9 ). (atsjournals.org)
We prospectively studied 78 patients with chronic renal insufficiency (mean [+/- SD] serum creatinine concentration, 2.1 +/- 0.6 mg per deciliter [186 +/- 53 mumol per liter]) who underwent cardiac angiography. (nih.gov)
In patients with chronic renal insufficiency who are undergoing cardiac angiography, hydration with 0.45 percent saline provides better protection against acute decreases in renal function induced by radiocontrast agents than does hydration with 0.45 percent saline plus mannitol or furosemide. (nih.gov)
In the severe form of acute FPIES, a person will vomit until dehydration and until a shock-like state, which occurs in 15% of patients. (wikipedia.org)
Over half of patients experiencing an acute FPIES reaction may develop thrombocytosis (platelets >500x109/L). In both chronic and acute FPIES, both methemoglobinemia and metabolic acidosis (mean pH around 7.03 in one study) have been reported. (wikipedia.org)
Long term complications may be devastating for patients which include of pseudocyst pancreas and chronic pancreatitis. (ina-jghe.com)
It was evaluated for patients with chronic aphasia. (bmj.com)
In the present study we investigated the efficacy of a modified CIAT schedule and included patients with sub-acute stroke. (bmj.com)
Conclusions Both CIAT and conventional therapy performed with equal intensity are efficacious methods for patients with sub-acute aphasia. (bmj.com)
Conclusively, our data suggest a novel therapeutic target for the treatment of patients with acute and chronic skin infections. (nature.com)
The aim of this study was to assess the effects of resistance exercise and stretching on sleep, mood, and quality of life in chronic insomnia patients. (scielo.br)
Moderate-intensity resistance exercise and stretching led to similar improvements in objective and subjective sleep in patients with chronic insomnia. (scielo.br)
HBsAg was confirmed by HCC is reported to account for about ral hospital providing special care for ELISA test (Abbot Laboratories), and 4.7%-7.3% of patients with chronic patients from the whole of Yemen. (who.int)

Acute but not chronic metabolic acidosis potentiates the acetylcholine-induced reduction in blood pressure: an endothelium-dependent effect. (bvsalud.org)

Inclusion criteria were clinical diagnosis of first-ever stroke, aphasia in the sub-acute stage and German speakers. (bmj.com)
Clinical diagnosis of levamisole-induced vasculitis was made and antibiotics were discontinued. (bcmj.org)

The present review accordingly focuses on advances revealed from rodent studies in our understanding of sex differences in the stress-induced activity of the HPA axis in adulthood. (nature.com)

However, it is unclear how the transition from acute to chronic pain occurs. (jneurosci.org)
Noise-induced hearing loss is always sensorineural and mostly occurs because of damage to the tiny hairs in the cochlea of the inner ear which work to stimulate the nerve endings. (ohsonline.com)

Recent advances have uncovered the non-random distribution of 7, 8-dihydro-8-oxoguanine (8-oxoGua) induced by reactive oxygen species, which is believed to have epigenetic effects. (lu.se)

The mechanism of CNT-induced fibrogenesis is largely unknown. (cdc.gov)

In chronic model, WIN 55,212-2 (0.33, 1 and 3 mg/kg) significantly attenuated NTG-induced hyperalgesia through both CB1 and CB2 receptors. (ac.ir)
Our findings revealed that CCI induced clear-cut allodynia and hyperalgesia which was reversed by TDT1 and TDT2. (iasp-pain.org)
Overall, these results suggest that TDT1 and TDT2 exert their neuroprotective and analgesic potentials by ameliorating CCI-induced allodynia, hyperalgesia, neuroinflammation and neuronal degeneration in a dose-dependent manner. (iasp-pain.org)

Here we seek extend these findings by determining 1) if isolation-induced decreases in PDE11A4 require chronic social isolation or if they occur acutely and are sustained long-term, 2) if isolation-induced decreases occur uniquely in adults (i.e., not adolescents), and 3) how the loss of PDE11 signaling may increase neuroinflammation. (frontiersin.org)
Selected Thiadiazine-Thione Derivatives Attenuate Neuroinflammation in Chronic Constriction Injury Induced Neuropathy. (iasp-pain.org)

H. Kato, H. Ikeuchi and M. Nakamura, "Acute Exacerbation of Liver Disease Induced by Pegylated Interferon Alpha2a Treatment for Chronic Hepatitis C," International Journal of Clinical Medicine , Vol. 1 No. 1, 2010, pp. 1-5. (scirp.org)
Clinical Relevance of Opioid-Induced Immunosuppression: Are All Drugs Similar? (routledge.com)
Chronic postsurgical pain is a serious issue in clinical practice. (jneurosci.org)
Although a high proportion of healthy vaccine recipients in clinical trials respond to hepatitis B (HepB) vaccination, the proportion of responders can be lower among the general population, particularly among persons with chronic medical conditions ( 6 , 7 ). (cdc.gov)

Rates of alcohol-induced deaths for persons aged 45-64 years increased from 17.3 per 100,000 population in 1999 to 26.0 in 2017. (cdc.gov)

Interestingly, targeted mutation of the GluA1 phosphorylation site Ser831 significantly inhibited stress-induced prolongation of incisional pain. (jneurosci.org)
In the chronic intervention study FVPD consumption was found to significantly increase dietary carotenoids ( P =0·001) and vitamin C ( P =0·003). (cambridge.org)

PegIFN induced acute liver failure is quite rare, but clinicians should aware of this lifethreatening side effect during and after interferon therapy. (scirp.org)
M. Shindo, A. M. D. Bisceglie and J. H. Hoofnagle, "Ac ute Exacerbation of Liver Disease during Interferon Alfa Therapy for Chronic Hepatitis C," Gastroenterology, Vol. 102, No. 4, 1992, pp. 14061408. (scirp.org)
Acute liver failure (ALF) is a rare condition occurring in people without preexisting liver disease that can result in hepatic failure. (medscape.com)
How do you distinguish ALF from acute-on-chronic liver failure (ACLF) in a patient with chronic liver disease? (medscape.com)

Suspected clonazepam-induced bullous dermatosis in a patient with respiratory failure. (psychiatrist.com)

Relapsing or chronic pancreatitis can lead to exocrine and endocrine pancreatic insufficiency. (nih.gov)
Acute pancreatitis is one of the serious side effects of l-asparaginase administration and may lead to interruption of chemotherapy cycle. (ina-jghe.com)
Asparaginase induced pancreatitis is rare among adult due to the nature of ALL which commonly occurred in children population. (ina-jghe.com)
Here we present 18-year-old male with ALL and asparaginase induced acute necrotizing pancreatitis which complicated to chronic pancreatitis and pseudocyst. (ina-jghe.com)

Thus, transient acute pain is an important feature of the adaptive response to damage. (jneurosci.org)

In adult female rodents, acute HPA function following a stressor is markedly greater than it is in males, and this difference has largely been attributed to modulation by the gonadal hormones testosterone and estradiol. (nature.com)

Isolation-induced decreases in PDE11A4 expression appear to be functional as social isolation elicited changes in PDE11A-relevant signal transduction cascades (i.e., decreased pCamKIIα and pS6-235/236) and behavior (i.e., increased remote long-term memory for social odor recognition). (frontiersin.org)
Interestingly, we found that isolation-induced decreases in membrane PDE11A4 correlated with increased expression of interleukin-6 (IL-6) in the soluble fraction, suggesting pro-inflammatory signaling for this cytokine. (frontiersin.org)
In acute model, we found that WIN 55,212-2 (almost high doses) decreases the level of pain mainly through CB1 receptor due to CB1 antagonist abrogates its protective effects, however, in formalin test CB2 receptors also had crucial roles in both phases at 3 mg/kg of WIN 55,212-2. (ac.ir)

Food protein-induced enterocolitis syndrome (FPIES) is a systemic, non IgE-mediated response to a specific trigger within food - most likely food protein. (wikipedia.org)
Nowak-Wegrzyn A, Muraro A. Food protein-induced enterocolitis syndrome. (wikipedia.org)
A Model for Understanding the Etiology of Major Depression and Chronic Fatigue Syndrome? (routledge.com)
What induces tics in Tourette syndrome? (psychcentral.com)
This syndrome is referred to as aspirin-induced asthma (AIA). (medscape.com)

Alcohol-induced causes exclude unintentional injuries, homicides, and other causes indirectly related to alcohol use, as well as newborn deaths associated with maternal alcohol use. (cdc.gov)
Gao L, Weck MN, Stegmaier C, Rothenbacher D, Brenner H. Alcohol consumption and chronic atrophic gastritis: population-based study among 9,444 older adults from Germany. (medscape.com)

The high expression of IL-1beta in the first week after injection was accompanied by local increase of the proinflammatory cytokines IL-6 and TNF-alpha and a vigorous acute inflammatory tissue response with evidence of tissue injury. (ox.ac.uk)
Acute tubular necrosis (ATN, also called acute tubular injury) is a condition characterized morphologically by damaged tubular epithelial cells and by acute decline in renal function. (greek.doctor)

ABSTRACT: In the case reported here, cocaine abuse led to levasimole-induced vasculitis and chronic ulcers. (bcmj.org)

Cadmium Toxicity: How Does Cadmium Induce Pathogenic Changes? (cdc.gov)

Here we showed that social defeat stress enhanced plantar incision-induced AMPA receptor GluA1 phosphorylation at the Ser831 site in the spinal cord and greatly prolonged plantar incision-induced pain. (jneurosci.org)

We then demonstrated that MWCNT induced the expression of Th2 cytokines interleukin (IL)-4 and IL-13, and a panel of signature downstream genes, such as Il4i1, Chia, and Ccl11/Eotaxin, time dependently. (cdc.gov)

Chronic morphine induces adaptations in opioid receptor signaling in a thalamo-striatal circuit that are location-dependent, sex-specific and regulated by mu opioid receptor phosphorylation. (iasp-pain.org)
This study aimed to determine how chronic treatment with morphine, a prototypical opioid agonist, induced adaptations to subsequent morphine signaling in different subcellular contexts. (iasp-pain.org)
This study found that within medial thalamic projection neurons, chronic morphine treatment induced adaptations that were not ubiquitous. (iasp-pain.org)

it is psychoactive and can induce alterations in most if not all brain systems and structures. (who.int)

Interestingly, TDT1 and TDT2 substantially reduced the mRNA expression and protein level of Iba1, implying that TDT1 and TDT2 may mitigate CCI-induced astrogliosis. (iasp-pain.org)

Roles of Mu-Opioid Receptor and Endogenous Opiates in Stress-Induced Immunosuppression. (routledge.com)
Chronic Stress Induces Death of Lymphocytes. (routledge.com)
These gonadal hormones are produced by the hypothalamic-pituitary-gonadal (HPG) axis and have been shown to determine sex differences in adult HPA function after acute stress via their activational and organizational effects. (nature.com)
Moreover, questions remain regarding sex differences in the activity of the HPA axis following chronic stress and the underlying contributions of gonadal hormones and sex chromosomes. (nature.com)
We primarily outline what is known about how gonadal hormones and sex chromosomes modulate HPA axis activity following acute stress, and then focus on sex-biased HPA axis activity post-chronic stress, which is far less well understood. (nature.com)

AECOPD are defined as "a sustained worsening of the patient's condition, from the stable state and beyond normal day-to-day variations, that is acute in onset and necessitates a change in regular medication in a patient with underlying COPD" ( 7 ). (frontiersin.org)

A 66yearold female was referred to a local clinic for the treatment of chronic hepatitis C. Her family physician started the administration of PegIFN alpha2a in combination with ribavirin in September, 2008. (scirp.org)
Peginterferon Alfa2b Plus Ribavirin Compared with Interferon Alfa2b Plus Ribavirin for Initial Treatment of Chronic Hepatitis C: A Randomised Trial," Lancet,Vol. 358, No. 9286, 2001, pp. 958965. (scirp.org)
Nonpharmacologic treatment of chronic insomnia. (scielo.br)
Treatment of dilated cardiomyopathy is essentially the same as treatment of chronic heart failure (CHF). (medscape.com)

Among the anxiolytic medications, diazepam, nitrazepam, and oxazepam have been reported to induce itch. (psychiatrist.com)
S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. (iasp-pain.org)

In many cases, it can be extremely difficult to distinguish noise-induced hearing loss from chemical induced hearing loss. (ohsonline.com)

Noise induced hearing loss (NIHL) is a fairly common illness. (ohsonline.com)

Here we report a case of acute isoniazid-induced peripheral neuropathy with predominant motor functional impairment associated with tetraplegia. (who.int)

Inflammation11

Drug-induced24

Pathophysiology2

Infection15

Pathogenesis2

Disorders2

Diseases8

Drugs induce1

Exposures5

Mechanisms7

Symptoms4

Nephropathy1

Behavioral1

Mice10

Obstructive pulmonary disease2

Frequent cause of acute2

Renal failure1

Effects of acute1

Lesions1

Exposure5

Inflammatory response3

Lung4

Decrease2

Immune3

Patients15

Metabolic acidosis1

Diagnosis2

Adulthood1

Occurs2

Reactive oxygen1

Mechanism1

Hyperalgesia3

Neuroinflammation2

Clinical4

20171

Significantly2

Liver4

Respiratory1

Pancreatitis4

Transient1

Stressor1

Decreases3

Syndrome5

Alcohol2

Injury2

Abstract1

Toxicity1

AMPA1

Cytokines1

Adaptations3

Alterations1

Interestingly1

Stress5

Onset1

Treatment of chronic4

Itch2

Distinguish1

Illness1

Neuropathy1