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  • patent ductus art
  • Indometacin has also been used clinically to delay premature labor , reduce amniotic fluid in polyhydramnios , and to close patent ductus arteriosus . (wikipedia.org)
  • Indomethacin injection is used to treat patent ductus arteriosus (PDA) in premature infants (babies born too early) who weigh between 500 and 1750 grams. (mayoclinic.org)
  • The purpose of the study is to determine the safety and efficacy of ibuprofen, compared with indomethacin, in the treatment for the closure of the patent ductus arteriosus in premature bab. (bioportfolio.com)
  • We hypothesize that feeding preterm infants while they receive indomethacin or ibuprofen therapy for treatment of a patent ductus arteriosus will decrease the incidence of feeding intolera. (bioportfolio.com)
  • Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis. (bioportfolio.com)
  • capsule
  • The indomethacin controlled release formulations of the present invention comprise a capsule having coated pellets which exhibit both immediate release and sustained release characteristics in the same capsule. (google.com.au)
  • prostaglandins
  • Since indomethacin is an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease of prostaglandins in peripheral tissues. (nih.gov)
  • For instance, indometacin inhibits both cyclooxygenase-1 and cyclooxygenase-2 , which then inhibits the production of prostaglandins in the stomach and intestines responsible for maintaining the mucous lining of the gastrointestinal tract . (wikipedia.org)
  • formulation
  • In accordance with the present invention, the controlled release formulation contains coated pellets of indomethacin of only one type. (google.com.au)
  • This invention relates to a novel oral pharmaceutical formulation of indomethacin having controlled release properties. (google.com.au)
  • The formulation provides an immediate release indomethacin for elevating blood levels to pharmacologically effective levels and sustained release indomethacin for maintaining those levels. (google.com.au)
  • tension-type hea
  • The article presents abstracts of several studies related to headaches including "Nummular headache dramatically responsive to indomethacin and literature review," "A daily tension-type headache in a child with an ectopic neurohypophysis and "Tumor necrosis factor receptor-associated periodic. (ebscohost.com)
  • Injection
  • Bedford Laboratories™, a division of Ben Venue Laboratories, Inc., a provider of select specialty injectables, is pleased to announce the addition of Indomethacin for Injection to its existing product line. (news-medical.net)
  • Indomethacin injection works by causing the PDA to constrict, and this closes the blood vessel. (mayoclinic.org)
  • side
  • Stop taking indomethacin and get medical help right away if you notice any of the following rare but serious side effects: bloody or black/tarry stools, persistent stomach/ abdominal pain , vomit that looks like coffee grounds, chest/jaw/left arm pain , shortness of breath , unusual sweating , weakness on one side of the body, sudden vision changes, slurred speech. (medicinenet.com)
  • Read user comments about the side effects, benefits, and effectiveness of indomethacin submicronized oral. (webmd.com)
  • anti-infl
  • An old anti-inflammatory drug, Indomethacin, has been found to rank highly as a potential compound to fight Epithelial Ovarian Cancer (EOC), according to research by Dr. Anil Belur Nagaraj, PhD, at the Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio. (canceractive.com)
  • increase
  • may increase nephrotoxicity of cyclosporin Indomethacin may increase serum concentrations of digoxin, methotrexate, lithium, and aminoglycosides. (medindia.net)