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  • MPNs
  • Rare Disease Day also marks the opening of nominations for the 2018 MPN Heroes® Recognition Program, which honors the individuals and organizations that contribute to bringing understanding and strength to those living with MPNs. (mpnresearchfoundation.org)
  • cancers
  • As in most cancers, short telomeres are one of the features of CML cells, and telomere shortening accentuates as the disease progresses from the chronic phase to the blastic phase. (mdpi.com)
  • genomic
  • LightMix Package JAK2V617F genomic LightMix for the recognition of individual MTHFR C677T and LightMix for the recognition of individual Plasminogen Activator Inhibitor 4G/5G TIB MOLBIOL berlin Germany) or regarding the Aspect XII C46T gene polymorphism with a process released from PLX-4720 Tirodo I. et al. (biodigestor.net)
  • clonal
  • Although most individual telomeres are short, some of them are lengthened, and long individual telomeres occur non-randomly and might be associated with clonal selection. (mdpi.com)
  • caregivers
  • Offers services to deaf, deafened and hard of hearing individuals and their families and caregivers. (cioc.ca)
  • Advocate and promote the development of support services, education, and research for those affected by Alzheimer disease or other dementia and their caregivers. (informationperth.ca)
  • clinical
  • He directs The Program in Novel Therapeutics , a clinical research program in musculoskeletal disease. (northwell.edu)
  • 1 Especially the highly immunogenic D (RH1) antigen carried by the RhD polypeptide is of clinical relevance for transfusion medicine and prenatal management, because anti-D alloimmunization in D-negative individuals may be responsible for severe hemolytic transfusion reactions and is a major cause of hemolytic disease of the newborn. (bloodjournal.org)
  • mechanisms
  • CML represents a good model to study mechanisms responsible for dynamic changes of individual telomere lengths and the remodeling of telomeric nuclear organization throughout cancer progression. (mdpi.com)
  • Organization
  • Feb. 28, 2018 - Incyte Corporation (Nasdaq:INCY) joins the National Organization for Rare Disorders (NORD), the European Organization for Rare Diseases (EURORDIS), and other rare disease health organizations and advocates in recognizing Rare Disease Day 2018. (mpnresearchfoundation.org)
  • routine
  • In contrast, the presentation of myeloproliferative diseases is usually subtle, or found upon routine blood testing. (thecardiologyadvisor.com)
  • Occasionally, in some individuals the simultaneous presence of D-positive and D-negative RBCs is identified by a mixed-field agglutination pattern in routine RhD typing that is most frequently due to previous D-mismatched RBC transfusions or hematopoietic stem-cell transplantation (HSCT). (bloodjournal.org)
  • diagnosis
  • The diagnosis of a myeloproliferative disease is usually made by a careful history (fevers, sweats, weight loss, early satiety, ruddy complexion), physical examination (splenomegaly, skin color), laboratory examination (complete blood count, including leukocyte differential), and radiological evaluation (abdominal ultrasound). (thecardiologyadvisor.com)
  • cope
  • You may find that knowing more about the disease and its treatment can help you cope. (lls.org)