• This coordinate-based meta-analysis included voxel-based morphometry (VBM) studies and resting-state voxel-based pathophysiology (VBP) studies of blood flow, glucose metabolism, regional homogeneity, and amplitude of low-frequency fluctuations (ALFF) and fractional ALFF (fALFF). (psychiatryonline.org)
  • We applied different structural imaging techniques such as voxel-based morphometry (VBM), diffusion tensor imaging (DTI), and magnetization transfer imaging (MTI) to study anatomical differences between boys with ADHD and healthy controls, as well as functional magnetic resonance imaging (fMRI) together with independent component analysis (ICA) to detect functional alterations. (unibas.ch)
  • Bilateral amygdala activation was elicited by all odors, regardless of valence. (jneurosci.org)
  • although activations tend to be more bilateral at younger ages (e.g. (biorxiv.org)
  • Many neuroimaging studies have used the verbal n-back task during functional MRI (fMRI) to explore brain activation associated with working memory processing, and n-back task performance is associated with the activations of bilateral frontal and cortical regions [ 6 ]. (biomedcentral.com)
  • 2011) reported decreased bilateral insula activation in people with BN, while Schienle et al. (biomedcentral.com)
  • Furthermore, the increased bilateral ACC activation in BN seen by Schienle et al. (biomedcentral.com)
  • By comparing paired (odor/face) and unpaired (face only) conditions, odor-evoked neural activations could be isolated specifically. (jneurosci.org)
  • Our results indicate that a disassociated neural network underlies the dynamic construction of speech mental imagery independent of auditory perception. (elifesciences.org)
  • To do this, we develop a deep Siamese framework comprising three-dimensional convolution neural networks for contrastive learning based on individual-level spatial maps estimated via a fully automated fMRI independent component analysis approach. (biorxiv.org)
  • 2006]. Recent studies on ASD have shown aberrant neural activity during semantic processing, for example, reduced activation in the left inferior frontal gyrus (IFG) in adults with ASD as compared to healthy controls [Harris et al. (fulbright.org.tw)
  • I am also interested in applying a wider variety of techniques from to these large scale problems of neurological data analysis in general, and in particular the issue of neural coding. (mpg.de)
  • I am also looking at applications of conditional mutual information in neural data analysis, for example when dealing with correlated stimuli, or to provide a form of robust group inference. (mpg.de)
  • 1 , 2 Functional magnetic resonance imaging (fMRI), measuring the Blood Oxygen Level Dependent (BOLD) response to neural activation in the olfactory cortex, has particularly enabled the identification of cortical and subcortical brain structures that participate in olfactory processing. (dovepress.com)
  • Four parallel, independent meta-analyses were calculated using the revised activation likelihood estimation algorithm: all experiment types, all resting-state experiments, all cognitive experiments, and all emotional experiments. (nature.com)
  • Activation likelihood estimation was used for all analyses. (psychiatryonline.org)
  • Further, statistical power analysis has not been considered in the selection of the sample, potentially limiting the statistical power of the study (Cohen, 1992). (savedelicious.com)
  • Linear mixed effects models, analysis of variance, t-tests, and mediation models were used for statistical analyses. (stanford.edu)
  • Despite these facts, the conventional explicit and/or implicit assumptions that underlie the use of SPM, FSL, and other packages designed for fMRI analysis can be stated as follows: (i) Statistical inference using fMRI data is only possible if the image is smoothed by a kernel three times the size of the acquired voxels. (mpg.de)
  • For any scientist who has taken the trouble to study neuroanatomy and neurophysiology, and to track developments in image statistical analysis, these assumptions are all obviously unrealistic. (mpg.de)
  • The motivations for spatial smoothing are these: a) to increase SNR by averaging over adjacent voxels, b) to allow statistical inference of significance using the theory of Gaussian Random Fields, and c) to enable averaging of functional imaging data across groups of subjects, after each subject's brain images have been suitably normalized into a standard template brain volume. (mpg.de)
  • Statistical analyses revealed significant performance improvements over the stimulation and the afterphase, but this learning effect was not modulated by tDCS condition. (surrey.ac.uk)
  • Technically, I am interested in practical techniques for improving calculation or estimation of information theoretic quantities both in terms of improving statistical properties, for example by correcting for the and in terms of improving computational performance, which is important since many analyses require style controls which involve repeating information calculations many times on shuffled or modelled data and can be a significant bottleneck. (mpg.de)
  • Coordinate-based meta-analysis identified spatially convergent structural (VBM) and functional (VBP) abnormalities in major depression. (psychiatryonline.org)
  • 360(1457) 983-993] the relationship between neuronal activation and fMRI signals is formulated as a first-order convolution with a kernel expansion using basis functions (typically two or three), in this paper, we argue in favor of a spatially adaptive GLM in which a local non-parametric estimation of the HRF is performed. (ox.ac.uk)
  • These networks are generally identified either as collections of voxels whose time series correlate strongly with a pre-selected region or voxel, or using data-driven methodologies such as independent component analysis (ICA) that compute sets of maximally spatially independent voxel weightings (component spatial maps (SMs)), each associated with a single time course (TC). (unm.edu)
  • Volume and cortical thickness analyses were performed using the open-source automated software package FreeSurfer. (mdpi.com)
  • In this study, we investigate, for the first time, the use of pairwise-relationships between resting-state independent spatial maps to characterize individuals. (biorxiv.org)
  • Quantitative meta-analyses of this literature, however, have failed to find statistically significant between-study spatial convergence, other than transdiagnostic-only effects. (psychiatryonline.org)
  • iv) The importance of a given brain area for a specific task is indicated only by a positive mean activity, on a scale of 8 mm. (v) Activity in any given brain voxel is statistically independent from any other brain voxel. (mpg.de)
  • Neuroimaging studies have begun to identify important olfactory structures, but one notable feature is the inconsistent activation of piriform cortex ( Zald and Pardo, 2000 ). (jneurosci.org)
  • The secondary analyses identified portions of the subgenual cingulate cortex, hippocampus, amygdala, and putamen as demonstrating convergent abnormalities. (psychiatryonline.org)
  • Negative components showed activation in anterior and posterior cingulate cortex/precuneus and temporal regions, and were interpreted as forming part of the default mode network. (unibas.ch)
  • Compared with motor imagery, motor execution generated higher activation in all 3 regions of interest studied: the supplementary motor area (SMA), primary motor cortex (M1), and thalamus. (jamanetwork.com)
  • The insets display the results from the random-effects general linear model analysis together with the group coordinates of the regions included in the model: the supplementary motor area (SMA), primary motor cortex (M1), and thalamus. (jamanetwork.com)
  • ADHD and OCD patients shared left insula/ventral IFG underactivation and increased activation in posterior default mode network relative to controls, but had disorder-specific overactivation in anterior default mode regions, in dorsal anterior cingulate for ADHD and in anterior ventromedial prefrontal cortex for OCD. (omicsdi.org)
  • This study used positron emission tomography (PET) imaging with the translocator protein (TSPO) ligand 18 F-GE-180 to evaluate microglial activation in liver-transplanted patients under different regimens of immunosuppression. (springer.com)
  • The tertiary analyses (clinical subtypes) showed improved convergence relative to the secondary analyses. (psychiatryonline.org)
  • Our selecting of elevated activation in the ACC during earn studies for the Clinical group may reveal alterations in praise expectancy (Shidara and Richmond 2002 that persist after an especially frustrating occurrence or that medically irritable children Slc38a5 think it is especially rewarding when developments are created towards a preferred objective. (researchassistantresume.com)
  • Dr. Yurgelun-Todd is an expert in the application of structural and functional magnetic resonance imaging, the administration and analysis of neurocognitive tests, and the integration of the results obtained by using multiple imaging modalities combined with clinical assessment. (va.gov)
  • Seed-to-voxel resting-state functional connectivity (FC) analysis was conducted with six seeds in the insula and two seeds in the DMN. (bvsalud.org)
  • Consistent with previous studies, processing of food images was associated with activation of a network of reward areas including the amygdala, striatum and insula. (exeter.ac.uk)
  • In contrast, exploring regions reduced by memantine, we found significant reduction of activations within right lingual gyrus and left superior frontal gyrus in comparison between 2-back and 0-back test. (biomedcentral.com)
  • Positive components included activation in frontal and parietal regions. (unibas.ch)
  • The neuroimaging results showed greater activation in the cuneus and less activation in the left inferior frontal gyrus (IFG) in boys with ASD than TD boys. (fulbright.org.tw)
  • Recently, dictionary learning and sparse coding method has attracted increasing attention in the fMRI analysis field. (elsevierpure.com)
  • This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. (theinfolist.com)
  • This analysis aims to undertake a critical analysis of the study's rationale, design and conclusions. (savedelicious.com)
  • Coordinates showing significant activation and/or connectivity differences between BD participants and controls during resting-state, emotional, or cognitive tasks were extracted. (nature.com)
  • Significant cluster size was defined as 54 voxels or greater. (inquiriesjournal.com)
  • odor memory) contrasts had several areas of significant activation, including many of the classical olfactory brain regions as well as the hippocampus. (dovepress.com)
  • This meta-analysis aims to comprehensively reassess brain activation and connectivity in BD in order to identify replicable differences that converge across and within resting-state, cognitive, and emotional neuroimaging experiments. (nature.com)
  • Based on cross-study comparisons, a recent meta-analysis of neuroimaging results suggests that posterior-dorsal (Brodmann area, BA, 44) and anterior-ventral parts (BA 45) of LIFG contribute differentially to processes of phonologically and semantically cued word retrieval, respectively. (jneurosci.org)
  • Matching fMRI modalities and operational definitions of resilience across studies are essential for meta-analysis. (frontiersin.org)
  • RESULTS: Whilst there was no overall effect of sulpiride on task-dependent activation, individual variation in sulpiride plasma levels predicted the effect of working memory manipulation on activation in the putamen, suggesting a dose-dependent effect of DA antagonism on a striatally based manipulation process. (exeter.ac.uk)
  • Functional connectivity analysis of the human brain in fMRI researches focuses on identifying meaningful brain networks that have coherent activity either during a task or in the resting state. (unm.edu)
  • Our results provide important empirical evidence for researchers in the field of cognitive control for the use of individual ROIs in the frontoparietal network for both univariate and multivariate analysis of fMRI data and serve as another step toward standardization and increased comparability across studies. (mit.edu)
  • The image analysis for the present study considered each participants brain activation patterns rather than grouped results as discussed by Ciccia and colleagues (2006). (inquiriesjournal.com)
  • In particular, the use of videotaped violent scenes can serve as the ideal stimulus for assessing activation patterns in response to violence. (psychiatrictimes.com)
  • Brain activation patterns in response to food cues did not differ between women with and without BN. (biomedcentral.com)
  • The completion of these tasks allowed for a clear overlay of the functional imaging data over the structural data and the identification of activation in pre-specified regions of interest (Frackowiak, Friston, Frith, Dolan, Price, Zeki, Ashburner, & Penny, 2004). (inquiriesjournal.com)
  • Paired t -tests were used to compare differences in the degree of activation between odor identification and odor memory tasks within individuals. (dovepress.com)
  • In this paper, we proposed a novel supervised stochastic coordinate coding (SCC) algorithm for fMRI data analysis, in which certain brain networks are learned with supervised information such as temporal patterns of task designs and spatial patterns of network templates, while other networks are learned automatically from the data. (elsevierpure.com)
  • Sliding window analysis is the most common method used in the analysis of functional connectivity, first introduced by Sakoglu and Calhoun in 2009, and applied to schizophrenia. (wikipedia.org)
  • In secondary meta-analyses, the data were grouped across primary categories, and in tertiary analyses, by medication status and absence of psychiatric comorbidity. (psychiatryonline.org)
  • In order to be accurately interpreted, data from sliding window analysis generally must be compared between two different groups. (wikipedia.org)
  • Recent developments of multivoxel pattern analysis (MVPA) for fMRI data allow for more fine-grained investigations into the functionality and properties of brain systems. (mit.edu)
  • An alternative approach uses independent localizer data for each subject to select the most responsive voxels and define individual ROIs within the boundaries of a group template. (mit.edu)
  • As an example we will show how this method can be used to improve interpretability of estimates from an independent component analysis (ICA) analysis of fMRI data. (ox.ac.uk)
  • Preprocessing analysis of the data included: slice timing correction, realignment and unwarping, co-registration, normalization to the MNI T1 template (Montreal Neurological Institute), and smoothing with a 6 mm isotropic Gaussian kernel. (inquiriesjournal.com)
  • These preprocessing steps allow SPM to combine the functional and structural imaging data into a single image for analysis. (inquiriesjournal.com)
  • Ciccia and colleagues (2006) previous analysis of the group data looked at the brain activation patterns that persisted across all study participants. (inquiriesjournal.com)
  • This data was then looked at in two ways: as a group image (where the 10 second decision points for all of the participants were averaged together), or as individuals (each individual participant's activation using the same ten second marker as the decision point). (inquiriesjournal.com)
  • Model-driven methods such as the general linear model (GLM) regresses exterior task designs from voxel-wise brain functional activity, which is confined because of ignoring the complexity and diversity of concurrent brain networks. (elsevierpure.com)
  • Its application on two independent fMRI datasets has shown the effectiveness of our methods. (elsevierpure.com)
  • This temporal information was used to individualize the functional imaging analysis in SPM. (inquiriesjournal.com)
  • Analyses reveal specific adaptations in the brain, both structural and functional, correlated to individual EBFs and their combined effects. (reading.ac.uk)
  • Dynamic functional connectivity is a recent expansion on traditional functional connectivity analysis which typically assumes that functional networks are static in time. (wikipedia.org)
  • Further in scientific subjects mother or father survey of irritability was dimensionally linked to reduced activation from the anterior cingulate and striatum during irritation. (researchassistantresume.com)
  • In this regard, the work of Paul Ekman, Ph.D., and Richard Davidson, Ph.D., using electroencephalogram recordings while subjects viewed gruesome films indicated asymmetries in activation patterns in the anterior regions of the left and right hemispheres (Davidson et al. (psychiatrictimes.com)
  • 1990). In particular, positive affect (indexed by facial expression) was associated with left-sided anterior activation, while negative affect was associated with right-sided activation (Davidson et al. (psychiatrictimes.com)
  • The proposed framework evaluates whether pairs of spatial networks (e.g., visual network and auditory network) are capable of subject identification and assesses the spatial variability in different network pairs' predictive power in an extensive whole-brain analysis. (biorxiv.org)
  • Ischemia is not an independent predictive factor of chronic renal failure after partial nephrectomy in a solitary kidney in patients without pre-operative renal insufficiency. (univ-rennes.fr)
  • The new criteria for diagnosing prodromal AD assume that, to increase the predictive value of the MCI, in addition to a defect of delayed recall there must also be the presence of abnormal biomarkers, investigating structural and molecular neuroimaging and cerebrospinal fluid (CSF) analysis of amyloid-β or tau proteins. (iospress.com)
  • The aim of this study was to investigate shared and disorder-specific brain activation abnormalities during sustained attention in the two disorders. (omicsdi.org)
  • Analysis of dynamic functional connectivity has shown that far from being completely static, the functional networks of the brain fluctuate on the scale of seconds to minutes. (wikipedia.org)
  • Finally, some functional networks are fleeting enough to only be seen with DFC analysis. (wikipedia.org)
  • Hierarchical Bayesian analysis was used to compare computational modeling parameters between groups.Patient groups shared reduced choice consistency and relied less on reinforcement learning during decision making relative to control subjects, while adolescents with ADHD alone demonstrated increased reward sensitivity. (omicsdi.org)
  • The interaction effect between RHR and physical activity (PA) on cognitive decline was found, and stratification analysis was presented that higher RHR would only show risk effects on cognitive decline in those with physical inactivity (P (bvsalud.org)
  • Bandura's social-cognitive approach and Berkowitz's cognitive-neoassociation analysis posit a role for emotional arousal as an affective tag that may facilitate lasting influences. (psychiatrictimes.com)
  • By comparing phonological versus semantic fluency, higher activation was robustly observed in BA 44. (jneurosci.org)
  • 2004]. In contrast, increased activation in the left IFG was found for semantic functions in adolescents with ASD compared to typically developing (TD) adolescents [Knaus, 2008]. (fulbright.org.tw)
  • We demonstrate the usefulness of our model which is able to estimate both the neuronal activity and the haemodynamic response function in every voxel of the brain. (ox.ac.uk)
  • Performance and brain activation were compared between groups. (omicsdi.org)
  • The findings suggest that attention performance in the two disorders is underpinned by disorder-specific activation patterns. (omicsdi.org)
  • Andrzejak RG, David O, Gnatkovsky V, Wendling F, Bartolomei F, Francione S, Kahane P, Schindler K, de Curtis M . Localization of Epileptogenic Zone on Pre-surgical Intracranial EEG Recordings: Toward a Validation of Quantitative Signal Analysis Approaches. (univ-rennes.fr)
  • Additionally we discovered that activation from the PCC was considerably higher for all those scientific subjects acquiring versus not acquiring stimulant medications. (researchassistantresume.com)
  • Hence an alternative solution explanation may be that increased PCC activation was powered simply by subjects who had been prescribed stimulant medication. (researchassistantresume.com)
  • Our analysis on nearly 12,000 unaffected individuals from the UK Biobank study demonstrates that the proposed approach can discriminate subjects with an accuracy of up to 88% for a single network pair on the test set (best model, after several runs), and 82% average accuracy at the subcortical domain level, notably the highest average domain level accuracy attained. (biorxiv.org)
  • Here, we used functional Magnetic Resonance Imaging (fMRI) to investigate the effects the selective dopamine D(3) receptor antagonist GSK598809 on brain activation to food images in a sample of overweight and obese binge-eating subjects. (exeter.ac.uk)
  • 5 subjects, reviews, meta-analyses, editorials, animal research and research not pertaining to SRC. (bmj.com)
  • However, developing hypotheses about viewing violence and brain activation needs to start with research on physiological arousal (e.g. (psychiatrictimes.com)
  • The resulting brain activation can be graphically represented by color-coding the strength of activation across the brain or the specific region studied. (theinfolist.com)
  • Here, we resolve this apparent controversy by showing that the conflicting findings can be accounted for when considering the influence of task demands and individual ability on resulting functional magnetic resonance imaging activation patterns. (jneurosci.org)
  • While these email address details are tough to interpret additional given connections with feeling temperament and scientific position they hint at the chance of differential praise function in irritable scientific children which really is a analysis region ripe for potential investigation. (researchassistantresume.com)
  • Unlike structural connectivity which looks for physical connections in the brain, functional connectivity is related to similar patterns of activation in different brain regions regardless of the apparent physical connectedness of the regions. (wikipedia.org)
  • The findings suggest replicable neuroimaging features associated with major depression, beyond the transdiagnostic effects reported in previous meta-analyses, and support a continued research focus on the subgenual cingulate and other selected regions' role in depression. (psychiatryonline.org)
  • Jag är även docent vid Karolinska Institutet (KI), anknuten till Aging Research Center vid KI, affilierad till Stockholm University Brain Imaging Centre (SUBIC), samt har en fakultetsposition vid Digital Futures som är ett tvärvetenskapligt forskningscentrum lokaliserat till Kungliga Tekniska Högskolan. (su.se)
  • In addition to showing transient brain states, DFC analysis has shown a distinct hierarchical organization of the networks of the brain. (wikipedia.org)
  • The defined window is then moved a certain number of scans forward in time and additional analysis is performed. (wikipedia.org)
  • required on transforms and concept increased in the heart of group time individuals for flawless application work themes, this counseling can sometimes make the therapeutic progressive voxel of specialties of other association depots. (stefan-johannson-dk.de)
  • Study hypotheses will be tested using the treatment-by-time interaction assessed in multiple general linear models with repeated measures analyses in an intent-to-treat analysis. (biomedcentral.com)
  • Structural differences between bilinguals and monolinguals revealed by subcortical shape analysis. (reading.ac.uk)
  • The outcomes of independent examples Rifampin t-tests revealed a substantial group difference for the Being successful Rifampin condition [activation from the ACC and reported elevated arousal during detrimental feedback. (researchassistantresume.com)
  • Task functional MRI (fMRI) has been widely employed to assess brain activation and networks. (elsevierpure.com)
  • Adolescents with ASD showed reduced left IFG activation as compared to TD adolescents. (fulbright.org.tw)
  • Undue body image concerns are another major pathological feature of BN and hence brain activation patterns associated with the processing of visual presentations of one's own and other women's bodies have been studied using various fMRI paradigms. (biomedcentral.com)