• Our initial investigation commenced with the reaction of unactivated 1,5-enyne 1a with commercially available tosylhydrazide ( 2a ) under air conditions using di- tert -butyl peroxide (DTBP) in 1,2-dichloroethane (DCE) at 120 °C. Theoretically, this reaction may undergo two different pathways to deliver arylsulfonylated indenes 3a and naphthalenes 4a , respectively ( via pathways shown in Scheme 2b and c ). (rsc.org)
  • Pyrolysis gas chromatography-mass spectrometry demonstrated that the organic matter in pyrolysates comprises mainly alkyl-aromatic hydrocarbons (alkyl-benzenes, alkyl-indenes, alkyl-naphthalenes, etc.) and n-alkanes. (gsj.jp)
  • from the structures of 19a and 22b determined by X-ray crystallography, it follows that the indenes 19 and 21 are formed preferentially with retention of configuration at the spiro carbon atom and the naphthalenes 20 and 22 with inversion. (hw.ac.uk)
  • Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B. (nih.gov)
  • Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis. (nih.gov)
  • In this study, the synthesis and biological evaluation of heteroaryl-substituted dihydronaphthalenes and indenes (1-16) is described. (nih.gov)
  • A highly efficient, direct and multicomponent route for the synthesis of indenes is reported herein. (rsc.org)
  • EN ) Liddle, J. and J.W. Huffman, Enantioselective synthesis of 11-hydroxy-(1 ' S,2 ' R)- dimethylheptyl-Delta(8)-THC, a very potent CB1 agonist. (wikipedia.org)
  • In this contribution we describe the synthesis of ferroceno[2,3-a]indenes relevant to the above mentioned applications. (mdpi.com)
  • A highly stereoselective [Pd]‐catalyzed arylation of tert‐alkenols, is presented and applied to the synthesis of indenes using intramolecular Friedel-Crafts alkylation sequence. (chemistryviews.org)
  • in 2015, during which he completed a Masters thesis on palladium-catalyzed annulation reactions for the synthesis of fulvenes and indenes under the guidance of Prof. Jayanta K. Ray at the Indian Institute of Technology, Kharagpur. (tamu.edu)
  • 3) A calcium-catalyzed synthesis of cyclopenta[b]thiophenes and indenes via dehydrative Nazarov-type electrocyclizations of alkenyl (hetero)aryl carbinols. (gatech.edu)
  • On the basis of a proposed pharmacophore for the cannabimimetic indoles, a series of pyrroles and indenes were developed, some of which are potent cannabinoids. (eurekaselect.com)
  • Two groups have described cannabimimetic indenes, which have been employed as rigid models for the receptor interactions of cannabimimetic indoles with the CB1 receptor. (eurekaselect.com)
  • Huffman JW (2009) Cannabimimetic indoles, pyrroles, and indenes: structure-activity relationships and receptor interactions. (wikipedia.org)
  • Known as (1-pentyl-3-(1-naphthoyl)indole), or the more proper IUPAC name of Naphthalen-1-yl-(1-pentylindol-3-yl)methanone, JWH-018 is one of over 100 indoles, pyrroles, and indenes synthesized by the Huffman laboratory to develop cannabimimetics, drugs that mimic the effect of cannabinoids such as THC. (cenblog.org)
  • It is also used to prepare highly substituted indenes using palladium-catalyzed carboannulation. (alfa.com)
  • The presence of four indans, tetralin, five indenes and two dihydronaphthalenes was established. (astm.org)
  • 11. A coating composition of claim 1 wherein said substituted phenol is a phenol substituted with a material selected from the group consisting of indenes, vinylidene aromatics, cyclopentadienes, dicyclopentadienes, nonenes, octenes, terpenes and mixtures thereof. (google.es)
  • Of the fuel systems studied, the greatest reaction was observed in blends containing methyl- and ethyl-substituted indenes. (cdc.gov)