• The incremental cost-effectiveness ratio (ICER) is a statistic used in cost-effectiveness analysis to summarise the cost-effectiveness of a health care intervention. (wikipedia.org)
  • With the number of cost-effectiveness studies rising, it is possible for a cost-effectiveness ratio threshold to be established in other countries for the acceptance of reimbursement or formulary listing at a given price. (wikipedia.org)
  • What is the incremental cost-effectiveness ratio (ICER)? (wikipedia.org)
  • These images are a random sampling from a Bing search on the term "Incremental Cost Effectiveness Ratio. (fpnotebook.com)
  • Davis, W 2010, ' Compared with glyburide, sitagliptin associated with incremental cost-effectiveness ratio of $169572 per QALY and exenatide with $278935 per QALY as second-line treatment in adult diabetics in the USA ', Evidence - Based Medicine (English Edition): for primary care and internal medicine , vol. 15, no. 2, pp. 40-41. (edu.au)
  • We propose using the results of pharmacodynamic Monte Carlo simulation studies as a surrogate marker for potential efficacy of antibiotic dosage regimens and applying these end points to the calculation of an incremental cost-effectiveness ratio (ICER). (formularywatch.com)
  • Cost-effective analysis, and specifically the incremental cost-effectiveness ratio (ICER), is a particularly useful type of pharmacoeconomic analysis because it determines the monetary cost that would be incurred to obtain 1 additional unit of measure (eg, how much more is spent to achieve 1 additional cure) with a more expensive, but more effective, drug. (formularywatch.com)
  • The model included clinical data from Basque hospitals and the literature and was processed by deterministic and probabilistic analysis to calculate the incremental cost-effectiveness ratio (ICER), the cost-effectiveness plane, the acceptability curve and the expected value of perfect information. (isciii.es)
  • El modelo incluyó datos clínicos de hospitales vascos y la literatura para calcular la ratio de coste-efectividad incremental (RCEI) mediante análisis determinista y probabilístico, el plano coste-efectividad, la curva de aceptabilidad y el valor esperado de la información perfecta. (isciii.es)
  • In designing an economic evaluation, the important questions to resolve are: which costs should be included and which outcome measures are most appropriate for estimating the cost-effectiveness ratio? (repec.org)
  • Outcome measures included symptom free days (SFD), quality adjusted life years (QALY), direct costs, productivity losses, and incremental cost effectiveness ratio (CER), measured from the employer and the societal perspectives. (bmj.com)
  • The incremental cost-effectiveness ratio was $196,320 (in 2010 dollars) per life saved compared with a supportive care strategy. (sciencedaily.com)
  • Likewise, adapted incremental cost and incremental cost-effectiveness ratio (ICER) were around 3.5-8 times higher than the values reported in the Indian reference study. (bmj.com)
  • The primary outcome measure is the incremental cost-effectiveness ratio. (biomedcentral.com)
  • The incremental cost-effectiveness ratio was expressed as cost per quality-adjusted life-years gained. (eur.nl)
  • This resulted in an average incremental cost-effectiveness ratio over all simulations of €3,948 per quality-adjusted life-years gained and was below a willingness-to-pay threshold of €25,000 per quality-adjusted life-years gained in 86.9% of simulation runs. (eur.nl)
  • The incremental cost-effectiveness ratio was −£2758/QALY (2.5% and 97.5%: −38 739.5, 34 024.2. (bmj.com)
  • In addition the net costs and the incremental cost-effectiveness ratio (ICER) were evaluated. (univalle.edu.co)
  • Recent data suggest an incremental cost effectiveness ratio of $2500-$4500 per quality-adjusted life year gained. (cdc.gov)
  • In the two subregions, the incremental cost-effectiveness ratio of engineering control s (EC) looks most attractive. (cdc.gov)
  • The model estimated the expected costs in 2022 US dollars, expected quality-adjusted life years (QALYs), incremental cost-effectiveness ratio (ICERs), and expected net monetary benefit over 20 years. (medscape.com)
  • The incremental cost-effectiveness ratio of the intervention ranged from $10,995 to $33,319 per QALY gained when compared with usual care. (cdc.gov)
  • cost-effectiveness ratio (ICER) of USD 8,990 per QALY gained. (bvsalud.org)
  • The incremental cost effectiveness ratio (ICER) was used to perform the cost effectiveness analysis.Results :There were 248 patients enrolled in the study. (bvsalud.org)
  • A common application of the ICER is in cost-utility analysis, in which case the ICER is synonymous with the cost per quality-adjusted life year (QALY) gained. (wikipedia.org)
  • If for a given intervention the ICER is above this threshold it will be deemed too expensive and thus should not be funded, whereas if the ICER lies below the threshold the intervention can be judged cost-effective. (wikipedia.org)
  • As health care costs have continued to rise, many new clinical trials are attempting to integrate ICER into results to provide more evidence of potential benefit. (wikipedia.org)
  • Many people feel that basing health care interventions on cost-effectiveness is a type of health care rationing and have expressed concern that using ICER will limit the amount or types of treatments and interventions available to patients. (wikipedia.org)
  • In sensitivity analyses, the ICER for treating all stages vs treating stages F3 and F4 was most sensitive to cohort age, drug costs, utility values in stages F1 and F2, and percentage of patients eligible for 8-week therapy. (balloon-juice.com)
  • The ICER is determined by calculating the differences in the costs and effects of both intervention and control groups and dividing the former by the latter. (repec.org)
  • This paper reports the results of investigations into the two questions which need to be addressed prior to undertaking a formal economic evaluation of the CHOOSE HEALTH program: i) what costs should be included and ii) which measures of outcome are suitable for estimating an ICER in this context. (repec.org)
  • The mean incremental cost and ICER were 2.5 times and 1.5 times higher, respectively, than the Indian reference study values. (bmj.com)
  • Results The ICER resulting from the fixed-effect meta-analysis, adjusted for clustering and differences in baseline characteristics, showed that SDD significantly reduced in-hospital mortality (adjusted absolute risk reduction 0.0195, 95% CI 0.0050 to 0.0338) with no difference in costs (adjusted cost difference €62 in favour of SDD, 95% CI -€1079 to €935). (bmj.com)
  • Compared with rifabutin triple therapy, vonoprazan triple therapy had a higher expected cost ($1172 vs $1048) and expected QALY (14.262 vs 14.256), yielding an ICER of $22,573 per QALY. (medscape.com)
  • Cost-effectiveness ratios are expressed as cost (in thousands of dollars) per additional case of PID prevented compared to the baseline strategy. (cdc.gov)
  • Across countries, cost-effectiveness ratios ranged from US$792 (482-1,785) in Swaziland to US$1,257 (767-2,276) in Botswana. (plos.org)
  • Assessing outcomes over a 10-y period focuses on the near-term consequences of Xpert adoption, but the cost-effectiveness results are conservative, with cost-effectiveness ratios assessed over a 20-y time horizon approximately 20% lower than the 10-y values. (plos.org)
  • Cost-effectiveness results were presented as incremental cost-effectiveness ratios and incremental net health benefits overall and for low, medium and high pretest likelihood of CHD subgroups. (bmj.com)
  • Incremental cost-effectiveness ratios (ICERs) were calculated for increasing risk score thresholds. (springer.com)
  • The primary outcome was incremental cost-effectiveness ratios (ICERs). (figshare.com)
  • Incremental cost-effectiveness ratios were 667 per exacerbation avoided and 1084 per patient with a relevant improvement on the SGRQ. (ersjournals.com)
  • The authors tracked health and determined incremental cost-effectiveness ratios, or ICERs, over a 50-year analytic horizon. (cdc.gov)
  • Predicted incremental cost-effectiveness ratios were below generally acceptable threshold values. (eur.nl)
  • Finally, the pharmacoeconomic data of the two treatment regimens were compared by calculating their incremental cost- effectiveness ratios. (cancernetwork.com)
  • In both of the two subregions, engineering control s are the most cost effective with ratios varying from 105.89 dollars per healthy year or disability adjusted life year saved in AMROA to approximately 109 dollars in WPROB1. (cdc.gov)
  • The main outcome measures were costs (in Euros), true-positive type 2 diabetic cases, incremental cost-effectiveness ratios (ICERs), third-party payers, and societal perspectives. (diabetesjournals.org)
  • For all patients, cetuximab showed very high (i.e., unfavourable) incremental cost-effectiveness ratios-meaning it was very costly in relation benefits-compared with best supportive care. (ecancer.org)
  • The incremental cost-effectiveness ratios were, however, more favourable for patients whose tumours harboured wild-type KRAS. (ecancer.org)
  • The objective of the study was to assist Israeli policymakers in their efforts to prioritize interventions and develop a national tobacco-control program by calculating cost-effectiveness ratios of interventional modalities known to reduce the smoking-related burden of disease. (who.int)
  • for example, the National Institute for Health and Care Excellence (NICE) adopts a nominal cost-per-QALY threshold of £20,000 to £30,000. (wikipedia.org)
  • In 2009, NICE set the nominal cost-per-QALY threshold at £50,000 for end-of-life care because dying patients typically benefit from any treatment for a matter of months, making the treatment's QALYs small. (wikipedia.org)
  • In 2016, NICE set the cost-per-QALY threshold at £100,000 for treatments for rare conditions because, otherwise, drugs for a small number of patients would not be profitable. (wikipedia.org)
  • Oncotype is a cost-effective intervention from a health system perspective since each QALY gained costs less than 25,000 euros. (isciii.es)
  • Results CMR had the highest estimated QALY gain overall (2.21 (95% credible interval 2.15, 2.26) compared with 2.07 (1.92, 2.20) for NICE and 2.11 (2.01, 2.22) for MPS) and incurred comparable costs (overall £1625 (£1431, £1824) compared with £1753 (£1473, £2032) for NICE and £1768 (£1572, £1989) for MPS). (bmj.com)
  • Overall, CMR was the cost-effective strategy, being the dominant strategy (more effective, less costly) with incremental net health benefits per patient of 0.146 QALYs (−0.18, 0.406) compared with NICE guidelines at a cost-effectiveness threshold of £15 000 per QALY (93% probability of cost-effectiveness). (bmj.com)
  • Economic analyses indicated that PLAN-A did not lead to demonstrable cost-effectiveness in terms of cost per unit change in QALY. (biomedcentral.com)
  • Compared with non-preemptive DDKT, non-preemptive LRKT was not cost-effective at the current Thai willingness-to-pay threshold of $5113/QALY gained. (figshare.com)
  • NMS has an 89% probability of cost-effectiveness at a willingness to pay of £20 000 per QALY. (bmj.com)
  • However, it is unlikely that these differences were captured by the cost-effectiveness outcomes (Incremental cost/QALY). (bl.uk)
  • The overarching aim was to utilise ePAQ trial data, to improve the relevance of the cost-effectiveness outcomes by incorporating process utility into the QALY. (bl.uk)
  • The inclusion of process utility in the ePAQ EEACT moved the intervention from being dominated by the control, to a position where it falls within the willingness-to-pay threshold of £20,000/QALY, indicating its inclusion can impact on cost-effectiveness results. (bl.uk)
  • The incremental cost per major outcomes averted was €6093, and the incremental cost per QALY gained was €94 717. (bmj.com)
  • Vonoprazan triple therapy had the highest expected net monetary benefit and was the most cost-effective at willingness to pay thresholds between $50,000 and $150,000 per QALY, followed by rifabutin triple therapy. (medscape.com)
  • Very cost-effective interventions are those that achieve an increase in QALYs at a relatively low cost (the cost per QALY is less than the per capita GNP, in keeping with the accepted WHO criteria). (who.int)
  • Health outcomes were expressed as quality-adjusted life-years (QALYs), and costs reflected UK pound sterling in 2016-2017. (bmj.com)
  • A 2020 European position paper, in keeping with other national and international guidelines, 2 3 stated that "comprehensive cardiac rehabilitation has been recognised as the most cost effective intervention to ensure favourable outcomes across a wide spectrum of cardiovascular disease. (bmj.com)
  • Conclusions and Relevance In this simulated model, treating HCV infection at early stages of fibrosis appeared to improve health outcomes and to be cost-effective but incurred substantial aggregate costs. (balloon-juice.com)
  • In the final section (section 4), a cost model is presented and the implications of the outcomes used in the initial trials of the effectiveness are discussed in relation to designing a prospective economic evaluation of the CHOOSE HEALTH program. (repec.org)
  • We conducted sensitivity analyses on key programme costs and outcomes by estimating a best case and worst case scenario for each intervention strategy. (bmj.com)
  • A decision tree and Markov model were used to evaluate and compare the lifetime costs and health-related outcomes of LRKT with those of 2 KT strategies: non-preemptive LRKT and non-preemptive deceased donor KT (DDKT). (figshare.com)
  • Substituting tiotropium for ipratropium in chronic obstructive pulmonary disease patients offers improved health outcomes and is associated with increased costs of 180 per patient per year. (ersjournals.com)
  • The main outcomes were total costs and quality-adjusted life-years. (eur.nl)
  • Long-term economic evaluation suggested NMS may deliver better patient outcomes and reduced overall healthcare costs than normal practice, but uncertainty around this finding is high. (bmj.com)
  • This study models the long-term clinical and cost outcomes of two factor VIII (FVIII) products using a pharmacokinetic (PK) simulation model in a Chinese population. (biomedcentral.com)
  • Secondary outcomes collected at all timepoints include overall survival, response-rate and duration and safety, with quality of life and cost-effectiveness outcomes collected 3-monthly for up to 18-months. (biomedcentral.com)
  • We forecasted disease outcomes, quality-adjusted life years (QALYs) gained, and lifetime costs associated with attaining different hemoglobin A1c (A1c) levels. (cdc.gov)
  • NMS generated a mean of 0.04 (95% CI −0.01 to 0.13) more QALYs per patient, with mean reduction in lifetime cost of −£113.9 (−1159.4, 683.7). (bmj.com)
  • BAY 81-8973 resulted in both cost savings and a gain in quality adjusted life years (QALYs) compared to rAHF-PFM. (biomedcentral.com)
  • The mean incremental cost of depression treatment in this program was $357. (nih.gov)
  • Pharmacoeconomic analyses are useful in measuring the relevant costs and consequences of competing drug regimens in order to support formulary decision-making. (formularywatch.com)
  • Sensitivity analyses were performed to assess the robustness of the estimated cost-effectiveness. (sciencedaily.com)
  • Uncertainty was explored using sensitivity analyses and cost-effectiveness acceptability curves. (bmj.com)
  • In an accompanying editorial, Robin Yabroff, Ph.D., of the Division of Cancer Control and Population Science, National Cancer Institute in Bethesda, Md., and Deborah Schrag, M.D., of the Dana Farber Cancer Institute in Boston, note that these findings help raise important questions about how cost-effectiveness analyses inform coverage decisions. (ecancer.org)
  • Sensitivity analyses were conducted to assess the extent to which our results were dependent on assumptions related to program effectiveness, projected years, discount rates, and costs. (cdc.gov)
  • Public health interventions such as those delivered at schools, worksites and other community settings were not covered as the literature does not provide sufficient information to calculate generalizable cost-utility analyses. (who.int)
  • It is defined by the difference in cost between two possible interventions, divided by the difference in their effect. (wikipedia.org)
  • Although risk scores to predict type 2 diabetes exist, cost-effectiveness of risk thresholds to target prevention interventions are unknown. (springer.com)
  • A risk score threshold ≥ 5% together with elevated FPG would also allow targeting interventions cost-effectively. (springer.com)
  • aHTA may be used for 'topic prioritisation' within the overall HTA process, whereby interventions which are highly cost-ineffective, can be directly ruled out, thus saving time and resources for conducting full HTA for interventions that are not well studied or where evidence is inconclusive. (bmj.com)
  • The cost effectiveness of occupational health interventions: prevention of silicosis. (cdc.gov)
  • The failure to recognize occupational health as an economic phenomenon limits the effectiveness of interventions ostensibly designed to prevent disease and injury. (cdc.gov)
  • To evaluate the cost effectiveness of specific interventions for the prevention of occupationally induced silicosis, we have used the simulation models based on the generalized cost-effectiveness analysis (GCEA) developed by the WHO-CHOICE initiative for two representative subregions namely AMROA (Canada, United States of America), and WPROB1 (China, Korea, Mongolia). (cdc.gov)
  • However, this study shows that even when restricted to metastatic colorectal cancer patients with wild-type KRAS tumours, the cost-per quality adjusted life year gained for cetuximab therapy compared to best supportive care exceeds commonly accepted thresholds of $50,000 to $100,000 per quality adjusted life year that signify "good value" health care interventions. (ecancer.org)
  • Although research has analyzed the cost-effectiveness of CHW-based diabetes management interventions delivered in primary care settings (17,18), we know of no cost-effectiveness studies of diabetes self-care interventions that involve CHWs delivering home-based counseling and education. (cdc.gov)
  • Eight cost-saving and 13 very cost-effective interventions were identified. (who.int)
  • Cost-saving interventions are those where the treatment costs averted by the decrease in morbidity exceed the cost of the intervention. (who.int)
  • To provide a wide selection of interventions likely to assist a variety of smokers, a combination of the five non fiscal cost-saving and the top eight very cost-effective interventions listed above could be chosen for implementation. (who.int)
  • We compared the response rate, data agreement, costs, and participants' acceptability of the two methods. (jmir.org)
  • Methods Using UK data for 1202 patients from the Clinical Evaluation of Magnetic Resonance Imaging in Coronary Heart Disease 2 trial, we conducted an economic evaluation to assess the cost-effectiveness of CMR, MPS and NICE guidelines. (bmj.com)
  • Methods Prospective cost analysis of an opportunistic screening programme delivered jointly in three types of healthcare facility in Ireland. (bmj.com)
  • During each iteration, the computer algorithm selects input values from the probability distributions, and calculates the output (e.g., cost per patient successfully treated). (cdc.gov)
  • A willingness-to-pay curve was plotted to reflect the probability of cost-effectiveness of SDD for a range of different values of maximum costs per prevented in-hospital death. (bmj.com)
  • At a willingness-to-pay value of €33 633 per one prevented in-hospital death, SDD had a probability of 90.0% to be cost-effective as compared with SOD. (bmj.com)
  • Conclusion In Dutch ICUs, SDD has a very high probability of cost-effectiveness as compared to SOD. (bmj.com)
  • The net incremental monetary benefit was not statistically significantly different between arms, although the probability of the intervention being cost-effective was above 60%, at policy-relevant thresholds. (nature.com)
  • Además, se valoraron los costos netos y la razón de costo-efectividad incremental (RCEI). (univalle.edu.co)
  • Conclusions CMR-guided care is cost-effective overall and across all pretest likelihood subgroups, compared with MPS and NICE guidelines. (bmj.com)
  • Conclusions Despite higher total costs relative to BMS, EES appeared to be a cost-effective therapy for ST-segment elevation myocardial infarction patients due to their incremental effectiveness. (eur.nl)
  • Conclusions At 26-week follow-up, NMS was unable to demonstrate a statistically significant increase in adherence or reduction in NHS costs, which may be attributable to patient attrition from the study. (bmj.com)
  • Conclusions An opportunistic chlamydia screening programme, as modelled in this study, would be expensive to implement nationally and is unlikely to be judged cost effective by policy makers in Ireland. (bmj.com)
  • Conclusions Universal decolonization is cost-saving, preventing 44% of cases of MRSA colonization and 45% of cases of MRSA infection. (medscape.com)
  • Most economic evaluations involve modelling (a little to a lot) where health effects and related costs are estimated, to arrive at a calculation of value. (sciencebasedmedicine.org)
  • The incremental effectiveness of dantrolene compared with supportive care was 33 more lives saved per year. (sciencedaily.com)
  • Assumptions on screening participation have a major influence on the ordering of strategies in terms of costs and effects. (nih.gov)
  • Results were sensitive to assumptions about sensitisation rate, removal rates, and time to diagnosis, but not to assumptions about therapy costs and disability rates. (bmj.com)
  • Incremental lifetime costs and health effects were estimated from a healthcare perspective. (nih.gov)
  • In health and healthcare, the results can be used to inform clinicians and policy makers about the relative cost-effectiveness of options under consideration [1]. (repec.org)
  • This longitudinal, randomised, controlled trial studied the health and care plan model's impact on healthcare costs, patients' physical functioning and patients' quality of life. (helsinki.fi)
  • ie, costs to prevent one in-hospital death) was calculated by comparing differences in direct healthcare costs and in-hospital mortality of patients treated with SDD versus SOD. (bmj.com)
  • Mean annual healthcare costs including the acquisition cost of the study drugs were 1721 (sem 160) in the tiotropium group and 1,541 (SEM 163) in the ipratropium group (difference 180). (ersjournals.com)
  • The aim of the cost-effectiveness analysis was to compare tiotropium and ipratropium with respect to healthcare utilisation and costs and to relate the difference in cost to the difference in COPD exacerbations and quality of life over a period of 1 yr. (ersjournals.com)
  • A healthcare provider perspective was adopted with respect to costs and included the costs of screening and the costs of complications arising from untreated infection. (bmj.com)
  • The analysis is believed to be the first to report on the cost-effectiveness of vonoprazan- and rifabutin-based regimens as first-line treatments for H pylori infection from the perspective of US healthcare payers. (medscape.com)
  • Therefore, total healthcare costs may be underestimated. (medscape.com)
  • Given current attention to healthcare costs in the U.S., interest in explicitly comparing the costs and benefits of treatment, as performed by Mittmann et al. (ecancer.org)
  • We aimed to assess the potential of CT colonography (CTC) and MR colonography (MRC) in terms of (cost-effectiveness) using the Adenoma and Serrated pathway to Colorectal CAncer model. (nih.gov)
  • This is the first study to assess the cost-effectiveness of MRC screening for CRC. (nih.gov)
  • The purpose of this analysis is to assess the cost-effectiveness of stocking dantrolene in ambulatory surgery centers as recommended by the Malignant Hyperthermia Association of the United States. (sciencedaily.com)
  • It is the first pharmaco-economic analysis of tiotropium, conducted to assess whether the benefits of this new therapy are achieved at reasonable costs. (ersjournals.com)
  • The main objective of this project is to assess the cost-effectiveness of a primary care-based exercise intervention in perimenopausal women. (biomedcentral.com)
  • We sought to assess the cost-effectiveness of EES versus BMS based on the 5-year results of the EXAMINATION trial, from a Spanish health service perspective. (eur.nl)
  • This prospective cost-effectiveness analysis was performed alongside two 1‐yr randomised, double-blind clinical trials in the Netherlands and Belgium. (ersjournals.com)
  • The cost-effectiveness analysis was performed alongside the ipratropium-controlled clinical trials reported by Vincken etal 5 . (ersjournals.com)
  • This cost-effectiveness analysis was performed alongside two randomised controlled, double-blind, double-dummy, parallel group trials comparing 18 µg tiotropium inhalation capsules administered once daily in the morning via the HandiHaler® device with ipratropium 2 puffs of 20 µg administered four times daily via the metered dose inhaler (MDI) in patients with airway obstruction due to COPD 5 . (ersjournals.com)
  • Incremental cost-effectiveness analysis was performed using an existing dynamic modelling framework to compare screening to a control of no organised screening. (bmj.com)
  • Objective To determine the cost-effectiveness of selective digestive decontamination (SDD) as compared to selective oropharyngeal decontamination (SOD) in intensive care units (ICUs) with low levels of antimicrobial resistance. (bmj.com)
  • Objective To quantify randomness and cost when choosing health and medical research projects for funding. (bmj.com)
  • Objective To examine the effectiveness and cost-effectiveness of the community pharmacy New Medicine Service (NMS) at 26 weeks. (bmj.com)
  • Objective The objective of this study was to estimate the cost and cost-effectiveness of opportunistic screening for Chlamydia trachomatis in Ireland. (bmj.com)
  • Objective To create a national policy model to evaluate the projected cost-effectiveness of multiple hospital-based strategies to prevent methicillin-resistant Staphylococcus aureus (MRSA) transmission and infection. (medscape.com)
  • The objective of our study was to estimate the long-term cost-effectiveness of a lifestyle modification program led by community health workers (CHWs) for low-income Hispanic adults with type 2 diabetes. (cdc.gov)
  • In addition, we will conduct a cost effectiveness analysis from a health system perspective. (biomedcentral.com)
  • In this study, Nicole Mittmann, of the HOPE Research Centre Sunnybrook Health Sciences Centre, in Toronto, and colleagues used prospectively collected resource utilization and health utility data from that trial to conduct a cost-effectiveness analysis to determine the costs per life-year gained and costs per quality-adjusted life-year gained. (ecancer.org)
  • Using a Markov model, Yunusa and colleagues estimated the cost-effectiveness of five pre-packaged or co-formulated H pylori eradication regimens: clarithromycin triple therapy, bismuth quadruple therapy, vonoprazan dual therapy, vonoprazan triple therapy, and rifabutin triple therapy. (medscape.com)
  • Cost-effectiveness of introducing bedaquiline in MDR-TB regimens - an exploratory analysis, Anna Vassal , London School of Hygiene and Tropical Medicine, London, United Kingdom. (bvsalud.org)
  • the advantages of this approach are that i) prospective, accurate data can be collected on costs and effects and ii) appropriate outcome measures for use in economic evaluation can be chosen. (repec.org)
  • Main outcome measures The proportion of grant proposals that were always, sometimes, and never funded after accounting for random variability arising from differences in panel members' scores, and the cost effectiveness of different size assessment panels. (bmj.com)
  • The introduction of the Heptavalent Pneumococcal Conjugate Vaccine in populations of high risk is highly cost effective in Colombia. (univalle.edu.co)
  • Cost and clinical data were obtained from adult patients who underwent KT at Siriraj Hospital, Mahidol University, Thailand. (figshare.com)
  • Research Department, Institute for Clinical Effectiveness and Health Policy (IECS). (bvsalud.org)
  • Uniject research contract between the Institute for Clinical was cost-saving or very cost-effective in almost all countries. (bvsalud.org)
  • Based on modeled head-to-head comparisons, differences in PK-properties between BAY 81-8973 and rAHF-PFM result in a reduced number of bleeding events, leading to reduced costs and increased quality of life for BAY 81-8973. (biomedcentral.com)
  • Differences between treatments in terms of consumption of resources and associated costs will be tested for statistical significance. (cancernetwork.com)
  • Given the fundamental influence of HIV on TB dynamics and intervention costs, care should be taken when interpreting the results of this analysis outside of settings with high HIV prevalence. (plos.org)
  • We compared the cost effectiveness of the free patch initiative (media and intervention costs) to the pre-initiative service offered to insured and uninsured callers. (bmj.com)
  • Compared to the pre-initiative programme, incremental quitline promotion and intervention costs for the free patch initiative were $86 (range $22-$353) per life year saved. (bmj.com)
  • Research by the University of York identified that the cost per quality adjusted life year for changes in existing NHS expenditure in 2008 was £12,936 leading to concerns new treatments approved by NICE at £30,000 per quality adjusted life year are less cost-effective than spend on existing treatments. (wikipedia.org)
  • All imaging-based strategies were cost-effective compared with no screening. (nih.gov)
  • Compared with three rounds of colonoscopy screening, CTC with five rounds was found to be cost-effective in an incremental analysis of imaging strategies. (nih.gov)
  • When taking FIT screening as the reference, imaging is not cost-effective. (nih.gov)
  • Intervening in those with ≥ 7% diabetes risk based on the GDRS or ≥ 9% on the ARIC 2009 score would be cost-effective. (springer.com)
  • It is not cost effective for most insurers to pay $80,000 for gains that will occur when the patient is no longer covered by that insurer. (balloon-juice.com)
  • Experts say storing the drug dantrolene at ambulatory surgical centers will save lives and is very cost effective. (sciencedaily.com)
  • Our study indicates that requiring ambulatory surgery centers to stockpile Dantrolene as recommended by Malignant Hyperthermia Association of the United States (MHAUS) is a cost-effective measure for treating malignant hyperthermia -- an infrequent but potentially fatal complication. (sciencedaily.com)
  • The results of this analysis suggest that stocking dantrolene for the treatment of MH in ambulatory surgery centers as recommended by the Malignant Hyperthermia Association of the United States is cost-effective when compared with the estimated values of statistical life used by U.S. regulatory agencies. (sciencedaily.com)
  • Before deciding CAM is cost-effective, it is important to determine if is just effective. (sciencebasedmedicine.org)
  • Are complementary therapies and integrative care cost-effective? (sciencebasedmedicine.org)
  • Compared to the pre-initiative programme, the free patch initiative was a highly cost effective strategy for increasing quitting in the population. (bmj.com)
  • The intervention designed is feasible and if it proves to be clinically and cost effective, it can be easily transferred to other similar contexts. (biomedcentral.com)
  • Background Use of everolimus-eluting stents (EES) has proven to be clinically effective and safe in patients with ST-segment elevation myocardial infarction but it remains unclear whether it is cost-effective compared to bare-metal stents (BMS) in the long-term. (eur.nl)
  • In addition, FH cascade testing strategies are cost-effective . (cdc.gov)
  • To the extent that this analysis can be generalized across other subregions, it suggests that engineering control programs would be cost effective in both developed and developing countries for reducing silica exposure to save lives. (cdc.gov)
  • VHA staff provide high-quality care to nine million patients that is better coordinated and more cost effective than in the private sector. (pnhp.org)
  • A new analysis finds that vonoprazan triple therapy (Voquezna) is the most cost-effective first-line regimen to eradicate Helicobacter pylori infection in the United States. (medscape.com)
  • Rifabutin triple therapy (Talicia) is the second most cost-effective strategy for H pylori eradication, followed in order of decreasing cost-effectiveness by vonoprazan dual therapy, bismuth quadruple therapy, and clarithromycin triple therapy. (medscape.com)
  • Because rifabutin triple therapy was predicted to cost less and was more effective than clarithromycin triple therapy, bismuth quadruple therapy, and vonoprazan dual therapy, it dominated all treatment strategies - except for vonoprazan triple therapy. (medscape.com)
  • Because the rifabutin-based regimen was more cost-effective than all but vonoprazan triple therapy, it has a potential role as an alternative first-line treatment. (medscape.com)
  • Rifabutin triple therapy and vonoprazan dual therapy would need to be considerably discounted (by 15%-43% and by 44%-85%, respectively), to be cost-effective at commonly used cost-effectiveness thresholds. (medscape.com)
  • Cite this: Vonoprazan Triple Therapy Most Cost-Effective for H pylori : Study - Medscape - Dec 29, 2022. (medscape.com)
  • UCP+decolonization was more effective than universal decolonization but would cost $2469 per colonization averted and $9007 per infection averted. (medscape.com)
  • The CHW program was cost-effective. (cdc.gov)
  • This study adds to the evidence that culturally sensitive lifestyle modification programs to control diabetes can be a cost-effective way to improve health among Hispanics with diabetes, particularly among those with high A1c levels. (cdc.gov)
  • Accepted: May 3, 2015 zation rates required to make Uniject a cost-effective strategy. (bvsalud.org)
  • to make Uniject a cost-effective strategy ranged from 1.3% in Suriname to 16.2% in Haiti. (bvsalud.org)
  • Today I'm talking with Dr. Kwame Owusu-Edusei about his co-authored article, Cost-effectiveness of Chlamydia Vaccination Programs for Young Women. (cdc.gov)
  • We explored the potential cost and effectiveness of a chlamydia vaccination program, together with chlamydia screening, in young women. (cdc.gov)
  • Additionally, the prevalence of chlamydia, followed by the cost of vaccination, duration of vaccine- conferred immunity and vaccine efficacy had the most impact on the cost-effectiveness measure. (cdc.gov)
  • The cost-utility study was carried out using a discrete event simulation model representing the natural history of breast cancer. (isciii.es)
  • The aim of this study was to apply the framework of cost-effectiveness analysis to identify optimal thresholds of predicted risk from noninvasive diabetes risk scores to target a low-cost community-based intervention. (springer.com)
  • The aim of the study was to study the cost-effectiveness of the health and care plan model compared to standard care practice. (helsinki.fi)
  • The goal of this study was to study if rational pharmacotherapy and self-management support can prevent the decline in physical functioning, the decline in quality of life and the increase in health service use and costs among elderly population. (helsinki.fi)
  • This study examined the effectiveness and cost-effectiveness of the PLAN-A intervention. (biomedcentral.com)
  • Results The adapted cost estimates varied considerably, while adapted quality-adjusted life-years did not differ much, when matched with the Indian reference study. (bmj.com)
  • For intervention I (trastuzumab), adapted absolute costs were 11 and 6 times higher than the costs reported in the Indian reference study for control and intervention arms, respectively. (bmj.com)
  • For intervention II (intensity-modulated radiation therapy), adapted absolute cost was 35% and 12% lower for the comparator and intervention arms, respectively, than the values reported in the Indian reference study. (bmj.com)
  • This study compared the cost-effectiveness of LRKT with those of non-preemptive KT strategies. (figshare.com)
  • Background: This study compares the cost-effectiveness of using an online assessment tool (ePAQ) in advance of a face-to-face (control) versus a telephone (intervention) consultation. (bl.uk)
  • A cost-effectiveness study from the perspective of the third payer was done using a Decision Model. (univalle.edu.co)
  • This study analyzes the cost-effectiveness of a diabetes management intervention for Hispanics delivered in both primary care and home settings. (cdc.gov)
  • Lifetime costs per person for MRC strategies were €60-110 higher than those for CTC strategies with an equal number of screening rounds. (nih.gov)
  • We used a validated Markov-based type 2 diabetes simulation model to evaluate the lifetime cost-effectiveness of alternative thresholds of diabetes risk. (springer.com)
  • A 1% reduction in A1c levels has been correlated with a 21% reduction in vascular complications in people with diabetes, resulting in fewer complications and reduced lifetime health care costs (10). (cdc.gov)
  • We simulated the long-term cost-effectiveness of prevention intervention in high-risk individuals in the context of the US population. (springer.com)
  • Three NICE thresholds for cost-effectiveness: does that make sense? (wikipedia.org)
  • We applied cost-effectiveness analysis to identify optimal thresholds of predicted risk to target a low-cost community-based intervention in the USA. (springer.com)
  • The costs per questionnaire for the text messaging method were much lower than the costs for the face-to-face method: ¥19.7 (US $3.13) versus ¥33.9 (US $5.39) for all questionnaires, and ¥27.1 (US $4.31) versus ¥34.4 (US $5.47) for completed questionnaires. (jmir.org)
  • This event, tied to the high cost of the vaccine, should encourage carefulness in the analysis of the burden of disease of the possible introduction of the vaccine and the balance of the possible benefits of its introduction versus the cost. (univalle.edu.co)
  • Consequently, the findings of this project might help the Health Systems to identify strategies for primary prevention and health promotion as well as to reduce health care requirements and costs. (biomedcentral.com)
  • Our findings reinforce the effectiveness of COVID-19 vaccines in preventing infection in real-world settings. (cdc.gov)
  • The analysis demonstrates the value of a model based approach to evaluate the cost effectiveness of surveillance programmes for isocyanate asthma, and to inform shared decision making among clinicians, patients, employers, and society. (bmj.com)
  • Based on the favourable results of these studies, it is suggested that "if the cost is not prohibitive, bronchodilation in moderate COPD could move to once-daily tiotropium" 8 . (ersjournals.com)
  • Results The average cost per component of screening was estimated at €26 per offer, €66 per negative case, €152 per positive case and €74 per partner notified and treated. (bmj.com)
  • Design Cost-effectiveness analysis using a Markov microsimulation model that simulates the natural history of MRSA acquisition and infection. (medscape.com)
  • Over the life-long time horizon, the EES strategy was €430 more costly than BMS (€8,305 vs. €7,874), but went along with incremental gains of 0.10 quality-adjusted life-years. (eur.nl)
  • From a societal perspective, it is dominant since it provides greater health and is accompanied by cost savings. (isciii.es)
  • Using the example of isocyanate induced asthma, the most commonly reported immune mediated occupational asthma, the authors developed a model based approach to evaluate the costs and benefits of surveillance from both an employer and a societal perspective. (bmj.com)
  • 13.33/SFD) and was cost saving from the societal perspective. (bmj.com)
  • Costs from the societal and employer perspective differed substantially with a more attractive CER from the societal perspective, suggesting opportunities for employer/societal cost sharing. (bmj.com)
  • OGTTs (€4.90 per patient) yielded the lowest costs from the perspective of the statutory health insurance and fasting glucose + OGTT (€10.85) from the societal perspective. (diabetesjournals.org)
  • It represents the average incremental cost associated with 1 additional unit of the measure of effect. (wikipedia.org)
  • The genetic screening program in the Netherlands found that, on average, 3.3 years of life were gained for each new case diagnosed at a cost of $8,700 per year of life gained. (cdc.gov)
  • Vonoprazan triple therapy would result on average in an incremental net benefit of $1655 per patient than clarithromycin triple therapy. (medscape.com)
  • Relative to status quo, Xpert has an estimated cost-effectiveness of US$959 (633-1,485) per disability-adjusted life-year averted over 10 y. (plos.org)
  • As roll-out proceeds, it is essential to understand the potential health impact and cost-effectiveness of diagnostic strategies based on Xpert. (plos.org)
  • Preemptive LRKT is a cost-saving strategy compared with non-preemptive KT strategies. (figshare.com)
  • FIT screening was the dominant screening strategy, leading to most LYG and highest cost-savings. (nih.gov)
  • In October 2004, TPEP initiated a strategy to increase the utilisation and effectiveness of the Oregon tobacco cessation quitline, while reducing television and radio advertising to promote the quitline. (bmj.com)
  • Economic evaluation is the systematic assessment of the costs and consequences of alternative courses of action. (repec.org)
  • Because logistical and financial obstacles impede using large prospective cohort studies, surveillance decisions in occupational settings must often be made without evidence of relative benefits and costs. (bmj.com)
  • In a cohort of 70 thousand children of under 2 years old in situation of high risk, can generate 532 deaths that would produce a little more than 21 thousand Years of Life Lost (YLL) with costs between 7.7 and 13.3 million dollars. (univalle.edu.co)
  • If we vaccinate this same cohort the deaths can be reduced to 355, and the costs of burden of disease would be between 5.7 and 10 million dollars. (univalle.edu.co)
  • Although dust masks (DM) look attractive in terms of cost, the total efficacy is extremely limited. (cdc.gov)
  • The text messaging method had reasonable data agreement and low cost, but a low response rate. (jmir.org)
  • Further research is needed to evaluate effectiveness of measures that can increase the response rate, especially in collecting longitudinal data by text messaging. (jmir.org)
  • Health services utilization and costs were assessed through health plan claims and accounting data. (nih.gov)
  • Using quitline utilisation and cost data from the state, intervention providers and patients, we estimated annual programme use and costs for media promotions and intervention services. (bmj.com)
  • Participation is an important driver of effectiveness and cost estimates. (nih.gov)
  • revised cost-effectiveness estimates incorporating process utility. (bl.uk)
  • However, the additional financial burden would be substantial, including significant increases in costs for treating HIV and MDR-TB. (plos.org)
  • A stepped collaborative care program for depressed primary care patients led to substantial increases in treatment effectiveness and moderate increases in costs. (nih.gov)
  • The authors evaluated the incremental cost-effectiveness of stepped collaborative care for patients with persistent depressive symptoms after usual primary care management. (nih.gov)
  • At base-case drug prices, treating 50% of all eligible US patients with HCV genotype 1 would cost $53 billion. (balloon-juice.com)
  • time-saving in the i-STAT only group only had an additional net cost of US$3.11 per patient (IECR 0.90).Conclusion Upfront, POC blood tests can be utilised in the resource-constrained EC to manage patients more efficiently by saving time. (bvsalud.org)