• We assessed COVID-19 disease severity against circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants during 3 periods of interest based on predominance of circulating variants. (cdc.gov)
  • Splenic macrophages from estrogen supplemented mice showed a significant increased in TNF-alpha mRNA expression (eight fold difference compared to the control) but only a mild change in iNOS mRNA levels (2-3 fold difference). (duke.edu)
  • Mild forms of EB improve with age. (medlineplus.gov)
  • Significant differences were found between patients with mild and increased CU severity. (biomedcentral.com)
  • The best practices to reduce severity of concussions, is to be situationally aware. (github.io)
  • How does Dose Impact on the Severity of Food-Induced Allergic Reactions, and Can this Improve Risk Assessment for Allergenic Foods? (ilsi.eu)
  • This paper reviews the current knowledge around the relationship between dose and severity of food-induced allergic reactions and what data are still needed to improve quantitative risk assessment. (ilsi.eu)
  • Food allergic reactions vary in severity. (cdc.gov)
  • Over the course of the COVID-19 pandemic, alcohol-related liver disease has increased in severity, a finding that is likely related to higher consumption of alcohol and reduced care. (medscape.com)
  • Alcohol consumption during the COVID-19 pandemic led to increased morbidity and mortality, specifically in patients that already had underlying liver disease. (medscape.com)
  • Nonalcoholic Fatty Liver Disease: Modulating Gut Microbiota to Improve Severity? (nih.gov)
  • A new Northwestern Medicine study in mice found a widely used class of drugs to treat patients with hypertension, cardiovascular disease and diabetic kidney disease - many of whom are elderly - does not increase the risk of developing a severe and potentially fatal COVID-19 infection, as previously feared. (scienceblog.com)
  • One consequence of hunting that we show in this paper is that it can increase the probability of dying from the disease, Choisy said. (webwire.com)
  • Killing wild animals can also increase the proportion of the population that s susceptible to disease by removing those individuals who have contracted a virus but have developed lifelong immunity as a result of their infection. (webwire.com)
  • The researchers found that compensation and lifelong immunity conferred by a virus interact so that the timing of mating and birth seasons determine whether hunting increases or decreases disease prevalence. (webwire.com)
  • For example, their model shows that in the case of swine fever, a highly infectious disease threatening boars and pigs in Europe, hunting can increase the number of infected individuals by twenty five percent. (webwire.com)
  • 2. We measured neutrophil nitric oxide synthase activity in relation to the level of hepatic dysfunction in patients with liver disease of varying aetiology and severity. (portlandpress.com)
  • Neutrophil activation and NETs were quantified by immunoassays and microscopy and correlated with parasite biomass and disease severity. (tropmedres.ac)
  • In falciparum malaria, neutrophil activation and NET counts positively correlated with parasite biomass (Spearman rho = 0.41, P = .005 and r2 = 0.26, P = .002, respectively) and were significantly increased in severe disease. (tropmedres.ac)
  • Gut Microbiota and COVID-19: Potential Implications for Disease Severity. (news-medical.net)
  • Previous studies show that low birth weight is associated with an increased risk of later maternal cardiovascular disease (CVD). (ki.se)
  • Researchers at Karolinska Institutet examined the association between severity of preterm birth, fetal growth restriction, and later maternal incident hospitalization or death from coronary heart disease, heart failure, and cerebrovascular events taking measured potential confounders into account. (ki.se)
  • During the 2009 H1N1 pandemic, as well as during interpandemic periods, women in the third trimester of pregnancy were at increased risk for severe disease, such as disease requiring admission to an intensive care unit or resulting in death, as compared with women in an earlier stage of pregnancy. (wikipedia.org)
  • An outbreak is a sudden increase in the incidence of disease in a defined location. (medscape.com)
  • Both children and adults with atopic dermatitis have an increased risk of inflammatory bowel disease (IBD), according to a population-based cohort study. (medpagetoday.com)
  • Breaking it down by subtype, kids had an increased risk of Crohn's disease (HR 1.74, 95% CI 1.54-1.97), but only those with severe atopic dermatitis had an increased risk of ulcerative colitis (HR 1.65, 95% CI 1.02-2.67), whereas adults had increased risks for both Crohn's (HR 1.36, 95% CI 1.26-1.47) and ulcerative colitis (HR 1.32, 95% CI 1.24-1.41), the authors detailed in JAMA Dermatology . (medpagetoday.com)
  • For instance, in children, incidence rates for IBD and Crohn's disease were higher across atopic dermatitis severity groups (range 0.18-0.95 for IBD and 0.10-0.91 for Crohn's) compared with controls (range 0.15-0.16 for IBD and 0.07-0.08 for Crohn's). (medpagetoday.com)
  • Severe atopic dermatitis was associated with the highest increased risks of IBD (HR 2.27, 95% CI 1.96-2.64), Crohn's disease (HR 3.50, 95% CI 2.91-4.20), and ulcerative colitis (HR 2.40, 95% CI, 2.00-2.88) in adults. (medpagetoday.com)
  • Although an increased prevalence of IBD has been observed with AD, others have found an association among adults only and not children ," the authors noted, adding that studies looking at ulcerative colitis and Crohn's disease in patients with atopic dermatitis "have shown incongruent findings . (medpagetoday.com)
  • Legumes-rich diet lowers cardiovascular disease risk, improves heart health. (asianage.com)
  • This may manifest as changes in viral behaviour, such as transmission, disease severity, immune evasion or vaccine efficacy, and may also affect diagnostic sensitivity. (mja.com.au)
  • Although incidence of malignant mesothelioma has gradually declined in the United States, continued use of and exposure to asbestos around the world has resulted in increasing global rates of this aggressive disease. (merck.com)
  • Nevertheless, APR-associated proteins have not been well characterized as potential biomarkers of the disease severity. (biomedcentral.com)
  • Nevertheless, apart from IL-6 and C-reactive protein (CRP), other APR-associated proteins have not been well characterized as potential biomarkers of the disease severity [ 1 - 7 ]. (biomedcentral.com)
  • In patients with symptomatic malaria, neutrophil activation and NET counts were increased in all 3 Plasmodium species. (tropmedres.ac)
  • There is a decreasing susceptibility to malaria with increasing parity, probably due to immunity to pregnancy-specific antigens. (wikipedia.org)
  • The effect of warming-induced vapour pressure deficit (VPD) increases on boreal ET remains poorly understood because peatlands are not specifically represented as plant functional types in Earth system models. (nature.com)
  • To date, clinical guidelines recommend a weight loss goal of 7%-10% to improve features of nonalcoholic fatty liver diseases. (nih.gov)
  • Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19 has been remarkably unpredictable in its clinical severity. (news-medical.net)
  • Sadra Rezakhaniha, from the Islamic Azad University Science and Research Branch Faculty of Basic Sciences in Tehran, Iran, and colleagues investigated the effect of caffeine restriction on the improvement and severity of PMNE in a randomized clinical trial involving 534 children aged 6 to 15 years. (msdmanuals.com)
  • Methods: We performed a retrospective epidemiological study concerning the incidence and severity of clinical cases of coccidioidomycosis at a naval base located in an endemic area in California. (usuhs.edu)
  • Among the GBCC's priorities are creating a large and diverse patient database, launching clinical trials at multiple sites throughout the world and sharing information ― all initiatives that will impact patient outcomes and improve care for those with bladder cancer. (baptisthealth.net)
  • The ESI is a novel clinical marker of emphysema severity that is associated with respiratory death specifically. (lu.se)
  • Other multi-joint resistance exercises that work your major muscle groups may also help increase your testosterone levels provided you follow the high-volume, moderate-to-high-intensity protocol. (livestrong.com)
  • There have been concerns by the medical community worldwide that the drugs - ACE inhibitors and angiotensin receptor blockers (ARB) - might have caused an increase in ACE2, the main receptor for SARS-CoV-2, which could possibly increase the risk for this infection and its severity. (scienceblog.com)
  • This study supports the concept that there is no increased risk for COVID-19 infection by using ACE inhibitors and angiotensin receptor blockers," said Daniel Batlle, the Earle, del Greco, Levin Professor of Medicine at Northwestern University Feinberg School of Medicine and a Northwestern Medicine nephrologist. (scienceblog.com)
  • In unadjusted analyses, care fragmentation, public insurance and African-American race independently resulted in an increased likelihood that a patient would experience a severe infection. (the-rheumatologist.org)
  • The risk of gut dysbiosis has been shown to increase during SARS-CoV-2 infection, as well as post-acute COVID sequelae (PASC), the latter of which is more commonly known as 'long COVID. (news-medical.net)
  • Primary herpes simplex infection, when occurring in pregnant women, has an increased risk of dissemination and hepatitis, an otherwise rare complication in immunocompetent adults, particularly during the third trimester. (wikipedia.org)
  • Over the long term, pollution is linked to increase in cardiovascular and lung diseases, which are in turn associated with more severe COVID-19 symptoms, the researchers said. (eastmojo.com)
  • Mothers who deliver low-birth weight infants are at increased risks of cardiovascular diseases (CVD) later in life. (ki.se)
  • If primary cardiovascular prevention measures are undertaken in women with a history of a preterm or small-for-gestational age birth, it might lower their CVD risk and improve the outcome of the next pregnancy. (ki.se)
  • Exposure to air pollutants, in particular fine particles (PM2.5) and nitrogen dioxide (NO2), increased the risk of hospitalisation in COVID-19 patients by up to 30 percent, even for the fully vaccinated, according to a study. (eastmojo.com)
  • These findings are important because they show that, while COVID-19 vaccines are successful at reducing the risk of hospitalisation, people who are vaccinated and exposed to polluted air are still at increased risk for worse outcomes than vaccinated people not exposed to air pollution," said Anny Xiang, study author and a senior research scientist at KPSC. (eastmojo.com)
  • The team found that among 30,912 people who were unvaccinated, high short-term PM2.5 exposure increased the risk of COVID-19 hospitalisations by 13 per cent, while long-term exposure increased the risk by 24 per cent. (eastmojo.com)
  • As a result, many efforts have been made to determine the factors that increase an individual's risk of severe or fatal COVID-19. (news-medical.net)
  • Earlier studies also indicate that preterm delivery (ie, before 37 weeks) may be associated with an increased maternal CVD risk. (ki.se)
  • There are several potential risk factors or causes to this increased risk: An increased immune tolerance in pregnancy to prevent an immune reaction against the fetus. (wikipedia.org)
  • Young maternal age and increases the risk. (wikipedia.org)
  • Severe and disseminated coccidioidomycosis has been reported to occur in increased frequency in pregnant women in several reports and case series, but subsequent large surveys, with the overall risk being rather low. (wikipedia.org)
  • In fully adjusted models, kids with atopic dermatitis had a 44% increased risk of IBD (HR 1.44, 95% CI 1.31-1.58), while adults had a 34% increased risk (HR 1.34, 95% CI 1.27-1.40) compared with controls without atopic dermatitis, reported Joel M. Gelfand, MD, MSCE, of the University of Pennsylvania Perelman School of Medicine in Philadelphia, and colleagues. (medpagetoday.com)
  • In addition to age and IBD subtype, the severity of atopic dermatitis played a role in the increased risk of IBD. (medpagetoday.com)
  • The finding that this risk increases with worsening severity of AD suggests a possible causal association," Gelfand and colleagues concluded. (medpagetoday.com)
  • Women are particularly susceptible to osteoporosis in the jawbone and elsewhere, and the risk of osteoporosis increases with age. (livestrong.com)
  • An inactive lifestyle increases your risk of developing bone problems in your jaw and elsewhere in your body. (livestrong.com)
  • Quantitative risk assessment for food allergens has made considerable progress in recent years, yet acceptability of its outcomes remains stymied because of the limited extent to which it has been possible to incorporate severity as a variable. (ilsi.eu)
  • It may be necessary to generate new data (such as those from single dose-challenges) to reliably identify the effect of dose on severity for use in quantitative risk assessment. (ilsi.eu)
  • Hepatic decompensation and critical care needs increased among patients admitted with alcoholic hepatitis, including hepatic encephalopathy ( P = .037), gastrointestinal bleeding ( P = .01), a need for increased oxygen ( P = .024), vasopressor support ( P = .005), and initiation of hemodialysis ( P = .007). (medscape.com)
  • thus, we should have expected fewer severe and severe and critical COVID-19 among pregnant wom- critical COVID-19 patients in periods 2 and 3, but we en and all women of reproductive age hospitalized observed the opposite. (cdc.gov)
  • The ratio on COVID-19 severity among pregnant persons in- between pregnant women with critical COVID-19 fected with the Delta variant are consistent with and all women of reproductive age hospitalized for those of other studies ( 2 , 6-8 ). (cdc.gov)
  • Critical severity is coming to Acunetix Standard & Premium. (acunetix.com)
  • So, understanding the mechanisms driving daily variability in asthma severity could have significant implications for treatments. (powerofpositivity.com)
  • Conversely, when ACE2 expression is reduced, sodium and amino acid uptake are also reduced, thus increasing susceptibility to intestinal inflammation. (news-medical.net)
  • In pregnancy, there is an increased susceptibility and/or severity of several infectious diseases. (wikipedia.org)
  • Pregnancy may also increase susceptibility for toxoplasmosis. (wikipedia.org)
  • an increase in the magnitude and frequency of extreme events, such as droughts, will exacerbate the problem (Fedoroff et al. (springer.com)
  • Also, recurrences of herpes genitalis increase in frequency during pregnancy. (wikipedia.org)
  • The effect can be so dramatic that in some cases hunting can increase not only the proportion of infections and deaths, but also the absolute numbers. (webwire.com)
  • Various behavioral and environmental factors, such as exercise, air temperature, sleep environment, and body posture, have been known to affect asthma severity. (powerofpositivity.com)
  • The team then set out to determine how much the circadian rhythm dictates asthma severity compared to behavioral/environmental factors. (powerofpositivity.com)
  • The same level might be looked on more or less favorably depending on any improving or deteriorating trends in one or more factors. (fdic.gov)
  • The severity of reaction, particularly following accidental exposure, depends on multiple factors, related to the allergen, the host and any treatments which may have been administered. (ilsi.eu)
  • Among the 47 original research studies summarized here, chart reviews found that serum vitamin D levels predicted COVID-19 mortality rates (16 studies) and linearly predicted COVID-19 illness severity (8 studies). (frontiersin.org)
  • Influenza activity is increasing across the country and CDC has received reports of severe influenza illness. (cdc.gov)
  • The outlook depends on the severity of the illness. (medlineplus.gov)
  • Patients are in need of new treatments that can improve survival outcomes, and these positive results support the potential of KEYTRUDA in combination with chemotherapy as a first-line treatment for patients with the most common form of malignant mesothelioma. (merck.com)
  • Increase in number of reported COVID-19 deaths to 83 deaths (56 males, 28 females) between 11-17 April from 47 deaths between 4-10 April 2021 (Figure 7). (who.int)
  • We investigated both long-term and short-term air pollution exposure, which may influence COVID-19 severity through different mechanisms," said Zhanghua Chen, assistant professor at USC, and co-first author of the study. (eastmojo.com)
  • Gelfand and team used treatments as a proxy for atopic dermatitis severity, which they said "makes it difficult to separate the effects of treatment exposure from those of AD severity. (medpagetoday.com)
  • Conclusions: Coccidioidomycosis incidence rates have significantly increased during the last 5 years among military beneficiaries. (usuhs.edu)
  • Serum C3 and C4 concentrations were significantly increased in CU patients as compared with the healthy subjects and exceed the normal lab range by about 5% and 10%, respectively. (biomedcentral.com)
  • 4. Systolic, mean arterial and diastolic blood pressures decreased with increasing hepatic damage ( P = 0.031, P = 0.01 and P = 0.038 respectively). (portlandpress.com)
  • Damage quantification tools are used to analyse data to know the type, size and severity of damage. (thapar.edu)
  • An outbreak increases dramatically when hunting occurs between the birth season and the next mating season. (webwire.com)
  • Insufficient protective equipment and limited access to testing are dramatically increasing the severity of the crisis. (thenation.com)
  • But the new findings revealed a decrease, not an increase, in ACE2 in mice kidney membranes and no change in lung membranes. (scienceblog.com)
  • In view of this the number of recipients in the header of a give group MMS message thread on any of the devices should not increase or decrease if recipients reply to the MMS. (mozilla.org)
  • In all, 212 patients reported increased alcohol intake, 161 reported little change over the past year, and 253 said they were abstinent. (medscape.com)
  • Nitric oxide synthase activity increased with the degree of liver dysfunction ( P = 0.033) and was highest in patients with Child-Pugh score C. Systolic blood pressure correlated with nitric oxide synthase activity in patients with Child-Pugh score C ( P = 0.029). (portlandpress.com)
  • This lack of data exchange may leave some patients at a disadvantage and may increase care inequalities for patient populations that already experience disparities. (the-rheumatologist.org)
  • To assess the pattern of complement proteins C3 and C4 - the acute phase reactants in patients with CU. C3, C4 and CRP concentrations were measured in serum of 70 patients showing different degrees of urticarial severity as well as in 33 healthy subjects. (biomedcentral.com)
  • Serum complement C3 and C4 concentrations were measured in CU patients with different degrees of urticarial severity in comparison with healthy subjects and normal population reference ranges. (biomedcentral.com)
  • The actions aimed at reducing drought risks and impacts on farms can be categorised according to their timescale, whether they are aimed at increasing water supply or reducing demand, and their spatial scale of intervention (Iglesias et al. (springer.com)
  • While the recorded number of ransomware attacks has remained steady over the past three years, the severity of the attacks has increased. (scoop.co.nz)
  • Scientists previously believed that certain behaviors increased asthma attacks, like sleep, body posture, and physical activities. (powerofpositivity.com)
  • 6. The Framework proposes concrete actions which include, among others, enhancing epidemiological and laboratory surveillance, mapping cholera hotspots, improving access to timely treatment, strengthening partnerships and community engagement, increasing investments in clean water and sanitation for the most vulnerable communities, and promoting research. (who.int)
  • Study suggests high BMI may improve cancer survival. (asianage.com)
  • High-volume squats may increase testosterone levels. (livestrong.com)
  • Vitamin D deficiency also increases the activity of the X-chromosome-linked "Renin-Angiotensin" System, making vitamin D deficient individuals (especially men) more susceptible to COVID-19's deadly "cytokine storm" (dramatic immune system overreaction). (frontiersin.org)
  • These drugs, by different mechanisms, block the actions of a peptide that causes narrowing of blood vessels and fluid retention by the kidneys, which result in increased blood pressure. (scienceblog.com)
  • This report presents the use of improved b value analysis to differentiate Ib values for indication of failure mechanisms in ductile and brittle material. (thapar.edu)
  • Amplitude, absolute energy, improved b value, load and other parameters were plotted with time to understand failure mechanisms in ductile and brittle materials. (thapar.edu)
  • however, because of the lack of an advanced method to classify data regarding the injury severity in RTAs and the fragmentation of the original sources of these data, the road traffic safety authorities encounter difficulties in analyzing the epidemiology of injury patterns and mechanisms of RTAs as well as the effects on the victims, their families, and national resources. (tmu.edu.tw)
  • After reviewing the classification methods of RTA injury severity applied in developed countries, we analyzed the difficulties of injury prevention that are caused by a lack of effective classification of RTA injury severity in Taiwan. (tmu.edu.tw)
  • The reported classification of positive cases by severity reflects the status at first day of admission at the last day of the reporting week. (who.int)
  • This paper aims to understand how irrigated agriculture in a humid climate has been affected by past droughts and how different actors have adapted their activities and strategies over time to increase their resilience. (springer.com)
  • Electronic health records (EHRs) are designed to provide physicians with a complete picture of a patient's condition, improving care and decreasing costs for those with chronic illnesses, such as systemic lupus erythematosus (SLE). (the-rheumatologist.org)
  • Reduced ACE2 expression on intestinal epithelium weakens the mammalian target of the rapamycin (mTOR) pathway, thus altering anti-microbial peptides (AMPs) expression with increased autophagy. (news-medical.net)
  • Recently, it has been shown and validated that presence and severity of emphysema on computed tomography could be estimated by a novel spirometry based index, the emphysema severity index (ESI). (lu.se)
  • We sought to determine the effect of gender and estrogen status on the severity of choroidal neovascularization (CNV) in a mouse model for experimental choroidal neovascularization. (duke.edu)
  • 7 days, decreased current health status and increased severity. (cdc.gov)
  • Varicella occurs at an increased rate during pregnancy, but mortality is not higher than that among men and non-pregnant women. (wikipedia.org)
  • This may be due to a statistically significant increase in GI bleeds and renal dysfunction that we noted during the pandemic," said Jain. (medscape.com)
  • As the world's attention has been riveted upon the growing COVID-19 pandemic, many researchers have written brief reports supporting the hypothesis that vitamin D deficiency is related to the incidence and severity of COVID-19. (frontiersin.org)
  • As the worldwide case numbers increased, the WHO declared on March 11, 2020, that COVID-19 had reached the pandemic stage. (medscape.com)
  • This raises concern about the potential further increase of the cholera burden, including large-scale outbreaks in big cities. (who.int)
  • A new study found why asthma severity gets worse at night. (powerofpositivity.com)
  • The researchers found that both groups had their lowest lung function during the night at around 4 AM. They explained that the worsening asthma severity might typically go unnoticed during sleep. (powerofpositivity.com)
  • A study at the University of Kansas, Washington University, St. Louis, reported in the July 2010 issue of, 'Fiziol Cheloveka,' found that volunteers using a similar exercise protocol showed a significant increase in testosterone levels. (livestrong.com)
  • As more sites are evaluated, the sites at which fluorides, hydrogen fluoride, and fluorine is found may increase. (cdc.gov)
  • We then proposed a method for classifying injury severity and a potential model for the timely collection and integration of these data. (tmu.edu.tw)
  • The cytokine storm then induces systemic vasodilation and increases vascular permeability, thus leading to thrombotic complications, pulmonary edema, and multi-organ failure. (news-medical.net)
  • Postoperative complications were stratified by Cc grade severity: minor (I, II, and III) and severe (IV and V). Stepwise regression models generated dataset-specific predictive models for Cc groups. (ijssurgery.com)
  • FRIDAY, Feb. 2, 2024 (HealthDay News) -- Caffeine restriction can help improve and reduce the severity of primary monosymptomatic nocturnal enuresis (PMNE), according to a study recently published in BMJ Paediatrics Open . (msdmanuals.com)
  • A study published in the April 2005 issue of, 'Sports Medicine,' notes resistance exercises that work a large muscle mass with sufficient intensity, may increase testosterone levels. (livestrong.com)