• This RFA, Mechanisms of Genomic Instability from the Exposure of Mammalian Cells to High-LET Ionizing Radiations, is related to the priority areas of biomedical and environmental health research. (nih.gov)
  • Wang pointed out that many human malignancies have a p53 mutation and that other investigators have shown that the loss of p53 can result in genomic instability, increased chromosomal rearrangements, and mutation. (nih.gov)
  • Radiation induced cancer is triggered by chromosomal damage or genomic instability [ 3 ]. (biomedcentral.com)
  • Progression to BC is usually associated with acquisition of additional chromosomal aberrations beyond the underlying t(9;22) chromosomal translocation that characterizes CML.4 The primary abnormality in CML the oncogene may induce genomic instability that can predispose cells to additional mutations. (abt-888.net)
  • This can lead to fibrosis of the heart muscle and valvular tissues and vessels and cause a myriad of late effects including valvular stenoses or regurgitation, myopathies, a constrictive pericarditis, or conduction abnormalities, explained Torunn Yock, MD , director of pediatric radiation oncology and chair of quality assurance and improvement in the department of radiation oncology at Boston's Massachusetts General Hospital. (cancernetwork.com)
  • RIHD comprises a spectrum of heart disease including cardiomyopathy, pericarditis, coronary artery disease, valvular heart disease and conduction system abnormalities. (nih.gov)
  • Radiation therapy alone tends to increase the risk for coronary artery disease, valvular disease, pericarditis and similar issues that we don't see with anthracycline exposure alone,' said Dr. Mulrooney, who is also director of the Long-Term Follow-Up Clinic for childhood cancer survivors at the university. (cancernetwork.com)
  • Ionizing radiation also causes damage in a dose- and fractiondependent way but can result in narrowing and fibrosis of the arteries, which leads to earlier coronary artery disease. (cancernetwork.com)
  • Early recognition is important because drug-induced lung disease can often be reversed if appropriate therapy is instituted soon after the onset of symptoms. (medscape.com)
  • Although ultrasonography has no direct role in the management of drug-induced lung disease, it is useful in confirming pleural effusions and in assessing pleural intervention. (medscape.com)
  • Busulfan toxicity causes drug-induced pulmonary damage after prolonged exposure, usually after 3-4 years of therapy. (medscape.com)
  • The mechanisms of the drug-induced and radiation-induced pathogenesis differ somewhat, but the mechanisms have not yet been fully elucidated. (cancernetwork.com)
  • The study concludes that the RF-EMF may induce oxidative stress with an increased level of reactive oxygen species, which may lead to infertility. (biomedcentral.com)
  • Lipid peroxidation, a marker of oxidative stress, significantly increased with cadmium exposure but significantly decreased with spirulina supplementation in a dose-dependent manner. (naturalnews.com)
  • In line with the cadmium studies, a study published in the journal Food Chemical Toxicology in 2007 found that spirulina protects against oxidative stress induced by mercuric chloride. (naturalnews.com)
  • Signs and symptoms include psychomotor developmental abnormalities, speech delay, weakness and spasm of the extremities, dystonia, and metabolic acidosis. (nih.gov)
  • Conclusion: NOS1 -/- mice represent a model system for dissecting the developmental abnormalities leading to esophageal-mediated TBI-induced seizures. (wustl.edu)
  • Exposure to particulate matter (PM) has been associated with a range of health impacts, including neurological abnormalities that affect neurodevelopment, neuroplasticity, and behavior. (bvsalud.org)
  • About 30 percent of people with xeroderma pigmentosum develop progressive neurological abnormalities in addition to problems involving the skin and eyes. (medlineplus.gov)
  • All of the types increase the risk of skin cancer, although some are more likely than others to be associated with neurological abnormalities. (medlineplus.gov)
  • In addition to the hospital or clinic's specialized staff, physicians may access resources from or contact the following organizations for assistance in estimating fetal radiation dose. (cdc.gov)
  • The National Council on Radiation Protection and Measurements ' Report No. 174, "Preconception and Prenatal Radiation Exposure: Health Effects and Protective Guidance" [NCRP2013] provides detailed information for assessing fetal doses from internal uptakes. (cdc.gov)
  • The International Commission on Radiological Protection's "Publication 84: Pregnancy and Medical Radiation" [ICRP2000] provides fetal dose estimations from medical exposures to pregnant women. (cdc.gov)
  • Once the fetal radiation dose is estimated, potential health effects can be assessed. (cdc.gov)
  • Irradiation-induced lipid peroxidation in fetal brain cultures from NOS1 -/- or wild-type mice was reduced by MnSOD-PL. Right-sided vagotomy did not alter the TBI radiation response of wild-type or reverse the radiosensitivity of NOS1 -/- mice. (wustl.edu)
  • EMF Exposure on Fetal and Childhood Abnormalities: Systematic Review and Meta-Analysis," Open Medicine, May 12, 2023. (microwavenews.com)
  • Fetal and childhood abnormalities were more common in parents who have been exposed to EMFs compared to those who have not. (microwavenews.com)
  • Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. (bvsalud.org)
  • High morphological abnormality and mortality rates have been reported in the pale grass blue butterfly, Zizeeria maha , since the Fukushima nuclear accident. (nature.com)
  • 6 ADVERSE REACTIONS The most common adverse reactions in adults for the: prevention of chemotherapy-induced nausea and vomiting (greater than or equal to 5%) are: headache, malaise/fatigue, constipation, diarrhea. (drugcentral.org)
  • Prevention of Chemotherapy-Induced Nausea and Vomiting. (drugcentral.org)
  • monitor with electrocardiograms (ECGs) if concomitant electrolyte abnormalities, cardiac failure or arrhythmias, or use of other QT prolonging drugs. (nih.gov)
  • Radiation-induced vasculopathy - Radiation treatment for cancers of the head and neck may lead to delayed toxicity to the nervous system. (stroke.org)
  • [ 4 , 5 ] Visible AK lesions may be surrounded by tissue that clinically appears unaltered but bears significant ultraviolet-induced histological and genetic abnormalities. (medscape.com)
  • RESEARCH OBJECTIVES Background A striking phenotypic characteristic of high-LET-induced GI in primary human or rodent cells is the long-term accumulation of genetic abnormalities (e.g., chromosomal aberrations) among progeny of irradiated cells. (nih.gov)
  • The potential causes of POI include chromosomal abnormalities and genetic mutations, autoimmune factors, and some medical treatments, including surgery, chemotherapy, and radiation therapy. (umn.edu)
  • Migraine-related stroke - Migraine is associated with abnormalities of platelet, coagulation and blood vessel inner lining function. (stroke.org)
  • Aim: We sought to define the mechanism of total body irradiation (TBI)-induced seizures in NOS1 -/- mice and amelioration by intra-esophageal manganese superoxide dismutase-plasmid liposomes (MnSOD-PL). Materials and Methods: We evaluated the role of vagus nerve pathways in irradiation-induced seizures using biochemical, physiologic, and histopathologic techniques. (wustl.edu)
  • At the biochemical level, stress responses might have been induced in cattle in the contaminated areas 33 . (nature.com)
  • Increased production of urate may be caused by increased nucleoprotein turnover in hematologic conditions (eg, lymphoma, leukemia, hemolytic anemia) and in conditions with increased rates of cellular proliferation and cell death (eg, psoriasis, cytotoxic cancer therapy, radiation therapy). (msdmanuals.com)
  • This is a very serious problem, and it is primarily due to radiation therapy of young people with hematologic cancers, like Hodgkin's lymphoma. (cancernetwork.com)
  • C2950 Chromosome Abnormality C99147 Neonatal Research Network Terminology C98683 3-Methylglutaconic Aciduria Type 1 3-Methylglutaconic Aciduria Type 1 3-methylglutaconic aciduria inherited in an autosomal recessive pattern and caused by mutations in the AUH gene. (nih.gov)
  • Among the best characterized of these abnormalities are the increased expression of mutations in the tumor-suppressor gene TP53, which encodes tumor protein p53. (studylibid.com)
  • CML cells may also have altered DNA repair processes including error-prone HR and NHEJ mechanisms.16-19 However the relationship of these abnormalities to chromosomal instability in CML cells is less well studied. (abt-888.net)
  • We studied mechanisms of chromosomal instability in CML CD34+ cells after radiation-induced DNA damage including induction of repeated cycle of chromosomal breakage-fusion-bridge (BFB) formation and the role of NHEJ repair in this process. (abt-888.net)
  • RT improves survival in many cancers, but it involves some inevitable complications. (nih.gov)
  • Xeroderma pigmentosum is associated with an increased risk of UVR-induced cancers. (medlineplus.gov)
  • These second cancers are more common in patients who have received radiotherapy for their retinoblastoma, and even more so when this radiation has been given before 12 months of age. (medindia.net)
  • 1992. Radiation dose assessment from ingestion pathway in Saudi Arabia. (cdc.gov)
  • Although radiation doses to a fetus tend to be lower than the dose to the mother, due to protection from the uterus and surrounding tissues, the human embryo and fetus are sensitive to ionizing radiation at doses greater than 0.1 gray (Gy). (cdc.gov)
  • Health effects to a fetus from radiation exposure depend largely on the radiation dose. (cdc.gov)
  • Dose from an external source of radiation to the mother's abdomen. (cdc.gov)
  • Hospital medical physicists and health physicists are good resources for expertise in estimating the radiation dose to the fetus. (cdc.gov)
  • The purpose of this study was to establish the dose-response curves for biological dosimetry of the Dong Nam Institute of Radiological and Medical Sciences to monitor radiation exposure of local residents in the vicinity of the nuclear power plant. (bvsalud.org)
  • We also present the results that the dose-response curve for dicentric chromosomes plus fragments could be more effective for dose estimation following low-dose radiation accidents. (bvsalud.org)
  • The primary purpose and interest of both agencies in this Request for Applications (RFA) is to define and understand GI from chronic low-dose exposure of mammalian cells to high energy nuclei of high atomic number (referred to as HZE) particles (e.g., iron) and to high-energy protons, which are likely to be major sources of human exposure to high-LET radiation during extended space flight. (nih.gov)
  • Current radiation protection standards assume that any dose of radiation, no matter how small, involves a risk to human health. (world-nuclear.org)
  • If the dose is too high for repairs to be made satisfactorily, there is a potential increase in the risk of getting cancer later in life. (world-nuclear.org)
  • The overall goal and purpose of radiation safety and dose management is to conduct individual radiation risk assessment for each patient, providing the patient involved with an opportunity to give informed consent relating to their radiation risk. (netce.com)
  • Studies indicate that improved clinician education can help to limit radiation dose and associated complications. (netce.com)
  • When granisetron hydrochloride tablets were administered with food, AUC was decreased by 5% and C max increased by 30% in non-fasted healthy volunteers who received a single dose of 10 mg. (nih.gov)
  • The increases were transient and did not appear to be related to dose or duration of therapy. (drugcentral.org)
  • Invasive electrophysiological studies are usually important for determining the mechanisms of induced arrhythmias and providing guidance for ablation. (alliedacademies.org)
  • The lowered radiation and temperatures of the subtropical winter season induce a physiological dwarfism in sugarcane (Saccharum spp. (researchandmarkets.com)
  • An increased understanding of the molecular mechanisms controlling these events would increase our ability to combat selective cytopenias and could facilitate hematopoietic reconstitution following radiation, chemotherapy, and marrow or primary sclerosing cholangitis (PSC) transplantation. (nih.gov)
  • The cyclin-dependent kinase inhibitor p21 is induced by both p53-dependent and -independent mechanisms following stress, and induction of p21 may cause cell cycle arrest. (aacrjournals.org)
  • Radiation-induced heart disease (RIHD) is one of the most serious complications. (nih.gov)
  • With inflammation & injury to the gut lininng, mucosal absorption of normally-excluded substances increases dramatically. (jillcarnahan.com)
  • During chemotherapy that induces vomiting, mucosal enterochromaffin cells release serotonin, which stimulates 5-HT 3 receptors. (nih.gov)
  • Lack of response to empiric antibiotic treatment and an imaging pattern of organizing pneumonia should raise suspicion of everolimus-induced pneumonitis in patients undergoing therapy with this drug. (medscape.com)
  • Increasing age, conjoint radiation therapy, and high concentrations of oxygen are associated with high rates of lung toxicity. (medscape.com)
  • With the increasing incidence of thoracic tumors, radiation therapy (RT) has become an important component of comprehensive treatment. (nih.gov)
  • The side effects of Radiation Therapy can be classified as Acute, Subacute and Delayed. (cancer.org)
  • My wife received postoperative whole brain radiation therapy for a single brain metastasis in the Summer of 1998. (cancer.org)
  • The Pet Scan showed globally decreased radiotracer uptake within the brain, bilaterally, consistent with involutional change and prior radiation therapy. (cancer.org)
  • Particle therapy (PT) that utilizes protons and carbon ions offers a promising way to reduce the side effects of radiation oncology, especially in pediatric patients. (mdpi.com)
  • Radiation therapy can buy years or decades of life for children with various forms of cancer. (cancernetwork.com)
  • That risk can be compounded by radiation therapy. (cancernetwork.com)
  • Gonadotropin therapy or the use of pulsatile gonadotropin-releasing hormone (GnRH) therapy may be required to induce ovulation in patients with infertility whose underlying pathology cannot be reversed. (medscape.com)
  • Treatments like chemotherapy and radiation therapy can induce menopause with all the associated symptoms. (avihomeopathy.com)
  • The present results indicated that long-term microwave radiation can retard AD development and exert a beneficial effect against AD, suggesting that 900 MHz microwave exposure may be a potential therapy for AD. (microwavenews.com)
  • NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
  • The effects of IR on reproduction are of growing concern as the number of people exposed to radiation via medical procedures and environmental exposures is significantly increasing. (biomedcentral.com)
  • We conclude that consistent with advice in pediatric radiology, an approach that recommends that microwave radiation exposures be As Low As Reasonably Achievable (ALARA) seems sensible and prudent. (microwavenews.com)
  • It precedes both behavioral abnormalities and structural changes at the neuromuscular junction (NMJ) of mortalin -knockdown larvae that exhibit increased mitochondrial fragmentation. (plos.org)
  • Prenatal WiFi exposure increased the body weight, improved the spatial memory, and learning function and induced behavioral hyperactivity of male rats. (microwavenews.com)
  • Our goal is to restore ovarian function and improve quality of life in young cancer survivors. (umn.edu)
  • Additionally, affected individuals who smoke cigarettes have a significantly increased risk of lung cancer . (medlineplus.gov)
  • In addition to an increased risk of cancer on the surface of the eye, xeroderma pigmentosum is associated with noncancerous growths on the eye. (medlineplus.gov)
  • Heavy radiation is given to the chest area, and 10 to 20 years later the patients develop all kinds of very serious cardiac problems and associated difficulties, any one of which can cause death,' said Barrie R. Cassileth, PhD , who holds the Laurance S. Rockefeller Chair in Integrative Medicine and is chief of the integrative medicine service at Memorial Sloan-Kettering Cancer Center in New York City. (cancernetwork.com)
  • Many young cancer patients get a double whammy to the heart, receiving a combination of radiation to the chest and chemotherapy with anthracyclines, which are associated with cardotoxicities at higher lifetime cumulative doses, noted Daniel Mulrooney, MD , an assistant professor in the division of pediatric hematology/oncology/blood and marrow transplantation in the pediatrics department at the University of Minnesota in Minneapolis. (cancernetwork.com)
  • A new screening test for oesophageal (food pipe) cancer could dramatically improve survival from the disease, according to research published in the British Journal of Cancer this week. (news-medical.net)
  • Targeting a gene that protects cancer cells from the lethal effects of radiotherapy could help improve the impact of treatment, a leading Cancer Research UK scientist will tell conference delegates in Glasgow this week. (news-medical.net)
  • Over one hundred forms of cancer exist, and though induced by diverse factors, all result in changes to the DNA. (weizmann.ac.il)
  • These include boosting the production of infection-fighting white blood cells in cancer patients undergoing chemotherapy or radiation, and improving the success of bone marrow and peripheral blood cell transplants. (weizmann.ac.il)
  • 34 Recent evidence also suggests that the genomic abnormalities seen in cancer cells arise as downstream secondary effects of disturbed energy metabolism and are unlikely to provide useful information for therapeutic treatment strategies for the majority of GBM patients. (touchoncology.com)
  • This evokes vagal afferent discharge, inducing vomiting. (nih.gov)
  • Most of the ways a pregnant woman may be exposed to radiation, such as from a diagnostic medical exam or an occupational exposure within regulatory limits, are not likely to cause health effects for a fetus. (cdc.gov)
  • Potential imaging modalities are limited during pregnancy due to the desire to limit ionizing radiation exposure to the fetus. (springer.com)
  • We are surrounded by several types of ionizing and non-ionizing radiations and both have recognized causative effects on spermatogenesis. (biomedcentral.com)
  • Since it is impossible to cover all types of radiation sources and their biological effects under a single title, this review is focusing on radiation deriving from cell phones, laptops, Wi-Fi and microwave ovens, as these are the most common sources of non-ionizing radiations, which may contribute to the cause of infertility by exploring the effect of exposure to radiofrequency radiations on the male fertility pattern. (biomedcentral.com)
  • Radiation can be characterized into ionizing and non-ionizing radiations, of which the latter is differentiated in two forms: 1) extremely low frequency (ELF) or power line (60 Hz) electromagnetic fields (EMFs), and 2) radio frequency (RF) EMFs - which are produced by wireless radio waves/microwaves products. (biomedcentral.com)
  • Ionizing radiation is much more dangerous than non-ionizing radiations. (biomedcentral.com)
  • We know more about the sources and effects of exposure to [ionizing] radiation than to almost any other hazardous agent, and the scientific community is constantly updating and analysing its knowledge. (world-nuclear.org)
  • Radiation particularly associated with nuclear medicine and the use of nuclear energy, along with X-rays, is 'ionizing' radiation, which means that the radiation has sufficient energy to interact with matter, especially the human body, and produce ions, i.e. it can eject an electron from an atom. (world-nuclear.org)
  • This interaction between ionizing radiation and living tissue can cause damage. (world-nuclear.org)
  • The level of localized DNA damage caused by Ionizing radiation (IR) is believed to increase with elevating LET values of radiation. (studylibid.com)
  • Deutsch et al reported that BCR-ABL expression resulted in reduced expression of DNA repair proteins DNA repair deficiency and increased sensitivity to ionizing radiation.20 On the other hand Dierov et al21 and Koptyra et al22 showed that BCR/ABL expression promoted DNA DSBs and acquisition of chromosomal aberrations. (abt-888.net)
  • In this study we investigated whether CML CD34+ cells demonstrate enhanced susceptibility to chromosomal aberrations after exposure to ionizing radiation compared with cells from healthy persons. (abt-888.net)
  • THz radiation can affect biological activity in living cells, although it is non-ionizing radiation that does not damage DNA sequences. (microwavenews.com)
  • prevention of radiation-induced nausea and vomiting (≥ 2%) are: headache, constipation, and diarrhea. (nih.gov)
  • Contrary to public perception, nuclear power accidents have caused very few fatalities and the use of nuclear energy does not expose members of the public to significant radiation levels. (world-nuclear.org)
  • After irradiation, histological staining, immunohistochemical staining, and gene expression analysis were conducted following 1 or 14 days of in vitro culture (DIV). Our data indicated a significant loss of proliferating chondrocytes at 1 DIV, which was followed by regeneration attempts through chondrocytic cluster formation at 14 DIV. Accelerated levels of mineralization were observed, which correlated with increased proteoglycan production and secretion into the pericellular matrix. (mdpi.com)
  • For a trauma-induced dislocation, there is significant delay in cerebral edema in nephrotic syndrome. (missouripodiatric.com)
  • DNA damage response signaling pathways mediate cell cycle arrest and provide an opportunity for repair before replication or mitosis occurs.12 Typically cells with unstable chromosomal lesions are prevented from going through cell cycle by checkpoint control pathways.13-15 Therefore development of persistent chromosomal abnormalities involves several factors including acquisition of DSB misrepair of damage abnormal checkpoint responses and clonal growth advantage of resulting lesions. (abt-888.net)
  • The socio-economic and psychological impacts of radiation fears in the aftermath of nuclear accidents have caused considerable harm amongst exposed and non-exposed populations. (world-nuclear.org)
  • Radiation induced changes in cell division and increased chromosomal abnormalities were attributed to cellular response to resonance. (cdc.gov)
  • High-LET radiation enhanced cell death (Radiasi High LET meningkatkan kematian sel) Sarianoferni *, Endah Wahjuningsih** * Radiology Department Faculty of Dentistry Hang Tuah University ** Oral Biology Department Faculty of Dentistry Hang Tuah University Abstract High LET radiation is a selective radiotherapy, being effective for the treatment of advanced malignancies in head and neck regions. (studylibid.com)
  • Focusing on blood stem cells, a small group of bone marrow cells that produce some 200 billion new blood cells every day, Sachs ended up designing the first cell culture system able to grow, clone, and induce the development of different types of normal blood cells. (weizmann.ac.il)
  • In glioma ( 28 ) and in vascular smooth muscle cells ( 29 ), p21 facilitates active cyclin-Cdk complex formation and induces cell proliferation. (aacrjournals.org)
  • This approach, using retinoic acid combined with chemotherapy, is now standard procedure in treating human promyelocytic leukemia, and it has greatly increased survival rates. (weizmann.ac.il)
  • They results from an increase in cerebral edema(abnormal accumulation of fluid). (cancer.org)
  • Delayed radiation injuries result in increased tissue pressure from edema, vascular injury leading to infarction, damage to endothelial cells and fibrinoid necrosis of small arteries and arterioles(my wife suffered a stroke to the left basal ganlia area of the brain in January 2000, confirmed by an enhanced MRI). (cancer.org)
  • Radiation doses to the heart of about 5 Gy or greater in childhood are associated with long-term cardiovascular consequences, including early mortality. (cancernetwork.com)
  • The researchers found that spirulina doses of 125, 250 and 500 mg/kg significantly decreased the rates of cadmium-induced exencephaly, micrognathia and skeletal abnormalities. (naturalnews.com)
  • The higher doses it increases intra- cellular to extracellular potassium concentration is in the elderly. (missouripodiatric.com)
  • Patients must be off immunosuppressive doses of systemic steroids (≥ 10 mg/day prednisone or equivalent) for at least 14 days prior to study drug administration, and must have returned to neurologic baseline status postoperatively - The 4-week period of stability is measured after the completion of the neurologic interventions (ie, surgery and/or radiation). (mycancergenome.org)
  • Increased urate production may also occur as a primary hereditary abnormality and in obesity, because urate production correlates with body surface area. (msdmanuals.com)
  • Obesity - Studies suggest that obesity may increase risk. (cancerquest.org)
  • [ 3 ] However, if multiple AKs are present and if they are accompanied by signs of chronic actinic damage, the risk of malignant progression increases rapidly. (medscape.com)
  • This increased immunity helps to fight against the present disease whether that is acute, autoimmune, congenital or chronic disease. (avihomeopathy.com)
  • Prokinetics are the drugs which stimulate the movement of the gastrointestinal tract by increasing the frequency or strength of contractions and help move the contents in the upper GI tract still forwards. (mutalikpharmacology.com)
  • The clinical picture varies, depending upon the combination of abnormalities. (nih.gov)
  • While these procedures have clinical benefits, they are not without risks, particularly related to radiation exposure. (netce.com)
  • During the menopause FSH level increases and oestrogen level falls. (avihomeopathy.com)
  • An increase in chromosomal abnormalities may be a result of exposure to radiation, which was first reported by Martin et al. (biomedcentral.com)
  • But disease control or cure often comes at a very high price, in the form of late-term cardiotoxicities and significantly increased risk for early death. (cancernetwork.com)
  • Many prescription medications and dietary supplements can interact with levothyroxine and either increase or decrease its potency. (limamemorial.org)
  • Because of this patients symptoms and limit the quantity of solute from a radiation-induced decrease in the first year of life. (missouripodiatric.com)
  • Symptoms include anorexia(loss of apetite), sleepiness, lethargy(drowsiness) and an increase in neurological deficits. (cancer.org)
  • We employed LA-QPCR to test the hypotheses that PLRRP water and sediments would cause nuclear and mitochondrial DNA damage with and without full-spectrum, natural solar radiation. (nih.gov)
  • Fluoranthene with and without natural sunlight was a positive control for phototoxic polycyclic aromatic hydrocarbon-induced DNA damage. (nih.gov)
  • PLRRP samples caused DNA damage to both genomes, and this was not increased by sunlight exposure, suggesting the DNA damage was unlikely the result of PAH phototoxicity. (nih.gov)
  • Anthracyline exposure induces direct oxidative damage in muscle cells, which can over time lead to congestive heart failure. (cancernetwork.com)
  • are at increased risk of gout. (msdmanuals.com)
  • Those at increased risk for long-term radiation effects are children less than 2 and adults over 50 years of age. (cancer.org)
  • Reduction in ovarian function is known to increase the risk of cardiovascular disorders, osteoporosis, cognitive decline, and mood disorders, resulting in a reduced quality of life. (umn.edu)
  • There are several risk factors that can increase the chances of a spontaneous abortion. (home-remedies-for-you.com)
  • If concomitant use of ondansetron with other serotonergic drugs is clinically warranted, patients should be made aware of a potential increased risk for serotonin syndrome. (nih.gov)
  • A risk factor is something that increases your chances of getting a disease or condition. (newscholarshub.com)
  • A sedentary lifestyle increases risk of back pain compared to patients who engage in a more active lifestyle. (springer.com)
  • Increased body mass index (BMI) may be a risk factor but study results are conflicting. (springer.com)
  • It may be completely benign, or it may be an increased risk of sudden cardiac death. (alliedacademies.org)
  • Ventricular tachycardia occurring within the first 48 hours after admission is associated with an increased risk of death compared with ventricular tachycardia occurring within the first 48 hours after admission [ 2 ]. (alliedacademies.org)
  • This type of vasospasm increases the risk of an ischemic stroke. (stroke.org)
  • Migraine with aura is associated with an increased risk for ischemic and hemorrhagic stroke in women, especially those under age 55. (stroke.org)
  • Family history - Prior family history of myeloma increases risk of MM development. (cancerquest.org)
  • He showed that the proteins he had identified, and some other compounds, set leukemic cells back on the right track -- inducing them to differentiate into normal-behaving mature cells. (weizmann.ac.il)
  • The biological effects of microwave radiations effectively begin with the development of radar early during World War II. (biomedcentral.com)
  • Adverse biological effects of naturally high background radiation have been documented 5 , but presently, radiation-based technologies are widespread in society, which leads to the relatively high possibility of radiation exposure, whether intentional or accidental, for anyone. (nature.com)
  • During recent years, an increasing percentage of male infertility has to be attributed to an array of environmental, health and lifestyle factors. (biomedcentral.com)
  • Male infertility is likely to be affected by the intense exposure to heat and extreme exposure to pesticides, radiations, radioactivity and other hazardous substances. (biomedcentral.com)
  • The results of chromosomal aberrations followed the Poisson distribution in all individual and averaged data which include inter-individual variation in radiation susceptibility. (bvsalud.org)
  • Less common modes of presentation include blood in the anterior chamber (seen behind the cornea), cataract, increased pressure in the eye and inflammation of the tissues surrounding the eye. (medindia.net)