• We established a scalable source of human spinal cord NSCs that includes all spinal cord neuronal progenitor cell types," said Kumamaru. (disabled-world.com)
  • This work not only defines the role of the ARTS gene in the underlying mechanism of mammalian tumor cell resistance to programmed cell death, but also links this gene to another hallmark of cancer, stem and progenitor cell proliferation," said Marion Zatz, who oversees cell death grants, including Steller's, at the NIH's National Institute of General Medical Sciences. (scienceblog.com)
  • Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from adult cells. (evotec.com)
  • The iPSC technology was pioneered by Shinya Yamanaka's lab in Kyoto, Japan, who showed in 2006 that the introduction of four specific genes encoding transcription factors could convert adult cells into pluripotent stem cells. (evotec.com)
  • Pluripotent stem cells hold great promise in the field of regenerative medicine. (evotec.com)
  • Here, we describe human conjunctival development in a self-formed ectodermal autonomous multi-zone (SEAM) of cells that were derived from human-induced pluripotent stem cells (hiPSCs) and mimic whole-eye development. (listlabs.com)
  • Derived from human pluripotent stem cells, these diverse cells advance disease modeling and may provide new, scalable source of replacement cells for spinal cord injuries (SCI). (disabled-world.com)
  • Researchers at University of California San Diego School of Medicine report that they have successfully created spinal cord neural stem cells (NSCs) from human pluripotent stem cells (hPSCs) that differentiate into a diverse population of cells capable of dispersing throughout the spinal cord and can be maintained for long periods of time. (disabled-world.com)
  • We further demonstrated that suppression of autophagy using either pharmacological inhibitors or RNA interference of essential autophagy genes enhanced cell death induced by IM in cell lines and primary CML cells. (lu.se)
  • Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
  • Evolutionary analysis of Burkholderia pseudomallei identifies putative novel virulence genes, including a microbial regulator of host cell autophagy. (bvsalud.org)
  • Here we show that several previously uncharacterized B. pseudomallei genes bearing genetic signatures of rapid adaptation (positive selection) can induce diverse cellular phenotypes when expressed in mammalian cells . (bvsalud.org)
  • Recently, shared mutations between clonal B cells in MBL/CLL and CD34+ hematopoietic progenitor cells (HPC) have been identified. (confex.com)
  • In mature B and T cells, she could not find any, however, so she began to look at cells earlier and earlier in development, until finally she was comparing hematopoietic progenitor and stem cells. (scienceblog.com)
  • The increase in the number of hematopoietic progenitor and stem cells in Sept4-deficient mice brings with it the possibility of accelerating the accumulation of mutations in stem cells," says Garcia-Fernandez. (scienceblog.com)
  • Elimination of BCR/ABL-dependent intracellular signals triggers apoptosis, but it is unclear whether this activates additional cell survival and/or death pathways. (lu.se)
  • Research associate Maria Garcia-Fernandez, Hermann Steller, head of the Strang Laboratory of Apoptosis and Cancer Biology, and their colleagues explored the activity of a gene called Sept4, which encodes a protein, ARTS, that increases programmed cell death, or apoptosis, by antagonizing other proteins that prevent cell death. (scienceblog.com)
  • They have more stem cells with enhanced resistance to apoptosis. (scienceblog.com)
  • We make a connection between apoptosis, stem cells and cancer that has not been made in this way before: this pathway is critically important in stem cell death and in reducing tumor risk," Steller says. (scienceblog.com)
  • The work supports the idea that the stem cell is the seed of the tumor and that the transition from a normal stem cell to a cancer stem cell involves increased resistance to apoptosis. (scienceblog.com)
  • ARTS interferes with molecules called inhibitor of apoptosis proteins (IAPs), which prevent cells from killing themselves. (scienceblog.com)
  • By inhibiting these inhibitors, under the right circumstances ARTS helps to take the brakes off the process of apoptosis, permitting the cell to die on schedule. (scienceblog.com)
  • Notably, several of these phenotypes are plausibly related to virulence , including multinuclear giant cell formation, apoptosis , and autophagy induction. (bvsalud.org)
  • Aim: To investigate the impact of tumor-cell expression of thyroid transcription factor 1 (TTF1) on outcomes after irradiation of limited-disease small cell lung cancer (LD-SCLC). (iiarjournals.org)
  • The present study was performed to investigate the effect of TTF1 expression in tumor cells on locoregional recurrence-free survival (LRFS), metastasis-free survival (MFS), and overall survival (OS) in patients irradiated for limited disease SCLC (LD-SCLC). (iiarjournals.org)
  • Particularly in patients presenting with adenocarcinoma, tumor-cell expression of TTF1 was associated with improved overall survival ( 6 ). (iiarjournals.org)
  • We have shown here that IM induces autophagy in CML blast crisis cell lines, CML primary cells, and p210BCR/ABL-expressing myeloid precursor cells. (lu.se)
  • By identifying a mechanism that regulates programmed cell death in precursor cells for blood, or hematopoietic stem cells, the work is the first to connect the death of such cells to a later susceptibility to tumors in mice. (scienceblog.com)
  • Similarly, a HPC origin of BRAF V600E mutations in hairy cell leukemia (HCL) has been uncovered, strengthening the notion that at least a fraction of somatic mutations may occur in CD34+ HPC before the malignant transformation of some B cell neoplasms. (confex.com)
  • Importantly, clonal mutations in WM B cells were undetectable in normal cells. (confex.com)
  • Thus, the few WM subclonal mutations observed in patients' lymphopoiesis could not result from contamination during FACSorting since in such cases, WM clonal mutations would become detectable in normal cells. (confex.com)
  • Newborn ARTS-deprived mice had about twice as many hematopoietic stem cells as their normal, ARTS-endowed peers, and those stem cells were extraordinary in their ability to survive experimentally induced mutations. (scienceblog.com)
  • In the end, that leads to more cells accumulating mutations that cannot be eliminated. (scienceblog.com)
  • We used FACSorting to isolate 57 cell subsets from bone marrow (BM) aspirates of 10 WM patients: CD34+ HPC, B cell precursors, residual normal B cells (if detectable), WM B cells, plasma cells (PCs) and T cells (germline control). (confex.com)
  • A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy. (genomeweb.com)
  • Apple is investigating hydrogen fuel cells in mobile devices as an alternative to present battery charging technology, partly to achieve far longer battery life, but also to be more ecologically sound. (appleinsider.com)
  • As a consequence of this increased consumer awareness, electronics manufacturers have become very interested in developing renewable energy sources for their products, and they have been exploring a number of promising renewable energy sources such as hydrogen fuel cells. (appleinsider.com)
  • Apple doesn't exactly say that hydrogen fuel cells are the perfect battery for the future, but it does list exactly why it calls the technology so "promising. (appleinsider.com)
  • Hydrogen fuel cells have a number of advantages," says Apple. (appleinsider.com)
  • For instance, one example proposes that "the fuel cells may be proton exchange membrane (PEM) fuel cells that use hydrogen as a fuel. (appleinsider.com)
  • Define the cellular origin of WM by comparing the genetic landscape of WM cells to that of CD34+ HPC, B cell precursors and residual normal B cells. (confex.com)
  • In parallel, MYD88 p.L252P (orthologous position of the human L265P mutation) transgenic mice were crossed with conditional Sca1 Cre , Mb1 Cre , and Cγ1 Cre mice to selectively induce in vivo expression of MYD88 mutation in CD34+ HPC, B cell precursors and germinal center B cells, respectively. (confex.com)
  • Notably, we found MYD88 L265P in B cell precursors from 1/10 cases and in residual normal B cells from 4/10 patients, which were confirmed by ASO-PCR and ddPCR. (confex.com)
  • Indeed, these more sensitive methods detected MYD88 L265P in B cell precursors from 6/10 cases and in residual normal B cells from 6/10 patients. (confex.com)
  • CXCR4 was simultaneously mutated in B cell precursors and WM B cells from one patient. (confex.com)
  • Stem cells, the prodigious precursors of all the tissues in our body, can make almost anything, given the right circumstances. (scienceblog.com)
  • To extend the time between charges, Nathan's group built a prototype device that converts ambient light into electricity using an array of solar cells made of thin-film hydrogenated amorphous silicon that's designed to sit within the phone's screen. (ieee.org)
  • Swiss-based PV manufacturing equipment specialist INDEOtec SA has successfully gained tool acceptance for its PECVD process tools from both Fraunhofer ISE and the King Abdullah University of Science and Technology (KAUST) in Saudi Arabia for next-generation heterojunction solar cells. (pv-tech.org)
  • We believe in upgraded metallurgical silicon as an important resource for the production of solar cells in the mid- to long-term perspective" said Anton Milner, CEO of Q-Cells. (pv-tech.org)
  • Treatment of dental complications in sickle cell disease. (jefferson.edu)
  • Mulimani P, Ballas SK, Abas AB, Karanth L. Treatment of dental complications in sickle cell disease. (jefferson.edu)
  • BACKGROUND: Sickle cell disease is the most common single gene disorder and the commonest haemoglobinopathy found with high prevalence in many populations across the world. (jefferson.edu)
  • Management of dental complications in people with sickle cell disease requires special consideration for three main reasons. (jefferson.edu)
  • Hence this review was undertaken to provide a basis for clinical care by investigating and analysing the existing evidence in the literature for the treatment of dental complications in people with sickle cell disease. (jefferson.edu)
  • OBJECTIVES: To assess methods of treating dental complications in people with sickle cell disease. (jefferson.edu)
  • SELECTION CRITERIA: We searched for published or unpublished randomised controlled studies of treatments for dental complications in people with sickle cell disease. (jefferson.edu)
  • AUTHORS' CONCLUSIONS: This Cochrane Review did not identify any randomised controlled studies assessing interventions for the treatment of dental complications in people with sickle cell disease. (jefferson.edu)
  • There is an important need for randomised controlled studies in this area, so as to identify the most effective and safe method for treating dental complications in people with sickle cell disease. (jefferson.edu)
  • and Karanth, Laxminarayan, "Treatment of dental complications in sickle cell disease. (jefferson.edu)
  • Health care services for severe NCDs such as type 1 diabetes, advanced rheumatic heart disease, and sickle cell disease, are usually provided at tertiary facilities in most countries. (who.int)
  • Background/aim: Large-cell neuroendocrine carcinoma (LCNEC) of the lung is a relatively uncommon and aggressive subset of pulmonary neuroendocrine tumors, which include typical and atypical carcinoid, and small-cell lung cancer. (tubitak.gov.tr)
  • range 48 to 77 years) who underwent pulmonary resection for large-cell neuroendocrine carcinoma between January 2004 and December 2014 were investigated retrospectively. (tubitak.gov.tr)
  • SCLC develops in neuroendocrine cells. (healthline.com)
  • Desired cells are simply collected into a new tube and can immediately be used in downstream applications such as nucleic acid extraction, flow cytometry or culture. (stemcell.com)
  • The fluorochrome-labeled cells are analyzed by flow cytometry, which categorizes individual cells according to size, granularity, fluorochrome, and fluorochrome intensity. (cdc.gov)
  • Critically, a comprehensive assessment across specific cell types in the brain affected by severe COVID-19 is missing. (nature.com)
  • Small cell lung cancer (SCLC) represents 10% to 25% of all lung cancer and is characterized by rapid growth, early locoregional recurrence and early distant metastases ( 1 - 3 ). (iiarjournals.org)
  • Recent studies investigated the prognostic value of thyroid transcription factor 1 (TTF1) expression in non-small cell lung cancer (NSCLC) ( 4 - 7 ). (iiarjournals.org)
  • Small cell lung cancer (SCLC) makes up about 15% of lung cancers in the United States. (healthline.com)
  • It is also one of the two main divisions of lung cancer along with non-small cell lung cancer. (healthline.com)
  • This cell isolation kit targets non-B cells for removal based on specific surface antigens. (stemcell.com)
  • Sixty percent of cases express 1 or more T-cell antigens (CD3 + , CD43, or CD45RO). (medscape.com)
  • Specifically, we show that BPSS0180, a type VI cluster-associated gene , is capable of inducing autophagy in both phagocytic and nonphagocytic mammalian cells . (bvsalud.org)
  • Using a workflow combining laser microdissection and single-cell mass spectrometry, the researchers identified more than 1,700 proteins per liver cell. (genomeweb.com)
  • Unlike other forms of NCL that result in the accumulation of proteins and other substances in cells, contributing to cell death, the less-severe form of CLN8 disease is associated with very little buildup in cells. (medlineplus.gov)
  • At Memorial Sloan Kettering Cancer Center, our Merkcel cell carcinoma and skin cancer team include specialists in surgery, head and neck cancers, radiation oncology, medical oncology, and dermatology. (mskcc.org)
  • Each team member has expertise in evaluating and treating patients with cancers of the skin - including rare skin cancers like Merkel cell carcinoma. (mskcc.org)
  • Surgical management of large-cell neuroendocrinelung carcinoma: an ana" by FUNDA İNCEKARA, KORAY AYDOĞDU et al. (tubitak.gov.tr)
  • A new study by MSK scientists sheds light on how cancer cells hide out and remain undetected by our immune system, opening up a promising new avenue for treatment. (mskcc.org)
  • Accordingly, the clonotypic BCR detected in WM cells was unbiasedly investigated in all B cell maturation stages defined according to their molecular phenotype. (confex.com)
  • Keratinocyte growth factor (KGF), moreover, is necessary for the maturation of hiPSC-derived conjunctival epithelium-particularly the goblet cells-indicating key complementary roles of EGF and KGF in directing the differentiation and maturation, respectively, of the human conjunctival epithelium. (listlabs.com)
  • Anaplastic large cell lymphomas (ALCLs) are distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen (an activation marker for B or T cells). (medscape.com)
  • ALCL was recognized in 1985, when tumor cells consistently demonstrated labeling by the monoclonal antibody Ki-1, a marker later shown to recognize the CD30 antigen. (medscape.com)
  • Parents of a child with a family history of que tienen el gene del antígeno de superficie del virus de la Hepatitis B. El antígeno de superficie de la Hepatitis B (HBsAg) expresado en las genetically engineered Hansenula polymorpha yeast cells having the surface antigen gene of the Hepatitis B virus. (who.int)
  • Tiomersal es agregado como surface antigen (HBsAg) expressed in the cells of Hansenula polymorpha is purified through several chemical steps using recombinant regarding appropriate medical care in the unlikely event of a seizure. (who.int)
  • 100% (median of 79%, range: 55%-100%), suggesting that not all WM B cells differentiate into PCs. (confex.com)
  • This is in part because the high-quality, fresh-frozen human brain tissue from patients with COVID-19 needed for single-cell transcriptomic studies is largely inaccessible, and methods to isolate human brain barrier cells have only recently emerged 22 , 23 . (nature.com)
  • The depletion cocktail in this kit does not contain antibodies against CD43, which can be expressed on malignant cells in chronic lymphocytic leukemia (CLL) samples. (stemcell.com)
  • PC-ALCL is one of the primary cutaneous CD30 + T-cell lymphoproliferative disorders, a wide spectrum of disease, with lymphomatoid papulosis (LyP) at the benign end of the spectrum and PC-ALCL at the malignant end. (medscape.com)
  • The achievement, described in the August 6 online issue of Nature Methods , advances not only basic research like biomedical applications of in vitro disease modeling, but may constitute an improved, clinically translatable cell source for replacement strategies in spinal cord injuries and disorders. (disabled-world.com)
  • Across cell types, perturbations associated with COVID-19 overlap with those found in chronic brain disorders and reside in genetic variants associated with cognition, schizophrenia and depression. (nature.com)
  • Abnormalities of red cell membrane cation permeability are seen in several hereditary disorders. (medscape.com)
  • Researchers are expanding a clinical trial to include more patients with mantle cell lymphoma after some patients given the combination of medications under investigation showed no signs of cancer after treatment. (curetoday.com)
  • The CIRLL clinical trial will now be expanded to include additional patients with mantle cell lymphoma (MCL) after it showed promising results in patients with chronic lymphocytic leukemia and six patients with MCL. (curetoday.com)
  • This ulcerated nodule of localized primary cutaneous CD30+ anaplastic large cell lymphoma is relatively nonspecific in appearance. (medscape.com)
  • In 1988, ALCL was added as a distinct entity to the revised Kiel classification, and in 1994, it was included in the Revised European-American Lymphoma (REAL) classification. (medscape.com)
  • When these cells become cancerous, they can overproduce hormones or other biologically active substances that lead to the development of endocrine paraneoplastic syndromes. (healthline.com)
  • IM, nilotinib, or dasatinib, with inhibitors of autophagy resulted in near complete elimination of phenotypically and functionally defined CML stem cells. (lu.se)
  • The results suggest that BPSS0180 may be a novel inducer of host cell autophagy that contributes to B. pseudomallei intracellular growth . (bvsalud.org)
  • We present a rate equation model for the TGF-b pathway in endothelial cells together with novel measurements. (lu.se)
  • endothelial cells. (lu.se)
  • It also provides evidence of the potentially carcinogenic downside to stem cell treatments, and suggests that nature has sought to balance stem cells' regenerative power against their potentially lethal potency. (scienceblog.com)
  • Other paraneoplastic syndromes are caused by cancer cells releasing hormones or other substances. (healthline.com)
  • Many paraneoplastic syndromes are triggered by an abnormal immune response where antibodies or a type of white blood cell called T cells attack and damage healthy cells. (healthline.com)
  • These syndromes can form when your immune system attacks healthy neurological cells. (healthline.com)
  • Thirty-two patients irradiated for LD-SCLC at the University of Lubeck between 2006 and 2014 were included in this retrospective study. (iiarjournals.org)
  • The collaboration pursues an innovative approach to the discovery and development of novel medicines by leveraging Evotec's unique human induced pluripotent stem cell ("iPSC") technology platform, which is one of the largest and most sophisticated platforms in the industry. (evotec.com)
  • Scanning electron micrograph image of cultured human neuron from induced pluripotent stem cell - Image Credit: Mark Ellisman and Thomas Deerinck, National Center for Microscopy and Imaging Research, UC San Diego. (disabled-world.com)
  • A compilation of research experiences in stem cell, viral vector and vaccine production. (corning.com)
  • It also suggests that the premature silencing of the Sept4/ARTS pathway at the stem cell level may herald cancer to come. (scienceblog.com)
  • The transformation from a normal to a cancer cell is driven by the multistep acquisition of genetic alterations. (confex.com)
  • We treat every type of cancer, including the most important one: yours. (mskcc.org)
  • Scientists at MSK are working to understand how cancer cells hide out in the body, sometimes for years at a time. (mskcc.org)
  • Our immune system can detect and kill many metastatic cancer cells, but some escape detection. (mskcc.org)
  • Metastatic cells that haven't yet caused full-blown cancer are hard to study. (mskcc.org)
  • Others are caused by the production of hormones and other biologically active substances by cancer cells. (healthline.com)
  • Humoral hypercalcemia happens when cancer cells cause parathyroid hormone-related molecules to overproduce. (healthline.com)
  • Acromegaly is characterized by the abnormal secretion of growth hormone and insulin-like growth factor 1 by cancer cells. (healthline.com)
  • Including, unfortunately, cancer. (scienceblog.com)
  • Now research from Rockefeller University shows that having too many stem cells, or stem cells that live for too long, can increase the odds of developing cancer. (scienceblog.com)
  • The identification of the ARTS gene and its role in cancer cell death provides a potential target for new therapeutic approaches. (scienceblog.com)
  • Erythrocytes have intracellular hemoglobin, 2-3,diphosphoglycerate (2,3-DPG), and ATP, which all exert osmotic pressure across the semipermeable cell membrane. (medscape.com)
  • By transporting Na + and K + ions across the cell membrane, red cells can adjust the intracellular concentration of these cations and regulate intracellular hydration. (medscape.com)
  • Fig. 1: Overview of diverse brain and choroid plexus cell types captured from post-mortem tissue from patients with COVID-19. (nature.com)
  • For the purpose of this report, the term "electric vehicles" includes commercial approaches such as pure battery-powered, plug-in hybrid, hybrid internal combustion/battery, range extended, and FCVs, as well as vehicles powered by developmental power sources such as supercapacitors and flywheel. (bccresearch.com)
  • The cells are about the same size as GM's gigantic Ultium pouch cells , set to be made at three different plants through the Ultium Cells LLC joint venture with LG. (wpri.com)
  • The expansion of the clinical trial examining this ROR1 inhibitor aims to include more patients with MCL. (curetoday.com)
  • The data files needed by the tests are NOT included in the subversion repository. (lu.se)
  • We also show that individual conjunctival cells can be sorted and reconstituted by cultivation into a functional conjunctival epithelium that includes mucin-producing goblet cells. (listlabs.com)
  • The Corning® Cell Counter uses cloud-based image processing, allowing it to analyze images faster than any existing automated cell counter system. (corning.com)
  • The newly granted "Portable computing device for external fuel cell control," is all of these things, but it's also unusual in how it sets out both the environmental and the political concerns that have prompted it. (appleinsider.com)
  • This newly granted patent is credited to six inventors, all of whom have previous patents in the same field, to do with fuel cell systems specifically for small devices. (appleinsider.com)
  • Tuszynski said that, although more work needs to be done, these newly generated cells will constitute source cells for advancement to human clinical trials on a time frame of three to five years. (disabled-world.com)
  • *Happiness Now Completed also includes a newly re-recorded version of fan favourite Last Chance , with the addition of a full brass section, plus cover versions of Fad Gadget's Back To Nature and X-Ray Spex' s The Day The World Turned Day Glo . (classicpopmag.com)
  • They promoted regeneration after spinal cord injury in adult rats, including corticospinal axons, which are extremely important in human voluntary motor function. (disabled-world.com)
  • It still needs to be determined that the cells are safe over long time periods in rodent and non-human primate studies, and that their efficacy can be replicated. (disabled-world.com)
  • Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines. (hsanmartino.it)
  • This kit isolates untouched and highly purified B-CLL cells directly from human whole blood by fully immunomagnetic negative selection. (stemcell.com)
  • skilled download Cells, Membranes, and Disease, Including Renal, basic concluding of antiquities and invite votes with Prime Video and common more human days. (falken-shop.net)
  • Stem cells have an enormous amount of potential to increase the health, and overall living standards of the human species in general. (scienceblog.com)
  • UN approved 1-gallon pail with Life Latch lid holds up to 25 pounds of dry cell batteries. (1000bulbs.com)
  • Fuel cells differ from batteries, which store electrical energy chemically in a closed system. (technewsworld.com)
  • Another suggests that the stack "may correspond to solid oxide fuel cells, molten carbonate fuel cells, direct methanol fuel cells, alkaline fuel cells, and/or other types of fuel cells. (appleinsider.com)
  • Download our Quality and Regulatory letters, including letters for cGMP compliance. (corning.com)
  • Whole-exome sequencing (WES, mean depth 79x) was performed with 10XGenomics Exome Solution for low DNA-input due to limited numbers of some cell types. (confex.com)
  • We identified four types of fuel cells that could be used in a hydrogen fuel cell storage system. (umass.edu)
  • Because they can propagate indefinitely, as well as give rise to every other cell type in the body (such as neurons, heart, pancreatic and liver cells), they represent a single source of cells that could be used to replace those lost to damage or disease. (evotec.com)
  • Unwanted cells are labeled with antibodies and EasySep™ Direct RapidSpheres™, and separated using an EasySep™ magnet. (stemcell.com)
  • Researchers came up with a single-cell DNA sequencing and immunophenotyping assay for identifying and characterizing AML clones that persist after treatment. (genomeweb.com)
  • That is key because if you look at all the targets that we have right now, they're all expressed on normal cells, which is why we get so many side effects. (curetoday.com)
  • In recent years, much work has been done exploring the potential of using hPSC-derived stem cells to create new spinal cord cells needed to repair damaged or diseased spinal cords. (disabled-world.com)
  • In grafts, these cells could be found throughout the spinal cord, dorsal to ventral. (disabled-world.com)
  • Though the content may have been edited for style, clarity, or length, the article "Spinal Cord Neural Stem Cells Show Diverse Promise for SCI" was originally written by University of California - San Diego, and published by Disabled-World.com on 2018/08/14 (Updated: 2018/08/16). (disabled-world.com)
  • The CLN8 protein is thought to play a role in moving materials in and out of a cell structure called the endoplasmic reticulum . (medlineplus.gov)
  • The endoplasmic reticulum is involved in protein production, processing, and transport to different parts of the cell. (medlineplus.gov)
  • The CLN8 protein may also play a role in helping the endoplasmic reticulum regulate levels of fats (lipids) in cells. (medlineplus.gov)
  • Striking clinical features include frequent cutaneous and extranodal involvement, young age at presentation, and male predominance. (medscape.com)
  • filmic download Cells, Membranes, and Disease, Including Renal algorithms( differently published as First Amendment awards, professional library sovereignties, and speed molecules) begin fighters manipulated aside in other situations for the goal of major generating. (falken-shop.net)
  • Green Car Reports ) - Toyota on Tuesday revealed a prototype hydrogen fuel-cell pickup truck, but it's unclear if the project will progress to a production vehicle. (mystateline.com)
  • Such fuel cells and associated fuels can potentially achieve high volumetric and gravimetric energy densities, which can potentially enable continued operation of portable electronic devices for days or even weeks without refueling. (appleinsider.com)
  • MTI Micro and NeoSolar , a portable device manufacturer known in some markets as "Wibrain," announced a deal Thursday to develop fuel cells for NeoSolar's portable devices including its ultra mobile personal computers (UMPC). (technewsworld.com)
  • Fuel cells consume a reactant, which must be replenished. (technewsworld.com)
  • Fuel cells are a fast developing and market capturing technology that presents efficient means of storing electricity in the form of hydrogen. (umass.edu)
  • Single-cell RNA and B-cell receptor sequencing (scRNA/BCRseq) was performed in total BM B cells and PCs (n=32,720) from 3 IgM MGUS and 2 WM patients. (confex.com)
  • Here we profile 65,309 single-nucleus transcriptomes from 30 frontal cortex and choroid plexus samples across 14 control individuals (including 1 patient with terminal influenza) and 8 patients with COVID-19. (nature.com)
  • b , Uniform manifold approximation and projection (UMAP) of 38,217 nuclei from the medial frontal cortex of 8 control individuals (including 1 patient with influenza) and 8 patients with COVID-19. (nature.com)
  • Among 443 patients included in the study, 122 tion, medical records were reviewed and abstracted into the (28%) were HIV-positive, and of these, 91 (89%) were receiving case record form. (cdc.gov)
  • HIV status was self-reported, persons maintain HIV disease control, including maintaining and patients with unknown status or deemed eligible and ART continuity and adherence, achieving viral suppression, and consented for testing were tested at admission. (cdc.gov)
  • The initial diagnostic evaluation of patients with any lymphoproliferative malignancy should include a careful history and physical examination, with close attention paid to the presence of systemic B symptoms, lymph node involvement, organomegaly, and evidence of cutaneous involvement. (medscape.com)