Incidence protected significantly protected from chemotherapy induced. Medical search. Frequent questions

For example, extracts or purified compounds from Scutellaria barbata, Astragalus membranaceus and Curcuma longa suppressed growth, induced oxidative stress and apoptosis, inhibited breast cancer cell invasiveness and prevented breast cancer metastases in mice ( 11 - 14 ). (spandidos-publications.com)
Compared with low-dose chidamide or bortezomib alone, the low-dose drug combination significantly inhibited the proliferation, migration, and invasion of MGC-803 and BGC-823 cells and induced apoptosis of the cells. (dovepress.com)
ABCG2 inhibitor verapamil, downregulate ABCG2, induce ER stress markers and induces apoptosis. (pka-signal.com)

Given limited effects of chemotherapy and the insensitivity of HCC to radiotherapy, tumor extirpation represents the only choice for a long-term cure. (nature.com)
With the support of various diagnosis technologies including positron emission tomography (PET), magnetic resonance imaging (MRI), and computed tomography (CT), surgery, radiotherapy, chemotherapy, and hormone therapy are generally applied to treat patients with cancer, including those three deadliest carcinomas. (frontiersin.org)
Every one of the enrolled individuals hadn't received chemotherapy or radiotherapy before medical procedures. (insulin-receptor.info)

According to the latest data released by the International Cancer Research Center in 2018, gastrointestinal cancer has the highest incidence and mortality rates among all cancers worldwide. (dovepress.com)
Trends in incidence-based mortality rate (IBMR) were calculated using Joinpoint software. (bvsalud.org)
China may be the largest developing nation, with 98 nearly,900 incident situations and 30,500 mortalities reported in 2018.2 However, the mortality and incidence are increasing year by year. (insulin-receptor.info)
The observed reduced mortality in statin users cannot be explained by lower incidence of CHD death alone. (cdc.gov)

Vogalene® is available under different forms, including 15 mg capsules, 7.5 mg orally disintegrating tablets, 5 mg suppository, 0.1% oral liquid, and a 10 mg/mL intravenous (IV) solution approved for the prevention of chemotherapy-induced nausea and vomiting. (wikipedia.org)
The IV formulation is almost exclusively used to treat chemotherapy-induced nausea and vomiting in adults and children. (wikipedia.org)
Generally, studies in chemotherapy-induced nausea and vomiting suggest that doses of metopimazine higher than approved for common nausea and vomiting conditions tend to be more efficacious while remaining safe and well tolerated. (wikipedia.org)
Ginger (Zingiber officinale) can be helpful in alleviating nausea and vomiting caused by chemotherapy. (peacehealth.org)
Olanzapine, primarily an antipsychotic drug, has been used for nausea/vomiting in palliative care and chemotherapy settings. (apsf.org)
Patients with cancer, a history of chemotherapy-induced nausea and vomiting, and undergoing medium or major surgery were included. (apsf.org)
Secondary outcomes included nausea/vomiting incidence at various time points and severe PONV according to the Clinically Important PONV Intensity Scale. (apsf.org)
Isolated nausea and vomiting in the first 24 hours were also significantly lower in the olanzapine group (10% vs. 53.7%, p=0.002). (apsf.org)
Patients in the olanzapine group had lower nausea and vomiting incidence between 0-6 hours and 0-24 hours postoperatively. (apsf.org)
Cannabis also reduces nausea and vomiting associated with chemotherapy. (healthneu.com)

Jacob et al [ 9 ] examined the association between use of cholesterol-lowering drugs and colorectal cancer incidence among 132,136 men and women in the Cancer Prevention Study II Nutrition Cohort. (biomedcentral.com)
Current or 5 year use of cholesterol-lowering drugs was not associated with colorectal cancer incidence. (biomedcentral.com)
Oxaliplatin (OXA), is a third generation platinum drug used as first-line chemotherapy in colorectal cancer (CRC). (pka-signal.com)
Besides, many Asian countries have experienced an increase of two to four times in the incidence of colorectal cancer during the past few decades (Sung et al. (pka-signal.com)

In a dose-ranging, open-label study in patients undergoing chemotherapy, metopimazine administered orally at 20, 30, 40, 50, or 60 mg every 4 hours (q4h) for 48 hours was used to determine its safety and tolerability. (wikipedia.org)
In a randomized, double-blind study assessing the efficacy and safety of sublingual metopimazine compared to ondansetron in chemotherapy-induced delayed emesis, patients received either 45 mg/day of metopimazine (7.5 mg x 2 every 8 hours) or 16 mg/day of ondansetron (8 mg every 12 hours). (wikipedia.org)
[ 9 ] Gewirtzman et al reported a case of HPV-induced SCC in patients with epidermal dysplasia verruciformis. (medscape.com)
Patients with inoperable head and neck cancer were treated with a spleen peptide preparation (Polyerga) in a double-blind trial during chemotherapy with cisplatin and 5-FU. (peacehealth.org)
In another study, patients receiving high-dose paclitaxel and melphalan had significantly fewer episodes of oral ulcers and bleeding when they took 6 grams of glutamine four times daily along with the chemotherapy. (peacehealth.org)
The extremely low 5-year overall survival of patients is, in part, due to pancreatic cancer cells having several mechanisms of resistance to different chemotherapeutic treatments, one of which is their capacity to efficiently repair alkylating agent-induced DNA damage. (frontiersin.org)
Anticoagulants and thromboprophylaxis can protect patients from this adverse effect. (oncologynurseadvisor.com)
Several risk factors for developing venous thrombosis usually coexist in cancer patients including surgery, hospital admissions and immobilization, the presence of an indwelling central catheter, chemotherapy, use of erythropoiesis-stimulating agents (ESAs) and new molecular-targeted therapies such as antiangiogenic agents. (oncologynurseadvisor.com)
While this study focused on oncology patients, a similar trial in non-oncological gynecological or plastic surgery patients also showed a 39% reduction in PONV incidence in the first 24 hours when olanzapine was added to the regimen. (apsf.org)
The incidence rate for any grade ICIs-related neurologic ir-AEs in patients included in clinical trials has been reported to be approximately 3.8% to 12% [ 20 ]. (hindawi.com)
Better screening, diagnostic and management approaches need to be implemented as a preferred method to protect the liver among patients with DSCs. (bvsalud.org)
Does Transplantation Induce Aging In Patients? (medicaldaily.com)
A number of recent studies have suggested that cancer incidence rates may be lower in patients receiving statin treatment for hypercholesterolemia. (biomedcentral.com)
In addition to the cholesterol lowering effects of statins, a number of recent studies suggest that the cancer incidence rates may be lower in patients receiving statins. (biomedcentral.com)
The Effects of Melatonin on the Descending Pain Inhibitory System and Neural Plasticity Markers in Breast Cancer Patients Receiving Chemotherapy: Randomized, Double-Blinded, Placebo-Controlled Trial is het volledige studierapport vrij in te zien. (kanker-actueel.nl)
Since most patients with HCC are diagnosed at the intermediate or advanced stage and because HCC has a high incidence of metastasis and recurrence, it is one of the leading causes of cancer death. (hindawi.com)

Lung cancer incidences rates in statin users were found to be significantly reduced (55% risk reduction) in the Veterans Affairs (VA) Health Care System case control study [ 5 ]. (biomedcentral.com)

The chemotherapy drug cisplatin may cause excessive loss of magnesium and potassium in the urine. (peacehealth.org)
People receiving cisplatin chemotherapy should ask their prescribing doctor to closely monitor magnesium and potassium status. (peacehealth.org)
Acetyl-L-carnitine in the amount of 1,000 mg three times per day for eight weeks has been shown to improve nerve damage (neuropathy) caused by the chemotherapy drug cisplatin. (peacehealth.org)
Despite this difference, it appears that both carboplatin, USP and cisplatin induce equal numbers of drug-DNA cross-links, causing equivalent lesions and biological effects. (nih.gov)

Studies in animals have revealed that CBD can protect neurons from oxidative stress. (healthneu.com)

In spite of the early diagnosis, radiation and chemotherapy, breast cancer is the second leading cause of cancer death in the United States ( 2 ). (spandidos-publications.com)
Ionizing radiation (therapeutic or accidental) and immunosuppression, such as posttransplantation or with chemotherapy, predispose to SCC by similar mechanisms as sun exposure. (medscape.com)
In fact, animal studies show that glutamine may actually decrease tumor growth while increasing susceptibility of cancer cells to radiation and chemotherapy, though such effects have not yet been studied in humans. (peacehealth.org)
Ashwagandha is also generally considered safe to use with traditional cancer treatments like chemotherapy and radiation. (realrawfood.com)

Any grade CAR-T-related neurologic ir-AEs, by contrast, have the highest incidence. (hindawi.com)

The cumulative incidence function curves were constructed by all causes of death. (bvsalud.org)
Within the first 30 years after diagnosis, survivors of childhood cancers have approximately a 75% cumulative incidence of treatment-related chronic health problems. (ajmc.com)

In particular, the loss of ALKBH6 in human pancreatic cancer cells increases alkylating agent-induced DNA damage and significantly decreases cell survival. (frontiersin.org)
In light of widespread statin consumption and increases in cancer incidence, the association between statins and cancer incidence may be relevant for cancer prevention. (cdc.gov)
As the baby boomers enter their 60s and 70s, we are seeing a population bump that significantly increases the incidence of this age-sensitive cancer. (medscape.com)

Our results suggest that the combination of chidamide and bortezomib can significantly reduce the proliferation, invasion, and migration of MGC-803 and BGC-823 cells, providing a framework for the clinical evaluation of combined therapies for gastric cancers. (dovepress.com)
Though cancer cells use glutamine as a fuel source, studies in humans have not found that glutamine stimulates growth of cancers in people taking chemotherapy. (peacehealth.org)
Statins have been associated with a significantly lower risk of breast (8), colorectal (9), and lymph cancers (10-12) in several observational studies (10,13). (cdc.gov)
Cancers such as doxorubicin are commonly used in cancer leukaemia, colorectal, breast, lung, and so on are chemotherapy. (who.int)

The introduction of Haemophilus influenzae type b conjugate vaccines during the 1990s was followed by dramatic decreases both in the incidence of Haemophilus influenzae type b related invasive disease and in nasopharyngeal carriage of the organism. (bmj.com)

3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) effectively reduce cholesterol levels and decrease the incidence of cardiovascular and cerebrovascular events (4). (cdc.gov)

Evidence has begun to accumulate that these new polysaccharide based conjugate vaccines can also reduce nasopharyngeal carriage and can induce immune responses at the local mucosal level, which may be responsible for these effects. (bmj.com)
This article reviews recent studies on mucosal immune responses induced by polysaccharide based vaccines and some protein vaccine antigens against several pathogenic nasopharyngeal bacteria, and discusses the mechanisms and functions of these immune responses that may help our understanding of mucosal immune responses to both immunisation and infection. (bmj.com)
Recent studies show that parenterally administered capsular polysaccharide (PS) based vaccines can induce mucosal immune responses. (bmj.com)
The cause of oral melanoma or melanoma of any mucosal surface remains unknown, and the incidence has remained stable for more than 25 years. (medscape.com)

Here, we show that BD is not toxic and its oral application significantly suppresses time-dependent increase in tumor sizes and inhibits breast-to-lung cancer metastasis. (spandidos-publications.com)

mRNA and protein expression of ABCG2 and phosphorylation of NF-κB was significantly higher in OXA-R than parental cells. (pka-signal.com)

ABSTRACT In view of the widespread use of pesticides in Egypt and the increasing incidence of leukaemia and lymphoma we aimed to assess pesticide exposure and other selected variables as risk factors for lymphoproliferative disorders (leukaemia and non-Hodgkin lymphoma). (who.int)

In a double-blind trial, intravenous administration of calcium and magnesium before and after administration of oxaliplatin prevented the development of oxaliplatin-induced nerve damage. (peacehealth.org)
However, in another double-blind trial, the same treatment regimen as in the other study did not prevent oxaliplatin-induced nerve damage. (peacehealth.org)
Oxaliplatin (OXA), a first-line chemotherapy in CRC, acts as a bifunctional alkylating agent, covalently binding DNA and forming platinum-DNA adducts to inhibit DNA replication and transcription (Kelland, 2007). (pka-signal.com)

A recent meta-analysis described the incidence of melanoma in 12 qualifying randomized controlled statin trials, with a total of 39,426 participants. (biomedcentral.com)

However, because they induce a T cell independent B cell response, they are poorly immunogenic in young children, and in adults only induce relatively short term protection. (bmj.com)
Caries also occurs in adults, and its incidence appears to increase with age. (medscape.com)

We showed that the intratracheal administration of bvPLA2 markedly suppressed the OVA-induced allergic airway inflammation by reducing AHR, overall area of inflammation, and goblet cell hyperplasia. (blogspot.com)

To date, combinational chemotherapy forms the main part of the treatment strategy for advanced gastric cancer with less than 10% of 5-year survival rate. (dovepress.com)

In a preliminary trial, supplementation with a probiotic (Lactobacillus GG) reduced the frequency of severe diarrhea and the incidence of abdominal discomfort related to the use of 5-FU. (peacehealth.org)
However, the accumulation of evidence suggests that immunotherapy also induces severe and complex neurologic immune-related adverse events (ir-AEs) and even leads to immunotherapy-related death, which arouses the concern of clinicians. (hindawi.com)

Importantly, alkylating agents induce DNA damage at different genomic sites, which subsequently leads to lethal and/or mutagenic DNA base lesions. (frontiersin.org)

The Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS) trial to evaluate the efficacy of lovastatin for preventing coronary events, found a significantly decreased incidence of new melanomas in the lovastatin arm compared with the placebo arm. (biomedcentral.com)

Tumors of sun-protected skin are more prevalent in black persons and Hispanic individuals. (medscape.com)

however, the incidence of gastrointestinal disorders was significantly lower in the metopimazine group, particularly abdominal pain and constipation. (wikipedia.org)

Clinically important PONV incidence in the first 24 hours was significantly lower in the olanzapine group (2% vs. 27%, p=0.015). (apsf.org)
UV-induced photoaging of the skin becomes clinically evident with age, when endogenous antioxidative mechanisms and repair processes are not effective any more and actinic damage to the skin prevails. (researchgate.net)

In a double-blind study, Japanese researchers found that the combination of vitamin E , vitamin C, and N-acetyl cysteine (NAC) -all antioxidants-protected against chemotherapy-induced heart damage without interfering with the action of the chemotherapy. (peacehealth.org)
Although general therapeutic strategies and existent nanomedicine have been applied in relating cancer treatments, the side effects and potential damage induced by the off-target effect greatly lower the therapeutic efficiency. (frontiersin.org)
Several alkylating agents are commonly used in chemotherapy but may induce DNA damage to cancer cells as well as normal cells. (frontiersin.org)

Consistently, the intravenous administration of rhApoAI-PBGD or the hyperfunctional rApoAI-PBGD-I129M/N340S (rApoAI-PBGDms) variant efficiently prevented and abrogated phenobarbital-induced acute attacks in a mouse model of AIP. (unav.edu)

Although research remains incomplete, the idea that people taking chemotherapy should avoid antioxidants is not supported by scientific research. (peacehealth.org)
Akinesia might coexist with any of the other scientific features of extrapyramidal system disease, significantly rigidity, but the presence of akinesia is thought to be an absolute requirement for the analysis of parkinsonism. (ehd.org)

However, the potential mechanism of IF in alleviating dextran sulfate sodium (DSS)-induced colitis is not fully understood. (bvsalud.org)
Transcriptional regulation of voltage-gated sodium channels contributes to GM-CSF induced pain. (iasp-pain.org)

Direct activation of PVA neurons using optogenetics and pharmacological approaches were sufficient to induce persistent mechanical hyperalgesia in naive animals. (iasp-pain.org)
In contrast, optogenetic manipulations of VTA DA neurons revealed their roles in sustaining recurrent scratching episodes through signaling scratching-induced reward. (iasp-pain.org)

The incidence of cancer during pregnancy has increased in recent decades, with doctors facing a complex process of making cancer-obstetric decisions. (medichub.ro)
Peak incidence occurs during the sixth to seventh decades of life. (medscape.com)
The incidence of MCC has been increasing in recent decades. (medscape.com)

We found that the antibody conjugates significantly enhanced the cellular uptake of NPs. (oncotarget.com)
In contrast, occupation was not significantly associated with antibody responses to either MsgA or MsgB. (cdc.gov)

Prior studies involving HCWs used different specimens (e.g., induced sputum, oropharyngeal wash, nasal rinse, deep nasal swab, blood) and different laboratory methods (i.e., different PCR and ELISA) to compare exposed and unexposed groups, making findings difficult to compare across studies ( 25 - 31 ). (cdc.gov)
The best estimates of the incidence of serious pneumococcal disease in the United States are based on surveys and community-based studies of pneumococcal bacteremia. (cdc.gov)
Raadpleeg ook literatuurlijsten gerandomiseerde studies van niet-toxische middelen en behandelingen van arts-bioloog drs. (kanker-actueel.nl)
A series of studies have revealed that exosomes-mediated intercellular transfer of proteins, nucleic acids, and metabolites plays a crucial role in the initiation and progression of HCC, hypoxia and angiogenesis, chemotherapy sensitivity, and cell death mode and regulates the immune microenvironment. (hindawi.com)
autopsy studies show prostate cancer in 15 to 60% of men aged 60 to 90 years old, with incidence increasing with age. (msdmanuals.com)
The noise-induced hearing loss is well known in studies related to the workplace. (bvsalud.org)

Blocking the PPP prevented cholesterol synthesis and thereby HCC in c-Myc mice, while ablating glycolysis did not affect cholesterol synthesis and failed to prevent c-Myc-induced HCC. (nature.com)
Allergic asthma was induced in female BALB/c mice by intraperitoneal administration of ovalbumin (OVA) on days 0 and 14, followed by intratracheal challenge with 1% OVA six times between days 22 and 30. (blogspot.com)

To be effective against colonisation, vaccines must induce local immune responses, which promote elimination of the pathogen, break the chain of transmission, and induce herd immunity. (bmj.com)

A retrospective case series published in the Journal of Alternative and Complementary Medicine found that CBD treatment significantly helped PTSD symptoms, reduced the incidence of nightmares, and improved the patient's condition. (healthneu.com)

In contrast, cutaneous lesions are linked directly to fair-skinned and blue-eyed persons with a history of blistering sunburns, and the incidence has increased dramatically (approximately 4-6% per year) over the same period. (medscape.com)

COCs, the patch, and the ring do not protect against sexually transmitted diseases (STDs), including human immunodeficiency virus (HIV), and women using these methods should be counseled that consistent and correct use of the male latex condom reduces the risk for transmission of HIV and other STDs. (cdc.gov)

The incidence of pneumococcal pneumonia can be 3-5 times that of the detected rates of bacteremia. (cdc.gov)
In fact, incidence rates are similar to those observed in children. (medscape.com)

The rise in PTHrP allows for the rise in calcium while protecting the maternal skeleton. (medscape.com)

While women are more likely to visit a psychiatrist, men are significantly more likely to seek treatment for anxiety disorders, depression, insomnia, or energy depletion. (healthneu.com)
Proper characterization of the pain to identify underlying pathophysiology, which could significantly influence treatment options. (tri-kobe.org)

A comprehensive review of antioxidants and chemotherapy leaves open the question of whether supplemental antioxidants definitely help people with chemotherapy side effects, but it clearly shows that antioxidants need not be avoided for fear that the actions of chemotherapy are interfered with. (peacehealth.org)
This randomized, double-blinded, placebo-controlled trial tested the hypothesis that 20mg of melatonin before and during the first cycle of adjuvant chemotherapy for breast cancer (ACBC) reduced the side effects associated with cognitive impairment. (kanker-actueel.nl)

RESULTS: FHW injuries were significantly lower among the USAF personnel and among females. (cdc.gov)

METHODS: HUVECs were induced by LPS to establish a model of sepsis-induced inflammatory endothelial cell injury. (bvsalud.org)

The extent of this effect has been influenced by the fact that Haemophilus influenzae type b conjugate vaccines reduce nasopharyngeal carriage and induce herd immunity. (bmj.com)

Then in April 2020, a peer-reviewed article showed that honey significantly reduces all pathogens that were investigated in the mouth that cause periodontal disease . (drdanenberg.com)

Vitamin C appears to increase the effectiveness of chemotherapy in animals and with human breast cancer cells in test tube research. (peacehealth.org)

OBJECTIVES: To study the effect of procalcitonin (PCT) on lipopolysaccharide (LPS)-induced expression of the pyroptosis-related proteins nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) and caspase-1 in human umbilical vein endothelial cells (HUVECs). (bvsalud.org)

Female Sprague-Dawley rats implanted with bone cancer cells develop mechanical and thermal hyperalgesia but antagonizing GM-CSF in these animals significantly reduced such hypersensitivity. (iasp-pain.org)

It remains unclear how important this effect is or if people taking chemotherapy should take taurine supplements. (peacehealth.org)

The present study was mainly designed to explore the dynamic changes in the gut microbiota and metabolome after short-term (2 weeks) or long-term (20 weeks) IF and therefore clarify the potential mechanisms by which IF ameliorates DSS-induced colitis in a murine model. (bvsalud.org)

The study found a 60% reduction in PONV incidence in the olanzapine group during the first 24 hours (p=0.008), even though both groups received the recommended multimodal antiemetic regimen. (apsf.org)
This habit in this young population is increasing the risk for the acquisition of music-induced hearing loss, the author of this study noted that 14% of youth surveyed reported risk behavior for acquiring auditory loss 4 . (bvsalud.org)

CBD protects against pathological T-cell invasion after spinal cord injury in the laboratory. (healthneu.com)

Anatomy4

Organisms1

Diseases81

Chemicals and Drugs64

Analytical, Diagnostic and Therapeutic Techniques and Equipment83

Phenomena and Processes13

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena4

Humanities1

Information Science6

Named Groups1

Health Care46

Geographicals3

Apoptosis3

Radiotherapy3

Mortality4

Nausea10

Colorectal cancer4

Patients16

Statin users1

Cisplatin4

Oxidative stress1

Radiation4

Highest incidence1

Cumulative incidence2

Increases3

Cancers4

Decreases1

Statins1

Mucosal4

Lung1

Phosphorylation1

Leukaemia1

Oxaliplatin3

Melanoma1

Adults2

Markedly1

Gastric cancer1

Severe2

Genomic1

Prevention1

Tumors1

Gastrointestinal1

Clinically2

Damage3

Intravenous1

Scientific2

Sodium2

Neurons2

Decades3

Antibody2

Studies6

Mice2

Immune1

Symptoms1

Dramatically1

Diseases1

Rates2

Maternal1

Treatment2

Effects2

Lower1

Methods1

Reduce1

Reduces1

Increase1

Proteins1

Cancer cells1

Important1

Mechanisms1

Study2

Invasion1