BRCA1 ProteinIncidenceGenes, BRCA1BRCA2 ProteinGenes, BRCA2Germ-Line MutationBreast NeoplasmsOvarian NeoplasmsMutationRisk FactorsJewsHeterozygoteGenetic TestingGenetic Predisposition to DiseaseRad51 RecombinaseFounder EffectRetrospective StudiesCohort StudiesBreast Neoplasms, MaleProspective StudiesTime FactorsNeoplastic Syndromes, HereditaryDNA Mutational AnalysisNeoplasm ProteinsFollow-Up StudiesRegistriesDNA RepairGenetic CounselingAge DistributionDNA DamageTreatment OutcomeInfant, NewbornRisk AssessmentRiskNeoplasmsPrevalence