Incidence of radiation induced. Medical search. Frequent questions

Between the first and repeat gamma knife radiosurgery procedures, there was no significant difference in radiologic and symptomatic radiation-induced changes ( P = .35 and P = 1.0, respectively). (ajnr.org)
The risk of symptomatic radiation-induced changes did not increase with retreatment. (ajnr.org)
[5] Another team from the University of Virginia found that the treatment of peripheral lung lesions using RapidArc is dosimetrically equivalent to fixed-gantry IMRT, however, "low dose spillage trended toward improvement, which may reduce the incidence of symptomatic radiation-induced pneumonitis. (varian.com)

Radiation-induced brachial plexopathy can occur when radiotherapy is directed at the chest, axillary region, thoracic outlet, or neck. (medscape.com)
Radiotherapy, the commonly used treatment for thoracic malignant tumor, can lead to severe complications in some patients, like radiation-induced lung injury (RILI). (hindawi.com)
Radiation-induced pneumonitis and lung fibrosis are mostly observed in 4 to 30 weeks and 6 to 12 months after thoracic radiotherapy [ 3 ]. (hindawi.com)
The incidence rate of severe irradiation-induced lung injuries reported is 15% among patients treated by thoracic radiotherapy [ 4 ]. (hindawi.com)
The development of RILI is a potentially fatal toxicity in cancer patients undergoing thoracic radiotherapy for lung or esophageal cancers, or in individuals exposed to ionizing radiation (IR) from a nuclear incident. (drugdiscoverynews.com)
In 1917, the first case was reported of the development of radiation enteritis following the use of radiotherapy to treat malignancy. (medscape.com)
Chicago, IL - November 10, 2009 - Clinicians using RapidArc® radiotherapy technology for fast, precise, non-invasive cancer treatments have found that they are able to substantially reduce scatter dose to surrounding healthy tissues, according to several presentations and posters presented this week at the annual meeting of the American Society for Radiation Oncology (ASTRO) in Chicago. (varian.com)
BACKGROUND: Randomized controlled study was conducted to evaluate the efficacy of Sanyrene® vs. control intervention (DaBao®, a complex of hyaluronic acid and Vitamin E) for acute radiation dermatitis in patients receiving radiotherapy. (bvsalud.org)

Given that breast cancer often is treated with radiation therapy, women experience a greater incidence and prevalence of radiation-induced brachial plexopathy than men. (medscape.com)
Average uranium bedrock concentration in Swedish municipalities predicts male lung cancer incidence rate when adjusted for smoking prevalence: Indication of a cumulative radon induced detriment? (lu.se)
Side effects caused by different drugs affecting the lung tissue are observed increasingly in different patient populations, however incidence and prevalence are poorly understood. (lu.se)

RILI may include early radiation-induced pneumonitis and advanced stage radiation-induced lung fibrosis [ 1 ]. (hindawi.com)
Aqualung scientists identified nicotinamide phosphoribosyltransferase (NAMPT) as a novel upstream immune-based therapeutic target in the development of RILI and have generated a humanized monoclonal therapeutic antibody mAb, ALT-100, which is designed to suppress the systemic inflammatory cascades and prevent radiation pneumonitis and radiation-induced lung fibrosis. (drugdiscoverynews.com)
We are confident that ALT-100/ALT-200 will reduce the severity of potentially fatal radiation pneumonitis and radiation fibrosis. (drugdiscoverynews.com)
However, reports of the incidence of symptomatic radiation pneumonitis ranges from 1-34 percent of patients who receive thoracic radiation for malignancy. (drugdiscoverynews.com)

We conclude that the other epidemiological data do not at present provide clear evidence of a risk of circulatory diseases at doses of ionizing radiation in the range 0-4 Sv, as suggested by the atomic bomb survivors. (bioone.org)

This is due to the radiobiological effects of radiation therapy continuing even after a treatment course has ended. (eviq.org.au)
This statement concerned the efforts of NIOSH to protect workers against the hazardous effects of radiation exposure, particularly radiation induced carcinogenesis. (cdc.gov)
The direct effects of radiation on the bowel mucosa lead to acute radiation enteritis. (medscape.com)
The development of improved dosimetry techniques, as well as patient selection and positioning during delivery of RT, were crucial to decrease the harmful effects of radiation on the intestines. (medscape.com)
A study in women with breast cancer found that drinking red wine can help limit the toxic effects of radiation therapy. (nbcnews.com)
It's already known that some wine components may protect against the harmful effects of radiation. (nbcnews.com)
Eight employees and $50,000, 'For research in cancer and the effects of radiation. (jax.org)

Results from the English National Cancer Survivorship initiative, which includes a study on the consequences of treatment in adult cancer, such as radiation-induced brachial plexopathy, suggest that patients benefit significantly when the prevention, detection, and treatment of some of these consequences are approached systematically. (medscape.com)
RID is common and can affect up to 90% of patients receiving radiation therapy, especially in patients being treated for breast cancer, head and neck (H&N) cancer, skin cancer, lung cancer and sarcoma. (eviq.org.au)
Exposure to UV radiation during childhood plays a role in the future development of skin cancer. (cdc.gov)
Because a substantial percentage of lifetime sun exposure occurs before age 20 years ( 2,3 ) and because ultraviolet (UV) radiation exposure during childhood and adolescence plays an important role in the development of skin cancer ( 2,4 ), preventive behaviors can yield the most positive effects, if they are initiated early and established as healthy and consistent patterns throughout life. (cdc.gov)
Exposure to ionizing radiation is known to increase the future incidence of cancer, particularly leukemia. (wikipedia.org)
Non-ionizing radio frequency radiation from mobile phones, electric power transmission, and other similar sources have been investigated as a possible carcinogen by the WHO's International Agency for Research on Cancer, but to date, no evidence of this has been observed. (wikipedia.org)
According to the prevalent model, any radiation exposure can increase the risk of cancer. (wikipedia.org)
Epidemiological evidence shows a clear link between lung cancer and high concentrations of radon, with 21,000 radon-induced U.S. lung cancer deaths per year-second only to cigarette smoking-according to the United States Environmental Protection Agency. (wikipedia.org)
Radiation is a more potent source of cancer when it is combined with other cancer-causing agents, such as radon gas exposure plus smoking tobacco. (wikipedia.org)
This estimate is criticized by the American College of Radiology (ACR), which maintains that the life expectancy of CT scanned patients is not that of the general population and that the model of calculating cancer is based on total-body radiation exposure and thus faulty. (wikipedia.org)
In addition to conventional fatalities and acute radiation syndrome fatalities, nine children died of thyroid cancer, and it is estimated that there may be up to 4,000 excess cancer deaths among the approximately 600,000 most highly exposed people. (wikipedia.org)
For ophthalmol-ogists, this stricter standard suggests that a new level of vigilance should be employed for certain patients, notably medical colleagues whose work involves radiation, said the panel's cochair, Lawrence T. Dauer, PhD, at Memorial Sloan Kettering Cancer Center in New York City. (aao.org)
Data were gathered concerning hazards from radon daughter products among uranium mining and milling operations including the increased incidence of lung cancer. (cdc.gov)
All radiation doses carry a finite risk of inducing cancer or genetic disorders in the foetus. (iaea.org)
Advances in cancer research in the last few decades has now resulted in cure at the early stages of Hodgkins lymphoma by radiation and in the later stages by combination therapy (radiation with chemotherapy). (medindia.net)
There are currently no FDA-approved therapies for patients who experience radiation-induced lung injury and we believe our preclinical evidence is compelling and supports the advancement of ALT-100/ALT-200 as a potential therapy for patients with thoracic cancer and potentially for individuals accidentally exposed in a nuclear incident. (drugdiscoverynews.com)
Several studies have found that the incidence of thyroid cancer among children in Belarus, Ukraine and Russia has risen sharply. (mongabay.com)
Late in 1995, the World Health Organisation linked nearly 700 cases of thyroid cancer among children and adolescents to the Chernobyl accident and among these some 10 deaths are attributed to radiation. (mongabay.com)
NEW YORK (Reuters Health) - Cancer patients undergoing radiation treatment may want to sip some red wine before treatment. (nbcnews.com)
In the current study, Macchia and colleagues evaluated the potential protective effects of varying levels of self-reported red wine consumption in 348 women treated with radiation therapy after breast cancer surgery. (nbcnews.com)
If wine can prevent (radiation)-induced toxicity without affecting antitumor efficacy, as we observed, it also has the potential to enhance the therapeutic benefit in cancer patients without increasing their risk of serious adverse effects," Macchia said. (nbcnews.com)
It can be classified as primary or secondary, the latter being more common in those who have previously had radiation therapy for breast cancer and is associated with persistent lymphoedema . (klarity.health)
Radiation therapy is critical in the treatment of breast angiosarcoma, a rare and aggressive cancer that arises from the blood vessels of the breast. (klarity.health)
Patients who have had chemotherapy or radiation therapy for breast cancer or other malignancies have a greater likelihood of developing angiosarcoma in the radiated area. (klarity.health)
Machine learning algorithms were used to analyze the odds and predictors of complications of thyroid damage after radiation therapy in patients with head and neck cancer. (bvsalud.org)
This study found that five predictors (age, thyroid volume, mean dose, V50 and V60) are important factors affecting the chance that patients with head and neck cancer who received radiation therapy will develop hypothyroidism. (bvsalud.org)
Changes associated with irradiation cystitis, which developed after 7200cGy external beam radiation for localized prostate cancer. (medscape.com)
On the basis of these data and reports indicating that patients with HPV-positive cancer have their first sexual experience at a young age and have multiple partners, we postulate that increased incidence of OSCC in the United States and some countries in northern Europe is because of a new, primarily sexually transmitted HPV epidemic. (cdc.gov)
In many countries, vaccines against some human papillomavirus (HPV) types are now administered to girls and young women with the goal of protecting them against HPV-induced cervical cancer ( 1 , 2 ). (cdc.gov)
We focus on the role of HPV in the increased incidence of oropharyngeal squamous cell carcinoma (OSCC), the head and neck cancer in which HPV is most commonly found ( 4 ). (cdc.gov)
It is the most common form of cancer in India, and incidence is higher in countries in Latin America than in the United States and northern Europe. (cdc.gov)
RESULTS-- We identified 120 137 childhood and adolescent cancer cases during 2001-2009 with an age-adjusted incidence rate of 171.01 per million. (cdc.gov)
NPCR) and Surveillance, Epidemiology, and End Results (SEER) data, Li et al3 demonstrated regional differences in the incidence of childhood cancer and that the incidence varied by age, gender, and race. (cdc.gov)
Her research programme focuses on solar ultraviolet and visible radiation beneficial and adverse effects on human skin, particularly sunburn inflammation, the photodermatoses, vitamin D synthesis, and the development of photoprotective measures including dietary and hormonal (aMSH analogue) agents and phototherapies including photodynamic therapy for skin cancer. (manchester.ac.uk)
The aim of this study is to evaluate the dosemetric parameters and acute toxicity of dose-escalated whole pelvis (WP) Intensity Modulated Radiation Therapy (IMRT) and volumetric modulated arc therapy (VMAT) prostate boost following neoadjuvant and concomitant with androgen deprivation therapy in high-risk prostate cancer patients. (scirp.org)
In a Phase III trial, The Radiation Therapy Oncology Group (RTOG) showed improved progression-free survival (PFS) for high-risk prostate cancer patients treated with Whole Pelvis Radiation Therapy (WPRT) compared with prostate-only radiation therapy (PORT) [4]. (scirp.org)
Hence, there is increased interest in radiation dose escalation combined with androgen deprivation in high risk prostate cancer patients [6] [7]. (scirp.org)
There is fear circulating about the risk of lung cancer due to inhaled radon gas, as a result of the widespread publicity given to studies that link lung cancer incidence to radon concentration using a "linear no-threshold" (LNT) model. (acsh.org)
Little publicity, however, has been given to the studies that actually measured home radon levels and examined the lung cancer incidence of the residents. (acsh.org)
Dr. Jerry M. Cuttler, a radiation expert and advisor to the American Council on Science and Health, has co-authored a paper entitled "Threshold for Radon-Induced Lung Cancer From Inhaled Plutonium Data," along with Charles L. Sanders. (acsh.org)
Dr. Cuttler points out that measured radon levels and cancer outcomes document, in fact, a significant decrease below the natural incidence of lung cancer. (acsh.org)
As I researched, I was alarmed to find studies done in the United States, Europe and Australia concluding that mammograms were not only ineffective in detecting cancer but, worse still, may result in radiation-induced cancer. (straitstimes.com)
There was no drop in the incidence of invasive breast cancer after detection and removal of DCIS. (straitstimes.com)
The incidence of keratinocyte cancer (basal cell and squamous cell carcinomas of the skin) is 17-fold lower in Singapore than the UK, despite Singapore receiving 2-3 times more ultraviolet (UV) radiation. (cdc.gov)
We hypothesized that differences in keratinocyte cancer incidence may be reflected in the normal skin mutational landscape. (cdc.gov)
Primarily based on these findings, the International Agency for Research on Cancer (IARC) at the World Health Organization (WHO) classified in May, 2011 RF radiation at the frequency range of 30 kHz‑300 GHz as a 'possible' human carcinogen, Group 2B. (spandidos-publications.com)
There is some evidence of an increased risk of developing thyroid cancer, and clear evidence that RF radiation is a multi‑site carcinogen. (spandidos-publications.com)
In May, 2011 the International Agency for Research on Cancer (IARC) concluded that radiofrequency (RF) radiation in the frequency range 30 kHz-300 GHz is a 'possible' human carcinogen Group 2B ( 7 , 8 ). (spandidos-publications.com)
L. C. Dunn breeds Strain 129, which later proves to have a high incidence of testicular cancer. (jax.org)
The mechanistic data for all types of can be used to identify and organize fects (e.g. is able to induce genotox- ionizing radiation ( IARC, 2012f) are mechanistic information related to icity or affect similar pathways), but particularly informative with regard to cancer induction. (who.int)
The classic organ systems are influenced by ters DNA repair or causes genomic mutation theory of cancer no longer mechanistic events associated with instability, (4) induces epigenetic fully encompasses the mechanistic cancer induction. (who.int)

Severe radiation-induced lung toxicity, expected at normal lung absorbed doses of 25-27 Gy, is avoided, probably because most of the local electron dose is delivered to tumor tissue instead of to normal lung parenchyma. (snmjournals.org)
The possibility that particular dietary practices or interventions can reduce radiation-induced toxicity is very intriguing," Dr. Gabriella Macchia, of Catholic University, Campobasso, Italy, noted in an email to Reuters Health. (nbcnews.com)
The incidence of radiation-induced skin toxicity greater was 38.4 percent in non-drinkers, 31.8 percent in women drinking only half a glass of wine daily, 13.6 percent in those drinking one glass daily, and 35 percent in those drinking two glasses daily. (nbcnews.com)
The Proctitis and frequency were the commonest acute toxicity and were maximal during the 5th week of radiation therapy. (scirp.org)
Mechanisms are not fully elucidated and several hundreds of various types of drugs are able to cause the type of toxicity and injury, called Drug-induced interstitial lung disease (DIILD). (lu.se)

Radiation therapy (RT) is a mainstay in the treatment of both primary and recurrent gastrointestinal (GI) and pelvic malignancies. (medscape.com)
Because RT is increasingly used to treat pelvic malignancies, the surgical prevention and treatment of the complications of radiation enteritis and proctitis continue to evolve. (medscape.com)
Background: Radiation-induced pelvic insufficiency fracture (PIF) is an important complication associated with pelvic radiation therapy (RT) for patients with gynecologic malignancies. (harvard.edu)
9 Secondary radiation-induced malignancies can occur decades after the initial radiation treatment. (appliedradiationoncology.com)
11 Mohs micrographic surgery is also considered the first-line treatment for skin malignancies previously treated with radiation, and should be considered in future cases. (appliedradiationoncology.com)

The goal: to reduce the incidence of radiation-induced cataracts. (aao.org)

The essential molecular interactions of the different HPV oncoproteins to induce cervical carcinogenesis are now better understood. (who.int)
Although host susceptibility stress, (6) induces chronic inflam- benzene) that induce not only muta- factors have a modulating role in mation, (7) is immunosuppressive, tions but also a variety of epigenetic carcinogenesis and can affect un- (8) modulates receptor-mediated changes. (who.int)

While dosing regimens are designed to limit damage to healthy tissue, radiation-induced neuropathy may occur. (medscape.com)
The panel noted that there has been a gradual realization in recent years that radi-ation-induced cataracts can occur at much lower, chronic dose levels than was previously thought. (aao.org)
Radiation-induced changes can occur after stereotactic radiosurgery for brain AVMs, potentially causing symptomatic complications. (ajnr.org)
When the first procedure fails to achieve complete AVM obliteration, a favorable outcome can be achieved by a repeat gamma knife radiosurgery, even if radiation-induced changes occur after the first treatment. (ajnr.org)

Less quantity of transplanted mesenchymal stem cells (MSCs) influences the therapeutic effects on radiation-induced lung injury (RILI). (hindawi.com)
Radiation-induced lung injury: Is there finally an approved treatment on the way? (drugdiscoverynews.com)

8 The site of previous radiation is at highest risk of radiation-induced secondary malignancy due to the high therapeutic radiation doses administered. (appliedradiationoncology.com)

9 The documented link between previous radiation and developing MAC suggests that mutagenesis caused by radiation treatment for this patient's squamous cell carcinoma likely contributed to the development of syringomatous carcinoma. (appliedradiationoncology.com)
This report presents a unique case of likely radiation-induced syringomatous carcinoma in a patient previously treated with radiation for a left intranasal squamous cell carcinoma. (appliedradiationoncology.com)

r r Radiation induced fibrosis (RIF) resulting from chronic dermatitis can manifest in many ways such as skin induration (the skin becoming thicker and harder due to an inflammatory process induced by radiation) and retraction/inversion (skin scarring resulting in pulling of the nearby skin), lymphoedema and restriction of joint motion. (eviq.org.au)

Phan C, Mindrum M, Silverman C, Paris K, Spanos W. Matched-control retrospective study of the acute and late complications in patients with collagen vascular diseases treated with radiation therapy. (medscape.com)
The surgical treatment of radiation-induced carotid stenosis is challenging and presents a high rate of complications. (citationimpact.com)

Our results show that lsm1 Δ increases the UV-radiation sensitivity of the rad1 Δ and rad51 Δ mutants, but not the rad18 Δ mutant, placing LSM1 within the post-replication repair/damage tolerance pathway (PRR). (bioone.org)
When combined with other deletions affecting PRR, lsm1 Δ increases the UV-radiation sensitivity of the rev3 Δ, rad30 Δ and pol30-K164R mutants but not rad5 Δ. (bioone.org)
Adjuvant radiation treatment reduces the likelihood of local recurrence and increases overall survival rates. (klarity.health)
From 1975-2001, a rapid and steady increase occurred in the incidence of ocular NHL, with annual increases of 6.2% and 6.5% among White males and White females, respectively. (medscape.com)
The incidence of ocular lymphoma increases with advancing age. (medscape.com)

Chronic RID is a late side-effect of skin irradiation typically presenting months to years after radiation exposure. (eviq.org.au)
r Some patients may develop late skin effects (chronic RID) months to years after the exposure to radiation therapy. (eviq.org.au)
Chronic radiation enteritis is an indolent but relentlessly progressive disease. (medscape.com)
Chronic intestinal radiation injury is a result of transmural bowel damage with associated obliterative endarteritis. (medscape.com)

In 1930, researchers reported the development of factitial proctitis in a group of patients who received pelvic radiation to treat malignant disease. (medscape.com)
Noninfectious hemorrhagic cystitis most commonly occurs in patients who have undergone pelvic radiation (see the image below), chemotherapy, or both. (medscape.com)

Although the benefits of treatment with radiation are well established, damage to the healthy, nonneoplastic tissue may be severe. (medscape.com)

citation needed] Additionally, the vast majority of non-invasive cancers are non-melanoma skin cancers caused by ultraviolet radiation (which lies on the boundary between ionizing and non-ionizing radiation). (wikipedia.org)
Hazards from exposure to ultraviolet radiation included eye and skin damage , hyperpigmentation and skin cancers. (cdc.gov)

The RapidArc treatments also use much fewer monitor units-a two to three-fold decrease-which means that less scattered, non-therapeutic radiation is delivered during these treatments, which took, on average, 1.25 minutes to deliver once patients were positioned for treatment. (varian.com)
5-7 Exposure to radiation, whether therapeutic or otherwise, causes changes in the DNA of normal tissues, which can lead to tumorigenesis. (appliedradiationoncology.com)

In in vivo and in vitro studies, MSCs were found to alleviate irradiation-induced lung injuries not only by the secretion of cytokines, growth factors, and paracrine molecules but also by immunomodulatory effect. (hindawi.com)
On the other hand, both the ectopic and entopic expression of ΔNp63α in apoptosis-sensitive hiPSCs reduced the expression levels of BAX after irradiation and significantly decreased the number of apoptotic cells induced by radiation. (researchsquare.com)

The DXA doses are such that these risks are small by comparison with the natural incidence of these conditions. (iaea.org)

The DNA damage response (DDR) is a mechanism that protects cells against radiation-induced oxidative DNA damage by causing cell cycle arrest and apoptosis. (researchsquare.com)
Ionizing radiation is well known to induce oxidative DNA damage, such as DNA double-strand breaks (DSBs), and consequently trigger the DNA damage response (DDR), including cell cycle arrest and apoptosis. (researchsquare.com)
The DNA guardian protein p53 plays the most important role in DDR: it promotes DNA repair and the elimination of cells that are unable to repair the damage caused by oxidative stresses, including radiation. (researchsquare.com)
alterations, (5) induces oxidative data for several carcinogens (e.g. (who.int)

Radiation-induced dermatitis (RID) is a cutaneous reaction that occurs because of damage by ionising radiation. (eviq.org.au)
Reference 'Oral green tea catechin metabolites are incorporated into human skin and protect against UV radiation-induced cutaneous inflammation in association with reduced production of pro-inflammatory eicosanoid 12-hydroxyeicosatetraenoic acid. (herbalmusings.com)

The current incidence is 1-2% in patients receiving a typical dose of less than 55 Gy. (medscape.com)
No sources in the literature have examined the racial or ethnic distribution of patients with radiation-induced brachial plexopathy. (medscape.com)
r Regarding superficial radiation therapy (kilovoltage [kV] photon energy and some electron treatments), acute reactions, such as erythema, skin breakdown and mild discomfort are common side-effects experienced by most patients. (eviq.org.au)
After the first treatment, radiologic radiation-induced changes developed in 48 (32%) patients, eight of whom had symptomatic changes. (ajnr.org)
Radiation-induced changes occurred in only 5 (20%) patients who underwent a second gamma knife radiosurgery, one of whom experienced transient neurologic deficits. (ajnr.org)
Observation, surgery, and radiation all are considered among the potential treatments when evaluating patients with meningioma. (medscape.com)
Pulmonary radiation injury manifests in approximately 8 percent of patients who receive thoracic radiation. (drugdiscoverynews.com)
We describe our recent experience in the endovascular treatment by means of stent-assisted angioplasty with the aid of a filter cerebral protection device of eight patients presenting with radiation-induced carotid stenosis. (citationimpact.com)
Androgen deprivation therapy (ADT) was given for all patients before and during radiation therapy. (scirp.org)
Development of a closely related neoplasm, MAC, however, has been linked to patients who previously received radiation treatment. (appliedradiationoncology.com)
Characteristics of radiation-induced meningiomas include an average latent period of 36-38 years for patients who were exposed to low-dose radiation to the head, whereas patients who develop meningiomas after exposure to high-dose radiation may show signs as early as 5 years postradiation. (medscape.com)

Wong best defines it, in 1997 as a slow-healing radiation-induced ischemic necrosis of variable extent occurring in the absence of local primary tumor necrosis, recurrence, or metastatic disease 2 . (bvsalud.org)

Advanced age may be a risk factor for the development of brachial plexopathy after radiation treatment. (medscape.com)
Typical contributors to such risk include natural background radiation, medical procedures, occupational exposures, nuclear accidents, and many others. (wikipedia.org)
Women who drank only one glass daily had a much lower risk of suffering skin effects from radiation therapy. (nbcnews.com)
One of the most important risk factors for breast angiosarcoma is prior radiation therapy. (klarity.health)
Despite known risk factors and recent reports describing the incidence on the order of 30 percent, there has been a dearth of translational research or consensus statements to guide clinical management. (harvard.edu)
A computerized electronic literature search was performed using Medline, for articles published from January 2000 to November 2011 on ORN and its incidence, classification, risk factors, physiopathology, and prevention. (bvsalud.org)
Radiation hormesis and adaptive response provide a new scope in the risk assessment and medical application of ionizing radiation. (go.jp)
Previous studies demonstrated the superiority of IMRT over the conventional radiation techniques for WPRT in sparing of organs at risk [9] and superior target coverage [10]. (scirp.org)
In this regard, radiation therapy and accidental exposure to gamma (γ)-ray radiation have been shown to inhibit bone formation and increase the risk of fractures. (biomedcentral.com)

Although radiation therapy is used in the treatment of a myriad of neoplastic diseases, it has potentially adverse effects on several organs and systems that are exposed during treatment. (medscape.com)
When treating the axillary and supraclavicular lymph nodes with radiation therapy, it is impossible to avoid irradiating normal tissues, including the brachial plexus. (medscape.com)
Most commonly, the plexopathy develops months to years after radiation therapy and demonstrates a relatively stable course over months to years with a gradual worsening of paresthesias and pain. (medscape.com)
It typically occurs gradually during a fractionated course of radiation therapy, with the time of onset varying from days to weeks after starting treatment. (eviq.org.au)
r Ongoing damage to the skin cells during a course of radiation therapy stops skin cells from repairing and replenishing. (eviq.org.au)
Usually, acute skin reactions begin to resolve within a month after completion of radiation therapy. (eviq.org.au)
Previous radiation therapy to the same area. (eviq.org.au)
Those with a smaller tumor volume and no prior radiation therapy were more likely to have a favorable response after radiosurgery. (thejns.org)
Zinc may help reduce some symptoms caused by radiation therapy. (mskcc.org)
The reduction in treatment time is a benefit to image-guided radiation therapy (IGRT) and consequently to SBRT," the researchers assert. (varian.com)
Furthermore, radiation therapy is frequently used as an additional treatment after surgery, which is known as adjuvant radiation therapy. (klarity.health)
Radiation therapy can also be used as a neoadjuvant procedure before surgery. (klarity.health)
Adjuvant oncologic therapy such as radiation therapy to the site of the lesion is known to increase development or progression of carotid stenosis. (bvsalud.org)
What are the principles of radiation therapy in the definitive management of stage III inoperable NSCLC? (cancer.org.au)
Improved accuracy in target volume delineation and radiation therapy delivery has the potential to improve treatment outcomes in NSCLC by facilitating radiation dose escalation and ensuring geographic misses are avoided. (cancer.org.au)
Dose escalation can be achieved with either 3-Dimensional Conformal Radiation Therapy (3-DCRT) or with intensity-modulated Radiation Therapy (IMRT). (scirp.org)
The patient was not considered a good candidate for further radiation therapy primarily due to previous radiation and the relatively indolent nature of her disease. (appliedradiationoncology.com)

SOURCE: International Journal of Radiation Oncology Biology and Physics, 2009. (nbcnews.com)
Physics and imaging in radiation oncology. (lu.se)
Gamma (γ)-rays are highly penetrating electromagnetic ionizing radiation that have been extensively applied in diagnostic radiography, radiation oncology, and military weapons [ 1 ]. (biomedcentral.com)

virtually every patient has some manifestation of acute radiation-induced injury of the GI tract in the form of abdominal cramping, tenesmus, urgency, bleeding, diarrhea, and incontinence. (medscape.com)
203 people were hospitalized immediately, of whom 31 died (28 of them died from acute radiation exposure). (mongabay.com)
Acute radiation toxicities were reported during the radiation course and the following 3 months. (scirp.org)

The frequency of radiation-induced brachial plexopathy has declined over the past 60 years and depends significantly on both the radiation dose and the proximity of the radiation volume to the underlying plexus. (medscape.com)
The development of radiation-induced changes after the first treatment was significantly associated with successful obliteration by subsequent radiosurgery (OR = 24.0, 95% CI 1.20-483, P = .007). (ajnr.org)
While applying green tea formulations topically is certainly beneficial to the skin, this team of researchers found that consuming 540 mg of green tea extract each day for three months significantly reduced the incidence of sunburn in more than a dozen fair-skinned men and women. (herbalmusings.com)

Conclusion: Radiation-induced PIF remains an important complication associated with pelvic RT. (harvard.edu)

Acute RID is defined as dermatitis occurring within 90 days of exposure to ionising radiation. (eviq.org.au)
In clinical practice, the use of an assessment tool can aid in the assessment of a patient's skin reaction, for example, the eviQ radiation-induced dermatitis assessment tool . (eviq.org.au)
The primary endpoint was incidence rate of ≥ grade 2 radiation induced dermatitis. (bvsalud.org)

Studying 228 birds of 23 different species captured in Chernobyl, Gaschak and colleagues from the University of South Carolina (US) and University Pierre et Marie Curie (France) measured the birds' levels of radioactive strontium and radioactive cesium, comparing migrating populations with those that remain in the area, as well as examining age, sex, and nesting preferences to determine the amounts and types of radiation accumulating in the birds. (mongabay.com)

Vismodegibfor the treatment of radiation-induced basal cell carcinoma - a case report and brief literature study. (medindia.net)

Transfection with CXCR4 enhanced the quantity of transplanted HUMSCs in the radiation-induced injured lung tissues. (hindawi.com)
Given its high calcium content, bone tissue is sensitive to ionizing radiation and absorbs nearly 40% more radiation than the surrounding tissues [ 2 ]. (biomedcentral.com)

This p53-repressive activity may cause genomic instability in epithelial stem cells exposed to radiation. (researchsquare.com)
Taken together, these results indicate that ΔNp63α represses p53-related radiation-induced DDR, thereby potentially causing genomic instability in epithelial stem cells. (researchsquare.com)

Surgery is the primary form of treatment because it gives the most effective local control, whereas radiation and chemotherapy can be less effective and have more side effects. (klarity.health)

Structural tissue damage, free radicals, the inflammatory response and irreversible DNA damage may all contribute to changes to involved skin during radiation treatment. (eviq.org.au)

Airline crews receive occupational exposures from cosmic radiation because of reduced atmospheric shielding at altitude. (wikipedia.org)
1 (On average, Ameri-cans receive about 6 mSv of radiation per year from naturally occurring and medical exposures. (aao.org)
Exposures of airport personnel working with baggage x-ray inspection units were deemed to be well below the OSHA exposure standard and the radiation hazard to these workers was classified as minimal. (cdc.gov)
Recent analyses of mortality among atomic bomb survivors have suggested a linear dose-response relationship between ionizing radiation and diseases of the circulatory system for exposures in the range 0-4 Sv. (bioone.org)

We evaluated the incidence of such changes and the efficacy of repeat gamma knife radiosurgery for incompletely obliterated AVMs. (ajnr.org)
Radiation-induced changes after the first gamma knife radiosurgery were associated with AVM obliteration after a repeat procedure. (ajnr.org)

Based on the Preamble to the IARC Monographs, RF radiation should be classified as carcinogenic to humans, Group 1. (spandidos-publications.com)
IARC at the World Health Organization (WHO) is independently financed and has its own governing and scientific councils, which WHO staff only attend as observers ( http://www.who.int/ionizing_radiation/research/iarc/en/ ). (spandidos-publications.com)
In fact, WHO seems to rely on the conclusion of the non-governmental organization International Commission on Non-ionizing Radiation Protection (ICNIRP) instead of the IARC evaluation. (spandidos-publications.com)

2016) discovered that neoadjuvant radiation treatment was beneficial in downstaging the tumour and boosting the rate of full surgical resection. (klarity.health)
The microbiome may lack statistical power to detect common, tumour site concordances can also play a critical part in host an increase in tumour incidence at among the species studied. (who.int)

The incidence of melanoma has increased 150%, and melanoma mortality rates have increased by 44% ( 1 ). (cdc.gov)
Considerable uncertainties remain as to the incidence and mortality due to congenital disorders, especially in countries which lack adequate registration of deaths. (who.int)

In addition to the patient's ineligibility for further radiation, syringomatous carcinomas are thought to be resistant to radiation due to their slow-growing nature. (appliedradiationoncology.com)

This is a joint project with the department of Medical Radiation Physics, Lund at Lund University. (lu.se)

and underlying comorbidities such as diabetes, hypertension, obesity, and vascular disease all demonstrate significant association with the development of radiation injury to the brachial plexus. (medscape.com)
The natural course of radiation injury to the brachial plexus varies. (medscape.com)

Approximately 65%--90% of melanomas are caused by ultraviolet (UV) radiation. (cdc.gov)

Hormesis applies to radiation, too. (acsh.org)
Dr. Cuttler has asserted that no harmful health effects have ever been detected in high natural radiation background areas, most notably (for the American Council, anyway) in his publication , "Nuclear Energy and Health, and the Benefits of Low-level Radiation Hormesis . (acsh.org)

Workers were potentially exposed to radiofrequency and microwave radiation from a large number of devices including radio and radar transmitters, industrial dryers, heat sealing and curing equipment and certain medical research devices. (cdc.gov)

This study suggested that melatonin could protect CBSCs against γ-ray radiation and assist in the healing of postradiation bone defects. (biomedcentral.com)

Carotid angioplasty with cerebral protection can be performed safely in radiation-induced carotid stenosis with a high technical success rate. (citationimpact.com)
More generally, skin adnexal carcinomas have an incidence rate of 5.1 per 1 million person-years. (appliedradiationoncology.com)

Specifically, the study subjects experienced less UV radiation-induced inflammation and evidenced intact catechin metabolites in skin tissue and fluid. (herbalmusings.com)

It is the LNT model which has popularized the common myth that radiation is unsafe at any dose, despite the frequent counterpoints by nuclear experts such as renowned Swedish radiobiologist Gunnar Walinder. (acsh.org)
S133 raw or inadequately treated sewage is used caused by malnutrition induced by unsafe in an unregulated manner. (who.int)

Initial changes to the skin such as erythema usually appear 2-3 weeks following the start of radiation treatment. (eviq.org.au)
First and foremost, radiation treatment is successful in controlling local tumours. (klarity.health)
Several studies have found that radiation treatment is effective in treating breast angiosarcoma. (klarity.health)
Adjuvant radiation treatment, for example, was linked to enhanced local control and healthy rates of survival in research by Italiano et al. (klarity.health)
Then CBSCs were subjected to 6 Gy γ-ray radiation followed by treatment with various concentrations of melatonin. (biomedcentral.com)
Treatment involved 61 Gy in 25 daily fractions using the parallel-opposed pair (POP) technique with 4 MV. The radiation field covered the left nose with superior margin falling off the nose, onto the upper lip, and including the left nasolabial fold and septum. (appliedradiationoncology.com)

In the 1950s, the incidence was as high as 66% after 60-Gy total dosing to the axillary and supraclavicular area using 5 Gy/fraction. (medscape.com)
The concept was extended and applied to ionizing radiation, high doses of which are harmful. (go.jp)
Although radiation has been thought to be, based on findings in high dose ranges, harmful no matter low the dose is, recent investigation revealed that living organisms possess the ability to respond to low-dose radiation in very sophisticated ways. (go.jp)
The adaptive response is effective for chromosome induction, acute death, and tumorigenesis induced by high doses of radiation. (go.jp)
Arbitrary standards such as these ignore thousands of studies disproving LNT and demonstrating radiation s hormetic effect that a "toxic" exposure at high levels can be beneficial at lower doses. (acsh.org)
I began to question why the incidence of further tests was so high just among my small circle of friends. (straitstimes.com)
Maternal illnesses like diabetes mellitus, conditions such as iodine and folic acid deficiency, and exposure to medicinal and recreational drugs including alcohol and tobacco, certain environmental chemicals, and high doses of radiation are other factors that cause birth defects. (who.int)

The incidence of lymphoproliferative ocular diseases, especially malignant lymphoma, has increased over the years. (medscape.com)
An increased incidence of glioma in the brain and malignant schwannoma in the heart was found in the US National Toxicology Program (NTP) study on rats and mice. (spandidos-publications.com)

The biological mechanisms of an acquired radioresistance induced by a priming exposure to 0.45 Gy in C57BL/6 mice have been studied. (go.jp)
However, the mechanisms of radiation-induced bone loss at the cellular level are yet to be fully elucidated. (biomedcentral.com)

Other studies allowing a comparison of the rates of circulatory disease in individuals drawn from the same population but exposed to ionizing radiation at different levels within the range 0-5 Gy or 0-5 Sv were identified through systematic literature searches. (bioone.org)
In some, disease rates among those exposed at different levels may have differed for reasons unrelated to radiation exposure, while many had low power to detect effects of the relevant magnitude. (bioone.org)
It results from damage to the bladder's transitional epithelium and blood vessels by toxins, pathogens, radiation, drugs, or disease. (medscape.com)
Hemorrhagic cystitis results from damage to the bladder's transitional epithelium and blood vessels by toxins, viruses, radiation, drugs (in particular, chemotherapeutic drugs), bacterial infections, or other disease processes. (medscape.com)

Since radiation-induced DNA damage is generated essentially randomly in the genome, it does not seem likely that radiation could ever be responsible for the induction of identical translocations of relevance to ALL in multiple cells of an individual and hence be the primary cause of radiation-related leukemia. (bioone.org)

Anatomy4

Organisms6

Diseases44

Chemicals and Drugs23

Analytical, Diagnostic and Therapeutic Techniques and Equipment97

Psychiatry and Psychology1

Phenomena and Processes48

Disciplines and Occupations8

Anthropology, Education, Sociology and Social Phenomena3

Technology, Industry, Agriculture6

Humanities1

Information Science13

Named Groups4

Health Care70

Geographicals16

Symptomatic radiation-induced3

Radiotherapy8

Prevalence3

Pneumonitis4

Doses of ionizing1

Effects of radiation7

Cancer51

Toxicity5

Malignancies5

Reduce the incidence1

Carcinogenesis2

Occur4

Lung injury2

Malignancy1

Squamous2

Fibrosis1

Complications2

Increases5

Chronic4

Pelvic radiation2

Severe1

Cancers2

Therapeutic2

Irradiation2

Natural incidence1

Oxidative4

Cutaneous2

Patients11

Necrosis1

Risk9

Therapy17

Oncology3

Acute radiation3

Significantly3

Complication1

Dermatitis3

Populations1

Basal1

Tissues2

Instability2

Chemotherapy1

Inflammatory1

Exposures4

Radiosurgery2

IARC3

Tumour2

Mortality2

Patient's1

Medical Radiation Physics1

Brachial2

Caused by ultraviolet1

Hormesis2

Potentially1

Postradiation1

Rate2

Tissue1

Unsafe2

Treatment6

High7

Malignant2

Mechanisms2

Disease4

Induction1