Incidence of adverse analgesia patient controlled. Medical search. Frequent questions

Opioids administered to the IT space can offer effective postoperative analgesia. (medscape.com)
The advantages of IT opioids for analgesia, especially if spinal anesthesia is already planned, include its simplicity, lack of need for catheter care or pumps, low cost, and easy supplementation with low-dose patient-controlled analgesia (PCA) opioids as needed. (medscape.com)
DILAUDID-HP INJECTION is an opioid agonist indicated for use in opioid-tolerant patients who require higher doses of opioids for the management of pain severe enough to require an opioid analgesic and for which alternate treatments are inadequate. (nih.gov)
Patients must remain on around-the-clock opioids when administering DILAUDID-HP. (nih.gov)
The analgesic regimen for lumbar laminectomy should include paracetamol and a non-steroidal anti-inflammatory drug (NSAID) or cyclooxygenase (COX)-2 selective inhibitor administered preoperatively or intraoperatively and continued post-operatively, with post-operative opioids for rescue analgesia. (springer.com)
One adverse effect of concern with opioids is the postoperative ileus (POI). (nevinmanimala.com)
Results Sixty-nine percent of patients received a combination of opioids and nonopioids. (nevinmanimala.com)
Postoperative ileus has multifactorial causes, one of which is the use of opioids for pain control. (nevinmanimala.com)
Considering the high incidence of ileus in our center and the association we found between the use of opioids and ileus, further studies should look at the doses of opioids used and whether alternative analgesic methods might result in less ileus. (nevinmanimala.com)
As a result, the Georgia-based hospital has been held as a model nationwide for patient safety using opioids. (ppahs.org)
We seek to identify the effectiveness of N 2 O as a form of procedural sedation and analgesia for children requiring painful procedures in a tertiary paediatric emergency department (ED), study the incidence of adverse events, and evaluate the safety of co-administered opioids. (annals.edu.sg)
Opioids are commonly prescribed in the peri-operative period for analgesia and pain management. (biomedcentral.com)
However, immediate adverse reactions or the long-term sequelae of chronic effects attributed to the overuse of opioids perioperatively may lead to significant morbidity and mortality [ 1 ]. (biomedcentral.com)
Despite all these severe adverse events, the intraoperative use of opioids remains a central part of anaesthesia practice. (biomedcentral.com)
1-3 Of additional concern are surgical patients who receive opioids (eg, morphine sulphate, fentanyl citrate, meperidine hydrochloride) that, according to surgical recovery guidelines, should be used minimally for pain relief. (hcplive.com)
1,3-5 Although opioids can effectively reduce pain following surgery, they are associated with adverse events (AEs), such as respiratory and/or central nervous system depression, nausea or vomiting, and pruritus. (hcplive.com)
Although existing evidence supports the use of opioid therapy for the treatment of VOC,treating physicians often encounter challenges when attempting to balance the analgesic and adverse effects of opioids. (everyonesmd.com)
A cross-sectional survey of 721 ED physicians found that emergency physicians who attend to more than one SCD patient per week were inclined to have negative attitude toward SCD patients and were less likely to redose opioids within 30 min for inadequate analgesia. (everyonesmd.com)
Commonly reported side effects of opioids are drowsiness, nausea, abdominal pain, confusion, and respiratory depression with variable incidence.Similar to other patients receiving treatment for chronic or recurrent pain, SCD patients may experience opioid-induced hyperalgesia, an enhanced pain response owing to the activation of the N-methyl-d-aspartate (NMDA) receptors. (everyonesmd.com)
COCA is excited to partner with CDC's National Center for Injury Prevention and Control to offer this call series on CDC's Guideline for Prescribing Opioids for Chronic Pain. (cdc.gov)

As members of the multidisciplinary team of clinicians involved in pain management, pharmacists can be instrumental in patient care by making clinical recommendations based on guidelines to provide safe and effective pain management, improve clinical outcomes, and diminish or prevent adverse events in pediatric patients. (uspharmacist.com)
Delay in adequate analgesia for hip fracture in geriatric patients leads to worse outcomes, including increased rate of delirium and increased hospital length of stay. (asra.com)
Effective pain control improves post-operative outcomes and patient satisfaction. (springer.com)
Post-operative pain outcomes (pain scores and analgesic requirements) were the primary focus, but other recovery outcomes-including adverse effects-were also assessed, when reported, and the limitations of the data were critically reviewed. (springer.com)
Exposing physicians to reduced residency work hours did not adversely affect patient outcomes after residency. (ahrq.gov)
No increase in short term adverse outcomes in the intervention group identified but patients were not evaluated for subtle or long-term adverse outcomes. (thoracic.org)
Primary outcome measure was the assessment of the incidence of postoperative ED. Secondary outcomes included the postoperative sedation scores and postoperative Face, Legs, Activity, Cry, and Consolability (FLACC) pain scores, time to 1st postoperative analgesic, and total postoperative analgesic consumption. (springeropen.com)
Secondary outcomes included the incidence of moderate to severe pain during rest or movement at different times within 72 hours, pain scores during rest or movement within 72 hours after surgery, analgesic use, adverse events, and indicators of postoperative recovery. (bmj.com)
in 2014, SJ/C celebrated 10 years free from opioid-related adverse outcomes under his leadership. (ppahs.org)
In order to better understand the whole body of evidence, we conducted a systematic review to evaluate the safety and efficacy of IV lidocaine for adult patients undergoing pain management in the ED through the outcomes of reduction in pain scores, need for rescue analgesia, and incidence of adverse drug reactions. (mayo.edu)
The successful applicant will use data from the Victorian Ambulance Cardiac Arrest Registry (VACAR) to study the association between resuscitation performance, defibrillation factors and paramedic debrief on patient outcomes. (monash.edu)
The secondary outcomes included postoperative adverse events, the need for rescue analgesia and the time from the end of surgery to endotracheal tube removal. (bmj.com)
The pretravel consultation and evaluation of pregnant travelers ( Box 7-01 ) should begin with a careful medical and obstetric history, specifically assessing gestational age and the presence of factors and conditions that increase risk for adverse pregnancy outcomes. (cdc.gov)
As they report in The Lancet, online December 6, Dr. Almenawer and colleagues conducted a systematic review and meta-analysis to compare patient outcomes after lumbar puncture with atraumatic needles versus conventional needles. (medscape.com)

After operation, both groups were given patient controlled intravenous analgesia for 48 h and the observation group was also administrated with intraarticular injection of ropivacaine into knee joint, while the control group with the same dosage of normal saline. (ijpsonline.com)
In order to further investigate the effect of intraarticular injection of ropivacaine into knee joint in postoperative analgesia of patellar fracture fixation, this study was conducted to compare the effect of intraarticular injection of ropivacaine into knee joint and patient controlled intravenous analgesia (PCIA) in postoperative analgesia of patellar fracture patients who were admitted in our hospital in recent years. (ijpsonline.com)
This study randomized 566 patients with acute respiratory failure or shock and hypoactive (89%) or hyperactive delirium (11%) to receive intravenous boluses of haloperidol (maximum dose, 20 mg daily), ziprasidone (maximum dose, 40 mg daily), or placebo. (thoracic.org)
For presentations of severe pain , intranasal fentanyl is a recommended first line agent as it is fast and easy to administer, avoids requiring cooperation with oral medications, and provides reliable analgesia that has been shown to be equivalent to intravenous morphine. (emergencymedicinecases.com)
Intravenous (IV) lidocaine during surgery can reduce the demand for propofol and the incidence of cardiopulmonary complications. (dovepress.com)
Standard therapy for VOC includes intravenous (IV) hydration and opioid analgesia. (everyonesmd.com)
Lidocaine for pain control, administered by intravenous (IV) injection, has been studied in various settings, including the operating room for management of perioperative pain (5) and outpatient clinics for treatment of neuropathic pain. (mayo.edu)
Although promising, the current body of evidence is limited and intravenous lidocaine for pain management needs further well-designed studies to determine its safety and efficacy before the routine use for analgesia in the ED. (mayo.edu)
Lauretti GR. Mechanisms of analgesia of intravenous lidocaine. (mayo.edu)
Developmentally normal children are generally able to sit for an intravenous (IV) catheter placement in pre-operative holding at our institution after the age of 7 years, so it is more typical to offer an IV induction for older children, though inhalational induction may still be more feasible in certain patients. (pediatricurologybook.com)
to investigate dental patients undergoing sedation using a mean dose of 0.6 mg/kg intravenous midazolam and the adverse events of sedation in patients with ID. (bvsalud.org)
This study analyzed the records of 163 dental patients with ID aged between 2 and 76 years who had undergone conscious intravenous sedation (CIV) using a mean dose of 0.61 mg/kg of midazolam at Araçatuba Dental School, São Paulo State University, Brazil. (bvsalud.org)
Intravenous sedation for dental patients with intellectual disability. (bvsalud.org)
11. Averley PA, Girdler NM, Bond S, Steen N, Steele J. A randomised controlled trial of paediatric conscious sedation for dental treatment using intravenous midazolam combined with inhaled nitrous oxide or nitrous oxide/ sevoflurane. (bvsalud.org)
Subgroup analyses of postdural-puncture headache showed no interactions between needle type and patient sex, age, position, bed rest after puncture, needle gauge, indication for lumbar puncture, use of intravenous fluid, or clinician specialty. (medscape.com)

For IT morphine, the onset of analgesia is 30-60 minutes, and the duration of analgesia is 18-24 hours, depending on the dose. (medscape.com)
[ 5 ] The incidence of nausea and vomiting for IT morphine is approximately 20% and peaks at approximately 4 hours. (medscape.com)
Morphine produces both its therapeutic and its adverse effects by interaction with one or more classes of specific opioid receptors located throughout the body. (clustermed.info)
Morphine acts as a full agonist, binding with and activating opioid receptors at sites in the peri-aqueductal and peri-ventricular grey matter, the ventromedial medulla and the spinal cord to produce analgesia. (clustermed.info)
Pharmacodynamics Plasma Level-Analgesia Relationships While plasma morphine-efficacy relationships can be demonstrated in non-tolerant individuals, they are influenced by a wide variety of factors and are not generally useful as a guide to the clinical use of morphine. (clustermed.info)
Dosages of morphine should be chosen and must be titrated on the basis of clinical evaluation of the patient and the balance between therapeutic and adverse effects. (clustermed.info)
Effects on the Central Nervous System The principal actions of therapeutic value of morphine are analgesia and sedation. (clustermed.info)
1,4 Co-administered medications include intranasal fentanyl (1.5μg/kg, maximum 100μg/dose) administered 30-60 minutes prior to enhance analgesia, 3 oral analgesics, topical anaesthesia or parenteral morphine. (annals.edu.sg)
Intrathecal morphine provides effective postoperative analgesia but is associated with adverse effects such as itching, nausea, urinary retention, sedation, ileus and life-threatening respiratory depression. (ispub.com)
This study was a parallel-group, prospective, randomized, blinded, pragmatic, controlled trial that sought to evaluate the efficacy and safety of single-dose ketamine infusion in addition to the usual care relative to those of morphine, for the management of sickle VOC. (everyonesmd.com)
Four of six randomized controlled trials found comparable or superior reduction in pain scores using IV lidocaine when compared to active controls (ie: morphine). (mayo.edu)
The treatment is initiated by titration with an immediate-release morphine formulation (tablets or solution) to a morphine dose which gives adequate pain control. (who.int)
In patients with severe pain the usual initial dose is 10-30 mg morphine hydrochloride at 12- hour intervals. (who.int)
Usual y, Vendal retard 200 mg prolonged-release tablets are intended for the relief of particularly cancer pain in patients who tolerate morphine and require a daily morphine dose of more than 200 mg. (who.int)
Patients receiving Vendal retard prolonged-release tablets in place of parenteral morphine should be treated cautiously, based on individually different sensitivity. (who.int)

and follow patients for signs and symptoms of respiratory depression and sedation. (nih.gov)
BACKGROUND: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) has been used in patients with COVID-19 acute respiratory distress syndrome (ARDS). (deliriumnetwork.org)
If a decision is made to treat serious respiratory depression in the physically dependent patient, administration of the antagonist should be initiated with care and by titration with smaller than usual doses of the antagonist. (pfizermedicalinformation.com)
A prospective two center study of patients with respiratory failure or shock found that at 3 months 40% of patients had deficits in cognition similar to those seen in moderate traumatic brain injury, and 26% had deficits similar to mild Alzheimer's disease. (thoracic.org)
At SJ/C, respiratory therapists (RTs) walk the patient floor once a shift to see patients. (ppahs.org)
RTs also conduct assessments of crucial patient vitals: respiratory rate, respiratory effort, SpO2, and end tidal CO2. (ppahs.org)
The key is that we have a respiratory therapist that will go and monitor the patient, look at their trends, and set their alarms based on what's happened with the patient at the bedside. (ppahs.org)
Propofol-based sedation has been widely used for gastroscopy, but the risk of respiratory suppression in elderly patients should not be overlooked. (dovepress.com)
Sections on the prevention of bacterial pneumonia in mechanically ventilated and/or critically ill patients, care of respiratory-therapy devices, prevention of cross-contamination, and prevention of viral lower respiratory tract infections (e.g., respiratory syncytial virus {RSV} and influenza infections) have been expanded and updated. (cdc.gov)
Traditional preventive measures for nosocomial pneumonia include decreasing aspiration by the patient, preventing cross-contamination or colonization via hands of personnel, appropriate disinfection or sterilization of respiratory-therapy devices, use of available vaccines to protect against particular infections, and education of hospital staff and patients. (cdc.gov)

8 The authors also indicated that the incidence of unreported pain remains unknown, but this may be the result of various patient and/or parent/caregiver factors, including a lack of awareness about pain-management strategies, apprehension regarding unnecessary medications and adverse effects (AEs), and fear of injectable analgesics. (uspharmacist.com)
Multiple barriers to effective pain management in the pediatric patient population, especially in the hospital setting, have been documented in the literature, including difficulty evaluating pain in pediatric patients, inadequate or insufficient prescriber medication orders to meet the needs of pediatric patients, lack of time to administer analgesics before procedures, unawareness and/or underreporting of pain by parents/caregivers, and lack of knowledge about pain management for pediatric patients. (uspharmacist.com)
Objective In this study, we looked at the severity of postoperative pain, the type of analgesics used to control the pain, and the incidence of POI at Baghdad Teaching Hospital. (nevinmanimala.com)
A structured questionnaire was employed focusing on types of analgesics, degree of pain control, and the presence of ileus. (nevinmanimala.com)
Sedative analgesics such as remifentanil and dexmedetomidine have been demonstrated in studies to improve the impact of local nerve block and extend the duration of analgesia and have therefore become important adjuvants during surgical anesthesia. (hindawi.com)
The opioid based analgesics and land mark techniques have undesirable consequences, regional analgesia technique with ultrasound requires resource and expertise while different wound infiltration techniques are new techniques with minimal side effect and easy to administer. (researchsquare.com)

Time to onset of analgesia at the dorsum of foot, maximum level of sensory block and the time required to achieve it were noted. (ispub.com)

This can be beneficial to a variety of patient populations, including those at risk for cognitive dysfunction after general anesthesia. (medscape.com)
The aim of this study was to compare the effect of dexmedetomidine versus ketamine when added to caudal bupivacaine on the incidence of emergence delerium (ED), postoperative sedation, and analgesia in pediatric patients undergoing inguinal hernia repair under sevoflurane anesthesia. (springeropen.com)
Eighty seven pediatric patients who underwent elective inguinal hernia repair under sevoflurane anesthesia were randomly distributed into one of three equal groups. (springeropen.com)
Both dexmedetomidine (1 μg/kg) and ketamine (0.5 mg/kg) added to pediatric caudal block were effective to control pediatric ED after sevoflurane anesthesia. (springeropen.com)
2017 ). However, emergence delirium (ED) in pediatrics after sevoflurane anesthesia is common, with a reported incidence up to 80% (Cravero et al. (springeropen.com)
The conventional dose of remifentanil combined with dexmedetomidine anesthesia has a good anesthetic effect in clinical applications, but at the same time, drug-related side effects are strong, and even excessive sedation of patients occurs, which is not conducive to patient safety [ 4 ]. (hindawi.com)
In comparison to general anesthesia, brachial plexus block is easier to administer, requires less anesthetic medication, has a minimal effect on the entire body, maintains stable circulation, and provides prolonged postoperative analgesia compared to local infiltration anesthesia, and the analgesic effect and intraoperative treatment are superior. (hindawi.com)
Methods A total of 126 adult patients undergoing partial hepatectomy under general anesthesia were randomly assigned to receive intrathecal hydromorphone (100 μg) or no block. (bmj.com)
Zynrelef is contraindicated for use in patients undergoing obstetrical paracervical block anesthesia or coronary artery bypass graft (CABG) surgery, as well as among patients with a history of asthma, urticaria, other allergic-type reactions after taking aspirin or other NSAIDs or in those with hypersensitivity to any local anesthetic agent of the amide-type. (empr.com)
In this prospective, randomized, double- blind study, we investigated the postoperative analgesic efficacy of intrathecal midazolam 2.5mg as an adjunct to bupivacaine for spinal anesthesia in 80 patients undergoing lower limb orthopedic surgery. (ispub.com)
Spinal anesthesia with bupivacaine is administered routinely for lower limb surgery 1 and provides effective analgesia in the early postoperative period. (ispub.com)
Patients were excluded from the study if there was a contraindication to regional anesthesia, known sensitivity to study drugs, or were on chronic analgesic therapy. (ispub.com)
The level of analgesia was recorded continuously using the proprietary index IOC2 (Index of consciousness 2,namely qNOX) (Angel-6000D Multi-parameter Anesthesia Monitor, Shenzhen Weihaokang Medical Technology Co., Ltd, Guangdong, China). (researchgate.net)
Avoids common adverse effects of general anesthesia: Such adverse effects include nausea, sore throat, alteration of mental status, and cognitive dysfunction. (medscape.com)
Anesthesia plans may vary to include anesthesia for same-day outpatient surgery procedures in healthy patients with an isolated urologic concern or they may be more involved and complex. (pediatricurologybook.com)
Anesthesia in medically complex patients or those involving multiple stages of surgical intervention may include multimodal analgesia, various neuraxial or regional anesthetic block techniques in addition to general anesthesia and may require inpatient stays where postoperative acute pain services can be provided. (pediatricurologybook.com)
Medically complex patients may benefit from a visit to the pre-anesthesia or pre-surgical optimization clinic to ensure that all follow-up information is up to date (e.g., echocardiogram and cardiology clearance in patients with congenital heart disease) and to allow for timely completion of any necessary laboratory work or imaging. (pediatricurologybook.com)
Emerging studies have shown that increased intensity and duration of acute pain may be correlated with a higher incidence of chronic pain, and regional anesthesia, ketamine, gabapentinoids, and cyclooxygenase (COX) inhibitors may be helpful for prevention of chronic postsurgical pain. (mhmedical.com)
Overnight fasting reduces the risk for aspiration of stomach contents when the patient is placed under general anesthesia . (medscape.com)
Therefore, patients can be given their routine medications with sips of water up to 2 hours before anesthesia. (medscape.com)
Conscious sedation has become established as an important alternative to general anesthesia (GA) in dental treatment of patients with intellectual disability (ID). (bvsalud.org)

Patients received caudal dexmedetomidine had longer time to 1st postoperative analgesia and less postoperative analgesic consumption but longer postoperative sedation when compared with ketamine with no significant difference between both drugs as regards the incidence of perioperative adverse events. (springeropen.com)

The safety of epidural analgesia for open hepatectomywill epidural hematoma occur? (thaiscience.info)

Two further papers about wrist injury in this edition of the print journal address safe and effective analgesia during manipulation of distal fractures. (bmj.com)

Multimodal analgesia has frequently been recommended for enhanced recovery after surgery [ 5 ]. (springer.com)
Selective COX-2 inhibitors may be a better choice for multimodal analgesia than conventional non-selective NSAID. (medscape.com)

however, according to the Emergency Medicine Residents' Association, among pediatric patients, pain accounts for an estimated 78% of emergency department (ED) visits, including episodic, acute, or exacerbations of chronic pain. (uspharmacist.com)
How Many Acute Pain Services Are There in the United States, and Who Is Managing Patient-controlled Analgesia? (asahq.org)
[ 23 ] Therefore, we suggest that 400 mg of celecoxib is more optimal than 200 mg in controlling acute postoperative pain. (medscape.com)
In acute pain conditions (soft tissue trauma, strains, and sprains) placebo controlled trials had a relative benefit of 1.7 (1.5 to 1.9), the number needed to treat was 3.9 (3.4 to 4.4). (bmj.com)
40 treated patients) exaggerated effectiveness of topical non-steroidals by 33% in acute conditions but not in chronic conditions. (bmj.com)
In both acute and chronic pain local and systemic adverse events and withdrawal from the study related to the drug had a low incidence and were no different from placebo. (bmj.com)
Consecutive patients with acute wounds aged 18 and over were recruited and questioned about their tetanus immunisation status. (bmj.com)
The incidence of postoperative acute as well as chronic pain is very high which has a tremendous impact on the mother, family, healthcare providers, and healthcare delivery. (researchsquare.com)
Inadequately treated acute pain can develop into chronic pain in some patients. (mhmedical.com)

The Food and Drug Administration (FDA) has approved Zynrelef™ (bupivacaine and meloxicam) extended-release solution for use in adults for soft tissue or periarticular instillation to produce postsurgical analgesia for up to 72 hours in adults after bunionectomy, open inguinal herniorrhaphy and total knee arthroplasty. (empr.com)

Randomised controlled trials (RCTs) published in the English language from 1 January 2008 until 31 March 2020-assessing post-operative pain using analgesic, anaesthetic and surgical interventions-were identified from MEDLINE, EMBASE and Cochrane Databases. (springer.com)
A major limitation of the extant reviews is the lack of rigorous investigation of clinical characteristics that would maximize the benefit harms ratio in favor of surgical patients. (biomedcentral.com)
We will focus on the identification of surgical models and patient characteristics that have shown benefit and adverse effects from pregabalin. (biomedcentral.com)
Reducing the incidence of retained surgical instrument fragments. (ahrq.gov)
More than 73 million patients undergo surgical procedures each year in the United States. (hcplive.com)
Pediatric urology procedures cover a wide range of patient types, surgical approaches, and a broad spectrum of anesthetic requirements and approaches. (pediatricurologybook.com)
Data from the US and Europe have shown that up to 54% of patients will exhibit general anxiety, nightmares, nighttime crying, enuresis, separation anxiety, and temper tantrums for 2 weeks after their surgical procedure. (pediatricurologybook.com)
Kluger et al showed that 44% of surgical patients took medications prior to surgery, with an average of 2.1 drugs per patient. (medscape.com)

METHODS: Incidence and severity of dysphagia was evaluated preoperatively and for time of three years after ACDF (regular outpatient check-ups) â prospective study with 3-years follow-up. (bvsalud.org)
METHODS: We retrospectively reviewed adult patients on VV-ECMO for severe COVID-19 ARDS in the Johns Hopkins Hospital ECMO registry in 2020-2021. (deliriumnetwork.org)
This thematic review focused on methods to improve safety for chemotherapy patients and found evidence that computerized provider order entry could reduce medication errors. (ahrq.gov)
Methods This observational study was conducted among 100 patients who were residents at the general surgery wards of Baghdad Teaching Hospital. (nevinmanimala.com)
Patients suspected of cirrhosis in these scoring systems might be confirmed without liver biopsy by imaging based non-invasive methods such as ultrasonography based elastography such as transient elastography and two-dimensional shear wave elastography, and magnetic resonance elastography. (e-cmh.org)
Filtering out chronic hepatitis B patients with advanced fibrosis or cirrhosis is very important to determine the antiviral therapy or evaluate prognosis because current guidelines generally recommend antiviral therapy in patients with cirrhosis regardless of alanine transaminase levels [ 8 - 10 ], and thus, non-invasive test methods can be very beneficial in determining antiviral therapy without a liver biopsy. (e-cmh.org)
Methods: The study was approved by the local ethics committee, including data from 60 patients scheduled for ambulatory surgery undergoing general anaesthesia with propofol and remifentanil, using TCI. (researchgate.net)
Several methods are available to help decrease patients' preoperative anxiety and improve their perioperative experience. (pediatricurologybook.com)
Methods We searched PubMed, Embase (Ovid), Cochrane Central Register of Controlled Trials, Wanfang databases and China National Knowledge Infrastructure from their inception to 31 September 2022 for randomised comparative clinical trials that compared single-injection SAPB with systemic analgesia or different forms of regional analgesia in children. (bmj.com)
Review patient evaluation methods that can be used to identify the most appropriate treatment options for chronic pain. (cdc.gov)

The main disadvantages of this technique are limited duration of action (in comparison to catheter-based techniques) and the adverse effects discussed above. (medscape.com)
Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals. (nih.gov)
Age of patients, duration of surgery and pre-existing dysphagia correlated positively very weakly to weakly with severity of dysphagia after ACDF. (bvsalud.org)
Because the duration of opioid reversal is expected to be less than the duration of action of hydromorphone in Hydromorphone Hydrochloride Injection, carefully monitor the patient until spontaneous respiration is reliably reestablished. (pfizermedicalinformation.com)
RCT found daily interruption of sedation in a MICU population resulted in shorter duration of mechanical ventilation and ICU stay, less total dose of sedation, and less use of diagnostic tests to work-up impaired mental status compared to the control group. (thoracic.org)

It seems that the incidence of opioid-related adverse events is generally underestimated in the clinic, as previous research has reported that opioid-related adverse events may occur in 12% of surgeries [ 2 ]. (biomedcentral.com)

And statistical analysis was conducted on adverse reactions of the two groups. (ijpsonline.com)
The application of intraarticular injection of ropivacaine into knee joint can effectively relieve the pain patients suffer after patellar fracture fixation and alleviate local inflammatory response without significant adverse reactions. (ijpsonline.com)
The most common adverse reactions reported with Zynrelef (incidence 10% or greater) included constipation, vomiting, and headache. (empr.com)
Gastroscopy is one of the most important tools for diagnosing upper gastrointestinal diseases, but nausea, vomiting, and other adverse reactions during the examination make it difficult for many patients to cooperate effectively, especially for the elderly who are more prone to dangerous events. (dovepress.com)
The evidence for safety of IV lidocaine in the ED is also limited, with only 6 studies reporting the adverse drug reactions. (mayo.edu)
0.05) between absence and presence of adverse reactions. (bvsalud.org)
Adverse reactions were observed in 21.47% of the cases. (bvsalud.org)

The aim of this study was to investigate whether the application of OFA by using esketamine in intraoperative analgesia could minimize the side effects of postoperative nausea and vomiting (PONV), as well as other short-term side effects related to anaesthesia. (biomedcentral.com)
The incidence of postoperative nausea and vomiting was comparable between SAPB and controls. (bmj.com)

For opioid-naïve and opioid non-tolerant patients, the initial dose of Vantrela ER is 15 mg tablets orally every 12 hours. (rxlist.com)
For patient controlled analgesia (PCA), recommended demand dose is 0.35 mg, with a 6-minute lock-out. (nih.gov)
The effective dose in opioid-tolerant patients may be 10 to 50 times as great (or greater) than the appropriate dose for opioid-naïve individuals. (clustermed.info)
The optimum dose of intrathecal midazolam for postoperative analgesia is not identified. (ispub.com)
We examined whether IV lidocaine reduces the dose of propofol and the occurrence of adverse events during gastroscopy in elderly patients. (dovepress.com)
EXPAREL, the only single-dose, long-acting analgesic that offers a nonopioid option for postsurgical pain control, can play an important role in a multimodal approach. (hcplive.com)
Thereafter, the patient is transferred to the same daily dose of Vendal retard prolonged-release tablets. (who.int)
Patients with low body weight (less than 70 kg) require a lower starting dose. (who.int)
Caution should be exercised and the initial dose should be reduced in elderly patients and patients with impaired hepatic or renal function. (who.int)
The correct dose for every patient is a dose that is sufficient to control pain with no or tolerable side effects for 12 hours. (who.int)
The results indicate that, acting by itself, a tenfold reduction in dose from a 5% effect level is associated with effect incidences ranging from slightly less than one in ten thousand, for a median chemical/response, to a few per thousand, for chemicals and responses that have greater human interindivid- ual variability than 19 out of 20 typical chemicals/responses. (cdc.gov)

Over 100 free commonly used clinical formulas and calculator tools to help diagnose, treat, prevent, and determine prognosis of patients at point of care. (guidelinecentral.com)
Identify clinical preventive services that are appropriate for your patients. (guidelinecentral.com)
To ascertain the clinical utility and sustained benefits of the commonly used 80% pain reduction threshold following two comparative medial branch blocks prior to RFA, researchers conducted a telephone survey study of 85 patients from one institution. (asra.com)
The recommendations are based on procedure-specific evidence as well as the balance between the efficacy and adverse effects of analgesic techniques and clinical relevance [ 8 , 9 ]. (springer.com)
Clinical information transfer and medication reconciliation in patients transferred from the pediatric intensive care unit. (ahrq.gov)
Regional caudal blocks have been shown to reduce the incidence of sevoflurane-induced ED in clinical studies in children (Aouad et al. (springeropen.com)
Most patients in clinical trials were treated with doses of 16 mg/hour or less. (wikipedia.org)
In clinical studies, no significant changes occurred in serum triglyceride levels in the Cleviprex treated patients. (wikipedia.org)
In clinical trials, the safety profile of clevidipine was generally similar to sodium nitroprusside, nitroglycerin, or nicardipine in patients undergoing cardiac surgery. (wikipedia.org)
Nirav Patel and colleagues from the South East of England have undertaken a randomised controlled trial to investigate the cost and clinical effectiveness of immediate MR scanning in this patient group. (bmj.com)
A systematic review of the performance characteristics of clinical event monitor signals used to detect adverse drug events in the hospital setting. (ahrq.gov)
Clinical handover of patients arriving by ambulance to the emergency department: a literature review. (ahrq.gov)
2 Other adjuvants such as clonidine and ketamine have also been administered but none have become established in regular clinical use because of their adverse effects. (ispub.com)
Health-Related Quality of Life in Patients with Inflammatory Bowel Disease in Clinical Remission: What Should We Look For? (mdpi.com)
This should change clinical practice and result in fewer patients with lumbar puncture complications. (medscape.com)
Neuropathic pain (NP) originates as a In non-oncological patients, chronic NP is The authors declare there are direct consequence of a lesion or disease common in clinical practice and consider- no conflict of interests. (bvsalud.org)

A recent publication in Practical Pain Management indicated that an estimated 33% to 82% of hospitalized pediatric patients experience moderate-to-severe pain, especially post surgery, and an estimated 20% of those patients do not obtain adequate pain relief, which may result in chronic pain. (uspharmacist.com)
The results of this study showed that CIV is a useful method for dental treatment of patients with ID and these patients can need higher doses of sedative to reach an adequate level of sedation. (bvsalud.org)

Postoperatively, the patient experienced a rare complication of anchoring blade-related adjacent vertebral fracture leading to construct failure and recurrence of myelopathic symptoms, necessitating revision surgery. (bvsalud.org)
To explore the impact of intraarticular injection of ropivacaine into knee joint on the postoperative analgesia and local inflammatory response after patellar fracture fixation is the main objective. (ijpsonline.com)
The subjects of this study are 136 patients with patellar fracture who received selective open reduction Kirschner wire tension band fixation of patellar fracture in our hospital from March 2018 to November 2020 were divided into two groups on the basis of random number table, each with 68 cases. (ijpsonline.com)
The incidence of patellar fracture is about 0.7 %-1 % of systemic fractures, with a tendency to increase in recent years [ 1 , 2 ]. (ijpsonline.com)
We examined provider ordering patterns before and after implementation of opioid use guidelines for ED patients overall and the specific subsets of ED patients with either chronic opioid use or fracture. (medecinedurgence.fr)
The immediate reduction in parenteral opioid use was significantly larger in the cohort of patients with chronic pain (OR = 0.81, 95% CI = 0.72-0.91), whereas the fracture cohort showed no change (OR = 1.10, 95% CI = 0.97-1.25). (medecinedurgence.fr)

[ 1 ] The use of regional anesthetic and analgesic techniques can offer superior overall pain control and reduced postoperative opioid requirements. (medscape.com)
Various regional analgesia techniques exist that can be used to promote postoperative pain relief. (medscape.com)
The dosing of Vantrela ER is individualized based on the severity of pain, patient response, prior analgesic experience, and risk factors for addiction, abuse, and misuse. (rxlist.com)
Research has indicated that pain management in the pediatric patient population often presents clinicians with various challenges. (uspharmacist.com)
Moreover, it is not always adequately assessed and treated, and this may result in long-term and short-term adverse effects, including exacerbation of pain, anxiety, and fear. (uspharmacist.com)
however, various studies have indicated that pain is often underestimated and not adequately managed among the pediatric patient population. (uspharmacist.com)
2-4 According to the World Health Organization (WHO) Guidelines on the Management of Chronic Pain in Children, the management of pain in pediatric patients can be challenging and multifaceted, and there is a lack of high-quality research studies with regard to optimal treatment interventions and management approaches in this patient population. (uspharmacist.com)
5 Pain management entails a patient-centered approach involving pharmacologic and nonpharmacologic measures tailored to patient needs. (uspharmacist.com)
however, it may be challenging to assess and manage pain in pediatric patients-especially in very young patients-since they are unable to verbalize/articulate their pain. (uspharmacist.com)
6 The IASP indicates that, globally, chronic pain affects approximately 20% to 35% of pediatric patients. (uspharmacist.com)
6 Pain in pediatric patients also occurs in those who have undergone surgery, those with neuropathic pain, and those with chronic conditions such as sickle cell disease (SCD), cancer, juvenile arthritis, fibromyalgia, and inflammatory bowel disease. (uspharmacist.com)
4 Unmanaged pain can affect patient productivity, academic performance, day-to-day activities and social activities with others, and it may cause sleep disturbances, depending upon age. (uspharmacist.com)
Although patients with lumbar disc herniation (LDH) can achieve significant relief from lower back and leg pain after lumbar microdiscectomy, a few patients complain of discomfort due to residual leg numbness (RLN). (bvsalud.org)
A total of 38 patients at a tertiary-care institution with chronic abdominal pain from chronic pancreatitis (17 with VAPS and 21 with AMPS) underwent bilateral subcostal transversus abdominis plane (STAP) blocks with depot methylprednisolone 80 mg. (asra.com)
95% (20/21) of patients with AMPS who underwent bilateral STAP had clinically significant pain relief at 3 months, and 62% (13/21) of patients had durable relief. (asra.com)
The remaining one patient reported transient pain relief (2 weeks) after STAP and proceeded to have ultrasound-guided trigger point injections, which provided clinically significant relief at 3 months. (asra.com)
Outcome measurements included Numerical Rating Scale (NRS), Patient Global Impression of Change (PGIC), and report of 50% or more reduction of index pain. (asra.com)
Patients who had undergone lumbar medial branch RFA after 80% relief from two comparative medial branch blocks showed substantial pain relief. (asra.com)
Lumbar laminectomy is commonly performed in patients with lumbar spinal stenosis to relieve low back pain, reduce radiculopathy and improve overall function. (springer.com)
How can we enhance perioperative pain management in patients undergoing lumbar laminectomy? (springer.com)
Inclusion criteria were randomised control trials (RCTs) or systematic reviews of analgesic, anaesthetic and operative interventions, published in the English language assessing pain management for patients undergoing up to two-level lumbar laminectomy. (springer.com)
Are Nonpharmacologic Pain Interventions Effective at Reducing Pain in Adult Patients Visiting the Emergency Department? (medecinedurgence.fr)
We performed a qualitative summary of all studies meeting inclusion criteria and meta-analysis of randomized controlled studies measuring postintervention changes in pain. (medecinedurgence.fr)
Of these, 23 studies reported significantly reduced pain compared to control, 24 studies showed no difference, and nine studies had no control group. (medecinedurgence.fr)
Meta-analysis included 22 qualifying randomized controlled trials and had a global standardized mean difference of -0.46 (95% confidence interval = -0.66 to -0.27) in favor of nonpharmacologic interventions for reducing pain. (medecinedurgence.fr)
Despite many study efforts and optimization of postoperative pain treatment over the last 30 years, a significant reduction in the incidence of phantom limb pain has not been achieved. (nih.gov)
Current studies have also shown that at least 50% of patients develop phantom pain after 6 months. (nih.gov)
Perioperative coxibs have been shown to reduce postoperative pain and analgesic consumption while enhancing patient satisfaction. (medscape.com)
The primary outcome was the incidence of moderate to severe pain during movement at 24 hours after surgery. (bmj.com)
Discussion Intrathecal hydromorphone 100 μg reduced the incidence of moderate to severe pain and pain scores during movement within 24 hours after partial hepatectomy. (bmj.com)
Measures of treatment success approximating at least 50% reduction in pain, local and systemic adverse effects. (bmj.com)
We sought reports of randomised controlled trials of topical non-steroidal anti-inflammatory drugs in which pain was an outcome and included those that compared topical non-steroidal anti-inflammatory drug(s) with placebo, with another topical non-steroidal, or with an oral non-steroidal. (bmj.com)
Other investigators have suggested that the anxiolytic, sedative and sleep restorative properties of these drugs may additionally benefit patients with pain. (biomedcentral.com)
Among patients undergoing unilateral simple bunionectomy (N=412), treatment with Zynrelef was associated with a significant reduction in pain intensity compared with either bupivacaine HCl or saline placebo for up to 72 hours. (empr.com)
Zynrelef also showed a significant reduction in pain intensity vs saline placebo for the first 48-hour and 72-hour postoperative periods in patient who underwent primary unilateral total knee arthroplasty (N=222). (empr.com)
Your initial approach to pain control when the patient hits the ED door will depend on severity of pain. (emergencymedicinecases.com)
For mild to moderate pain , consider oral agents such as ibuprofen, which has been shown to be more effective than acetominophen for pain control in orthopedic injuries in children. (emergencymedicinecases.com)
This resource provides evidence-based recommendations for a variety of applications of intranasal medication including pain control, sedation and seizure management. (emergencymedicinecases.com)
SJ/C found that in the case of high-risk patients, such as sickle cell patients using a PCA, this enabled for better pain management because staff felt more comfortable administering correct dosages. (ppahs.org)
Visual analogue scale (VAS-consisting of 100 mm line with 0 = no pain and 100 = worst possible pain) was explained to all patients during the preoperative visit. (ispub.com)
TruProfen Flavored Tab is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs. (drugs.com)
IV lidocaine can significantly reduce the amount of propofol, the incidence of hypoxia and postoperative pain during gastroscopy in elderly patients, with a higher patient and gastroscopist satisfaction. (dovepress.com)
The majority experience suboptimal pain management following surgery, and, particularly for patients who receive a major procedure (eg, colorectal surgery), the pain can be severe, heighten the stress response, and compromise the restoration of function. (hcplive.com)
Improves pain control: Regional techniques can block or reduce pain anywhere from several hours to several days, depending on the technique used. (medscape.com)
Greater pain control has the potential to allow for earlier hospital discharge and may improve the patient's ability to tolerate physical therapy. (medscape.com)
Its use in the Emergency Department (ED), however, has only recently gained attention after emerging evidence for the management of pain of renal colic patients in the ED (6,7). (mayo.edu)
The current public health crisis of opioid addiction driven by increased prescribing of these medications, and increased number of overdose-related deaths, further emphasizes the need for alternative approaches for pain control. (mayo.edu)
At times, treating the underlying cause of the pain (eg, dental caries) may be all that is needed, and pharmacologic therapies may not be required for additional analgesia. (mhmedical.com)
For excellent patient education resources, see eMedicineHealth's patient education article Pain After Surgery . (medscape.com)
And describe the role of patient beliefs and expectations and value of exercise, education, and non-opioid drug treatments and the management of muscular skeletal pain complaints. (cdc.gov)
Neuropathic pain affects 2 % of the population and 15 out of 100 patients who go to a physician suffer from neuropathic pain. (bvsalud.org)
This type of pain is common in cancer patients. (bvsalud.org)
pain relief in palliative care patients, a case series. (bvsalud.org)

RESULTS: Our study included 133 patients who underwent one-, two- or three-level ACDF with zero-profile spacer in years 2013â 2018. (bvsalud.org)
We prospectively collected and analyzed patients with LDH who underwent microdiscectomy between September 2016 and December 2020. (bvsalud.org)
Of the 17 patients with VAPS who underwent STAP blocks, 100% failed treatment (17/17). (asra.com)
A retrospective analysis was performed on all patients less than 18 years who underwent procedural sedation with N 2 O as a primary agent from 1 April 2013 to 31 September 2021, at the ED of KK Women's and Children's Hospital, Singapore. (annals.edu.sg)
Caesarean section was performed on 39% of patients who underwent the procedure compared to 61% of the control group. (who.int)

Several investigators have compared different anesthetic techniques to assess their influence on incidence and severity of emergence delirium. (springeropen.com)

Assessment of adverse events in medical care: lack of consistency between experienced teams using the Global Trigger Tool. (ahrq.gov)
Adverse events associated with home blood transfusion: a retrospective cohort study. (ahrq.gov)
As well as this they studied the patient record to see whether the observations had led to escalation events. (bmj.com)
We publish articles in pharmaceutical sciences and related disciplines (including biotechnology, cell and molecular biology, drug utilization including adverse drug events, medical and other life sciences, and related engineering fields). (ajol.info)
For SJ/C, the first pilot program in 2004 to reduce adverse events stemmed from several patient incidences. (ppahs.org)
Risk factors for adverse drug events: a 10-year analysis. (ahrq.gov)
All sedation-related adverse events and interventions were prospectively documented in the sedation forms in the medical records and extracted into the database. (annals.edu.sg)
Univariate regression analyses were performed to identify predictors of adverse events. (annals.edu.sg)
Sixteen (1.7%) patients had sedation-related adverse events, of whom 2 received IM ketamine subsequently, and 14 (1.5%) received N 2 O only (Table 1). (annals.edu.sg)
This trial may show that the synergy of esketamine and propofol anaesthesia reduces PONV as well as other short-term adverse events, thereby providing a better safety and satisfaction profile of ERAS for laparoscopic appendectomy and cholecystectomy. (biomedcentral.com)
20 adverse events reported across the studies, being 19 non-serious and 1 serious. (mayo.edu)

We conducted a randomized controlled trial to examine whether adding intrathecal hydromorphone to a multimodal strategy could safely improve analgesic efficacy for patients undergoing partial hepatectomy. (bmj.com)
We conclude that intrathecal midazolam 2.5mg provided moderate prolongation of postoperative analgesia when used as an adjunct to bupivacaine. (ispub.com)
10 In this prospective, randomized, double-blind study, we evaluated the analgesic efficacy of a combination of intrathecal midazolam and bupivacaine and compared it with bupivacaine alone in patients undergoing lower limb orthopedic surgery. (ispub.com)
The patients were immediately placed in the supine position after intrathecal administration of the study drugs. (ispub.com)
Intrathecal (IT) narcotics can offer effective postoperative analgesia. (medscape.com)

It also underscores the need for a high index of suspicion for potential hardware-related complications in patients presenting with recurring symptoms post-ACDF, contributing to the understanding of such rare complications. (bvsalud.org)
Also, the incidence of perioperative complications were assessed. (springeropen.com)
There was no intergroup significant difference as regards the incidence of perioperative complications. (springeropen.com)
It is helpful to know when the patient had their last meal but there is not a lot of research that supports mandatory fasting to prevent complications of aspiration in procedural sedation. (emergencymedicinecases.com)

Various adjuvants have been added to spinal local anesthetic to prolong postoperative analgesia. (ispub.com)

After approval by the hospital ethics committee and obtaining written informed consent, 80 patients (ASA class I and II), aged 20 to 50 years, scheduled to undergo elective lower limb orthopedic surgery (internal fixation of femur) were included in this prospective, randomized, double-blind trial. (ispub.com)

A systematic review of the literature associated with analgesia after lumbar laminectomy was conducted in accordance with the PROSPECT methodology [ 9 ]. (springer.com)
Quantitive systematic review of randomised controlled trials. (bmj.com)

Lidocaine appeared to be effective in patients with renal colic and critical limb ischemia, and did not appear to be beneficial for migraine headaches. (mayo.edu)
Most studies did not describe in detail which agent or doses were used after the use of IV lidocaine and controls. (mayo.edu)

Postdural-puncture headache incidence dropped significantly from 11.0% in the conventional needle group to 4.2% in the atraumatic group. (medscape.com)

Nine hundred patients (98%) had their procedures successfully completed using N 2 O sedation, with or without pre-planned oral, intranasal or topical analgesia. (annals.edu.sg)
10. Fukuta O, Braham RL, Yanase H, Kurosu K. The sedative effects of intranasal midazolam administration in the dental treatment of patients with mental disabilities. (bvsalud.org)

[ 6 ] The incidence of urinary retention is unclear because many patients receive preemptive urinary catheterization, but it is estimated to occur in 10-40% of patients. (medscape.com)

[ 3 ] but the incidence is probably lower now because smaller doses are currently used. (medscape.com)

Nitrous oxide (N 2 O) produces dissociative euphoria, amnesia and analgesia, and is a common sedative for procedural sedation in paediatric emergency departments (EDs) due to its non-parenteral administration and good safety profile. (annals.edu.sg)

Of the remaining 18 patients, six (0.7%) received Bier's block (2 for inadequate sedation, 2 given prior to N 2 O sedation and 2 given concurrently). (annals.edu.sg)

Efforts to reduce opioid consumption and their associated adverse effects have been recently promoted [ 7 ]. (springer.com)
Standard drug concentrations and smart-pump technology reduce continuous-medication-infusion errors in pediatric patients. (ahrq.gov)
Enhanced Recovery after Surgery ® (ERAS ® ) protocols involve patient-centered, multidisciplinary care to help reduce the stress response following surgery and to optimize recovery. (hcplive.com)
Heightened awareness and diligent documentation of patient medications from admission to discharge can reduce serious problems in the perioperative management of society's increasingly elderly and frail population. (medscape.com)

[ 16 ] The analgesic effects of aspirin may confuse the benefits of celecoxib, even though both groups are allowed to have aspirin in our study, and use of aspirin does not prevent the thromboembolic adverse effects of coxibs. (medscape.com)
Some drugs (eg, beta-blockers) have potential adverse effects when discontinued abruptly and should be given parenterally in the perioperative period. (medscape.com)
This paper discusses the current results of analyzing these data to derive estimates for distributions of human susceptibility to different routes of exposure and types of adverse effects. (cdc.gov)

and in patients with severe aortic stenosis. (wikipedia.org)
However, the degree of liver stiffness from transient elastography can be overestimated in case of severe inflammation of liver [ 13 ], and the measurement of fibrosis may be difficult in patients with obesity or ascites. (e-cmh.org)

The aim of this study was to identify risk factors for incidence and severity of dysphagia after ACDF with zero-profile spacer. (bvsalud.org)
Influence of selected factors on the incidence and severity of postoperative dysphagia was evaluated. (bvsalud.org)
Myelopathy and GERD had significant impact on incidence and severity of pre-existing dysphagia. (bvsalud.org)
CONCLUSION: Risk factors for incidence and severity of pre-existing dysphagia were myelopathy and GERD. (bvsalud.org)

0.05), than the control group did at identical time points. (ijpsonline.com)

Healthcare workers' experiences of patient safety in the intensive care unit during the COVID-19 pandemic: a multicentre qualitative study. (ahrq.gov)
Qualitative study about the experiences of colleagues of health professionals involved in an adverse event. (ahrq.gov)
Jane McVicar from Liverpool, UK has carried out a fascinating study that compares (patient recalled) immunisation history and immediate point of care testing in establishing the anti-tetanus status of patients with wounds. (bmj.com)
Similar results were observed in a study involving 418 patients undergoing unilateral open inguinal herniorrhaphy. (empr.com)
This study also included a group of patients treated with Zynrelef plus ropivacaine, as well as those who received bupivacaine only. (empr.com)
Encouraging resident adverse event reporting: a qualitative study of suggestions from the front lines. (ahrq.gov)
Our previous study found that predictive qNOX detects hypothermia and has a potentiating effect on the depth of analgesia [9]. (researchgate.net)
Sixteen patients (ten with one or more intestinal fistula) developed abdominal wall dehiscence were included in this study. (who.int)

Centers for Disease Control and Prevention. (cdc.gov)
I'm Dr. Loretta Jackson-Brown and I'm representing the Clinician Outreach and Communication Activity, COCA in the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
Dr. Tauben and Dr. Robinson would like to disclose that their employer, the University of Washington, received a contract payment from the Centers for Disease Control and Prevention. (cdc.gov)
Dr. Dowell is Senior Medical Advisor for the Division of Unintentional Injury Prevention and Control at the Centers for Disease Control and Prevention. (cdc.gov)

Patients of group B received caudal injectate of 1 ml/kg bupivacaine 0.25%, while group BK patients received caudal injectate of 1 ml/kg bupivacaine 0.25% mixed with ketamine 0.5 mg/kg, and group BD patients received caudal injectate of 1 ml/kg bupivacaine 0.25% mixed with dexmedetomidine 1 μg/kg. (springeropen.com)
Additionally, a significant proportion of patients in the Zynrelef arm did not receive opioid analgesia (29% vs 11% for bupivacaine HCl and 2% for saline placebo). (empr.com)

86 trials involving 10 160 patients. (bmj.com)
Results Five randomised controlled trials with 418 children meeting the inclusion criteria were included. (bmj.com)
The researchers searched 13 databases with no language restrictions from inception to Aug 15, 2017, for randomized controlled trials comparing the use of atraumatic needles and conventional needles for any lumbar puncture indication. (medscape.com)
They excluded randomized trials in which no dural puncture was performed (epidural injections) and those without a conventional needle control group. (medscape.com)

Sedación y analgesia em pacientes pediátricos para procedimientos fuera Del área quirúrgica. (bvsalud.org)
Este tipo de dolor es muy común en pacientes con cáncer. (bvsalud.org)
La infusión intravenosa de lidocaína al 2 % disminuyó el dolor search, data collection, neuropático en los tres pacientes del estudio, sin embargo, el alivio fue transitorio y el efecto positivo se perdió con el paso writting, revision y edditing. (bvsalud.org)

Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. (thoracic.org)

Twelve (1.3%) patients required intramuscular (IM) ketamine subsequently. (annals.edu.sg)

A total of 93.1% received 50-70% N 2 O, while 177 (19.3%) received pre-planned local/topical analgesia. (annals.edu.sg)

ABSTRACT To determine the efficacy and pregnancy outcome of external cephalic version at 37 weeks gestation, 90 women with a singleton breech fetus in King Hussein Medical Centre who had the procedure were compared with 102 women in a control group in whom the procedure was not attempted. (who.int)

Results: A total of 124 patient records were audited, comprising 62 patient records at baseline and re-audit. (bvsalud.org)

Cancer patients undergoing chemotherapy may be particularly vulnerable to medical errors, as their care often requires use of high-risk medications and must be closely coordinated between multiple physicians. (ahrq.gov)

Anatomy10

Organisms1

Diseases25

Chemicals and Drugs79

Analytical, Diagnostic and Therapeutic Techniques and Equipment106

Psychiatry and Psychology7

Phenomena and Processes23

Anthropology, Education, Sociology and Social Phenomena2

Information Science6

Named Groups2

Health Care46

Geographicals6

Opioids20

Outcomes14

Intravenous15

Morphine15

Respiratory10

Analgesics6

Onset of analgesia1

Anesthesia21

Perioperative adverse events1

Epidural analgesia1

Effective analgesia1

Multimodal analgesia2

Acute9

Produce postsurgical1

Surgical8

METHODS10

Duration5

Opioid-related adverse1

REACTIONS7

Nausea2

Dose11

Clinical16

Adequate2

Fracture6

Pain53

Underwent5

Anesthetic techniques1

Events11

Intrathecal5

Complications4

Spinal1

Orthopedic Surgery1

Systematic review2

Lidocaine2

Significantly1

Intranasal2

Urinary retention1

Doses1

Euphoria1

Inadequate1

Reduce4

Effects3

Severe2

Severity4

0.051

Study8

Centers for Diseas4

Bupivacaine2

Trials4

Pacientes3

Sedative1

Ketamine1

Topical1

Efficacy1

Baseline1

Medications1