• Epidemiology, Incidence, and Prevalence of Neuroendocrine Neoplasms: Are There Global Differences? (nih.gov)
  • Merkel cell carcinoma (MCC), squamous cell carcinoma (SCC), pigmented epithelioid melanocytoma (PEM), and other rare skin neoplasms have a well-known risk to spread to regional lymph nodes. (hindawi.com)
  • Colonic neuroendocrine neoplasms (NENs) are relatively rare tumors with an incidence rate of 0.11-0.21/100,000. (biomedcentral.com)
  • Neuroendocrine neoplasms (NENs) are rare tumors originating from neuroendocrine cells and include a series of heterogeneous tumors. (biomedcentral.com)
  • Many retrospective studies have confirmed that capecitabine combined with temozolomide is effective in neuroendocrine neoplasms. (viamedica.pl)
  • Treatment options for grade 3 neuroendocrine neoplasms are limited, and the overall prognosis is better in the subgroup of patients with grade 3 neuroendocrine tumours. (viamedica.pl)
  • It was a retrospective study in the population of patients with diagnosed grade 3 neuroendocrine neoplasms of different origin treated with capecitabine and temozolomide. (viamedica.pl)
  • Neuroendocrine tumors (NET) constitute a heterogeneous group of rare neoplasms, with a sustained increase in incidence in recent years. (ijhsc.com)
  • Neuroendocrine neoplasms are divided into well-differentiated neuroendocrine tumors (WDNET) and poorly differentiated neuroendocrine carcinomas (PDNEC). (ijhsc.com)
  • 1. The incidence and prevalence of Neuroendocrine Neoplasms (the combination of Neuroendocrine Tumours (NET) and Neuroendocrine Carcinomas (NEC)) have skyrocketed in the last 40 years to the point that many scientists, epidemiologists and Neuroendocrine specialists are starting to use different terminology, commensurate with the math. (ronnyallan.net)
  • Pulmonary carcinoids are well differentiated low to intermediate grade lung neuroendocrine tumours (LNETs), that belong to the group of lung neuroendocrine neoplasms which also include highly aggressive lung neuroendocrine carcinomas (LNECs). (who.int)
  • In the huge spectrum of lung neuroendocrine neoplasms, typical and atypical carcinoids should be considered as a separate biological entity from poorly differentiated forms, harboring peculiar molecular alterations. (springeropen.com)
  • Neuroendocrine neoplasms (NENs) include all tumors derived from the diffuse endocrine system. (springeropen.com)
  • According to the latest WHO classification of thoracic tumors (5th edition, 2021), lung neuroendocrine neoplasms, which account for nearly 20% of all lung primary tumors, are classified into typical carcinoid, atypical carcinoid, small cell lung carcinoma, and large cell lung carcinoma. (medicalimage.ro)
  • Rekhtman N. Lung neuroendocrine neoplasms: recent progress and persistent challenges. (medicalimage.ro)
  • The data presented in this edition of Cancer Incidence in Five The CI5 data include all invasive malignant neoplasms and Continents (CI5) are mainly organised according to anatomical some non-invasive malignant neoplasms For most morphology site However, for some sites, the histological type of cancer codes, a fifth digit /1 or /2 automatically excludes the data entry. (who.int)
  • CONCLUSION: In asymptomatic patients and when biochemical and clinical suspicion of neuroendocrine tumor is strong, you have to perform anatomical and functional investigations to detect these neoplasms. (unime.it)
  • 2020). A molecular map of lung neuroendocrine neoplasms. (who.int)
  • Merkel cell carcinoma (MCC) is a primary cutaneous neuroendocrine tumor. (cdc.gov)
  • Nonmelanoma skin cancer with potential metastatic spreading to regional lymph nodes regroups skin lesions like high-risk squamous cell carcinoma (SCC), Merkel cell carcinoma (MCC), and pigmented epithelioid melanocytoma (PEM). (hindawi.com)
  • The following review highlights the topics of actinic keratoses, basal cell carcinoma, squamous cell carcinoma, Kaposi's sarcoma, and Merkel cell carcinoma. (jcadonline.com)
  • The cause of death has been given as Merkel Cell Carcinoma, a type of Neuroendocrine Carcinoma of the skin. (ronnyallan.net)
  • Read more about Merkel Cell Carcinoma on Dana Farber - click here Many people in US and elsewhere will have heard of Jimmy and love his music. (ronnyallan.net)
  • Merkel cell carcinoma (MCC) is a rare, aggressive, and often fatal neuroendocrine skin cancer. (medscape.com)
  • Merkel cell carcinoma on a patient's sun-exposed forearm. (medscape.com)
  • Merkel cell carcinoma (MCC) is an uncommon neuroendocrine cutaneous carcinoma. (springeropen.com)
  • Merkel Cell Carcinoma (MCC) is an uncommon neuroendocrine cutaneous carcinoma which is characterized by high incidence of early loco-regional relapse and distant metastases (Poulsen 2004 ). (springeropen.com)
  • A month later, this mass was surgically excised and the histology examination showed a poorly differentiated small cell carcinoma, with histopathologic features of a Merkel cell carcinoma. (springeropen.com)
  • Merkel cell carcinoma (MCC) is a rare malignant cutaneous tumor of the elderly that is characterized by an aggressive course with regional nodal involvement, distant metastases and a high rate of recurrence. (ispub.com)
  • We describe two patients of Merkel cell carcinoma presented to us. (ispub.com)
  • Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine tumor thought to be derived from a specialized epithelial cell, the Merkel cell. (ispub.com)
  • Recent updates in the management of merkel cell carcinoma" by Ahmed Nadeem Abbasi, Syed Mustajab Ahmed et al. (aku.edu)
  • Merkel cell carcinoma is an aggressive non-melanomatous cutaneous tumour of neuroendocrine origin with an increasing incidence in the recent years. (aku.edu)
  • Background Merkel cell carcinoma (MCC) is associated with high recurrence rates and poor survival when metastatic disease is present. (bmj.com)
  • Merkel cell carcinoma (MCC) is a rare and potentially aggressive neuroendocrine carcinoma of the skin with an incidence of around 0.5-0.8/100 000. (bmj.com)
  • In 2017, avelumab became the first drug approved by the FDA for metastatic Merkel cell carcinoma in adults and children aged 12 years or older. (medscape.com)
  • [ 20 ] In 2018, another PD-1 inhibitor, pembrolizumab, was approved for adults and children with metastatic or recurrent, locally advanced Merkel cell carcinoma. (medscape.com)
  • Indicated for adults and children with metastatic or recurrent, locally advanced Merkel cell carcinoma. (medscape.com)
  • Merkel Cell Carcinoma of the Head and Neck: Recommendations for Diagnostics and Treatment. (medscape.com)
  • Effect of radiation therapy on survival in patients with resected Merkel cell carcinoma: a propensity score surveillance, epidemiology, and end results database analysis. (medscape.com)
  • Diagnosis and treatment of Merkel cell carcinoma. (medscape.com)
  • Merkel cell carcinoma. (medscape.com)
  • Available at https://www.mayoclinic.org/diseases-conditions/merkel-cell-carcinoma/symptoms-causes/syc-20351030 . (medscape.com)
  • Merkel cell carcinoma: prevention. (medscape.com)
  • Available at https://my.clevelandclinic.org/health/diseases/17971-merkel-cell-carcinoma/prevention . (medscape.com)
  • Merkel cell carcinoma: changing incidence trends. (medscape.com)
  • Uitentuis SE, Louwman MWJ, van Akkooi ACJ, Bekkenk M. Treatment and survival of Merkel cell carcinoma since 1993: a population-based cohort study in the Netherlands. (medscape.com)
  • Clonal integration of a polyomavirus in human Merkel cell carcinoma. (medscape.com)
  • Merkel cell polyomavirus expression in merkel cell carcinomas and its absence in combined tumors and pulmonary neuroendocrine carcinomas. (medscape.com)
  • MicroRNA Expression Patterns Related to Merkel Cell Polyomavirus Infection in Human Merkel Cell Carcinoma. (medscape.com)
  • Faust H, Andersson K, Ekström J, Hortlund M, Robsahm TE, Dillner J. Prospective study of Merkel cell polyomavirus and risk of Merkel cell carcinoma. (medscape.com)
  • Merkel cell carcinoma: two case reports focusing on the role of fluorodeoxyglucose positron emission tomography imaging in staging and surveillance. (medscape.com)
  • Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC. (pnlab.org)
  • Merkel cell carcinoma (MCC) is a highly aggressive, often lethal neuroendocrine cancer. (pnlab.org)
  • Here, we summarize current knowledge on epidemiology, biology and therapy of MCC as conclusion of the project 'Immune Modulating strategies for treatment of Merkel Cell Carcinoma', which was funded over a 5-year period by the European Commission to investigate innovative immunotherapies for MCC. (pnlab.org)
  • Our team based in Seattle conducted a comprehensive review including evolving trends in the management of Merkel cell carcinoma (MCC). (pnlab.org)
  • Molecular Differences Between MCPyV-Negative MCCs and NECs Differentiating Merkel cell polyomavirus-negative Merkel cell carcinomas from neuroendocrine carcinomas is challenging. (medscape.com)
  • Here, we describe the case and management of a previously healthy 67-year-old male in his fifth year of remission after treatment for poorly differentiated large cell neuroendocrine carcinoma of the esophagus. (biomedcentral.com)
  • Large cell neuroendocrine carcinoma (LCNEC) is a rare type of lung cancer that accounts for approximately 3% of lung cancers. (e-acfs.org)
  • Large cell neuroendocrine carcinoma (LCNEC) is a rare subtype of lung cancer, accounting for 1% to 3% of all lung cancers, and is known for its aggressive behavior [ 1 ]. (e-acfs.org)
  • The second group includes large cell neuroendocrine carcinoma (LCNEC) and small cell lung cancer (SCLC). (springeropen.com)
  • Endoscopic ultrasound-guided biopsy revealed poorly differentiated neuroendocrine carcinoma of the esophagus with metastasis to a diaphragmatic lymph node. (biomedcentral.com)
  • Cutaneous metastases of colonic neuroendocrine carcinomas (NECs) are very infrequent, while cases of scalp metastasis are even fewer. (biomedcentral.com)
  • 7 The general incidence of leptomeningeal metastasis in cancers is rising and is thought to be due to (1) prolonged survival from improved supportive care and systemic therapy, (2) poor CNS penetration of targeted therapies, and (3) improved diagnostic imaging techniques. (appliedradiationoncology.com)
  • Medullary thyroid carcinoma ( MTC ) is a rare thyroid malignancy associated with a higher incidence of distant metastasis and poorer prognosis compared with the more frequently encountered well-differentiated papillary and follicular thyroid carcinomas [1, 2] (Figs. (ollibo.de)
  • Some carcinomas can be life threatening or associated with distant metastasis. (touchophthalmology.com)
  • Non-Colorectal Non-Neuroendocrine Liver Metastasis Learn more about the surgical options for these types of liver metastases and outcomes in these patients. (medscape.com)
  • However, it's true to say that the prognosis for differentiated Neuroendocrine Carcinomas (NEC) is generally poorer than the less aggressive Neuroendocrine Tumours (NET).Surgery can be of benefit for localized disease after extensive preoperative imaging. (ronnyallan.net)
  • Most of the studies focused on grade 1 and grade 2 neuroendocrine tumours, mainly of pancreatic origin. (viamedica.pl)
  • There are limited data regarding the efficacy capecitabine with temozolomide in grade 3 neuroendocrine tumours. (viamedica.pl)
  • The new World Health Organisation 2017 classification distinguished well-differentiated grade 3 neuroendocrine tumours from poorly differentiated grade 3 neuroendocrine carcinomas. (viamedica.pl)
  • This study aimed to evaluate response and survival parameters and compare outcomes of treatment of neuroendocrine tumours and carcinomas. (viamedica.pl)
  • The study included 32 patients with grade 3 neuroendocrine tumours treated with capecitabine and temozolomide. (viamedica.pl)
  • The progression-free survival for patients with neuroendocrine tumours was 15.3 months (95% CI: 3.9-30.4), and for patients with neuroendocrine carcinomas it was 3.3 months (95% CI: 2.5-7.1). (viamedica.pl)
  • Median overall survival was 22 months (95% CI: 11.8-22.0) and 4.6 months (95% CI: 2.2-5.9) for patients with tumours and carcinomas, respectively. (viamedica.pl)
  • Five types of duodenal NETs can be distinguished as gastrinomas, somatostatinomas, clinically non-functioning NETs, duodenal gangliocytic paragangliomas, and poorly differentiated neuroendocrine carcinomas. (eur.nl)
  • The treatment did not overcome the aggressive character of neuroendocrine carcinomas and resulted in low response and survival outcomes in comparison to those achieved in tumour therapy. (viamedica.pl)
  • Extrapulmonary small-cell carcinoma (SCC) is a rare neoplasm that shares certain features with its pulmonary counterpart and occurs predominantly in the gastrointestinal tract (GIT). (mdpi.com)
  • This study aimed to investigate cumulative incidence and risk factors associated with chronic pulmonary infection (CPI) development after radiotherapy for lung cancer. (e-crt.org)
  • Pulmonary giant cell neuroendocrine carcinoma (LCNEC) is an unusual kind of non-small cell lung most cancers (NSCLC) with an incidence of roughly 3% of all lung most cancers diagnoses. (inacj.com)
  • More importantly, given the rise and progress in molecular pathology particularly in fields such as pulmonary adenocarcinomas, it is of great current interest to know any molecular variations in post ADT neuroendocrine differentiation and pure NEPC. (healthyprostateclub.com)
  • In 1987, the staging of ampullary carcinomas was added to the tumor, node, metastases (TNM) classification of malignant tumors by the International Union Against Cancer (now the Union for International Cancer Control), and since then, this classification has been used widely. (medscape.com)
  • Because of the low incidence of nonmelanoma skin cancer with potential metastatic spread and the lack of large clinical trials, the use of SLNB in these cases is not well established, and no guidelines are currently available. (hindawi.com)
  • After thymoma, thymic carcinoma is the second most common type of thymus cancer. (wikipedia.org)
  • Early-stage thymic carcinoma is generally asymptomatic, and the development of symptoms is indicative of an advanced stage cancer. (wikipedia.org)
  • Small cell neuroendocrine carcinoma of the uterine cervix (SCNEC) is a rare cancer involving the human papilloma virus (HPV), and has few available treatments. (biomedcentral.com)
  • 1] The incidence of NMSC, which has increased over the past 20 years in the United States, may be related to higher levels of outdoor activities and sun exposure, changes in clothing style, and improved skin cancer detection. (jcadonline.com)
  • In this review, differences in the incidence of prostate cancer and the prevalence of main genetic alterations between Asian and Western populations are discussed. (escholarship.org)
  • We also review the recent findings on the mechanisms underlying neuroendocrine differentiation of prostate cancer and the development of small cell neuroendocrine carcinoma after androgen deprivation therapy. (escholarship.org)
  • a poorly differentiated Neuroendocrine Cancer, Grade 3 by default. (ronnyallan.net)
  • You'll note the title of this post is 'World Neuroendocrine Cancer Day' and that is because (so called) 'NET Cancer Day' is not good awareness. (ronnyallan.net)
  • One of the many observations I make in my private Neuroendocrine Cancer Facebook group is the misunderstandings caused by the use of non-standard terminology combined with a lack of understanding of what is up to date or not. (ronnyallan.net)
  • Neuroendocrine Cancer - normally slow but don't be fooled! (ronnyallan.net)
  • One such sneaky disease is the lesser-known type of cancer that infiltrated my body - Neuroendocrine Cancer. (ronnyallan.net)
  • Cases of colonic NECs are very unusual and data from the Norwegian Registry of Cancer from 1993-2004 showed that the incidence rate of colonic NENs was 0.25/100,000 and 31.5% of colonic NENs were classified as NECs [ 2 ]. (biomedcentral.com)
  • As the baby boomers enter their 60s and 70s, we are seeing a population bump that significantly increases the incidence of this age-sensitive cancer. (medscape.com)
  • The long-term survival rate of lung cancer patients receiving radiotherapy was not low, but the cumulative incidence of CPI gradually increased to 6.8% at 7 years after radiotherapy. (e-crt.org)
  • The incidence of cancer continues to increase according to the recent studies. (scirp.org)
  • Medullary thyroid cancer is a form of thyroid carcinoma which originates from the parafollicular cells (C cells), which produce the hormone calcitonin. (ollibo.de)
  • They are also at an increased risk of developing a type of kidney cancer called clear cell renal cell carcinoma and a type of pancreatic cancer called a pancreatic neuroendocrine tumor. (medlineplus.gov)
  • Opinion: On Rare Cancer Day, what's wrong with a bit of Neuroendocrine Cancer awareness? (ronnyallan.net)
  • Award winning Neuroendocrine Cancer Patient Advocate. (ronnyallan.net)
  • Diagnosed with Metastatic Neuroendocrine Cancer in 2010. (ronnyallan.net)
  • When an outsider looks into the Neuroendocrine Cancer community, it shouldn't be a surprise if their first thoughts were that it was some sort of animal welfare or zoological support group, particularly focused on black and white striped animals. (ronnyallan.net)
  • Neuroendocrine Cancer: Fibrosis - an unsolved mystery? (ronnyallan.net)
  • Background: In some settings, lung cancer incidence appears higher among disadvantaged groups. (who.int)
  • We analyzed the harmonized database of the Lung Cancer Cohort Consortium (LC3) to assess the relationship between socioeconomic status and lung cancer incidence across different world regions. (who.int)
  • Background: The Nordic countries have benefited from steep declines in cervical cancer incidence rates, as a consequence of the implementation of nationwide screening programmes. (who.int)
  • We provided an assessment of the magnitude and temporal trends of cervical cancer incidence by socioeconomic. (who.int)
  • Disparities in cancer-specific incidence, mortality, and survival exist worldwide. (who.int)
  • Transitional cell carcinoma (TCC) accounts for approximately 95% of bladder cancers and is the 4th most common cancer among men and the 10th most common in women, in the United States. (thesecretsofmedicine.com)
  • The overall incidence of bladder cancer appears to be increasing, probably due to the general aging of the population and the latent effects of tobacco abuse and industrial carcinogens. (thesecretsofmedicine.com)
  • Immune Checkpoint Inhibitor-induced Cutaneous Toxicities This study aimed to identify the clinical characteristics and overall incidence of cutaneous immune-related adverse events among cancer patients receiving immune checkpoint inhibitors. (medscape.com)
  • Vitamin D Supplementation and Risk of Keratinocyte Cancer Might vitamin D supplementation reduce the incidence of keratinocyte cancers or other actinic lesions? (medscape.com)
  • 2020). Opium use and subsequent incidence of cancer: results from the Golestan Cohort Study. (who.int)
  • Other carcinomas with malignant spread to the thymus are on the differential diagnosis and must be excluded, as they may appear similar to thymic carcinoma on histopathological examination. (wikipedia.org)
  • Histologically, this malignant epithelial pancreatic neoplasm of the exocrine cells is characterized by multiple lines of differentiation (acinar, ductal, mesenchymal, neuroendocrine) and the presence of squamoid nests. (orpha.net)
  • Pauniaho SL, Salonen J, Helminen M, Vettenranta K, Heikinheimo M, Heikinheimo O. The incidences of malignant gonadal and extragonadal germ cell tumors in males and females: a population-based study covering over 40 years in Finland. (cancercentrum.se)
  • We have also reviewed the literature concerning gastroenteropancreatic neuroendocrine carcinomas (GEP-NECs) in this article. (biomedcentral.com)
  • One hundred years after "carcinoid": epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States. (unina.it)
  • According to the degree of differentiation, NENs have been divided into well differentiated NENs and poorly differentiated NENs in the 2010 World Health Organization classification of tumors of the digestive system, with the former being termed a neuroendocrine tumor (NET), and the latter, a neuroendocrine carcinoma (NEC) [ 1 ]. (biomedcentral.com)
  • It is unclear if the morphologic pattern and appearance of neuroendocrine differentiation varies based on the type of anti-androgen regimen. (healthyprostateclub.com)
  • It shows significant acinar cell differentiation but also ductal, mesenchymal and neuroendocrine differentiation. (orpha.net)
  • While still in preliminary stages, agents, such as ingenol mebutate, vismodegib, and sirolumus, may become integral drugs in the armamentarium of managing cutaneous carcinoma. (jcadonline.com)
  • Carcinoid heart disease (CHD) is a rare and potentially lethal manifestation of an advanced carcinoid (neuroendocrine) tumor. (karger.com)
  • Due to the evolution of imaging techniques, the incidence of carcinoid tumors has slightly increased over the last decades, currently representing 2% of primary lung tumors, with a predominance of typical carcinoid. (medicalimage.ro)
  • It has an estimated annual incidence ranging from 0. (ollibo.de)
  • It is a very rare tumor with an annual incidence of approximately 0.42 per 100,000. (ispub.com)
  • With an annual incidence estimated at 1/100,000, paragangliomas represent 10% of catecholamine secreting tumors. (unime.it)
  • however, the epithelial cells in thymic carcinoma appear abnormal histologically, as they are infiltrative and not arranged in a lobular pattern as seen in the normal thymus. (wikipedia.org)
  • Thymic carcinoma represents 20% of tumors derived from thymic epithelial cells. (wikipedia.org)
  • 2021). Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence. (who.int)
  • Il s'agitd'une étude rétrospective et descriptive portant sur tous les cancers gynécologiques reçus en oncologie entre le 1erJanvier 2016 et le 31 Décembre 2021. (bvsalud.org)
  • The accuracy of the preoperative diagnosis of ampullary carcinoma increased from 27% to 73% after the introduction of fiberoptic endoscopy. (medscape.com)
  • Of the 24 patients with carcinomas of the ampulla described by Mori et al, 5 had stage I disease (20.8%), 11 had stage II disease (45.8%), 7 had stage III disease (29.2%), and 1 had stage IV disease (4.2%) at diagnosis. (medscape.com)
  • Diagnosis of thymic carcinoma is based on a combination of clinical, radiologic, and biopsy findings. (wikipedia.org)
  • This ENETS guidance paper, developed by a multidisciplinary working group, provides up-to-date and practical advice on the diagnosis and management of digestive neuroendocrine carcinoma, based on recent developments and study results. (ronnyallan.net)
  • Xanthogranulomatous cholecystitis (XGC) mimics Gallbladder carcinoma (GBC) in both preoperative and intra-operative settings and the patient may undergo an unnecessary radical cholecystectomy which is associated with a greater morbidityrather than a cholecystectomy alone.We postulated that a pre-operative diagnosis of XGC might benefit patients by avoiding radical procedures and attempted to identify the features of XGC which would differentiate it from GBC before and during surgery. (medicinelakex1.com)
  • Similarly, under Carcinoma, specific renamed or deleted in later revisions of tumour classifications. (who.int)
  • I. To assess the recommended phase 2 dose of belinostat in combination with tremelimumab and durvalumab in advanced solid tumors harboring ARID1A mutations with focus on urothelial carcinoma. (bcan.org)
  • Histologically confirmed urothelial carcinoma with metastatic disease or with unresectable, locally advanced disease. (bcan.org)
  • A few studies have reported that SOX2 is overexpressed in cervical squamous cell carcinoma (SCC), and plays an important role in the progression from squamous dysplasia to SCC. (biomedcentral.com)
  • Circulating Vascular Endothelial Growth Factor and Vascular Cell Adhesion Molecule in Laryngeal Squamous Cell Carcinomas.Journal of R hinolaryngo-Otologies, 2(3), 53-58. (dokran.net)
  • MCC is about 30 times less common than melanoma and far less common than basal or squamous cell carcinoma, and the clinical features of MCC are not extremely specific. (medscape.com)
  • In particular, these findings are associated with periocular non-melanoma skin cancers, namely basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). (touchophthalmology.com)
  • Gene expression imputation identifies candidate genes and susceptibility loci associated with cutaneous squamous cell carcinoma. (kaiserpermanente.org)
  • Predictors of Survival After Head and Neck Squamous Cell Carcinoma in South America: The InterCHANGE Study. (who.int)
  • 2022). The relationship between blood pressure and risk of renal cell carcinoma. (who.int)
  • L'objectif de cette étude était de déterminer la fréquence des cancers gynécologiques en pratique oncologique à Lomé et d'en étudier les aspects épidémiologiques et histo-cliniques. (bvsalud.org)
  • This update on the cutting-edge clinical and dermpathologic research will assist the dermatologist in approaching, diagnosing, and managing nonmelanoma skin carcinoma. (jcadonline.com)
  • In this review, the authors describe common clinical signs of eyelid malignancies and detail features of some of the more common carcinomas found in the periocular region. (touchophthalmology.com)
  • Neuroendocrine tumors (NETs) are rare tumors originating from enterochromaffin cells of the neuroendocrine system of the bronchial and gastrointestinal tracts. (eur.nl)
  • In addition to GEP-NETs, there are several subtypes of NETs including pheochromocytoma, paraganglioma, medullary thyroid carcinoma, Markel cell carcinoma and bronchial carcinoids. (intheranostics.com)
  • Specifically, we sought to examine whether there are differences in incidence, prevalence, distribution (by primary tumor site, tumor grade, tumor stage at presentation), and overall survival of GEP NETs between different regions of the world. (nih.gov)
  • Here, we review the literature and report a unique case of a patient with a vague presentation of esophageal neuroendocrine carcinoma as he enters his sixth year of survival following neoadjuvant chemoradiotherapy. (biomedcentral.com)
  • The cumulative incidence of CPI and overall survival (OS) were estimated using the Kaplan-Meier method, and a multivariable Cox proportional hazards analysis was performed to identify risk factors associated with CPI development. (e-crt.org)
  • The histopathology examination showed infiltration of the thyroid gland by a neuroendocrine carcinoma with characteristics compatible with MCC. (springeropen.com)
  • Moertel CG, Kvols LK, O'Connell MJ, Rubin J. Treatment of neuroendocrine carcinomas with combined etoposide and cisplatin. (unina.it)
  • They originate in neuroendocrine cells, the most common are those of the gastrointestinal system and most are sporadic, although they can be part of hereditary syndromes. (ijhsc.com)
  • MCC express both neuroendocrine (neuron-specific enolase, synaptophysin, chromogranin) and cytokeratin markers (cytokeratin 20, as a paranuclear dot, CAM 5.2) and is negative for S100 and the common leukocyte antigen ( 2 ). (ispub.com)
  • AIM: Paragangliomas are neural crest-derived neuroendocrine tumors, originating from paraganglia, which are dispersed neuroendocrine organs characterized by catecholamine and peptide-producing cells. (unime.it)