Inbred mouse strain mice inbred balb c. Medical search. Frequent questions

Common inbred strains include BALB/c, C3H, C57BL/6 and DBA. (uwm.edu)
Recombinant inbred strain, progenitor cross: (BALB/cBy female X C57BL/6By male). (jax.org)
Inbred strains of mice can be classified into 3 categories according to their resistance to infection with S.typhimurium: susceptible (BALB/c, C57BL/6, C3H/He), intermediate (DBA/2, C75L) and resistant (A, CBA). (prosci-inc.com)
Using a pair of black mice from the Granby farm, Little develops the C57BL and C57BR strains. (jax.org)
C57BL/6J is the most widely used inbred strain and the first to have its genome sequenced. (ncard.org.au)
Congenic BALB/c CL4 strain expressing C57Bl/6 Thy 1.1 allele. (ncard.org.au)
JAX stock No# 002216 or C57BL/6J isogenic Rag1 knock-out strain is also available as Stock No. 034159 . (ncard.org.au)
C57BL/6 (B6), C57BL/10 (B10), and SJL mice showed markedly suppressed secondary anti-DNP responses when infected. (uky.edu)
We offer pharmacokinetic (PK) studies in widely used murine inbred (C57BL/6, BALB/c), or custom strains. (flywithabird.com)
In the present study a nest-building protocol was established using four different inbred mouse strains (CD1, BALB/c, C57Bl/6J, C3H) before assessing AD and FTD tau transgenic mice of Line 1 (L1) and Line 66 (L66) in this paradigm. (bvsalud.org)
Reproductive performance consisting of mean litter size, number of pups that wean (wean: born ratio) and mean reproductive index of three inbred mice strains, which are BALB/cMlac, C57BL/6Mlac and DBA/2Mlac, were investigated to provide some basic information on the breeding and maintaining of a foundation colony. (mahidol.ac.th)
For instance, C57BL/6J mice are resistant to hepatic, renal and cardiac fibrosis but susceptible to pulmonary and intestinal fibrosis. (biomedcentral.com)
CB6F1 hybrid mice, a cross between C57BL/6 and Balb/c mice, were tested for learning and memory using a radial water tread maze. (antpublisher.com)
HET3 mice used in this program are (F2) offspring of CByB6F1/J and C3D2F1/J (combining BALB/cBy, C57BL/6, C3H, and DBA/2) strains. (jax.org)
J:235854 lists J:27148 as the reference for these mice but then describes them as "B6C3F1" when the mice in the given reference were C57BL/6J mice fostered on C3Hf/Nctr mice. (jax.org)
While langerin+ cells are observed in comparable numbers and with comparable phenotypes in the epidermis, two distinct DC subsets bear langerin in peripheral, skin-draining lymph nodes of BALB/c mice (CD11c(high) CD8alpha(high) and CD11c(low) CD8alpha(low)), whereas only the latter subset is present in C57BL/6 mice. (cnrs.fr)
The CD11c(high) subset is detected in mesenteric lymph nodes and spleen of BALB/c mice, but is virtually absent from C57BL/6 mice. (cnrs.fr)

There is mounting evidence suggesting that inbred mouse strains with different genetic backgrounds demonstrate variable susceptibility to a fibrotic injury. (biomedcentral.com)
We performed a systematic review of the literature describing strain and organ specific response to injury in order to determine whether genetic susceptibility plays a role in fibrogenesis. (biomedcentral.com)
There is evidence that mouse strain differences influence susceptibility to fibrosis and this appears to be organ specific. (biomedcentral.com)
The majority of genomic studies used to identify susceptibility pathways involved in disease pathologies have been performed in the mouse. (biomedcentral.com)
Mice are also easy to breed with a short generation time and a short life span allowing direct study of disease development and can accurately eludicidate how genetic sequences may vary in different strains and result in susceptibility to fibrotic pathologies. (biomedcentral.com)
Strain susceptibility and resistance to 1,2-dimethylhydrazine-induced enteric tumors in germfree rats (40146). (cdc.gov)

Inhibition of EHMT2 expression or activity in human ERMS cell lines reduced DKK1 expression and elevated canonical Wnt signaling resulting in myogenic differentiation in vitro and in mouse xenograft models in vivo. (elifesciences.org)

A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain. (jax.org)
In a retrospective study of 142 tumors observed over a period of 3 years, myoepitheliomas occurred spontaneously in A/HeJ, A/J, BALB/cJ, BALB/cByJ, LLC.A/Ckc, and NOD/Lt inbred strains of mice. (jax.org)
Lathrop sends mice that developed tumors to Leo Loeb at the University of Pennsylvania , who publishes pioneering papers on cancer. (jax.org)
L. C. Strong breeds a Bagg albino with an albino from Little 's stock and starts the first of many tumor-prone strains, called the A strain, known for mammary and lung tumors. (jax.org)
Concordantly, 55% of Ncadk.i. mice harboring a heterozygous p53 deletion developed malignant and invasive tumors. (biomedcentral.com)
Thus, we provide a new mouse model to investigate the molecular mechanisms of fibrocystic mastopathy and the transition from benign to malignant tumors. (biomedcentral.com)

The tumor phenotype in mice takes eight weeks to develop from the H-Ras and shp53 model. (genengnews.com)
The tumor phenotype is revealed when mice appear lethargic and have an enlarged head. (genengnews.com)
BALB/c nude mice: A spontaneous mutation in Foxn1 nu induces abnormal hair growth (nude phenotype). (ncard.org.au)
Mice homozygous for the severe combined immune deficiency spontaneous mutation Prkdcscid, commonly referred to as scid, are characterized by an absence of functional T cells and B cells, lymphopenia, hypogammaglobulinemia, and a normal hematopoietic microenvironmentsevere combined immune deficient phenotype on Non obese diabetic genetic background. (ncard.org.au)

Adult p107-null mice had elevated numbers of proliferating progenitor cells in their lateral ventricles. (rupress.org)

Histamine-induced microvascular leakage in pial venules: differences between the SJL/J and BALB/c inbred strains of mice. (tamu.edu)
Differences evident between the L1 and L66 tau transgenic mouse models are likely due to the different human tau species expressed in these mice. (bvsalud.org)
Quantitative trait locus (QTL) analysis is a common genetic approach that has been used in the past two decades to identify loci involved in differences in fibrotic response between inbred strains of mice [ 9 ]. (biomedcentral.com)
Based on the data obtained, strain differences and age-related changes in the spontaneous behavior of female mice of the CBRB and BALB/cJ strains were revealed. (labanimalsjournal.ru)
Here, we describe striking differences in langerin-expressing cells between inbred mouse strains. (cnrs.fr)
Similar differences are observed in other mouse strains. (cnrs.fr)
A final vaccine analysis using a lethal influenza virus challenge showed that despite the differences in the immune responses observed in the mice, the mice had very similar patterns of protection. (mdpi.com)

Laboratory mice are usually of the species Mus musculus. (wikipedia.org)
Other mouse species sometimes used in laboratory research include two American species, the white-footed mouse (Peromyscus leucopus) and the North American deer mouse (Peromyscus maniculatus). (wikipedia.org)
In 1902 Lucien Cuénot published the results of his experiments using mice which showed that Mendel's laws of inheritance were also valid for animals - results that were soon confirmed and extended to other species. (wikipedia.org)
More laboratory mice are used in research every year than any other animal species. (uwm.edu)
Three mammalian species are reservoir competent: the white-footed mouse ( Peromyscus leucopus ), raccoon ( Procyon lotor ), and gray squirrel ( Sciurus carolinensis ), although serologic and molecular evidence has suggested that numerous other small, medium, and large mammals may also be reservoirs ( 1 , 3 ). (cdc.gov)
FXGs were previously identified in mouse, rat, and human brains in a conserved subset of neuronal circuits but with species-dependent developmental profiles. (biorxiv.org)

CD4 TCR transgenic mouse whose CD4 T cells predominantly recognise the MHC class II (I‑A d )‑restricted TCR specific for the PR8 influenza HA peptide 126-138 (HNTngvtaacshe) ( PMID: 7889402 ). (ncard.org.au)

In the early part of the 20th century, Harvard undergraduate Clarence Cook Little was conducting studies on mouse genetics in the laboratory of William Ernest Castle. (wikipedia.org)
Clarence Cook Little begins to develop the first inbred strain, designated DBA for dilute, brown, and non-agouti. (jax.org)

In contrast, AP-Variant 1 does not infect the white-footed mouse, DBA/2, and severely immunocompromised (SCID) mice ( 8 ). (cdc.gov)
These animals carry the severe combined immune deficiency mutation ( scid ) on the BALB/c background. (ncard.org.au)

CD8 TCR transgenic mouse whose CD8 T cells predominantly recognise the MHC class I (H-2K d ) restricted CL4 epitope of PR8 influenza HA protein. (ncard.org.au)

The laboratory is also the world's source for more than 8,000 strains of genetically defined mice and is home of the Mouse Genome Informatics database. (wikipedia.org)
No LPS-reactive cells but normal frequencies of lipoprotein-reactive cells were found in C3H/HeJ mice, genetically nonreactive to LPS. (silverchair.com)
The use of induced and spontaneous mutant mice and genetically engineered mice (and combinations thereof) to study cancers and other aging phenotypes to advance improved functional human life spans will involve studies of aging mice. (jax.org)
Increased recognition of expected phenotypes, experimental variables that influence phenotypes and research outcomes, and experimental design options and rationales can maximize the utility of genetically engineered mice (GEM) models to translational research on aging. (jax.org)

Together they generated the DBA (Dilute, Brown and non-Agouti) inbred mouse strain and initiated the systematic generation of inbred strains. (wikipedia.org)

In a mouse model of LPS-induced acute inflammation, DSO2-ONJ demonstrated anti-inflammatory activity by inhibiting the production of the pro-inflammatory interleukin-6. (cnrs.fr)

Common laboratory inbred mouse strains such as BALB/c and C57Bl6/J form the backbone of much of our pre-clinical work. (ncard.org.au)
C57BL6, 129, and FVB/N strains are emphasized because of their widespread use in the generation of knockout, transgenic, and conditional mutant GEM. (jax.org)

This causes the genes to become homozygous (same strain) at nearly all the loci on the chromosomes. (uwm.edu)
homozygous nude mice lack T cells and suffer from a lack of cell-mediated immunity. (ncard.org.au)
Mice homozygous for the Rag1 tm1Mom mutation produce no mature T cells or B cells. (ncard.org.au)
For microarray analysis, muscle from three age-matched, wild-type +/+ Balb/By, inbred strain mice (WT) and 3 female and 3 male homozygous sfx/sfx mice were used. (biomedcentral.com)

The Ferric Chloride - induced thrombosis technique allows assessment of thrombosis progression in coisogenic strains, and in isogenic mice dosed with study compounds. (flywithabird.com)

One naturally occurring genetic defect in mice results in an animal with no hair that is called a nude. (uwm.edu)

These FXG properties are conserved in both mice and rats, suggesting these granules may support conserved cellular functions. (biorxiv.org)

Plastic restraint devices can be used to hold mice and other rodents for longer periods of time. (uwm.edu)

Peter Gorer shows in mouse studies at JAX that transplant rejection is primarily governed by what he calls the H2 genetic locus, later described as the major histocompatibility complex, a key component of immunity. (jax.org)
It was generated to be used as a base population of broad genetic basis and as the control line of an experiment of artificial body-conformation selection which gave rise, among others, to CBi − and CBi/L mice lines [ 7 , 8 ]. (biomedcentral.com)
Such mouse strain studies may prove useful in elucidating the genetic as well as epigenetic factors in humans that could help determine why some people are more susceptible to the development of certain organ specific fibrosis than others. (biomedcentral.com)
In this study, we disrupted circadian rhythms in female and male mice using both environmental (i.e., shifting diurnal cycles) and genetic (i.e. (mdpi.com)

Forty myoepitheliomas were tested by the avidin-biotin complex technique with a panel of antisera specific for mouse keratins, intermediate filaments, and other cytoskeletal proteins to determine the cell type from which this neoplasm originated. (jax.org)

The laboratory mouse genome has been sequenced and many mouse genes have human homologues. (wikipedia.org)
Two strains may be bred together to produce a mixture of the genes of each strain. (uwm.edu)
Using a lentiviral vector containing either H-Ras oncogene and a hairpin targeting p53 or both tumor suppressor genes, NF-1 and p53, Dr. Friedmann-Morvinski can induce the formation of a glioma tumor in mice injected in the brain. (genengnews.com)
1939 International Committee on Standardized Nomenclature for Mice begins, bringing order to the naming of mice and their genes. (jax.org)
Both H-2-linked and -nonlinked genes appeared to be responsible for the regulation of the immunosuppression, since the suppressive effect of infection in B10.D2 mice, which have the B10 background and the same H-2 haplotype as BALB/c, was weaker than that of B10 mice, but stronger than in BALB/c mice. (uky.edu)
In order to identify the genes that regulate muscle development through Vitamin C (VC) pathway, we analyzed the gene expression profile in mouse muscle from femur. (biomedcentral.com)
2) Some of dystrophin relevant genes are also affected in the sfx mice. (biomedcentral.com)

Old CB6F1 male mice (30 months of age) had severe cognitive impairment, while it was virtually absent in young (6 months old) male mice. (antpublisher.com)

The investment in training should be outweighed by the benefits observed with more reliable behavioral and physiological responses in the mice. (uwm.edu)
Halsey Bagg develops the BALB /c ( Bagg albino) mouse for behavioral experiments. (jax.org)
In a previous study, we characterized behavioral phenotypes of a mouse model generated by a sequential process of early-life social stress imitating child abuse or maltreatment composed of maternal separation (MS), social defeat (SD), and social isolation (SI). (encephalitisjournal.org)
Solovieva A.S. , Aronov D.A. , Shubernetskaya O.S. , Kalinin M.A. , Moiseeva Е.V. Express-modification of cylinder test for assessing the behavioral parameters of young and old cbrb and BALB/CJ mice. (labanimalsjournal.ru)
Kalinin M.A. - participation in the performance of behavioral tests, in the maintenance of the collection, and experimental mice. (labanimalsjournal.ru)

The strain MOLF/Ei is highly susceptible to the infection, has an unique TLR5 haplotype and a lower expression of TRL5. (prosci-inc.com)
BALB/c based mouse model in which the administration of diphtheria toxin (DT) leads to specific depletion of regulatory T cells (Treg) due to expression of DT receptor-enhanced GFP under the control of the Foxp3 promoter. (ncard.org.au)
Asbestos induced mesothelioma mouse model in which expression of the Simian Virus 40 large T antigen (SV40 TAg) is controlled by mesothelin tissue‑specific promoter. (ncard.org.au)
In these mice, N-cad was efficiently expressed in the E-cad expression domains. (biomedcentral.com)
Because muscle forces are a strong determinant of bone structure, particularly during the process of growth and development, we examined the gene expression of muscle in sfx mice. (biomedcentral.com)
Our results indicated that 1) The expression of Myogenic factor 6 (Myf6) gene in sfx mice is increased in both female and male mice, while the increase in male mice is much higher than that in female mice. (biomedcentral.com)
The expression of creatine kinase muscle type (Ckb) and Cdc42 binding protein kinase beta (Cdc42bpb), on the other hand, although at a low level are increased in both sfx and wild type mice. (biomedcentral.com)

These mice have deficiencies in their immune systems and thereby prove valuable in the study of immune diseases and cancer. (uwm.edu)
7], the authors associated a poor response to IFN-β treatment with Th17-type immune responses in EAE mice. (nartsignaling.com)
Immunodeficient mouse strains are invaluable when assessing the role of immune cell subsets in anti‑tumour immunity. (ncard.org.au)
Macrophage-mediated suppression of immune responses in Toxoplasma-infected mice. (uky.edu)
Dive into the research topics of 'Macrophage-mediated suppression of immune responses in Toxoplasma-infected mice. (uky.edu)
This study determined the immune correlates induced by serial dilutions of rAd vaccines delivered intramuscularly (IM) and intranasally (IN) to mice and rats. (mdpi.com)
Title : Pulmonary immune responses to Aspergillus fumigatus in an immunocompetent mouse model of repeated exposures Personal Author(s) : Buskirk, Amanda D.;Templeton, Steven P.;Nayak, Ajay P.;Hettick, Justin M.;Law, Brandon F.;Green, Brett J.;Beezhold, Donald H. (cdc.gov)

Insect larvae such as tobacco hornworm can accelerate and economize preclinical research by complementing classic laboratory animals such as rats and mice. (uni-giessen.de)

The Ferric Chloride- induced thrombosis model is a widely used technique to produce thrombus formation in the left carotid artery of the mouse. (flywithabird.com)

The mouse has since been used extensively as a model organism and is associated with many important biological discoveries of the 20th and 21st Centuries. (wikipedia.org)
The first paper will examine correlates among attending, impulsive behavior, and short-term remembering in a mouse model of Alzheimer's disease. (abainternational.org)
The aim of this study was to evaluate cognitive impairment in a mouse model of AD-associated amyloidosis. (abainternational.org)
Potential factors contributing to lack of impairment in DMTP/3CSRT performance in the APPswe/PS1dE9 double mouse model of AD-associated amyloidosis will be discussed. (abainternational.org)
J:259852 Mouse Genome Informatics and the WTSI Mouse Genomes Project, MGI Strain Genome Feature and Gene Model Load. (jax.org)
The Jackson Laboratory has made fundamental contributions to biomedical research, including cancer genetics and establishing the mouse as the premier research animal model. (jax.org)
The model is simple and well-described ( ref). and typical study requires 8-10 mice/ group to be completed. (flywithabird.com)
The results obtained support the conclusion that the system M-406 plus the inbred mouse lines CBi, CBi − and CBi/L, is a good murine model to study the process of tumor immunoediting. (biomedcentral.com)
Mice provide a suitable model for the study of human genetics because more than 95% of the genome is identical. (biomedcentral.com)
We recently addressed the question of interchangeability of the two cadherins by generating a mouse model in which N-cad cDNA was introduced into the E-cad locus. (biomedcentral.com)
The aging CB6F1 mouse would be a potential model to study the relationship between changes in brain morphometry and cognitive impairment and the identification of possible therapeutic targets. (antpublisher.com)
The mouse model was sequentially subjected to maternal separation (MS), social defeat (SD), and social isolation (SI) in that order (MS/SD/SI model). (encephalitisjournal.org)
The spontaneous bone fracture (sfx) mouse is a mouse model which is deficient in the synthesis of VC because of the deletion in Gulo gene. (biomedcentral.com)
This confirms the use of CBRB mice as an adequate model of parkinsonism. (labanimalsjournal.ru)
We also reported an L-arginine induced pancreatitis model in mice using a two injection protocol (6). (pancreapedia.org)

LPS-reactive B cells yielding IgM- and IgG-PFC responses could be found in mesenteric lymph nodes, bone marrow, thymus, thoracic duct, and peripheral blood of 6- to 8-wk old mice. (silverchair.com)

Balb/C, C3H, DBA/2) are also highly susceptible to infection ( 1 , 6 , 7 ). (cdc.gov)
However, BALB/c mice are resistant to pulmonary fibrosis but susceptible to hepatic fibrosis. (biomedcentral.com)

The number of LPS- and of lipoprotein-reactive B cells in spleen was dependent upon the age of the mouse. (silverchair.com)
15-11C5 is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from Balb/c mice immunized with WAG/Rij spleen cells. (hycultbiotech.com)

In the three strains tested, the penicillin G and D-penicillamine injections resulted in approximately dose-dependent responses. (go.jp)
The infected DBA/2 and C3H/He mice produced moderately suppressed responses. (uky.edu)
However, in BALB/c mice, the responses were not affected even by inoculation with 1 × 10 4 organisms. (uky.edu)
The difference in the suppressive effect of infection between B6 and BALB/c mice was also observed in the primary anti-DNP antibody responses to DNP-KLH. (uky.edu)
When immunized IM, mice had substantially higher antibody responses at the higher vaccine doses, whereas, the IN immunized mice showed a lower response to the higher rAd vaccine doses. (mdpi.com)
The IM immunized mice and rats also showed significant dose-dependent T cell responses to the rAd vaccine. (mdpi.com)
Additionally, the highest dose of vaccine in mice and rats did not improve the T cell responses. (mdpi.com)

The mutagenicity of 4-phenyl-1, 3-dithia-2-thioxo-cycLopent-4-ene (DT827B) was examined in reverse mutation tests using Salmonella tryphimurium and Escherichia coli, in the chromosomal aberration test with Chinese hamster ovary (CHO) cells, and in the micronucleus test using mice bone-marrow. (go.jp)
Re-evaluation of 1,2-dimethylhydrazine in the mouse bone marrow micronucleus assay: Observation of a positive response. (cdc.gov)

The most commonly used methods for catching and picking up mice are grasping the animal near the tip of the tail, between thumb and forefinger, or by grasping the tail near the base or the neck between the ends of a smooth tipped forceps. (uwm.edu)
BALB/cJ : a commonly used inbred mouse stain. (ncard.org.au)

The purpose of the study was to analyze spontaneous behavior of young and old females of the original CBRB inbred strain with signs of parkinsonism after 80 weeks of age and females of the standard BALB/cJ strain of the same ages using express-test. (labanimalsjournal.ru)
The express modification of the cylinder test enabled to confirm not only the previously discovered motor traits of female CBRB mice, but also certain non-motor changes in spontaneous behavior that are similar to characteristics of patients with Parkinson's disease. (labanimalsjournal.ru)

There is a significant difference in myopathy and gene regulations in muscle of sfx mice between female and male mice. (biomedcentral.com)

L. C. Dunn breeds Strain 129, which later proves to have a high incidence of testicular cancer. (jax.org)
After inbreeding for 20 generations, a surprisingly high incidence of hydronephrosis was encountered and we finally obtained a strain of mice with a very high incidence of severe hydronephrosis affected on both sides of kidney and in both sexes as the process of inbreeding has been increased. (mahidol.ac.th)

Inbred strains are the result of at least 20 generations of brother-sister mating. (uwm.edu)
From then on, a regular system of inbreeding involving full-sib (FS) mating was applied and maintained for more than 30 generations giving rise to CBi/L FS, CBi − FS and CBi FS lines. (biomedcentral.com)

Female mice aged 5 - 6 months were assessed in the home cage over a period of 7 days with nest-building behaviour scored by three independent experimenters at intervals of 1-, 2- and 7-days post nestlet introduction. (bvsalud.org)
BALB/c mice were more proficient than CD1 and C3H mice, while all strains displayed similar nest-building behaviour by day 7. (bvsalud.org)

To date, the Mouse Genome Database through The Jackson Laboratory, lists 24 QTL in mice associated with fibrosis of which all but 3 are phenotypes in the lung. (biomedcentral.com)

Mice have been used in biomedical research since the 17th century (from May 30, 1678) when William Harvey used them for his studies on reproduction and blood circulation and Robert Hooke used them to investigate the biological consequences of an increase in air pressure. (wikipedia.org)
Recent studies that compared the prevalence of AP-ha to AP-Variant 1 in tick populations showed the variant to be the predominant strain at 2 of 3 sites and suggest that AP-Variant 1 is common in nature ( 4 , 5 ). (cdc.gov)
The white-footed mouse serves as a natural reservoir for AP-ha, and laboratory studies have shown that numerous inbred strains of mice (e.g. (cdc.gov)
Data were collected from studies that were deemed eligible for analysis based on set inclusion criteria, and findings were assessed in relation to strain of mouse, type of injury and organ of investigation. (biomedcentral.com)
A total of 44 studies were included covering 21 mouse strains and focusing on fibrosis in the lung, liver, kidney, intestine and heart. (biomedcentral.com)

APPswe/PS1dE9 double transgenic (Tg) male and female mice and non-transgenic (non-Tg) littermates were trained on a delayed-matching-to-position (DMTP) or 3-choice serial reaction time (3CSRT) task. (abainternational.org)
Previously, a low incidence of mild hydronephrosis was observed mostly in male mice and found only on the right kidney. (mahidol.ac.th)
Pathological analysis suggests that the diameters of male and female of sfx mice are smaller than that of Wt mice. (biomedcentral.com)
Alcohol consumption and preference, as well as food and water consumption, total caloric intake, and weight were assessed in adult female and male Clock Δ19/Δ19 mutant mice or wild-type (WT) litter-mates, housed under a 12-hour:12-hour light:dark (L:D) cycle or a shortened 10-hour:10-hour L:D cycle. (mdpi.com)

Abnormal brain oscillations were observed in the MS/SD/SI mice. (encephalitisjournal.org)

As a general rule, inbred mice tend to have longer gestation periods and smaller litters than outbred and hybrid mice. (wikipedia.org)

The L-arginine doses used in rats did not cause pancreatitis in mice. (pancreapedia.org)

Mice belong to the Euarchontoglires clade, which includes humans. (wikipedia.org)
This close relationship, the associated high homology with humans, their ease of maintenance and handling, and their high reproduction rate, make mice particularly suitable models for human-oriented research. (wikipedia.org)
Mice are mammals of the clade (a group consisting of an ancestor and all its descendants) Euarchontoglires, which means they are amongst the closest non-primate relatives of humans along with lagomorphs, treeshrews, and flying lemurs. (wikipedia.org)

Little and Castle collaborated closely with Abbie Lathrop who was a breeder of fancy mice and rats which she marketed to rodent hobbyists and keepers of exotic pets, and later began selling in large numbers to scientific researchers. (wikipedia.org)

Inbred and hybrid mouse strains can be useful models to investigate cognitive impairment and morphological changes at older ages. (antpublisher.com)

For females of both strains, an age-related decrease in the number of rears with the support was found. (labanimalsjournal.ru)

In the tau mouse models, L66 presented with impaired nesting compared to wild-type on days 1 and 2 (not day 7), whereas L1 performed like wild-type on all days. (bvsalud.org)

Young mice ( pups) should be grasped by the cupping the hands around the whole body or by grasping the skin across the shoulder blades with a forceps. (uwm.edu)

CBi is an inbred mouse strain derived from an outbred population generated by crossing BALB/c, Rockland, NIH and Swiss mice. (biomedcentral.com)

The strain is now valued as a source of embryonic stem cells for making knockout mice. (jax.org)

Pathobiology of aging mice and GEM: background strains and experimental design. (jax.org)

Results suggest that white-tailed deer harbor a variant strain not associated with human infection, but contrary to published reports, white-tailed deer are not a reservoir for strains that cause human disease. (cdc.gov)
These results led to the current study, which was conducted to investigate the relative potential for white-tailed deer to be a reservoir for AP-ha, AP-Variant 1, or both strains. (cdc.gov)
We examined blood samples from white-tailed deer to determine the strains of A. phagocytophilum with which these deer were infected and the ticks feeding on these deer to identify strains to which they were exposed. (cdc.gov)

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