• After adjusting for several potential confounders such as age, smoking, and body fatness variables, the low and moderate CRF groups had odds of 4.64 (95% CI, 2.00 to 10.79) and 2.57 (95% CI, 1.04 to 6.34) for having metabolic syndrome than the high CRF group. (nature.com)
  • In the XENDOS trial, 40% of patients were classified as having metabolic syndrome based on criteria from the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP III). (medscape.com)
  • However, the consumers still associate dietary FA with fat deposition and increased occurrence of metabolic diseases such as obesity and atherosclerosis. (nature.com)
  • The current epidemic of dementia is driven, at least in part, by the concurrent epidemics of obesity, insulin resistance, T2D, and metabolic syndrome. (nih.gov)
  • Metabolic syndrome was defined with the National Cholesterol Education Program Adult Treatment Panel III criteria and a modified cut-off value of waist circumference from the Asia-Pacific Perspective: Redefining Obesity and its Treatment. (nature.com)
  • Indeed, nowadays psoriasis is considered a systemic pathology, including also other conditions, from psoriatic arthritis to obesity and metabolic disease (MetS), which increased cardiovascular risk in psoriatic patients [ 2 - 4 ]. (springer.com)
  • The name Metabolic Syndrome X was created by Dr. Gerald M Reaven when he was describing how insulin resistance leads to serious health problems like obesity, hypertension, and coronary heart disease. (naturalnews.com)
  • The current subgroup analysis of the study, presented last week at the 12th European Congress on Obesity in Helsinki, Finland, focused on those patients in XENDOS with metabolic syndrome. (medscape.com)
  • But obesity is more common in the lower socioeconomic strata, making it even more important that these drugs are reimbursed," he said, adding that Sweden has this week allowed reimbursement for orlistat again, after it was withdrawn from reimbursement several years ago. (medscape.com)
  • Methods: Metabolic syndrome is ≥3 of the following: hypertriglyceridemia, low high-density lipoprotein (HDL) cholesterol, hypertension, abdominal obesity, and high serum glucose. (natap.org)
  • In particular, we wanted to identify those important to maintaining the framework of fat tissue, called the extracellular matrix, which becomes dysfunctional in obesity," said first author Dr. David Bradley, assistant professor in the Division of Endocrinology, Diabetes and Metabolism at The Ohio State University Wexner Medical Center and a member of Ohio State's Diabetes and Metabolism Research Center. (medicalxpress.com)
  • Insulin resistance is a major cause of Type 2 Diabetes, and patients with obesity commonly have both metabolic and cardiovascular complications. (medicalxpress.com)
  • Physician and obesity medicine specialist Dr. Naomi Parrella joins Chris in this episode of Revolution Health Radio to discuss metabolic health and how it relates to weight loss. (chriskresser.com)
  • We're going to talk about Naomi's experience in the multiple weight loss clinics [that] she runs, the difference between overweight, obesity, and metabolic health, and where those overlap, what some of the difficulties that she has faced in the clinical setting are, what some of the biggest obstacles to weight loss are, from her experience, and how to address some of those obstacles. (chriskresser.com)
  • Obesity is an important potential cause of metabolic syndrome. (stroke.org)
  • But, the reasons abdominal obesity and metabolic syndrome seem to be linked are complex and not fully understood. (stroke.org)
  • By using such a creature, and observing the growth of fat after injections of different kinds of immature cells, Rockefeller University scientists have discovered an important fat precursor cell that may in time explain how changes in the numbers of fat cells might increase and lead to obesity. (news-medical.net)
  • The findings are central to understanding chronic diseases, such as obesity and diabetes, as fat cells produce hormones critical for metabolic control, the researchers said. (news-medical.net)
  • Metabolic syndrome is an asymptomatic pathophysiological condition characterized by high blood pressure, central obesity, insulin resistance, dyslipidaemia and hyperglycaemia (1). (who.int)
  • If the current trend in obesity and type 2 diabetes continues unchanged, the incidence of metabolic syndrome will be expected to increase, especially in developing countries (2,6). (who.int)
  • Factors, such as socioeconomic status, lack of physical activity, smoking, family history of diabetes, obesity and the western lifestyle, increase the risk of metabolic syndrome (8). (who.int)
  • New research demonstrates that obesity does not always go hand in hand with metabolic changes in the body that can lead to diabetes, heart disease and stroke. (biospace.com)
  • In a study at Washington University School of Medicine in St. Louis, researchers found that a subset of obese people do not have common metabolic abnormalities associated with obesity, such as insulin resistance, abnormal blood lipids (high triglycerides and low HDL cholesterol), high blood pressure and excess liver fat. (biospace.com)
  • It's important to point out that once the study was completed, we enrolled all subjects in our weight-loss program to make sure they lost all of the weight they had gained, or more," said Klein, who also directs the Division of Geriatrics and Nutritional Science and the Atkins Center of Excellence in Obesity Medicine. (biospace.com)
  • These results suggest that the ability of body fat to expand and increase in a healthy way may protect some people from the metabolic problems associated with obesity and weight gain," said Klein. (biospace.com)
  • Some people with a metabolic myopathy never develop symptoms due to the body's ability to produce enough ATP through alternative pathways (e.g. the majority of those with AMP-deaminase deficiency are asymptomatic). (wikipedia.org)
  • The symptoms experienced also depend on which metabolic pathway is impaired, as different metabolic pathways produce ATP at different time periods during activity and rest, as well as the type of activity (anerobic or aerobic) and its intensity (level of ATP consumption). (wikipedia.org)
  • For instance, isotope-assisted metabolomics technology has enabled the mapping of a global metabolic network, estimation of flux at branch points of metabolic pathways, and assignment of elemental formulas to unknown metabolites. (mdpi.com)
  • In biochemistry, metabolic pathways are series of chemical reactions occurring within a cell. (conceptdraw.com)
  • Because of the many chemicals (a.k.a. "metabolites") that may be involved, metabolic pathways can be quite elaborate. (conceptdraw.com)
  • This collection of pathways is called the metabolic network. (conceptdraw.com)
  • Pathways are important to the maintenance of homeostasis within an organism. (conceptdraw.com)
  • The vector stencils library " Biochemistry of metabolism" contains 46 metabolite symbols for drawing metabolic pathways maps, biochemical diagrams and metabolism process flow charts using the ConceptDraw PRO diagramming and vector drawing software. (conceptdraw.com)
  • Mass spectrometry-based metabolomics was used to investigate the overall metabolic changes and relevant toxicological pathways. (databasefootball.com)
  • Schematic overview of the disturbed metabolic pathways in BEAS-2B cells upon PM2.5 exposure. (databasefootball.com)
  • Transcriptional regulation of the genes in metabolic pathways is a highly successful strategy, which is virtually universal in microorganisms. (lu.se)
  • When a second nutrient and its metabolic pathway are introduced, the system must further decide whether and how to activate both pathways. (lu.se)
  • Citation: Troein C, Ahre´n D, Krogh M, Peterson C (2007) Is Transcriptional Regulation of Metabolic Pathways an Optimal Strategy for Fitness? (lu.se)
  • A number of studies have explored how regulation of generally, and at least to a first approximation, it is obvious that metabolic pathways affects the growth rate of microorganisms, gene regulation only is useful if the environmental conditions vary both in the steady state and in response to changes in the local with time. (lu.se)
  • Metabolic disorders typically result when an enzyme necessary for some step in a metabolic process is missing or improperly constructed due to a genetic defect. (newworldencyclopedia.org)
  • Given the number of metabolic disorders and the range of systems affected, these disorders are manifested in a wide array of symptoms of varying severity, ranging from recurrent vomiting, lethargy, and muscle weakness, to liver and heart failure, developmental delay, and mental retardation. (newworldencyclopedia.org)
  • Most metabolic disorders are inherited from one or both parents who carry a defective gene that regulates a particular protein in a class of the body's cells. (newworldencyclopedia.org)
  • Metabolic disorders are diseases that impact the body's ability to metabolise specific nutrients or enzymes. (bellyfatlossguru.com)
  • In addition, the function of the cell to complete necessary biochemical reactions involving the synthesis of proteins, carbohydrates and lipids is also affected by metabolic disorders. (bellyfatlossguru.com)
  • The shell protects the tortoise from its predators, like your metabolic health protects you from metabolic disorders like diabetes. (bellyfatlossguru.com)
  • More than a decade of work conducted by UT Southwestern Medical Center at Dallas researchers has led to a better understanding of the underlying causes of lipodystrophies - disorders characterized by the selective loss of fat tissues, resulting in metabolic complications, such as severe diabetes and high blood cholesterol levels. (news-medical.net)
  • It's important to note that without the weight gain and antipsychotic use factors, there does not seem to be a connection between metabolic syndrome and psychiatric disorders in general. (healthyplace.com)
  • Biochemical genetic testing and newborn screening are essential laboratory services for the screening, detection, diagnosis, and monitoring of inborn errors of metabolism or inherited metabolic disorders. (cdc.gov)
  • These recommendations are intended for laboratories that perform biochemical genetic testing to improve the quality of laboratory services and for newborn screening laboratories to ensure the quality of laboratory practices for inherited metabolic disorders. (cdc.gov)
  • Metabolic disorders are important because they affect energy production or damage tissues. (merckvetmanual.com)
  • Acquired metabolic disorders are more common and significant. (merckvetmanual.com)
  • Metabolic storage disorders usually result from the body's inability to break down some substance because of partial or complete lack of a certain enzyme. (merckvetmanual.com)
  • Metabolic storage disorders can be either genetic or acquired. (merckvetmanual.com)
  • Some metabolic disorders are caused by an increased demand for a specific element or nutrient that has become deficient under certain conditions. (merckvetmanual.com)
  • It's important to learn about proper meal-planning when your child has diabetes. (uhhospitals.org)
  • A basic metabolic panel may be part of a routine checkup and also may be used to diagnose certain medical issues, including diabetes and kidney or lung problems. (healthline.com)
  • Metabolic syndrome is a name for a group of risk factors that occur together and increase the chance of having coronary artery disease , stroke , and type 2 diabetes . (medlineplus.gov)
  • Many people with metabolic syndrome used to be told they had pre-diabetes, early hypertension (high blood pressure) or mild hyperlipidemia (high fats in the blood). (medlineplus.gov)
  • People with metabolic syndrome have an increased long-term risk of developing heart disease, type 2 diabetes, stroke, kidney disease, and poor blood supply to the legs. (medlineplus.gov)
  • Irregular sleep schedules, including highly variable bedtimes and staying up much later than usual, are associated in midlife women with insulin resistance, which is an important indicator of metabolic health, including diabetes risk," said senior author Martica Hall, PhD, professor of psychiatry at the University of Pittsburgh. (sciencedaily.com)
  • The results are important because diabetes risk increases in midlife women," said Hall. (sciencedaily.com)
  • Metabolic control is an important factor in growth of children with type I diabetes. (hindawi.com)
  • Metabolic control was not the only predictive factor of physical growth in children with diabetes. (hindawi.com)
  • Diabetes mellitus (DM) is a common chronic metabolic disorder and a main problem in health systems [ 2 ] with two main types: type I, in which the secretion of insulin from the beta cells is reduced or absent, and type II, which shows decreased insulin or insulin resistance in skeletal muscle, liver, and adipose tissue [ 3 - 6 ]. (hindawi.com)
  • However others have reported that children with diabetes were shorter in height at diagnosis compared to healthy children [ 22 , 23 ], in which the age of diagnosis has apparently been the most important factor affecting the results of these studies [ 20 ]. (hindawi.com)
  • The aim of this study was to determine the relationship of metabolic control and growth in children with DM referred to Golestan Hospital diabetes clinic in Ahvaz, southwest of Iran, and the prevalence of growth retardation in such children. (hindawi.com)
  • Helsinki, Finland - The antiobesity drug orlistat (Xenical ® , Roche) improved cardiovascular risk factors and prevented the development of type 2 diabetes in patients with metabolic syndrome , according to a new analysis of the XENDOS study. (medscape.com)
  • Cite this: Orlistat prevents diabetes in metabolic syndrome patients - Medscape - Jun 04, 2003. (medscape.com)
  • Metabolic syndrome is a cluster of conditions including high blood pressure, high blood sugar, excess body fat, and abnormal cholesterol levels that lead to an increased risk of heart disease, diabetes and stroke. (otago.ac.nz)
  • The symptoms of metabolic syndrome in themselves will disturb metabolic functioning and make your body vulnerable to metabolic diseases like diabetes, mitochondrial dysfunction, and Gaucher's disease, to name a few. (bellyfatlossguru.com)
  • Background: Metabolic syndrome increases the risk of cardiovascular outcomes and type II diabetes. (natap.org)
  • Metabolic syndrome is a group of conditions that make it more likely you'll have heart disease, a stroke, or diabetes. (uvahealth.com)
  • Metabolic syndrome defined and discover why people with schizophrenia and bipolar disorder are at highest risk for developing metabolic syndrome and diabetes. (healthyplace.com)
  • In fact, it's not possible to talk about diabetes and mental health without mentioning metabolic syndrome as they are intricately connected. (healthyplace.com)
  • Metabolic Syndrome is a group of risk factors present in a single individual that promote the development of coronary artery disease, stroke, and type 2 diabetes. (healthyplace.com)
  • Those with metabolic syndrome are at risk of serious health problems including heart attack, stroke, and diabetes. (healthyplace.com)
  • Which Mental Illnesses Are Associated with Metabolic Syndrome and Diabetes? (healthyplace.com)
  • Research has shown children who watched a lot of television were more likely to have metabolic syndrome as an adult. (otago.ac.nz)
  • Torgerson believes all obese patients should be screened for metabolic syndrome so that they can be more intensively treated to prevent the development of cardiovascular complications. (medscape.com)
  • This observation is important clinically because about 25 percent of obese people do not have metabolic complications," he added. (biospace.com)
  • Previous studies already demonstrated that some fatty acids are linked with inflammatory response, preventing metabolic diseases. (nature.com)
  • To better understand the role of dietary FA on metabolic diseases, for the first time, a study to identify key transcription factors (TF) involved in lipid metabolism and inflammatory response by transcriptome analysis from liver samples of animal models was performed. (nature.com)
  • NewsTarget) Metabolic Syndrome X may be one of the most common and overlooked diseases to strike Americans. (naturalnews.com)
  • When your metabolic processes are in flow, there is little risk of developing diseases that might hinder your overall health. (bellyfatlossguru.com)
  • Metabolic health, simply put, is the absence of metabolic diseases. (bellyfatlossguru.com)
  • It prevents you from the risk of metabolic diseases and improves your quality of life. (bellyfatlossguru.com)
  • Metabolic syndrome is a set of conditions that raise the risk of cardiovascular diseases and other ailments. (bellyfatlossguru.com)
  • As the number of inherited metabolic diseases that are included in state-based newborn screening programs continues to increase, ensuring the quality of performance and delivery of testing services remains a continuous challenge not only for public health laboratories and other newborn screening facilities but also for biochemical genetic testing laboratories. (cdc.gov)
  • The recommended practices address the benefits of using a quality management system approach, factors to consider before introducing new tests, establishment and verification of test performance specifications, the total laboratory testing process (which consists of the preanalytic, analytic, and postanalytic phases), confidentiality of patient information and test results, and personnel qualifications and responsibilities for laboratory testing for inherited metabolic diseases. (cdc.gov)
  • Genetic (inherited) storage diseases are named according to the specific metabolic byproduct that builds up in the body. (merckvetmanual.com)
  • The difference between production-related metabolic diseases and nutritional deficiencies is often subtle. (merckvetmanual.com)
  • Consumption of vegetables and fruit, the amount and quality of fat ingested, and the intake of salt are the most important elements of a diet for prevention of both cardiovascular diseases and cancers. (who.int)
  • Group analyses showed significant and inverse dose-response trends between the metabolic syndrome markers and CRF levels such that men with high and moderate CRF levels had more favorable profiles in body fatness, resting blood pressures, mean values in fasting lipids, glucose, and insulin, and homeostasis model of assessment-insulin resistance than men with low CRF level. (nature.com)
  • Also known as Syndrome X or insulin-resistance syndrome, metabolic syndrome is defined as having three or more risk factors, such as high waist measurement, increased fasting glucose levels, abnormal blood lipid levels, or high blood pressure, in a single patient, leading to an increased risk of cardiovascular disease. (medscape.com)
  • Metabolic syndrome is closely associated with a generalized metabolic disorder called insulin resistance. (stroke.org)
  • Before and after weight gain, the researchers carefully evaluated each study subject's body composition, insulin sensitivity and ability to regulate blood sugar, liver fat and other measures of metabolic health. (biospace.com)
  • A metabolic disorder is any disease or disorder that negatively affects the biochemical reactions through which individual animal cells process nutrient molecules (such as the components of carbohydrates , proteins , and fats ) to yield energy or perform the functions necessary to sustain life (such as building complex molecules and creating cellular structure). (newworldencyclopedia.org)
  • The biological indices determination also showed that oxidative stress and inflammation played important roles in energy metabolism disorder. (databasefootball.com)
  • Due to treatment with certain high-risk antipsychotic medications , those with schizophrenia are at the highest risk of developing the risk factors associated with metabolic syndrome, closely followed by those with bipolar disorder . (healthyplace.com)
  • Even having one of the risk factors of metabolic syndrome, such as high blood sugar, isn't healthy, but when a person has combined risk factors such as high blood sugar and high cholesterol, this is a set up for very serious health problems- especially when a person has the added burden of a psychiatric disorder. (healthyplace.com)
  • Whenever the function of an enzyme is affected, a metabolic disorder can develop. (merckvetmanual.com)
  • By using data from a 2015 clinical trial on Ebola convalescent-phase plasma in Guinea, we assessed the prevalence of electrolyte and metabolic abnormalities at admission and their predictive value to stratify patients into risk groups. (cdc.gov)
  • Most of the metabolic abnormalities defining metabolic syndrome are observed in HIV. (natap.org)
  • Capitalizing on the existing expertise in reconstruction of carnosic acid in yeast, I applied an interdisciplinary approach that involve metabolic engineering, lipid biochemistry and biophysics to study the role of membrane lipid composition on the CYPs activity and the assembly of the metabolic complex involved in this pathway. (europa.eu)
  • Metabolic myopathies are myopathies that result from defects in biochemical metabolism that primarily affect muscle. (wikipedia.org)
  • The biochemical diagram example "Metabolic pathway map" was created using the ConceptDraw PRO diagramming and vector drawing software extended with the Biology solution from the Science and Education area of ConceptDraw Solution Park. (conceptdraw.com)
  • The vector stencils library "Citric acid cycle (TCA cycle)" contains 26 symbols of metabolites for drawing metabolic pathway maps and biochemical shematic diagrams of the citric acid cycle (TCA cycle, tricarboxylic acid cycle, Krebs cycle) and diagrams of metabolism processes. (conceptdraw.com)
  • The research described here also help address basic scientific questions on the molecular regulation and biochemical understanding of the role of membrane composition on functionality of membrane-associated proteins of plant origin that may be involved in formation of yet questionable metabolic complexes or metabolons. (europa.eu)
  • Early research sought to elucidate the cause(s) for the apparent role of metabolic dysfunction in the increased prevalence of neurocognitive dysfunction and dementia, tentatively attributed to vascular contributions to cognitive impairment and dementia (VCID) and Alzheimer's disease (AD). (nih.gov)
  • In summary, the PM 2.5 exposure caused the metabolic reprogramming and mitochondrial dysfunction by perturbing purine metabolism, arginine and proline metabolism, glutathione metabolism, TCA cycle, and glycolysis caused by oxidative stress and inflammation. (databasefootball.com)
  • Conclusions: Low-dose CO poisoning is associated with early mitochondrial disruption prior to an observable phenotype highlighting the important role of mitochondrial function in the pathology of CO poisoning. (lu.se)
  • Objective: To determine the incidence and risk factors for metabolic syndrome in HIV-infected adults in the Nutrition for Healthy Living (NFHL) study (2000-2003) and prevalence relative to the findings of the National Health and Nutrition Examination Survey (NHANES) (1999-2002). (natap.org)
  • The baseline prevalence of metabolic syndrome in the NFHL study (n = 477) was compared to that in the NHANES (n = 1876), adjusted for age, race, gender, poverty, exercise, and diet. (natap.org)
  • The prevalence of metabolic syndrome was significantly lower in HAART and non-HAART users compared with NHANES participants unadjusted for body mass index (BMI). (natap.org)
  • To our knowledge, this is one of the first large studies of the incidence and prevalence of metabolic syndrome in HIV. (natap.org)
  • At the cellular level, metabolic myopathies lack some kind of enzyme or transport protein that prevents the chemical reactions necessary to create adenosine triphosphate (ATP). (wikipedia.org)
  • The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions. (conceptdraw.com)
  • The name of this metabolic pathway is derived from citric acid (a type of tricarboxylic acid) that is consumed and then regenerated by this sequence of reactions to complete the cycle. (conceptdraw.com)
  • 02. Illustrate how enzymes are able to facilitate metabolic reactions, and how they are regulated. (edu.au)
  • For example, protein is broken down into amino acids, which are used in several metabolic reactions. (merckvetmanual.com)
  • There's also a condition called metabolic acidosis which occurs when your blood or fluids become overly acidic. (healthline.com)
  • Metabolic acidosis is a clinical disturbance characterized by an increase in plasma acidity. (medscape.com)
  • Metabolic acidosis should be considered a sign of an underlying disease process. (medscape.com)
  • Go to Pediatric Metabolic Acidosis and Emergent Management of Metabolic Acidosis for complete information on those topics. (medscape.com)
  • The growth process was studied in patients who were divided into 3 groups according to their HbA1C amounts, consisting of good, intermediate, and poor metabolic control. (hindawi.com)
  • Poor metabolic control can decrease height growth but has minimal influence on weight. (hindawi.com)
  • The first and foremost sign of poor metabolic health is unhealthy body weight. (bellyfatlossguru.com)
  • At the root of this lies poor metabolic health. (bellyfatlossguru.com)
  • Several different underlying conditions can cause metabolic alkalosis. (healthline.com)
  • Although ddI use has not been shown to cause metabolic changes, the increased risk of metabolic syndrome among our ddI users may reflect the effect of previous treatments on individuals or may be related to greater disease severity. (natap.org)
  • Strains of laboratory mice that are inbred for higher metabolic rates show stronger immune responses to immune challenge with stronger antigen-specific IgM production than strains bred for lower metabolic rates. (cdc.gov)
  • Frequent shifts in sleep timing may be related to adverse metabolic health among non-shift working, midlife women, new research shows. (sciencedaily.com)
  • This research demonstrates that some obese people are protected from the adverse metabolic effects of moderate weight gain, whereas others are predisposed to develop these problems," said senior investigator Samuel Klein, MD, the Danforth Professor of Medicine and Nutritional Science and director of Washington University's Center for Human Nutrition. (biospace.com)
  • We were therefore curious to explore if there is a metabolic basis for the sensitivity of 11;14 MM to ABT-199 in order to a) identify predictors of ABT-199 response and b) identify metabolic targets that could be inhibited to sensitize resistant MM to ABT-199. (lls.org)
  • This study aims to identify metabolic, clinical, and microbiota differences between small and larger dogs. (hindawi.com)
  • With the advances of magnetic resonance technology, the CBF, oxygen extraction fraction, and cerebral metabolic rate of oxygen can be measured in MRI. (ajnr.org)
  • Our aim was to measure the CBF, oxygen extraction fraction, and cerebral metabolic rate of oxygen use in patients with different severities of middle cerebral artery stenosis or acute stroke by using the arterial spin-labeling and susceptibility-weighted imaging techniques. (ajnr.org)
  • Arterial spin-labeling and SWI sequences were used to acquire CBF, oxygen extraction fraction, and cerebral metabolic rate of oxygen. (ajnr.org)
  • Hemispheres with occluded MCA (group 3) or acute stroke (group 4) had a significantly lower CBF and cerebral metabolic rate of oxygen and a significantly higher oxygen extraction fraction than the contralateral hemisphere. (ajnr.org)
  • When this offset a decrease in CBF, the cerebral metabolic rate of oxygen remained at a normal level. (ajnr.org)
  • An occluded MCA led to reduction in both the CBF and cerebral metabolic rate of oxygen. (ajnr.org)
  • Moreover, the oxygen extraction fraction and cerebral metabolic rate of oxygen significantly increased and decreased, respectively, in the occluded MCA region during acute stroke. (ajnr.org)
  • It is possible to use both parameters and the arterial oxygen content to derive cerebral metabolic rate of oxygen (CMRO 2 ) use, which is of critical importance in the occurrence of stroke. (ajnr.org)
  • Cerebral microdialysis was performed to obtain semi real time measurements of cerebral metabolic status. (lu.se)
  • To better understand these differences, we identified modules of highly cooccurring metabolites and further analyzed correlations between metabolic and clinical data. (hindawi.com)
  • Metabolic syndrome is easier to pick up as it is covered by raised lipid levels, which are generally measured in obese patients. (medscape.com)
  • In addition, obese people who didn't have these metabolic problems when the study began did not develop them even after they gained more weight. (biospace.com)
  • The study involved 20 obese participants who were asked to gain about 15 pounds over several months to determine how the extra pounds affected their metabolic functions. (biospace.com)
  • After gaining weight, the metabolic profiles of obese subjects remained normal if they were in the normal range when the study began. (biospace.com)
  • But the metabolic profiles significantly worsened after weight gain in obese subjects whose metabolic profiles already were abnormal when the study got underway. (biospace.com)
  • The intricate coordination of systems in the human body is seen in the process, catalyzed by enzymes , by which phenylalanine is degraded into tyrosine, which in turn is converted into the vitally important neurotransmitters and hormones dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline). (newworldencyclopedia.org)
  • Enzymes made by the body are needed for many metabolic processes to occur. (merckvetmanual.com)
  • Enzymes involved in metabolic processes were considered. (cdc.gov)
  • Hepatic microsomal monooxygenase systems are the most important enzymes involved in the metabolism of xenobiotics. (cdc.gov)
  • A basic metabolic panel tests levels of eight substances in the blood, which measure electrolyte balance, sugar metabolism, and kidney function. (healthline.com)
  • Metabolic myopathies are generally caused by an inherited genetic mutation, an inborn error of metabolism. (wikipedia.org)
  • Furthermore, some data processing tools have been developed to apply these techniques to a non-targeted approach, which plays an important role in revealing unknown or unexpected metabolism. (mdpi.com)
  • AMPK Metabolic Activator by Life Extension is a dietary supplement designed to revitalize cell metabolism and fight unwanted deposits of abdominal fat. (blueskyvitamin.com)
  • This article would help you understand the meaning of metabolic health and inform you of signs of a not so great metabolism. (bellyfatlossguru.com)
  • When a bat is confronted by a viral antigen, the proportional increase in metabolism for raising an immune response may be trivial compared to the very large increase in the metabolic costs of flight. (cdc.gov)
  • A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. (conceptdraw.com)
  • Foods, liquids, and drugs all generally undergo metabolic processes within the body. (merckvetmanual.com)
  • Others have Equine Metabolic Syndrome (EMS), a genetic disposition to gain weight, even with appropriate feedings. (cornell.edu)
  • Significant genetic and metabolic variation occurs within the Canis lupus species that spans from the wolf through all domesticated canines. (hindawi.com)
  • This study aimed to determine the incidence of metabolic syndrome and its predicting factors in Zahedan city. (who.int)
  • Therefore, we aimed to determine the incidence and predictors of metabolic syndrome in Zahedan city (Sistan and Baluchestan province), south-eastern Islamic Republic of Iran. (who.int)
  • Metabolic syndrome is mostly diagnosed through low HDL and high triglycerides in HIV. (natap.org)
  • Specific antiretroviral therapies are known to affect individual components of the metabolic syndrome adversely, such as increasing triglycerides (lopinavir/ritonavir,32 nevirapine,33 and nelfinavir33) and increasing fasting glucose (indinavir34 and lopinavir/ritonavir35). (natap.org)
  • Although some people are genetically prone to developing metabolic syndrome, others develop it as result of their lifestyle or other circumstances that lead to the five risk factors: high blood glucose (sugar), low levels of HDL ("good") cholesterol in the blood, high levels of triglycerides in the blood, large waist circumference or "apple-shaped" body and high blood pressure . (stroke.org)
  • We know from the metabolic syndrome that HDL and triglyceride are key indicators of risk from heart disease and stroke. (sages.org)
  • Conclusion: These findings suggest that low CRF is a significant and independent risk factor for metabolic syndrome in young Korean men. (nature.com)
  • This information is important either for Dermatologists and Nutritionists to increases the knowledge on the possible bi-directional relationships between low vitamin D status and psoriasis and on the potential usefulness of vitamin D in psoriasis with the aim not only to reduce its clinical severity, but also for delineating the risk profile for co-morbidities cardiac risk factors that may result from psoriasis. (springer.com)
  • A dose-response relation was found between exposure to work stressors over 14 years and risk of the metabolic syndrome, independent of other relevant risk factors. (nih.gov)
  • Stress at work is an important risk factor for the metabolic syndrome. (nih.gov)
  • Co-principal investigator of the study, Dr Jarl Torgerson (Sahlgrenska University Hospital, Göteborg, Sweden) commented to heart wire that metabolic syndrome patients represent a high-risk group that need to be identified and treated. (medscape.com)
  • Those who watched the most had a higher risk of metabolic syndrome in adulthood," Professor Hancox says. (otago.ac.nz)
  • Our results suggest that HIV itself, treatment, and host factors affect the risk of metabolic syndrome in HIV disease. (natap.org)
  • Among our cohort of HIV-infected adults, the risk of developing metabolic syndrome was higher in those with a clinically relevant increase in viral load (≥0.5 log) in the previous 6 months. (natap.org)
  • Other therapies have been associated with improvements in metabolic profiles, such as increases in HDL cholesterol (nevirapine and nelfinavir).33 In our cohort, lopinavir/ritonavir users had a higher risk of developing metabolic syndrome. (natap.org)
  • Who's at risk for metabolic syndrome? (stroke.org)
  • Risk for metabolic syndrome increases with age. (stroke.org)
  • When you experience the risk factors associated with metabolic syndrome, it doubles your risk of blood vessel and heart disease, which can lead to heart attacks and strokes. (healthyplace.com)
  • Most studies on the incidence and risk factors of metabolic syndrome have been conducted in developed countries or regions where the populations have a relatively high socioeconomic status. (who.int)
  • However, it can be difficult to ascertain the role of virus-specific factors, as additional factors such as age and the time between infections, has also been shown to play an important role in the risk for severe disease. (cdc.gov)
  • However, with stress and irregular lifestyles being the order of the day, metabolic syndrome is no longer limited to older adults. (bellyfatlossguru.com)
  • This is especially important for patients with metabolic syndrome. (sages.org)
  • A majority of patients with metabolic myopathies have dynamic rather than static findings, typically experiencing exercise intolerance, muscle pain, and cramps with exercise rather than fixed muscle weakness. (wikipedia.org)
  • This morning workshop will present important statistics and resources for you and your patients. (constantcontact.com)
  • As in the whole trial, orlistat was also associated with more weight loss, a greater reduction in waist measurement, greater reductions in blood pressure, and improvements in lipid levels compared with diet alone in the metabolic syndrome patients. (medscape.com)
  • He estimates that about one third of patients with metabolic syndrome also have impaired glucose tolerance. (medscape.com)
  • But he says that it is even more important to detect the patients with impaired glucose tolerance. (medscape.com)
  • HIV patients are generally prescribed ddI after they have failed other antiretroviral medications because of metabolic side effects, other toxicities, or uncontrolled viral load. (natap.org)
  • Low-dose growth hormone treatment reduced abdominal fat deposits and improved blood pressure and triglyceride levels in a group of patients with HIV lipodystrophy, a condition involving the redistribution of fat and other metabolic changes in patients receiving combination drug therapy for HIV infection. (news-medical.net)
  • Use of an oral antidiabetes medication produced significant improvement in a group of patients with HIV lipodsytrophy, a syndrome involving the redistribution of fat and other metabolic changes in those receiving combination drug therapy for HIV infection. (news-medical.net)
  • When the external environment changed, cells may rewrite the energy metabolic phenotype to adapt to the new circumstances and suppress damage. (databasefootball.com)
  • In this study, we found that exposure to PM 2.5 could change energy metabolic phenotype from more effective oxidative phosphorylation to less-effective glycolysis. (databasefootball.com)
  • Late onset of a metabolic disease is often triggered by acute metabolic stresses, such as infection, fasting, or consumption of a nutrient for which a metabolic intolerance exists. (newworldencyclopedia.org)
  • In some cases, dietary intake of a nutrient, such as calcium, is rapidly used up for an ongoing, high metabolic need, such as lactation (or nursing puppies). (merckvetmanual.com)
  • The incidence of metabolic syndrome in the NFHL study was higher with increasing viral load, higher BMI, higher trunk-to-limb fat ratio, and Kaletra (lopinavir/ritonavir) or didanosine (ddI) use and lower among college-educated persons. (natap.org)
  • Age-standardized incidence of metabolic syndrome was calculated and its predictors were evaluated in a logistic regression analysis. (who.int)
  • The incidence of metabolic syndrome varied from 17.21% to 27.18% depending on the criteria used and it was higher in women. (who.int)
  • The incidence of metabolic syndrome has increased in Zahedan. (who.int)
  • Aliab H. Incidence of and factors associated with metabolic syndrome, south-east Islamic Republic of Iran. (who.int)
  • The incidence of metabolic syndrome has been reported to range from 28 persons per 1000 persons-year to more than 70 per 1000 persons-year in different regions of the world (4,5). (who.int)
  • According to epidemiological studies, the incidence of metabolic syndrome is higher in women than men (5,7). (who.int)
  • Metabolic alkalosis is a condition that occurs when your blood becomes overly alkaline. (healthline.com)
  • The authors suggest that future studies of sleep timing and metabolic health should examine potential mechanisms including melatonin as well as other hormones that are relevant to metabolic health and sensitive to circadian misalignment, including leptin, ghrelin and cortisol. (sciencedaily.com)
  • Catecholamine are important as neurotransmitters and hormones . (newworldencyclopedia.org)
  • metabolic changes, such as those in steroid hormones and growth factors. (who.int)
  • Many people don't experience any symptoms of metabolic alkalosis, so you may not know that you have it. (healthline.com)
  • Metabolic alkalosis may not show any symptoms. (healthline.com)
  • Biological measures of the metabolic syndrome, based on the National Cholesterol Education Program definition, measured in 1997-9. (nih.gov)
  • In contrast, the relation between increasing viral load and metabolic syndrome does not seem to be mediated by general inflammation caused by chronic infection for 2 reasons. (natap.org)
  • Helping people effectively lose weight and keep it off is still one of the most important things we can do to prevent and reverse chronic disease and extend life span. (chriskresser.com)
  • Two organs help to compensate for metabolic alkalosis - our lungs and our kidneys. (healthline.com)
  • All participants without metabolic syndrome in a 2009 study in Zahedan, available in 2017, were included in this study. (who.int)
  • First, high viral load did not predict development of metabolic syndrome. (natap.org)
  • These changes were consistent with the need for DNA damage repair because of high metabolic rates during flight. (cdc.gov)
  • Fever in mammals is accompanied by an initially high metabolic rate associated with beneficial immune responses. (cdc.gov)
  • During flight, bats exhibit a high increase in metabolic rate over the resting metabolic rate of normeothermic, otherwise active bats. (cdc.gov)
  • Metabolic myopathies are categorized by the metabolic pathway to which the deficient enzyme or transport protein belongs. (wikipedia.org)
  • The key ingredient found in AMPK Metabolic Activator by Life Extension is the enzyme AMPK, found in every cell in the body. (blueskyvitamin.com)
  • Alpha-lipoic acid is effective for deactivating free radicals and is important for converting glucose to energy. (naturalnews.com)
  • Glycolysis is the metabolic pathway that converts glucose into pyruvate. (conceptdraw.com)
  • For example, in hypoglycemia , the animal's metabolic reserves are unable to sustain sugar (or glucose) in the blood at a level needed for normal function. (merckvetmanual.com)
  • Metabolic alkalosis usually results from severe vomiting or a potassium or chloride deficiency. (healthline.com)
  • This study emphasizes the important health benefits of keeping a regular sleep schedule," said American Academy of Sleep Medicine President Dr. Nathaniel Watson, who was not involved in the study. (sciencedaily.com)
  • Metabolic health was better in women who had more regular sleep schedules, including regular bedtimes across weekdays and weekends. (sciencedaily.com)
  • What is Metabolic Health, and Why is it Important? (bellyfatlossguru.com)
  • You will also learn how you could improve your metabolic health and benefit from it. (bellyfatlossguru.com)
  • Several factors affect your metabolic health. (bellyfatlossguru.com)
  • There is no fixed solution to improving your metabolic health as each one's metabolic health is unique to them. (bellyfatlossguru.com)
  • Your metabolic health is of utmost priority to help you maintain a sustainable life. (bellyfatlossguru.com)
  • Metabolic health is like what a shell is to a tortoise. (bellyfatlossguru.com)
  • Similarly, assessing your metabolic patterns, eating the food that benefits you, and personalised physical activity to suit you would all contribute to properly managed metabolic health. (bellyfatlossguru.com)
  • Metabolic syndrome and metabolic health have a direct correlation. (bellyfatlossguru.com)
  • All in all, this would leave your metabolic health on haywire. (bellyfatlossguru.com)
  • The distinction between 'less serious' effects and 'serious' effects is considered to be important because it helps the users of the profiles to identify levels of exposure at which major health effects start to appear. (cdc.gov)