Implications human cutaneous leishmaniasis leishmaniasis cutaneous. Medical search. Frequent questions

Both cutaneous and visceral leishmaniasis are prevalent. (who.int)
The cutaneous form of the disease is seen throughout the country, being highly endemic in Baluchistan, whereas the visceral form is prevalent in the northern part of the country [2]. (who.int)
Objective: This study aimed to investigate the association between HLA alleles and visceral leishmaniasis (VL) in a sample of Iraqi patients. (ijabbr.com)
Palumbo E. Visceral leishmaniasis in children: a review. (ijabbr.com)
Association analysis of HLAclass II and class III gene polymorphisms in the susceptibility to Mediterranean visceral leishmaniasis. (ijabbr.com)
Genetic analysis of multicase families of visceral leishmaniasis in northeastern Brazil: no major role for class II or class III regions of HLA. (ijabbr.com)
Results The barriers along the visceral leishmaniasis (VL) supply chain were identified as emerging themes, grouped across supply chain activities and health systems component(s). (bmj.com)
Hailu A, Mudawi Musa A, Royce C, Wasunna M (2005) Visceral Leishmaniasis: New Health Tools Are Needed. (plos.org)
The authors are all members of the Leishmaniasis East Africa Platform and are currently engaged in the clinical development of paromomycin for treatment of visceral leishmaniasis. (plos.org)
Visceral leishmaniasis (VL), commonly known as kala-azar, from the Hindu vernacular, is a human systemic disease caused by parasitic protozoan species of the genus Leishmania . (plos.org)
5. Quinnell RJ, Courtenay O. Transmission, reservoir hosts and control of zoonotic visceral leishmaniasis. (ac.ir)
A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH. (ac.ir)
Caged sand flies were reared from local P. duboscqi and the area has long been studied as a human cutaneous and visceral Leishmania focus. (usda.gov)
Visceral leishmaniasis (VL) is a vector-borne disease that is caused by the protozoan Leishmania infantum and transmitted to humans and other mammals through the bites of infected female sandflies. (lidsen.com)
The common forms of the disease in the old-world are cutaneous leishmaniasis (CutL), visceral leishmaniasis (VisL)[ 3 ] and post Kala-azar dermal leishmaniasis (PKDL)[ 4 ]. (biomedcentral.com)
Post-kala-azar dermal leishmaniasis (PKDL) is a dermal complication of visceral leishmaniasis (VL), which may occur after or during treatment. (biomedcentral.com)
Post-kala-azar dermal leishmaniasis (PKDL) is a rare skin disease, which may occur after treatment of visceral leishmaniasis (VL) and is encountered mainly in India and in the Sudan, where it was also reported to occur during active VL. (biomedcentral.com)
2001. Distinct immunity in visceral patients from that in both subclinically infected and in drug-cured people: implications for the mechanism of underlying drug cure. (ucalgary.ca)

Cutaneous lesions were experimentally induced by inoculation with leishmania promastigotes in 60 golden hamsters. (who.int)
The principal causative agents of leishmaniasis in Asia, Middle East, Africa and parts of Europe are Leishmania donovani, L. major, L. tropica and L. infantum [1]. (who.int)
Worldwide Distribution of Leishmania Species Pathogenic in Humans. (jamanetwork.com)
Kerr SF, McHugh CP, Dronen NO Jr. Leishmaniasis in Texas: prevalence and seasonal transmission of Leishmania mexicana in Neotoma micropus. (jamanetwork.com)
Characterization of a Leishmania isolate from the rodent host Neotoma micropus collected in Texas and comparison with human isolates. (jamanetwork.com)
Leishmaniasis is a vector-borne disease caused by an obligate intracellular protozoa of genus Leishmania and is transmitted by the bite of a female phlebotomine sand fly ( Figure 1 ). (intechopen.com)
Background: Leishmania (L.) killicki is responsible for the chronic cutaneous leishmaniasis. (lincoln.ac.uk)
Leishmaniasis is caused by protozoan Leishmania parasites that are transmitted through female sandfly bites. (ac.ir)
Climate change and increased travel and migration have contributed to the spread of leishmaniasis in Europe, which may allow the introduction of new exotic Leishmania species or change the profile of known strains. (unav.edu)
Although Leishmania infantum is the main agent responsible for this disease in humans and animals, other species and hybrids have been detected. (unav.edu)
Sand flies pose a particular threat because of their ability to vector Leishmania parasites to humans, which can cause permanent disfiguring skin lesions or extremely serious permanent organ damage. (usda.gov)
A study was carried out in different parts of Sri Lanka including cutaneous leishmaniasis prevailing localities to characterise the sibling species of Phlebotomus ( Euphlebotomus ) argentipes sensu lato and to establish their possible role in Leishmania transmission. (biomedcentral.com)
Vectorial capacity of the sibling species was checked by detecting human and Leishmania DNA. (biomedcentral.com)
The Leishmania mini-circle kinetoplastid, heat shock protein 70 (hsp70) and internal transcribed spacer I DNA along with human blood were detected from sibling species A only, which has not previously been considered to be a vector. (biomedcentral.com)
biotaneotropica.org.br/v11n1a/en/abstract?inventory+bn0361101a2011.Abstract: Phlebotomine sand flies are medically important insects, responsible for the transmission of Leishmania parasites between humans and non-human animal reservoirs, which are found throughout São Paulo State, Brazil. (scite.ai)
Sequencing results revealed two blood sources: humans (n = 4) and reptiles (n = 1) indicating possible role of Sergentomyia species in the transmission of human Leishmania. (bvsalud.org)
Further studies should focus on the role of Sergentomyia in human Leishmania transmission and possible control of this disease. (bvsalud.org)
The diagnosis of post-kala-azar dermal leishmaniasis was established because at this time there was no hepatosplenomegaly and the bone marrow did not show Leishmania parasites thus excluding VL. (biomedcentral.com)
In this research, we use dogs as sentinels for Chagas and leishmania transmission risk in humans. (gottdenkerlab.com)
Work in this laboratory is focussed on leishmaniasis, a chronic disease caused by the intracellular protozoa parasite Leishmania which affects more than 500 million people in several countries in the world. (ucalgary.ca)
Bayih AG, Daifalla NS, Gedamu L (2014) DNA-Protein Immunization Using Leishmania Peroxidoxin-1 Induces a Strong CD4+ T Cell Response and Partially Protects Mice from Cutaneous Leishmaniasis: Role of Fusion Murine Granulocyte-Macrophage Colony-Stimulating Factor DNA Adjuvant. (ucalgary.ca)
In addition, when the researchers examined samples from human Leishmania patients, they found similar patterns of dysbiosis as in the infected mice, a hint that the findings may extend to people. (agribusinessinfo.com)
Mirroring the findings in humans, the team found that infection with the Leishmania parasite induced a change in the skin microbiota in mice. (agribusinessinfo.com)
The Leishmania parasite causes several forms of the disease leishmaniasis, including cutaneous leishmaniasis, which causes skin sores. (durenrx.com)

Post-kala-azar dermal leishmaniasis is a rare dermal complication of VL that mimics leprosy and should be considered particularly in countries where both diseases are endemic. (biomedcentral.com)

During the last 2 decades, many attempts have been made to develop effective new compounds for treating cutaneous leishmaniasis (CL) that would be economical, that could be applied topically to lesions and that would avoid the development of resistance. (who.int)
Cutaneous leishmaniasis (CL) lesions are chronic and result in disfiguring scars. (infontd.org)
For primary isolation of parasites for inn for treating cutaneous leishmaniasis (CL) oculation into experimental animals a drop that would be economical, that could be of aspirate was taken from underneath a applied topically to lesions and that would cutaneous leishmaniasis lesion infected avoid the development of resistance. (who.int)
Assess for physical signs of leprosy in 3 general areas: cutaneous lesions, neuropathies, and eyes. (medscape.com)
For cutaneous lesions, assess the number and distribution of skin lesions. (medscape.com)
Human papillomavirus genotyping using next generation sequencing (NGS) in cervical lesions: Genotypes by histologic grade and their relative proportion in multiple infections. (who.int)

ABSTRACT A placebo-controlled trial compared 6% hexadecyl-phosphorylcholine (HePC) and 12% benzethonium chloride ointment with placebo ointment for treatment of cutaneous leishmaniasis. (who.int)

Leishmaniasis is a vector-borne tropical/subtropical disease caused by an intracellular parasite transmitted to humans by sand fly bite. (intechopen.com)
This is significant because the parasite may infect humans (via ingestion of infected snails or larvae released in slime trails on improperly washed vegetables like lettuce) and cause neurological symptoms from severe headaches to disease (eosinophilic meningitis) and death. (agriculture.gov.au)
a coccidian parasite usually found in the faeces of cattle, has been recently implicated as an agent of human intestinal disease, mainly in immunocompromised patients. (scielo.br)
Our goal is to hopefully understand the survival mechanism(s) of the parasite in human macrophages (a stressful environment) during infection at the molecular level and ultimately use molecular probes for diagnostic purposes as well as design vaccine(s) for future treatment of individuals infected with this parasite. (ucalgary.ca)
Cutaneous leishmaniasis is a tropical disease caused by a parasite and transmitted by the bite of a sand fly. (agribusinessinfo.com)

Maps published in 2016 and 2017 show the geographic distribution of endemic cutaneous leishmaniasis as defined by the Infectious Diseases Society of America and the American Society of Tropical Medicine and Hygiene. (jamanetwork.com)
This chapter reviews the global perspective of Leishmaniasis with increasing recognition of emerging "Atypical forms" and new surge of disease across the world mainly due to increasing conflicts in endemic areas leading to forced migration among other causes. (intechopen.com)
Leishmaniasis is spreading in Europe, especially in endemic countries such as Italy and Spain, in part due to ongoing climate change and the increase in travel and migration. (unav.edu)
Cutaneous leishmaniasis is transmitted by the bite of its vector, the female sandfly, in endemic areas of tropical Asia, Africa, and Latin America. (aao.org)
Reducing populations of phlebotomine sand flies in areas prevalent for human leishmaniases is of ongoing importance to US military operations and civilian populations in endemic regions. (usda.gov)

The effect of a two-week regimen of topical aminosidine was investigated in a randomized, double-blind, placebo-controlled trial of 251 selected Iranian patients with zoonotic cutaneous leishmaniasis. (ox.ac.uk)
For the search, we consider the Disability Adjusted Life Years (DALYs) for the human zoonotic burden and the animal zoonotic burden in monetary terms. (preprints.org)
For the analysis, we aim to convert the burden of zoonoses of all selected studies into the zoonotic Disability Adjusted Life Years (zDALYs) - including the human and animal components. (preprints.org)

WHO considers Leishmaniasis as one of the "Neglected Tropical Diseases" that continues to be prevalent despite international, national, and local efforts towards its control and elimination over the last decade. (intechopen.com)

A randomized, placebo-controlled trial of a two-week regimen of aminosidine (paromomycin) ointment for treatment of cutaneous leishmaniasis in Iran. (ox.ac.uk)

PLOS Medicine publishes research and commentary of general interest with clear implications for patient care, public policy or clinical research agendas. (plos.org)
This originates the clinical manifestations of leishmaniasis. (plos.org)
Leishmaniasis: clinical syndromes and treatment. (ac.ir)
Not for any clinical, therapeutic, or diagnostic use in humans or animals. (genetex.com)

Acanthamoeba species are protozoa (unicellular eukaryotes) that can cause an isolated infection of the human cornea as their primary disease in humans. (aao.org)

A hypopigmented macule with a raised border is often the first cutaneous lesion. (medscape.com)

In conclusion, the infection in these dogs was predominantly due to L. amazonensis, thus indicating that diagnosing of cases of canine leishmaniasis needs to be reexamined, since the causative agent identified is not restricted to L. infantum. (scite.ai)

Risk of infection in humans is, however, low with potential sources of infection being small children ingesting infected molluscs. (agriculture.gov.au)

Improved scar quality following primary and secondary healing of cutaneous wounds. (nih.gov)

Histocompatibility antigens (HLA) in Egyptians with two parasitic skin diseases (scabies and leishmaniasis). (ijabbr.com)
Simple Summary Leishmaniasis is a group of parasitic diseases that affect humans and animals. (unav.edu)

In the absence of a vaccine, drug treatment with pentavalent antimonials is still the first line of treatment for leishmaniasis in Pakistan and worldwide. (who.int)
Emerging implications of policies on malaria treatment: genetic changes in the Pfmdr-1 gene affecting susceptibility to artemether-lumefantrine and artesunate-amodiaquine in Africa. (cdc.gov)
Arencibia JM, Pastor-Flores D, Bauer AF, Schulze JO and Biondi RM: AGC protein kinases: From structural mechanism of regulation to allosteric drug development for the treatment of human diseases. (spandidos-publications.com)

Current research includes a SENACYT-funded project in collaboration with the Parasitology Department of the Gorgas Institute on the impact of forest fragmentation on the ecology of Chagas disease and cutaneous leishmaniasis in two rural communities to the west of the Panama Canal. (gottdenkerlab.com)

Leishmaniasis is transmitted by the bite of female phlebotomine sandflies. (plos.org)

Bellacosa A, Kumar CC, Di Cristofano A and Testa JR: Activation of AKT kinases in cancer: Implications for therapeutic targeting. (spandidos-publications.com)
Arcaro A and Guerreiro AS: The phosphoinositide 3-kinase pathway in human cancer: Genetic alterations and therapeutic implications. (spandidos-publications.com)

implications of contribution for development of neurological symptoms in the COVID-19 patients. (ac.ir)

Kipp EJ, Mariscal J, Armijos RX, Weigel M, Waldrup K. Genetic evidence of enzootic leishmaniasis in a stray canine and Texas mouse from sites in west and central Texas. (jamanetwork.com)

Collateral reduction of sand flies or human cases of leishmaniases during pesticide campaigns against vectors of malaria indicate that residuals like DDT can be effective. (usda.gov)

Leishmaniasis in the World Health Organization Eastern Mediterranean Region. (ijabbr.com)
It is also theoretically possible to 'eliminate' a disease in humans while the microbe remains at large, as in the case of neonatal tetanus, for which the World Health Organization (WHO) in 1989 declared a goal of global elimination by 1995. (cdc.gov)

In adults infected with the human immunodeficiency virus (HIV) and who were excreting Cryptosporidium in their stools, the frequency was 57% for IgG but only 2% for IgM. (scielo.br)
Children infected with human immunodeficiency virus had no IgM and only 14% had IgG detectable in their sera. (scielo.br)

Sixty one plants reputed to have anti-fertility activity were tested on female Sprague-Dawley rats, in order to isolate active compounds with a potential for use in human fertility regulation. (who.int)

González C, Wang O, Strutz SE, González-Salazar C, Sánchez-Cordero V, Sarkar S. Climate change and risk of leishmaniasis in north america: predictions from ecological niche models of vector and reservoir species. (jamanetwork.com)
All these challenges related to environment, disease, and vector pose major implications on WHO's leishmaniasis control and elimination plan. (intechopen.com)
Leishmaniasis is an emerging vector-borne disease in Sri Lanka. (biomedcentral.com)
50%). Sibling species A is incriminated as a vector for leishmaniasis in Sri Lanka. (biomedcentral.com)

Systems biology of vaccination for seasonal influenza in humans. (smw.ch)
Abdellahi L, Iraji F, mahmoudabadi A, hejazi S H. Vaccination in Leishmaniasis: A Review Article. (ac.ir)

While rat poisons (including those that contain anticoagulants, bromethalin, cholecalciferol, or zinc phosphide) can be deadly if ingested by humans or other animal species, RatX® rodenticides are safe for humans and non-rodent pets and outdoor wildlife. (ecoclearproducts.com)
M any important diseases of humans, domestic animals, and wildlife are pathogens that infect multiple host species. (gottdenkerlab.com)

The diagnosis of leishmaniasis was determined through parasitological examination, the indirect enzyme-linked immunosorbent assay (ELISA) and the polymerase chain reaction (PCR). (scite.ai)
After DCLS confirmed the rabies diagnosis, the Virginia Department of Health, the New Jersey Department of Health, the New York City Department of Health and Mental Hygiene, and CDC initiated human and domestic animal rabies exposure assessments associated with the entire animal shipment. (foxrothschild.com)

Immunonogenetic studies in selected human diseases. (ijabbr.com)
Objectives To understand stakeholders' perceptions of the access barriers to quality-assured diagnostics and medicines for leishmaniasis in the high-burden region of eastern Africa, and to identify key bottlenecks to improve the supply of commodities for neglected tropical diseases. (bmj.com)

Chiu C, Wrammert J, Li GM, McCausland M, Wilson PC, Ahmed R. Cross-reactive humoral responses to influenza and their implications for a universal vaccine. (smw.ch)
Hence, it seems that the key to disease control management is the introduction of an effective vaccine, particularly against its cutaneous form. (ac.ir)
However, there is still no vaccine against different types of human leishmaniasis. (ac.ir)

12. Scott P. Development and regulation of cell-mediated immunity in experimental leishmaniasis. (ac.ir)

Niche adaptation and viral transmission of human papillomaviruses from archaic hominins to modern humans. (cdc.gov)

Eight cases of feline cutaneous leishmaniasis in Texas. (jamanetwork.com)
We conclude that this twice a day two-week regimen of aminosidine was inadequate to accelerate the recovery of most cases of cutaneous leishmaniasis. (ox.ac.uk)

6. Desjeux P. Leishmaniasis public health aspects and control. (ac.ir)
Leishmaniasis is a major public health problem worldwide. (scite.ai)

The ongoing global pandemic caused by coronavirus disease 2019 (COVID-19) has once again demonstrated the significance of the Coronaviridae family in causing human disease outbreaks. (preprints.org)

2018) Valoración de un nuevo ensayo quimioluminiscente en comparación con ELISA en la detección de IgG contra el virus de la hepatitis E. Revista de la Sociedad Andaluza de Microbiología y Parasitología Clínica. (vircell.com)

The cutaneous form occasionally becomes epidemic. (who.int)

Globally, however, dogs remain the principal source for human rabies infections ( 1 ). (foxrothschild.com)

Cutaneous polyarteritis nodosa (CPN) is an uncommon form of vasculitis of the small-and medium-sized arteries in the reticular dermis and subcutaneous tissue. (annals.edu.sg)

Control of the Leishmaniasis. (ajtmh.org)
WHO Leishmaniasis Control Team. (jamanetwork.com)
This information can be used to guide implementation of a One Health approach that involves human health, animal health, environmental, and other relevant partners in developing strategies for preparedness, response, and control to current and future coronavirus disease threats. (preprints.org)
Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, Atlanta, GA 30333. (cdc.gov)

Rat infestations pose serious health risks to humans and pets. (ecoclearproducts.com)

The present work represents the more detailed study on the evolutionary history of L. killicki relative to L. tropica and the taxonomic implications. (lincoln.ac.uk)
In the study realized, by an indirect immunofluorescence technique, specific immunoglobulins (IgG and IgM) have been demonstrated in human serum against Cryptosporidium oocysts. (scielo.br)
Discussion: The study results will provide information on published studies that have accounted for the dual burden of zoonoses (both human and animal health aspects. (preprints.org)
Our study systems include Chagas disease ( Trypanosoma cruzi ) and cutaneous leishmaniasis in Panama. (gottdenkerlab.com)

We discuss the implications of these findings for future military preventive medicine activities and encourage further investigations into the merits of ULV for enhancement of force health protection. (usda.gov)

Anatomy1

Organisms15

Diseases12

Chemicals and Drugs22

Analytical, Diagnostic and Therapeutic Techniques and Equipment7

Phenomena and Processes2

Disciplines and Occupations2

Technology, Industry, Agriculture1

Named Groups1

Health Care8

Geographicals17

Visceral18

Leishmania24

Post kala azar der1

Lesions6

ABSTRACT1

Parasite5

Endemic5

Zoonotic3

Prevalent1

Paromomycin1

Clinical4

Protozoa1

Lesion1

Causative agent1

Infection1

Wounds1

Parasitic2

Treatment3

Parasitology1

Sandflies1

Therapeutic2

Patients1

Genetic1

Malaria1

World Health Organ2

Immunodeficiency2

Compounds1

Vector4

Vaccination2

Species2

Diagnosis2

Diseases2

Vaccine3

Experimental1

Viral1

Cases2

Public Health2

20191

20181

Epidemic1

Rabies1

Form1

Control4

Pose1

Study4

Findings1