• However, despite the drug-eluting stents superiority over the bare-metal stents, drug-eluting stent implantation had possible concerns over platelet aggregation and significant blood clotting in a localized area. (wikipedia.org)
  • [ 4 ] Restenosis remains an issue in coronary drug-eluting stent implantation for ostial RCA lesions. (medscape.com)
  • The use of this product carries the same risks associated with coronary artery stent implantation procedures, which include subacute and late vessel thrombosis, vascular complications, and bleeding events. (medtronic.com)
  • The use of a drug-eluting stent (DES) outside of the labeled indications, including use in patients with more tortuous anatomy, may have an increased risk of adverse events, including stent thrombosis, stent embolization, myocardial infarction (MI), or death. (medtronic.com)
  • Stent thrombosis is a low-frequency event that is frequently associated with MI or death. (medtronic.com)
  • Despite its reduced rates of restenosis compared to plain old balloon angioplasty, it still had high rates of stent thrombosis and required a high dosage of blood thinners. (wikipedia.org)
  • However, despite these improvements, concerns persisted on the risk of stent thrombosis. (wikipedia.org)
  • Due to inhibition of vital vascular system cells, this causes risk of stent thrombosis, and, thus, patients with drug-eluting stents are required to use dual antiplatelet therapy for approximately 12 months. (wikipedia.org)
  • The coated stent promotes the formation of an endothelial layer, which protects against thrombosis and reduces restenosis. (wikipedia.org)
  • 64-slice multidetector CT (MDCT) coronary angiography has been shown to detect poststent complications such as instent stenosis, thrombosis, stent migration and stent fractures. (hindawi.com)
  • We report a case of stent fracture in a patient who underwent RCA stenting with associated RCA perforation and almost complete thrombosis of the RCA and peristent fibrinoid collection. (hindawi.com)
  • Mortality, major adverse cardiovascular events (MACEs), target vessel failure, and stent thrombosis (ST) occur more frequently as the result of calcium-mediated poor lesion preparation, stent under expansion, and stent malapposition ( 2 ). (frontiersin.org)
  • Additionally, the primary safety measure of major adverse cardiovascular events (MACE), including death, reinfarction, stent thrombosis and stroke established the superiority of drug-eluting stents with respect to safety through one year. (dotmed.com)
  • The concern of stent thrombosis still an issue and dual antiplatlets therapy (DAPT) is mandatory for variable time ranging from one month to one year. (scirp.org)
  • Background -Extracellular matrix (ECM) remodeling contributes to in-stent restenosis and thrombosis. (mmu.ac.uk)
  • Three drugs, each of which works in a different way, are used in anti-platelet therapy to help prevent restenosis (the reclogging of blood vessels after they have been cleared with percutaneous coronary intervention or PCI) or thrombosis (obstruction of an artery or vein by a blood clot). (sciencedaily.com)
  • Delayed arterial healing, characterized by poor endothelialization, is the primary cause of late (1 month-1 year postimplantation) and very late stent thrombosis following implantation of drug-eluting stents. (nature.com)
  • The incompetent endothelium leads to late stent thrombosis and the development of in-stent neoatherosclerosis. (nature.com)
  • Although the Genous stent promotes rapid vessel healing, it did not decrease the rate of target lesion failure compared to drug-eluting stents, which increases the risk of restenosis and stent failure. (wikipedia.org)
  • However, lesions such as chronic total occlusions and bifurcations which are at increased risk of restenosis were excluded. (eur.nl)
  • However, previous studies on vascular interventions in patients with TA have shown inconsistent results, ranging from a high risk of restenosis to good longterm efficacy and patency, although open revascularization resulted in superior patency rates compared with endovascular intervention 4 , 6 , 9 , 10 , 11 . (jrheum.org)
  • DES have a thin surface of medication to reduce the risk of restenosis. (vitalheartandvein.com)
  • Genetic risk of restenosis after percutaneous coronary interventions in the era of drug-eluting stents. (cdc.gov)
  • Outcomes from prior registry and randomized trials of drug-eluting stents compared with bare-metal stents in heart attack patients have been conflicting. (dotmed.com)
  • When used in relatively simple lesions, randomized studies have demonstrated efficacy of drug-eluting stents in significantly reducing restenosis compared with bare metal stents. (eur.nl)
  • Subsequent stent restenosis or occlusion may require repeat catheter-based treatments (including balloon dilatation) of the arterial segment containing the stent. (medtronic.com)
  • This case also highlights the role of CT coronary angiography (CTCA) in detecting stent fracture and associated coronary occlusion and perforation. (hindawi.com)
  • A catheter angiography done at that time revealed total occlusion of the RCA stent, with grade III collaterals. (hindawi.com)
  • 1987) Intravascular Stents to Prevent Occlusion and Restenosis after Transluminal Angioplasty. (scirp.org)
  • Intracoronary in-stent restenosis (ISR) is more common with bare metal stents. (ijcdw.org)
  • Prospective randomized trial of corticosteroids for the prevention of restenosis after intracoronary stent implantation. (keywen.com)
  • Intracoronary stenting has improved catheter based revascularisation of obstructive coronary artery disease. (aarogya.com)
  • There are three types of stents: bare-metal stents (BMS), drug-eluting stents (DES), and bioresorbable vascular scaffolds (BRS). (wikipedia.org)
  • The first stents created were bare-metal stents where they were made from stainless steel and had poor flexibility. (wikipedia.org)
  • Initially, drug-eluting stents (DES) were compared to bare-metal stents (BMS) for efficacy. (medscape.com)
  • New York-Presbyterian Hospital and Columbia University Medical Center, together with the Cardiovascular Research Foundation (CRF), announced that its landmark study comparing the safety and efficacy of drug-eluting stents and bare-metal stents was published in the May 7 New England Journal of Medicine. (dotmed.com)
  • The study, HORIZONS-AMI (Harmonizing Outcomes with RevascularIZatiON and Stents in Acute Myocardial Infarction), showed that in heart attack patients undergoing angioplasty, the use of paclitaxel-eluting stents reduces rates of target lesion revascularization (TLR) and binary angiographic restenosis when compared to the use of bare-metal stents after one year. (dotmed.com)
  • These results now provide definitive evidence that paclitaxel-eluting stents are superior in efficacy to bare-metal stents and have a comparable safety profile at one year," says Dr. Stone. (dotmed.com)
  • The findings from the HORIZONS-AMI trial will have a major impact on how decisions are made regarding drug-eluting and bare-metal stents in the highest-risk patients, those in the early hours of a heart attack. (dotmed.com)
  • The HORIZONS-AMI trial, a prospective, open-label, multicenter, controlled study, enrolled 3,602 heart attack patients at 123 centers in 11 countries, 3,006 of whom were randomized to paclitaxel-eluting stents versus otherwise identical bare-metal stents. (dotmed.com)
  • The chief advantage of drug-eluting stents (DES) over bare-metal stents is that they significantly reduce the risk for restenosis. (jwatch.org)
  • Drug-eluting stents (DES) improved the principles of bare metal stents (BMS) by local drug release to inhibit neointimal growth. (scirp.org)
  • 2009) 5-Year Clinical Outcomes after Sirolimus-Eluting Stent Implantation Insights from a Patient-Level Pooled Analysis of 4 Randomized Trials Comparing Sirolimus-Eluting Stents with Bare-Metal Stents. (scirp.org)
  • Impairment of vasorelaxation in nonstented proximal and distal segments of stented coronary arteries is more severe with drug-eluting stents than bare-metal stents, and stent-induced flow disturbances resulting in complex spatiotemporal shear stress can also contribute to increased thrombogenicity and inflammation. (nature.com)
  • The process of neoatherosclerosis occurs more rapidly, and more frequently, following deployment of drug-eluting stents than bare-metal stents. (nature.com)
  • Currently, second-generation drug-eluting stents require long-term use of dual-antiplatelet therapy, which increases the risk of major bleeding occurrences in patients. (wikipedia.org)
  • As a result, improvements in the stent material, strut thickness, polymer, and drug choice led to the development of second-generation drug-eluting stents that showcased overall clinical enhancements to its predecessor. (wikipedia.org)
  • Dual Antiplatelet Therapy Guided by CYP2C19 Polymorphisms after Implantation of Second-Generation Drug-Eluting Stents for Management of Acute Coronary Syndrome. (cdc.gov)
  • Before withdrawing the stent delivery system, confirm complete balloon deflation using fluoroscopy to avoid arterial damage caused by guiding catheter movement into the vessel. (medtronic.com)
  • To investigate the relative importance of stent induced arterial stretch and deep injury to the development of in-stent neointima. (bmj.com)
  • Our aim in this study was to investigate the relative importance of arterial stretch and deep injury to the late arterial response after stent deployment, using moderate implantation conditions. (bmj.com)
  • Coronary stents are generally indicated to increase coronary vessel diameter in the setting of ischemia due to coronary blockage, either by a combination of acute recoil, arterial contraction of a previously treated segment, and/or local neointimal hyperplasia. (medscape.com)
  • Coronary stent fracture is a known complication of coronary arterial stent placements. (hindawi.com)
  • Angiotensin II (AngII) stimulates oxidative stress in VSMC, inducing VSMC proliferation and migration, which is a critical factor in both developments of hypertension and angioplasty-induced arterial restenosis. (hindawi.com)
  • The problem is that when a stent is placed in an artery, it damages the arterial wall (and in particular, completely obliterates the endothelial layer). (axa-research.org)
  • The second is normal arterial wall healing, which is characterized by the stent being covered with new endothelial cells. (axa-research.org)
  • The most problematic complication of PCI, with or without stent implantation, is the restenosis defined as the re-narrowing of the enlarged artery and characterized by an immune/inflammatory response going with a hyperplastic reaction, involving smooth muscle cell (SMC) migration/proliferation, and remodelling of the arterial wall. (unina.it)
  • Local research includes assessment of biomarkers as predictors of coronary stent re-stenosis after implantation. (otago.ac.nz)
  • ISR was defined as a diameter stenosis of 50% within a coronary stent. (summit-tctap.com)
  • They found that high blood plasma levels of CMTM5 mRNA were associated with a higher rate of subsequently developing stenosis (i.e. narrowing) in their stents than patients with lower levels of this mRNA. (wikipedia.org)
  • There was no angiographic restenosis after PCB angioplasty.The present observational single-center study showed that PCB for de novo stenosis in the LV had no significant adverse impact on TLF and had favorable angiographic outcomes. (bvsalud.org)
  • After application, a re-stenosis developed and in-stent angioplasty was performed, but it was required a nephrectomy because of haemorrhage. (peertechzpublications.com)
  • Magnetic resonance (MR) angiography revealed significant (95%) stenosis in left renal artery stent and over 50% stenosis in right renal artery. (peertechzpublications.com)
  • The Onyx Frontier™ zotarolimus-eluting coronary stent system is indicated for improving coronary luminal diameters in patients, including those with diabetes mellitus or high bleeding risk, with symptomatic ischemic heart disease due to de novo lesions of length ≤ 35 mm in native coronary arteries with reference vessel diameters of 2.0 mm to 5.0 mm. (medtronic.com)
  • Compared to drug-eluting stents, dual therapy stents have improved vessel regeneration and cell proliferation capabilities. (wikipedia.org)
  • The COMBO stent is the first and only dual therapy stent that addresses the challenges of vessel healing in drug-eluting stents. (wikipedia.org)
  • The stent has an abluminal, facing vessel wall, bioabsorbable coating that continuously releases sirolimus and a luminal anti-CD34 antibody cell capture coating. (wikipedia.org)
  • The in-stent RCA was consequently completely occluded with minimal flow in a short segment of post-stent RCA and in its acute marginal branch vessel. (hindawi.com)
  • These mesh-like scaffolds, usually made of metal, are threaded into blocked arteries and the structures are then expanded, generally by inflating a balloon inside the stent, to hold the vessel open. (axa-research.org)
  • In recent years numerous animals experiments and feasibility clinical pilot trials have demonstrated that low doses of radiation when applied during coronary intervention reduce neointimal proliferation, prevent vessel contraction and alter the restenosis rate. (aarogya.com)
  • The activity levels of radioactive stents are upto 10,000 times lower than activity levels of sources used for catheter based vascular Brachytherapy, They allow uniform dose distribution with precise dosimetry because of direct source contact with the circumference of the vessel.Radioactive stents have been produced by cyclotron activation, ion implantation and proton bombardment for both beta, gamma and combination isotopes. (aarogya.com)
  • pre- or postprocedural reference vessel diameter ≥ 2.75 mm) in comparison with placement of drug-eluting stents (DESs).Consecutive de novo stenotic lesions in the LV electively and successfully treated with either PCB (n = 73) or DESs (n = 81) from January 2016 to December 2018 at our center were included. (bvsalud.org)
  • This procedure is sometimes complicated by vessel recoil and restenosis. (vitalheartandvein.com)
  • Stents are now used in more than 70% of percutaneous coronary interventions. (bmj.com)
  • In addition, the Onyx Frontier™ zotarolimus-eluting coronary stent system is indicated for treating de novo chronic total occlusions and non-left main bifurcation lesions utilizing the provisional bifurcation stenting technique. (medtronic.com)
  • Drug-eluting stents (DES) were developed in the early 2000s to reduce restenosis (ie, recurrent narrowing) rates in stented coronary lesions. (medscape.com)
  • These stents are FDA approved for single de novo coronary lesions of limited length within specific diameter size ranges. (medscape.com)
  • [ 1 ] which compared the sirolimus-eluting CYPHER stent with its noncoated counterpart, the BX velocity stent, in 238 patients with de novo lesions less than 18 mm in length in native coronary arteries 2.5-3.5 mm in diameter. (medscape.com)
  • The SIRIUS trial, which included 1058 patients with workhorse lesions who were randomly assigned to either sirolimus-eluting stents or BMS, demonstrated the long-term efficacy and safety of sirolimus-eluting stents. (medscape.com)
  • In a 5-year study of outcomes from the j-CYPHER registry which compared sirolimus-eluting stent treatment in 397 patients with ostial right coronary artery (RCA) lesions with 3716 patients with nonostial RCA lesions, researchers concluded that sirolimus-eluting stent implantation for ostial RCA was associated with a higher risk of target legion revascularization than when used in patients with nonostial RCA lesions. (medscape.com)
  • A total of 87 de novo lesions were treated by IVL with the following indications: 25 before attempting other balloon-based devices (primary IVL), 51 after the failure of non-compliant balloon dilatation (secondary IVL), and 11 after stent implantation because of stent under expansion (bailout IVL). (frontiersin.org)
  • In 23 lesions, IVL was used for the treatment of in-stent restenosis (ISR). (frontiersin.org)
  • Revascularization procedures, including balloon angioplasty with or without stenting, are often used for the treatment of steno-occlusive lesions 6 , 7 , 8 . (jrheum.org)
  • Uses of balloon catheters or BMS for the treatment of coronary artery lesions shows good short-term results but long-term follow up revealed restenosis in up to 20%-30% of patients. (scirp.org)
  • Despite the improved outcomes with stenting, restenosis occurs at a high rate, especially in smaller vessels and in longer lesions. (aarogya.com)
  • Assessment of the effectiveness and durability of the endovascular treatment with the stent implantation of the popliteal artery lesions. (czytelniamedyczna.pl)
  • Between March 2012 and October 2015, 24 patients with popliteal artery lesions underwent angioplasty with a stent implantation. (czytelniamedyczna.pl)
  • Gore ® Tigris ® Vascular Stent is an effective and safe option in the endovascular management of the atherosclerotic lesions in popliteal artery with a satisfactory durability of the treatment. (czytelniamedyczna.pl)
  • The aim is the further development of drug-eluting stents that significantly reduce the rate of restenosis. (uni-rostock.de)
  • p32 is a pure particle emitting radioisotope and has a short half-life (14.3 days) and a limited range of tissue penetration (3-4mm) It is the radioactive isotope being used in the Isonipsi trial to assess the role of beta radiation in reducing the rate of restenosis. (aarogya.com)
  • The paclitaxel-eluting stent had a rate of 10.0 percent and the bare-metal stent had a rate of 22.9 percent. (dotmed.com)
  • In this thesis, contemporary percutaneous coronary intervention of these lesion subsets are evaluated, including assessment of the efficacy of sirolimus- and paclitaxel-eluting stent implantation. (eur.nl)
  • Drug-eluting stents inhibit the growth of endothelial cells and vascular smooth muscle cells, which are essential for in-stent endothelialization. (wikipedia.org)
  • The sirolimus drug reduces the risk of stent restenosis through inhibiting the formation of neointima while the anti-CD34 antibody coating reverses the inhibition of local endothelial cells from the sirolimus elution. (wikipedia.org)
  • The Genous stent is a coronary artery stent coated with anti-CD3 monoclonal antibodies that bind with circulating endothelial cells to the stent. (wikipedia.org)
  • This study aims to demonstrate the impact of main-branch ISR (MB-ISR) on mortality and to clarify the optimal strategy.METHODS: Between 2002 and 2008, 482 consecutive UDLM patients treated with drug eluting stent (sirolimus and paclitaxel) were evaluated.RESULTS: During follow-up period (median 52.6 months), MB-ISR occurred in 29, SB-ISR in 65, and MB/SB-ISR in 24. (unisr.it)
  • Antiproliferative drugs like sirolimus and paclitaxel were used in the first-generation drug-eluting stents to inhibit the migration of vascular smooth muscle cells and restenosis. (wikipedia.org)
  • Stretch of the coronary artery in a stent is common, and a major contributor to neointima formation, even in the absence of deep injury. (bmj.com)
  • Where neither deep injury nor stretch are seen, the stent has no effect upon the development of neointima. (bmj.com)
  • 4 High pressure deployment, wide strut openings, asymmetrical deployment, and increased balloon compliance may also contribute to in-stent restenosis or experimental neointima formation. (bmj.com)
  • 5- 8 The balance to be achieved is, therefore, in attaining adequate final stent dimensions without an excess of vascular injury, because vascular injury is intimately linked to in-stent neointima formation. (bmj.com)
  • but with more moderate implantation, the contribution of stretch to neointima formation may be underestimated. (bmj.com)
  • Stented segments were harvested 1, 3, 7, 14 and 28 days post-stenting for proteomics analysis of the media and neointima. (mmu.ac.uk)
  • After stent implantation, proteins involved in regulating calcification were upregulated in the neointima of DES. (mmu.ac.uk)
  • Thus, coronary artery stents were created to prevent restenosis after balloon dilation. (wikipedia.org)
  • The scientists analyzed data from the Cilostazol for RESTenosis (CREST) Trial, a randomized clinical trial testing the efficacy of cilostazol to prevent restenosis after PCI. (sciencedaily.com)
  • The stent was completely thrombosed and the distal post-stent RCA showed faint opacification beyond the fractured site (Figures 3 and 4 ). (hindawi.com)
  • Despite its important clinical implications little is known about ECM changes post-stent implantation. (mmu.ac.uk)
  • Instead of the classical surgical approach, percutaneous balloon angioplasty or endovascular stenting have recently become accepted procedures in the attempt to revascularize the stenotic kidney and prevent chronic renal insufficiency. (biomedcentral.com)
  • Our objective was to perform an extraction of the pacemaker and defibrillation electrodes, to allow the passage of a support wire to achieve the implantation of the endovascular stent(s) to correct the SVC syndrome. (hvt-journal.com)
  • Combined treatment of lead extraction and endovascular stent implantation corrected the syndrome in all cases. (hvt-journal.com)
  • The SVCS treatment includes corticosteroids and anticoagulation, although angioplasty and surgery with endovascular stents is the preferred therapeutic option (1, 6, 7). (hvt-journal.com)
  • Recently, the use of ionising radiations received much interest as a new treatment tool to reduce restenosis after coronary angioplasty. (aarogya.com)
  • We have done a retrospective study for all patients who underwent DES implantations at Integrated Cardiac Care Center, Dr. Soetomo Hospital, Surabaya, Indonesia, between January 2020 and October 2022. (summit-tctap.com)
  • We enrolled total 335 patients (mean age 58.56 10.92 years and 81.2% were men) who underwent angiography and DES implantation. (summit-tctap.com)
  • Different components of DES which include the polymers, drugs and the stents underwent progressive evolution, and these led to development of new generations of DES with variable types of drugs and polymers to fully absorbable stents. (scirp.org)
  • 1 Immediate contributors to in-stent restenosis include recoil (particularly in coil stents) and underexpansion. (bmj.com)
  • It is known from intravascular ultrasound (IVUS) studies that in-stent dimensions and stent length are the main predictors of in-stent restenosis. (bmj.com)
  • [ 2 , 3 ] There was significant improvement in angiographic results (in stent late lumen loss: 0.17 mm vs 1.00 mm) as well as clinical outcomes (binary in-lesion restenosis: 8.9% vs 36.3%) in the sirolimus stent treatment group relative to the BMS group. (medscape.com)
  • When drug-eluting stents (DES) are used outside the specified Indications for Use , patient outcomes may differ from the results observed in the RESOLUTE pivotal clinical trials. (medtronic.com)
  • Background: The prognostic impact of CHADS2, CHA2DS2-VASc, and CHA2DS2-VASc-HS scores on clinical outcomes after drug-eluting stent (DES) placement has not been fully elucidated. (bvsalud.org)
  • ABSORB Trials Late Outcomes: No Clinical Gains for Bioresorbable Scaffold The everolimus-eluting bioresorbable scaffold did not fare well, clinically or in late lumen loss, against the Xience stent in the 3-year results from ABSORB II and 2-year results from ABSORB China. (medscape.com)
  • Patients who are judged to have a lesion that prevents complete inflation of an angioplasty balloon or proper placement of the stent or stent delivery system. (medtronic.com)
  • Stent placement should only be performed at hospitals where emergency coronary artery bypass graft surgery can be readily performed. (medtronic.com)
  • It is hence a rare case of stable RCA perforation following stent placement. (hindawi.com)
  • However, the patient had recurrent angina within a month of stent placement. (hindawi.com)
  • Angioplasty is the stretching of an artery to widen it, followed by stent placement. (orlandocvi.com)
  • 1994) A Randomized Comparison of Coronary-Stent Placement and Balloon Angioplasty in the Treatment of Coronary Artery Disease. (scirp.org)
  • The first implanted drug-eluting stent occurred in 1999, which revolutionized the course of interventional cardiology. (wikipedia.org)
  • A 59 year old male with strong Family H/o IHD was offered a 'Radiated Stent' on 1st of Jan.1999 at Ruby Hall Clinic, the first such procedure for the city of Pune. (aarogya.com)
  • A review Coronary Angiogram in August 1999 shows normal stent appearance with no norrowing. (aarogya.com)
  • Furthermore, the Genous stent promotes coronary vascular repair response and reduces neointimal hyperplasia after stent implantation. (wikipedia.org)
  • Neointimal hyperplasia after vascular injury plays a critical role in the process of vascular restenosis, but the mechanism has not been fully elucidated yet [ 3 ]. (hindawi.com)
  • This thesis presents research on systems for wirelessly monitoring blood pressure inside a vascular stent. (ubc.ca)
  • All procedures were performed with Gore ® Tigris ® Vascular Stent. (czytelniamedyczna.pl)
  • No cheap and non-invasive method for detecting the onset of restenosis currently exists, and in-stent wireless blood pressure monitoring may provide a solution.In this work, several monitoring methods are explored. (ubc.ca)
  • The percutaneous coronary intervention with implantation of a stent is the preferred method for the treatment of cardiovascular diseases. (uni-rostock.de)
  • The connected stents could come into their own here," explains Abdul Barakat, professor at the Ecole Polytechnique in Palaiseau near Paris and holder of the AXA Chair for Cardiovascular Engineering , who is helping to develop the devices in collaboration with Instent , a start-up created in 2014 with his former PhD student Franz Bozsak. (axa-research.org)
  • Association of CYP2C19*2 polymorphism with clopidogrel response and 1-year major adverse cardiovascular events in a multiethnic population with drug-eluting stents. (cdc.gov)
  • Stents may either come as a bare metal stent or a drug eluting stent. (orlandocvi.com)
  • Researchers in France are developing a new smart, connected stent containing sensors that can non-invasively monitor how an artery heals after stent implantation. (axa-research.org)
  • During a period of several weeks, the artery heals around the stent. (vitalheartandvein.com)
  • Stenting of RAS due to atherosclerosis is followed by stabilization or improvement of Ccr, mainly at the stented kidney, while contralateral renal function showed a decrease. (biomedcentral.com)
  • Conclusions -Significant differences were identified by proteomics in the ECM of coronary arteries after BMS and DES implantation, most notably an upregulation of aggrecan, a major ECM component of cartilaginous tissues that confers resistance to compression. (mmu.ac.uk)
  • As a result, dual therapy stents were developed to reduce the long-term need for dual-antiplatelet therapy. (wikipedia.org)
  • The development of dual therapy stents resulted from the health risks of long-term use of dual antiplatelet therapy from drug-eluting stents. (wikipedia.org)
  • The chief disadvantages of DES are their greater cost and the requirement for prolonged dual antiplatelet therapy after implantation. (jwatch.org)
  • The long-term outcome following repeat catheter-based treatments of previously implanted stents is not well characterized. (medtronic.com)
  • Care should be taken to control the position of the guide catheter tip during stent delivery, stent deployment, and balloon withdrawal. (medtronic.com)
  • A relook at the previous catheter angiography revealed the stent fracture (retrospectively), which was missed during catheter angiography. (hindawi.com)
  • A balloon catheter, placed over a guidewire, is used to insert the stent into the narrowed artery. (vitalheartandvein.com)
  • This is a rare case of stent fracture with perforation of the RCA. (hindawi.com)
  • The stent itself was bent at two sites, with a complete fracture in its mid part (Figures 2 and 3 ). (hindawi.com)
  • In an effort to improve on current therapy for restenosis we are prompted to consider new strategies for prevention and treatment, focusing on understanding of molecular mechanisms and identifying possible therapeutic targets. (unina.it)
  • 1996) Patterns and Mechanisms of In-Stent Restenosis. (scirp.org)
  • Since the restenosis (re-narrowing) rate is high in angioplasty, a stent is often placed to ensure the blood flow and patency of the artery. (orlandocvi.com)
  • The primary patency rate was 91.30% in 6 months after the stent implantation, and 86.96% in 12 months after the procedure. (czytelniamedyczna.pl)
  • Introduction: In-stent restenosis (ISR) is a major challenge in interventional cardiology. (monocyte.eu)
  • This study removes much of the uncertainty and concern about the efficacy and safety of drug-eluting stents in this clinical setting. (dotmed.com)