InflammationInnate and adaptive immuneHumoral immunityEuropean Journal of ImmunolFish and Shellfish ImmunologyComparative ImmunologyBiochemistryAutoimmunityLymphocytesAnti-tumor immunityInfectionsTissuesVirologySystems immunologyFrontiersPathogensMicrobiology and ImmunologyAntibodiesMolecularAmerican AcademyHuman immunologyBiologyAntigen-specificResearchCellularImmunologicCancerMicroorganismsAntibodyMechanisms of actVaccine developmentCellMoleculesPathogenesisIntestinalTherapeuticSeminarLaboratory
Inflammation6
- Since January 2015, ITMO I3M has been coordinating research in areas of Immunology, Inflammation, Infectious disease and Microbiology (I3M). (aviesan.fr)
- ITMO I3M resulted from the linking of the themes "Microbiology and infectious diseases" and "Immunology and inflammation. (aviesan.fr)
- The initiative entitled "Immunology & Inflammation" brings together immunology research - which is spread out over various Helmholtz Centers - in a common structure. (mdc-berlin.de)
- One of the research areas at the MDC is immunology and inflammation, which covers tumor immunology, DNA repair in B lymphocytes, the role of tumor stroma-immune cell interaction in cancers, the role of innate immune cells in gliomas and neurodegenerative diseases, and the development of immunotherapy strategies. (mdc-berlin.de)
- Innate immunity, our body's first line of defense, can destroy foreign invaders and trigger inflammation that contributes to their demise. (scripps.edu)
- There is a great deal of synergy between the adaptive immune system and its innate counterparts, and deficiencies in either system can trigger disease or disease, such as inappropriate inflammation, autoimmune disease, immunodeficiency disorders, and hypersensitivity. (eitc.org)
Innate and adaptive immune4
- However, recent studies emphasize that the individual contribution of each of these cell subsets is not sufficient and that interactions between these different populations of T cells and the simultaneous activation of innate and adaptive immune pathways in distinct gut compartments are required to promote disease immunopathology. (frontiersin.org)
- In this review, we will discuss how tissue destruction in the context of coeliac disease results from the complex interactions between gluten, HLA molecules, TG2, and multiple innate and adaptive immune components. (frontiersin.org)
- Generally, women display enhanced innate and adaptive immune responses when compared to men, resulting in less severe infections and increased response to vaccinations. (lu.se)
- Repeated organic dust exposures modulate innate and adaptive immune function with a resultant adaptation-like response. (cdc.gov)
Humoral immunity2
- Because these fluids were traditionally known as humors , antibody-mediated immunity is sometimes known as, or considered a part of, humoral immunity . (wikipedia.org)
- Immunoglobulin (Ig) is the key component of humoral immunity. (medscape.com)
European Journal of Immunol2
- European Journal of Immunology 42(9), pp. 2383-2394. (cardiff.ac.uk)
- European Journal of Immunology, 46 (1), 147 - 153. (up.pt)
Fish and Shellfish Immunology2
Comparative Immunology4
- Developmental and Comparative Immunology. (uib.no)
- Functional characterization of IgM+ B cells and adaptive immunity in lumpfish (Cyclopterus lumpus L.). Developmental and Comparative Immunology. (uib.no)
- From this we can see the difference between human immunology and comparative immunology in veterinary medicine and animal bioscience. (eitc.org)
- Moreover, we are focused on the role of the innate immune system in chronic inflammatory diseases, allergy and autoimmunity, neurodegenerative diseases, tumor immunology, comparative immunology, resistance to pathogens, and to other environmental risks ( e.g. , micro- and nano-particles/plastics). (immunologicnr.it)
Biochemistry1
- We use a combination of experimental systems including mouse genetics, cellular immunology and biochemistry, as well as models of cancer, infection an autoimmune disease. (stjude.org)
Autoimmunity1
- The behavior of T cells as regulators of adaptive immune responses and as effector cells is also being examined in models of bacterial/viral infection and in disease conditions such as autoimmunity, immunodeficiencies and cancer. (immunologicnr.it)
Lymphocytes4
- T cell immunity is at the center of the disease contributing to the inflammatory process through the loss of tolerance to gluten and the differentiation of HLA-DQ2 or HLA-DQ8-restricted anti-gluten inflammatory CD4 + T cells secreting pro-inflammatory cytokines and to the killing of intestinal epithelial cells by cytotoxic intraepithelial CD8 + lymphocytes. (frontiersin.org)
- We aim at deciphering the mechanisms underlying the role of T and B lymphocytes in adaptive immune responses as well as to the interactions between the adaptive immune system and different tissues during disease pathogenesis to attempt novel therapeutic approaches. (immunologicnr.it)
- Chapman NM, Chi H . Metabolic adaptation of lymphocytes in immunity and disease. (stjude.org)
- Immunologic memory cells typically include B-Lymphocytes T-Lymphocytes and sometimes adaptive NK cells. (bvsalud.org)
Anti-tumor immunity2
- Our research further revealed that inhibiting IRE1 activity in cancer-surveilling dendritic cells augments anti-tumor immunity. (gene.com)
- June 23, 2023 B cells are thought to play a critical role in innate and adaptive immunity, but their exact role in anti-tumor immunity remains unknown. (sciencedaily.com)
Infections1
Tissues1
- The cells that have the inherent property of innate and adaptive immunity within the body are present at different sites including the blood, lymphatic system (lymph, lymphoid nodules and lymphoid organs), epithelium, and connective tissues. (medscape.com)
Virology1
- Immunology has applications in many medical disciplines, especially in the fields of rheumatology, virology, allergy (dermatology), bacteriology, oncology and further transplant medicine. (eitc.org)
Systems immunology2
- Chi H . Immunometabolism at the intersection of metabolic signaling, cell fate, and systems immunology. (stjude.org)
- In the Systems Immunology Lab at Lund University ( https://theconsigliolab.wordpress.com/ ), we investigate how biological sex impacts human immunity using systems immunology approaches. (lu.se)
Frontiers2
- Transcriptome-wide analyses of early immune responses in lumpfish leukocytes upon stimulation with poly(I:C). Frontiers in Immunology. (uib.no)
- Frontiers in Immunology. (uib.no)
Pathogens2
- In addition to structural and chemical barriers against pathogens, the immune system has two basic lines of defense: innate and adaptive immunity. (eitc.org)
- Innate immunity is the first immune mechanism against invading pathogens. (eitc.org)
Microbiology and Immunology1
- Microbiology and Immunology. (wikipedia.org)
Antibodies4
- Together with B and T cells , antibodies comprise the most important part of the adaptive immune system . (wikipedia.org)
- After an antigen binds to a BCR, the B cell activates to proliferate and differentiate into either plasma cells , which secrete soluble antibodies with the same paratope, or memory B cells , which survive in the body to enable long-lasting immunity to the antigen. (wikipedia.org)
- Passive immunity happens when you receive antibodies to a disease instead of making them through your own immune system. (medlineplus.gov)
- People can also get passive immunity through blood products that contain antibodies. (medlineplus.gov)
Molecular3
- Immunology measures, uses diagrams and differentiates the study of immunity at the cellular and molecular levels in a medical context, the immune system as part of the physiological level because it is so important for its function. (eitc.org)
- Innate immunity recognizes mainly molecular patterns that are broadly distributed rather than an antigen specific to one organism or cell. (msdmanuals.com)
- Training/knowledge of immunology, as well as experience with cell culture and molecular biology are both desired but not required. (lu.se)
American Academy1
- American Academy of Allergy, Asthma & Immunology (AAAAI) is ac- port from the National Institutes of Health (NIH). (cdc.gov)
Human immunology1
- We are looking for a MSc student (ideally over 20-week project) interested in wetlab training in human immunology, with the possibility of developing skills in computational methods of data analysis. (lu.se)
Biology2
- Immunology is the branch of medicine and biology that encompasses the medical study of the immune systems of humans, animals, plants, and intelligent species. (eitc.org)
- During the course, the students also practice to analyse and discuss scientific material focussed on immunology and infection biology. (lu.se)
Antigen-specific1
- On the other hand, adaptive immunity is antigen-dependent and antigen-specific. (eitc.org)
Research6
- Five Helmholtz Centers are joining forces in a new initiative that aims to advance immunology research and the development of new therapies. (mdc-berlin.de)
- There is a mood of optimism among the immunology community, because the past few years have seen great strides made in immune system research. (mdc-berlin.de)
- It is the nucleus for an undertaking that intends to position the Helmholtz Association as a main player in application-oriented immunology research internationally. (mdc-berlin.de)
- Aside from new and joint research projects, the training of the next generation of basic and clinical researchers in immunology, as well as scientific exchange, is also in the focus of the future topic. (mdc-berlin.de)
- Cancer Immunology Research 1(6), article number: 416. (cardiff.ac.uk)
- In recent decades, scientists in the field of immunology have published research showing a direct link between immune system dysregulation and disease development. (eitc.org)
Cellular1
- Here we compare antibody and cellular immunity in children (aged 3-11 years) and adults. (nature.com)
Immunologic2
- Innate (natural) immunity does not require prior exposure to an antigen (ie, immunologic memory) to be fully effective. (msdmanuals.com)
- Building immunologic memory cells is a basis of how a vaccine affords immunity to a specific pathogen. (bvsalud.org)
Cancer3
- 2017. Effect of modified vaccinia Ankara-5T4 and low-dose cyclophosphamide on antitumor immunity in metastatic colorectal cancer: A randomized clinical trial . (cardiff.ac.uk)
- In their review " Natural and Adaptive Immunity to Cancer ", Vesely and colleagues draw from recent mouse models of cancer and human clinical data to describe how cells, effector molecules, and pathways of the immune system act to suppress and control tumor cells. (massgenomics.org)
- Our laboratory has a long-standing interest in immune signaling and cell metabolism underlying the differentiation and function of T cells, a central cell type in adaptive immunity and cancer immunotherapy. (stjude.org)
Microorganisms3
- If microorganisms make it past this gauntlet, the body calls on adaptive immunity. (scripps.edu)
- our adaptive immune system also stores "memories" of the offending microorganisms to be on the alert for future attacks. (scripps.edu)
- Adaptive immune mechanisms recognize and neutralize foreign molecules or microorganisms in a specific manner. (lu.se)
Antibody1
- Attack by phagocytic cells can be facilitated when antigens are coated with antibody (Ab), which is produced as part of acquired immunity, or when complement proteins opsonize antigens. (msdmanuals.com)
Mechanisms of act1
Vaccine development1
- Our laboratory investigates innate and adaptive immunity and microbial pathogenesis, especially in regards to vaccine development. (bu.edu)
Cell7
- These data illustrated that whereas CD47/SIRPα inhibition could potentiate tumor cell phagocytosis, CD40-mediated activation of a type I interferon response provided a bridge between macrophage- and T-cell-mediated immunity that significantly enhanced durable tumor control and rejection. (aacrjournals.org)
- 2012. Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4+T-cell immunity . (cardiff.ac.uk)
- 2018. Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and is Critical to Trained Immunity. (bu.edu)
- It also complemented Steinman's discovery of a new cell type he called the dendritic cell, which activates elements of the adaptive immune system. (scripps.edu)
- Moreover we study the effects of compounds and natural substances on cell mediated immunity, the role of HLA-DR in immune escape and metastatic progression and we propose gene correction and gene editing of primary immunodeficiencies (RAG defects). (immunologicnr.it)
- Hypothesis: RNA and DNA Viral Sequence Integration into the Mammalian Host Genome Supports Long-Term B Cell and T Cell Adaptive Immunity. (cdc.gov)
- CRTH2: Chemoattractant receptor-homologous molecule expressed includes nonallergic asthma phenotypes, such as asthma on TH2 cells associated with exposure to air pollution, infection, or obesity, ILC: Innate lymphoid cell that require innate rather than adaptive immunity. (cdc.gov)
Molecules1
- Deficiencies are highly variable with regard to symptoms, phenotype, genotype, severity, etc, because many cells and molecules are required for both natural and adaptive immunity . (lu.se)
Pathogenesis1
Intestinal1
- Spatial distribution of LTi-like cells in intestinal mucosa regulates type 3 innate immunity. (stanford.edu)
Therapeutic1
- Immunology is undeniably a pivotal part of medicine, and a source of prophylactic solutions (vaccines) and therapeutic agents in many medical disciplines. (aviesan.fr)
Seminar1
- The seminar series is a wonderful opportunity for all members of the Center for Immunology and the University to have a chance to meet and discuss science with other members of the science community from around the globe. (umn.edu)
Laboratory2
- During the laboratory course „State of the Art" technologies relevant in modern Immunology will be acquired. (uni-regensburg.de)
- The laboratory course can be completed in one of the working groups within the Institute of Immunology and should be finished by the end of the following summer semester. (uni-regensburg.de)