• A follow-up study of immunologic and virologic markers in relation to disease progression was undertaken on asymptomatic HIV-1 positive blood donors with history of oral iron intake (subgroup I) compared to those without such history (subgroup II). (scirp.org)
  • We evaluated the rate of switching to second-line antiretroviral therapy (ART), and the impact of delayed switching on immunologic, virologic, and mortality outcomes in the Rakai Health Sciences Program (RHSP) Clinical Cohort Study which started providing ART in 2004 and implemented 6 monthly routine virologic monitoring beginning in 2005. (biomedcentral.com)
  • Immunologic decline after virologic failure was defined as decrease in CD4 count of ≥50 cells/ul and virologic increase was defined as increase of 0.5 log 10 copies/ml. (biomedcentral.com)
  • Competing risk models were used to summarize rates of switching to second-line ART while cox proportional hazard marginal structural models were used to assess the risk of virologic increase or immunologic decline associated with delay to switch first line ART failing patients. (biomedcentral.com)
  • Using data from the Rakai Health Sciences Program (RHSP) Clinical Cohort Study, which monitors HIV care programs, we retrospectively assessed the rate and factors associated with switching from first- to second-line ART among HIV-infected adults with virologic failure 6 months after ART initiation, and evaluated the impact of delayed switching on immunologic, virologic, and mortality outcomes. (biomedcentral.com)
  • Biochemical and immunologic markers for bladder cancer are reviewed. (cdc.gov)
  • The present prospective study, carried out over fifteen years, describes the pattern of natural course of disease progression in a group of ART naive male professional blood donors with asymptomatic HIV-1 infection in relation to serum iron status, viral load, peripheral CD4 + T lymphocyte count, serum levels of cytokines and immune activation markers viz. (scirp.org)
  • Bone mineral density, biochemical markers of bone remodeling, calciotropic hormone levels, biochemically evaluated nutritional and immunologic status, and muscle strength were measured every 6 months. (acpjournals.org)
  • In the face of substantial evidence that a good immunologic status has been tied to a better prognosis, Dr. Greenspan believes an assessment of immunologic status should be part of the initial clinical workup of every cancer patient and an essential tool in treatment planning. (cancernetwork.com)
  • In 41 primary Sjögren's syndrome patients we compared fatty acid levels within erythrocyte phospholipids, plasma phospholipids, plasma triglycerides and plasma cholesterol esters, with the immunopathological and clinical disease status. (omega-research.com)
  • Sigma n-3 EFA/sigma n-6 EFA ratios correlated significantly to the quantitative estimates of immunopathological and clinical disease status. (omega-research.com)
  • Leprosy has six clinical manifestations according to the Ridley-Jopling clinical classification, which includes two ends of a spectrum "determined by immunologic status with lepromatous leprosy (LL) on one end with least immunity and tuberculoid leprosy (TL) on the other with strong immunity. (medpagetoday.com)
  • In their Journal of Allergy and Clinical Immunology article , the researchers define immunologic resilience as the capacity to preserve or restore immune competence and control inflammation in the face of infection or other antigenic challenges. (globalhealthnewswire.com)
  • Clinical and immunologic outcome of 42 individuals with trimellitic anhydride-induced immunologic lung disease after transfer to low exposure. (northwestern.edu)
  • The purpose of this study is to determine the clinical and immunologic status of trimellitic anhydride (TMA)-exposed employees who have had immunologic lung disease and who have been moved to lower-exposure jobs. (northwestern.edu)
  • The density of P. jiroveci clusters in BAL samples did not correlate with prior co-trimoxazole use, immunologic status of the patient or overall mortality. (unboundmedicine.com)
  • Co-first author Marcos Restrepo, MD, MSc, PhD, professor of medicine at the health science center and director of the medical intensive care unit in the South Texas Veterans Health Care System, said the immune health grades and overall concept of immunologic resilience accurately predicted most patient outcomes, which in addition to mortality included hospitalization, need for advanced respiratory support, and levels of SARS-CoV-2 in the nasopharynx. (globalhealthnewswire.com)
  • Supplementation with vitamin D has been demonstrated to reduce the incidence of acute respiratory tract infections.In addition, data from around the world indicate that low vitamin D status correlates with increased incidence and severity of, and mortality from, COVID-19. (creighton.edu)
  • Immunologic responses may range from classic allergic mast cell activation to immune complex formation. (medscape.com)
  • However, with age, the proportion of individuals with capacity to preserve immunologic resilience declines, contributing to the greater burden of COVID-19 in older persons. (globalhealthnewswire.com)
  • There is also a 6 monthly immunologic monitoring and targeted plasma viral load testing is used to confirm immunologic failure. (mediaforfreedom.com)
  • Encephalitis can occur as a secondary immunologic complication of certain viral infections or vaccinations. (merckmanuals.com)
  • Unfortunately, efforts to address the health status are often impaired by inability to access biologic samples. (vin.com)
  • Any prior therapy directed at the malignant tumor, including chemotherapy, biologic/targeted agents, and immunologic agents must be discontinued at least 28 days prior to tumor resection. (moffitt.org)
  • Metrics tracking inferior immunologic resilience predicted up to 19-times higher risk of dying within 30 days, which was the primary outcome of the study. (globalhealthnewswire.com)
  • In a case series design, 42 consecutive employees with TMA-induced immunologic lung disease were studied after they had been moved to low-exposure jobs for more than 1 year. (northwestern.edu)
  • Supplementation to improve vitamin D status and support immunity is recommended by experts in nutrition and immunity.However, optimization of vitamin D status can take months with the currently available forms of vitamin D. (creighton.edu)
  • Symptoms include fever, headache, and altered mental status, often accompanied by seizures or focal neurologic deficits. (merckmanuals.com)
  • Effects of brain death and hemodynamic status on function and immunologic activation of the potential donor liver in the rat. (ox.ac.uk)
  • Irrespective of hemodynamic status, a progressive inflammatory activation could be observed in brain-dead rats compared with controls. (ox.ac.uk)
  • The abnormalities in the cytokine network were most pronounced in patients with the most severe heart failure, and several of the immunologic parameters, in particular soluble gp130, were correlated with variables reflecting deranged hemodynamic status. (nih.gov)
  • Conceivably, durability of vaccines may wane in persons with inferior immunologic resilience, the researchers wrote. (globalhealthnewswire.com)
  • Clarify the appropriate use of immunologic (CD4 count) monitoring in the care of patients with HIV. (hivguidelines.org)
  • Essential fatty acid status in cell membranes and plasma of patients with primary Sjogren's syndrome. (omega-research.com)
  • When COVID patients get new lungs, should vaccine status matter? (npr.org)
  • Researchers from The University of Texas Health Science Center at San Antonio and the South Texas Veterans Health Care System have unveiled a novel concept, "immunologic resilience," to accurately predict which COVID-19 patients will advance to severe disease and which will not. (globalhealthnewswire.com)
  • The scientists developed novel metrics to monitor immunologic resilience and evaluated them in 522 patients with COVID-19 at Audie L. Murphy Memorial Veterans Hospital in San Antonio, a hospital of the U.S. Department of Veterans Affairs (VA). Each patient's level of immunological resilience was assessed on the day of admission and then daily for varying durations. (globalhealthnewswire.com)
  • One reason this is important is that we are measuring immunologic resilience on the first day, before the patients receive therapy," Dr. Restrepo said. (globalhealthnewswire.com)
  • These results show plainly the connection between CAD severity and the lipid, glucose, coagulation, and immunologic status of CAD patients, and substantiate the importance of sufficient treatment in this group of patients - in particular, CAD patients suffering from type 2 diabetes mellitus. (dovepress.com)
  • Results Sixty-six patients were screened and 19 enrolled of whom 14 received at least 3 doses of the vaccine and thus evaluated for the primary immunologic endpoint. (bmj.com)
  • Efforts were made to evaluate immunologic health via leukocyte phenotyping and lymphocyte function. (vin.com)
  • After all neoadjuvant study therapy is administered, each subject will undergo cystectomy to evaluate pathologic response to treatment and for immunologic characterization in the resected tissue. (bcan.org)
  • Considering that such practice of consumption of iron tablets by the donors was not based on any physiological consideration to the quantum of blood loss through donation, it was of interest to find out if any alteration in the serum iron status could be related to disease progression and survival of the HIV-1 infected blood donors. (scirp.org)
  • Assay parameters were evaluated while simultaneously gaining knowledge about monk seal genetics, disease exposure and basic and immunologic health. (vin.com)
  • The researchers quantified immunologic resilience through "immune health grades," which are based on measures of infection-fighting T cells, and blood cell gene expression signatures. (globalhealthnewswire.com)
  • Rotheram-Borus 2001a) These seven studies are described below, based on type of intervention utilized to support disclosure of positive HIV status. (bvsalud.org)
  • The aim of this study was to diagnose pyometra and related sepsis status using cost-effective nutritional-immunological indices, antioxidants, and toxin levels in dogs and to investigate the utility of the indices in predicting toxin and antioxidant status. (bvsalud.org)
  • 1 The immunization schedule is designed to create the best immunologic response and achieve maximal disease prevention. (aafp.org)
  • They can mention that immunologic response is greater in younger adolescents, so earlier immunization is prudent. (aafp.org)
  • Our approach will identify unique immunologic biosignatures driven by where the child sits on the TB disease spectrum, as well as by HIV-exposure status. (ohsu.edu)
  • OBJECTIVE: To assess the effect on the function and immunologic status of potential donor livers of the duration of brain death combined with the presence and absence of hemodynamic instability in the donor. (ox.ac.uk)
  • At present, 25-hydroxyvitamin D3 is not available as a dietary supplement in the United States.If it were available, 25-hydroxyvitamin D3 could more rapidly and effectively optimize vitamin D status and support immune function. (creighton.edu)
  • Further, brain death activates the inflammatory status of the potential donor liver, irrespective of the presence of hypotension. (ox.ac.uk)
  • Remarkably, irrespective of their COVID-19 status, men have inferior immunologic resilience, which may explain why they are predisposed to worse COVID-19 outcomes," Dr. Lee said. (globalhealthnewswire.com)
  • The inflammatory status of the liver was assessed by determining the immediate early gene products, the expression of cell adhesion molecules, and the influx of leukocytes in the liver. (ox.ac.uk)
  • Here they help to educate the public about their fragile status. (vin.com)
  • Because of the complexity of care required by VLBW infants, their fragile health status, and their anatomic, physiologic and immunologic immaturity, they simultaneously have a high risk for adverse outcomes and a low tolerance for poor care processes. (news-line.com)
  • The Immunologic Constant of Rejection (ICR), is a notion introduced by biologists to group a shared set of genes expressed in tissue destructive-pathogenic conditions like cancer and infection, along a diverse set of physiological circumstances of tissue damage or organ failure, including autoimmune disease or allograft rejection. (wikipedia.org)
  • It was of interest to find out if disease course in HIV type-1 infection could have any relation with alteration in body iron status among individuals with history of oral iron intake. (scirp.org)
  • In fact, the level of immunologic resilience that precedes COVID-19 and develops during the viral disease is a strong predictor of COVID-19 outcomes regardless of age, they wrote. (globalhealthnewswire.com)
  • Should adolescents with HIV infection disclose their HIV status to parents, family members, sexual partners, others? (bvsalud.org)
  • PICO 3b: What is the best way to support adolescents to disclose their HIV status safely and effectively? (bvsalud.org)
  • [ 3 ] So-called breast milk allergy is a status of food allergy induced in breastfed babies by heterologous proteins (typically cow's milk proteins) ingested by their mothers and appearing in their breast milk. (medscape.com)
  • A recent study of over 190,000 people in the United States confirms that low vitamin D status strongly correlates with increased rates of infection with SARS-CoV-2, the virus that causes COVID-19.This finding was consistent regardless of age, gender, race/ethnicity, or latitude. (creighton.edu)
  • An 18-year-old could have inferior immunologic resilience, resulting in a high risk of severe COVID-19, whereas an 80-year-old with robust resilience could manifest less severe COVID-19. (globalhealthnewswire.com)
  • It is noted that most workers at high risk for bladder cancer receive no screening and most do not even know of their high risk status. (cdc.gov)
  • Immunologic staging performed before and after primary surgery would further help answer the question of whether a patient with a large but regressed tumor can ever be restored to normal immune competence. (cancernetwork.com)
  • The biggest blind spot, in his opinion, relates to the immunologic status of the cancer patient. (cancernetwork.com)
  • But because the patient was anorectic, which has been associated with immunologic changes, Dr Hohlfeld does not think this one case report should affect general recommendations on use of alemtuzumab. (medscape.com)
  • Dr Penkert and coauthors note that the patient had previously received 80 infusions of natalizumab , which was stopped because of intermittent relapses and seroconversion to positive JC virus status. (medscape.com)
  • Moreover, the failure to show improvements in metrics of immunologic resilience during hospitalization is a prognosticator of worse outcomes. (globalhealthnewswire.com)
  • Dr. Greenspan acknowledged that immunologic staging is a daunting task, with the details of obtaining data and establishing a staging system yet to be developed. (cancernetwork.com)
  • For comparative purposes, the researchers evaluated metrics of immunologic resilience in 13,461 individuals without COVID-19. (globalhealthnewswire.com)
  • They should review immunization status at every visit, and administer the HPV vaccine at any time-including during sick visits. (aafp.org)
  • Personalized therapy tailored for mutation status is something to expect in the coming years for colorectal cancer treatment, notes Tanios S. Bekaii-Saab, MD. (cancernetwork.com)
  • The variability and immunologic importance of the genes in this complex makes these ideal candidates for identifying parental lineage, evaluating genetic diversity and predicting susceptibility to specific pathogens. (vin.com)
  • Preliminary verbal interaction with these donors revealed consumption of self-judged quantity of iron tablets to be a prevalent practice among them as a compensatory attempt to maintain hemoglobin status at qualifying level despite frequent blood donation (unpublished observation). (scirp.org)